Abstract:
:The assessment of new attachment after periodontal treatment has been the focus of continuous research. An approach to longitudinally examine the deposition of cementum was devised by using fluorescence microscopy (FL), contact microradiography (CMR), and toluidine blue staining (TBS) after the injection of three labeling agents known to be incorporated within newly mineralized tissues with different tones: tetracycline, calcein, and alizarin complexion. Three adult Japanese monkeys (male, 6.0 to 8.3 Kg weight) were used for this experiment. Bone defects were surgically created in 24 mandibular sites and a copper plate was inserted for a period of 4 weeks to promote microbial colonization to form periodontal pockets. Scaling and root planing (baseline) were then performed, and the fluorescent agents were administered twice weekly leaving a 1 week interval between the different agents. The mandibular specimens were fixed in neutralized formalin and embedded in polyester resin. Undecalcified sections were prepared 3, 6, and 9 weeks after baseline. Cementum regeneration was confirmed in 18 out of 24 sites; in 6 samples only epithelial proliferation was observed. Regeneration could be seen as early as 2 weeks after debridement. Cementum was identified by observation under FL of a labeled structure, discrimination in the degree of mineralization of dentin by CMR, and by the presence of functional collagen fibers and location of the epithelial border by TBS. In this study the use of three different labeling agents using the three observation techniques was shown to be effective for the longitudinal assessment of cementum regeneration.
journal_name
J Periodontoljournal_title
Journal of periodontologyauthors
Ogura N,Mera T,Sato F,Ishikawa Idoi
10.1902/jop.1991.62.4.284subject
Has Abstractpub_date
1991-04-01 00:00:00pages
284-91issue
4eissn
0022-3492issn
1943-3670journal_volume
62pub_type
杂志文章abstract:BACKGROUND:The objective of this study was to histologically evaluate periodontal healing following flap surgery in intrabony periodontal defects to determine the influence of the number of bone walls on periodontal regeneration. METHODS:One-, 2-, and 3-wall intrabony periodontal defects were surgically produced at th...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2004.75.2.229
更新日期:2004-02-01 00:00:00
abstract:BACKGROUND:The rehabilitation of the oral cavity with dental implants has become a predictable treatment modality. However, there have been only a few direct comparisons evaluating the submerged and nonsubmerged placement techniques. The purpose of this study was to characterize radiographic peri-implant bone changes f...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1999.70.3.248
更新日期:1999-03-01 00:00:00
abstract::Gingival incisions were performed distal to each of the two lower incisors on 25 adult male guinea pigs. For every animal, electrosection with an electrosurgical scalpel was used on one side, and a conventional scalpel was used on the other. The surgical instruments in all cases were brought into direct contact with p...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1975.46.1.40
更新日期:1975-01-01 00:00:00
abstract::A new flap design for placement of implants into osseous defects has been described. The flap design can be used in anterior and posterior areas of human subjects. Photographs of representative cases are presented. Wound healing always occurred by primary intention and without evidence of immediate graft exfoliation. ...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1985.56.4.204
更新日期:1985-04-01 00:00:00
abstract:BACKGROUND:Gingiva is composed of attached and marginal (free) gingiva and interdental papilla. Increasing esthetic demands in dentistry have created a need to restore all parts of the gingiva. However, the interdental papilla has limited regeneration potential compared to other parts of the gingiva. It also is more su...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2007.060165
更新日期:2007-02-01 00:00:00
abstract:BACKGROUND:Generalized aggressive periodontitis is described as a clinical entity affecting both deciduous and permanent dentition with extensive alveolar bone loss, mobility, and exfoliation of all or many teeth. Controversy exists on dental implant use to restore missing dentition in younger patients. METHODS:This c...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2001.72.3.411
更新日期:2001-03-01 00:00:00
abstract::The responses of four tooth/site groupings to periodontal therapy were evaluated. Eighty-two patients with periodontitis were treated in a split mouth design with coronal scaling, root planing, modified Widman surgery, and flap with osseous resectional surgery. Patients were evaluated prior to therapy, 4 weeks post-Ph...
journal_title:Journal of periodontology
pub_type: 临床试验,杂志文章
doi:10.1902/jop.1990.61.3.173
更新日期:1990-03-01 00:00:00
abstract::A retrospective study was conducted of 620 patients in a periodontal practice over the years 1960 to 1982. Various periodontal therapies were assessed by using careful office protocols, meticulous record-keeping and well-defined outcome criteria. Four treatment outcome categories were used: two representing satisfacto...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1985.56.5.253
更新日期:1985-05-01 00:00:00
abstract::Cyclosporine A (CsA) and verapamil are two agents used in renal transplantation, both of which are suspected of inducing gingival overgrowth. This study was conducted to investigate the effect of verapamil on the severity and prevalence of CsA-induced gingival overgrowth. Fifty-one (51) renal transplant recipients (to...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1996.67.11.1201
更新日期:1996-11-01 00:00:00
abstract:BACKGROUND:Compliance to periodontal maintenance therapy (PMT) is essential for long-term periodontal health. Between PMT visits, patients must maintain good oral hygiene. A dentifrice with demonstrable clinical benefits for use between PMT visits would be highly desirable. The aim of this clinical study was to investi...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1002/JPER.20-0721
更新日期:2020-12-17 00:00:00
abstract:BACKGROUND:Epidemiological studies have suggested that there is a genetic component to susceptibility to chronic periodontitis. Studies in humans and in animal models have suggested that some of the important components may be polymorphisms in key immunological genes. METHODS:This paper summarizes previously published...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2005.76.11-S.2042
更新日期:2005-11-01 00:00:00
abstract:BACKGROUND:Various forms of stress behavior were documented and in patients with periodontitis their relationship with periodontal disease was investigated. METHODS:Eighty-nine patients with different forms of chronic periodontitis were included in this retrospective case-control study. They were all undergoing period...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2002.73.11.1343
更新日期:2002-11-01 00:00:00
abstract:BACKGROUND:Platelet-rich fibrin (PRF) has recently been applied in osseous regeneration. The aim of the present study is to explore the efficacy of PRF in treatment of intrabony defects (IBDs) in aggressive periodontitis. METHODS:Fifty-four IBDs in 17 patients were treated either with autologous PRF with open flap deb...
journal_title:Journal of periodontology
pub_type: 杂志文章,随机对照试验
doi:10.1902/jop.2017.120661
更新日期:2017-11-01 00:00:00
abstract::This review discusses the rationale for using guided tissue regeneration therapy. The review not only attempts to clarify the concept of selective tissue regeneration using non-resorbable and resorbable barriers, but to discuss differences in healing events after treatment with the two types of barriers together with ...
journal_title:Journal of periodontology
pub_type: 杂志文章,meta分析
doi:10.1902/jop.1991.62.3.171
更新日期:1991-03-01 00:00:00
abstract::This investigation was conducted on seven individuals referred for treatment of moderate adult periodontitis. Twenty-eight sites with an average probing depth of 5.6 +/- 0.9 mm were evaluated. One tooth per jaw quadrant was randomly assigned to receive one of the following treatments: (I) no treatment, i.e., control; ...
journal_title:Journal of periodontology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1902/jop.1988.59.5.301
更新日期:1988-05-01 00:00:00
abstract:BACKGROUND:Members of the matrix metalloproteinase (MMP) family have been shown to be involved in periodontal disease. Risk factors for periodontal disease include tobacco smoking. Cigarette smoke condensate (CSC) is comprised of thousands of chemicals. Nicotine is one of the active components in tobacco. This study co...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2010.100540
更新日期:2011-07-01 00:00:00
abstract::Interleukin-1 beta (IL-1 beta) is the predominant form of IL-1 produced by macrophages. IL-1 beta possesses numerous and diverse biological activities. Several of these activities, including fibroblast proliferation, potentiation of the immune response, and stimulation of bone resorption may be of relevance to the pat...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1991.62.1.36
更新日期:1991-01-01 00:00:00
abstract:BACKGROUND:Periodontitis and osteoporosis are characterized by the loss of bone mass. Osteocalcin levels have been postulated as a marker of inhibition of bone formation. The aim of the present study was to assess plasma, saliva, and gingival crevicular fluid (GCF) levels of osteocalcin and correlate them with periodon...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2005.76.4.513
更新日期:2005-04-01 00:00:00
abstract:BACKGROUND:The great variability of periodontal and systemic responses to experimental periodontitis reflects the inherent pathogenic complexity of mice models and could limit the resulting interpretations and their extension to human diseases. This study compared the effect of Porphyromonas gingivalis (Pg) infection a...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2012.110540
更新日期:2013-03-01 00:00:00
abstract:BACKGROUND:The aim of the present study was to evaluate the effect of strict supragingival plaque control on the subgingival microbiota in smokers and never-smokers. Research into the impact of supragingival plaque control on the number of subgingival bacteria has resulted in contradictory findings. Real-time polymeras...
journal_title:Journal of periodontology
pub_type: 临床试验,杂志文章
doi:10.1902/jop.2008.070558
更新日期:2008-12-01 00:00:00
abstract:BACKGROUND:This study compared 6-month and 3-year outcomes for root coverage (RC) by coronally advanced flap (CAF) procedures in localized gingival recessions. METHODS:Two centers, that had participated in a 6-month multinational multicenter randomized clinical trial (RCT), followed up 18 patients with 36 Miller Class...
journal_title:Journal of periodontology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1902/jop.2017.160767
更新日期:2017-07-01 00:00:00
abstract::Ultrasonic scalers may be operated at different power settings which may influence the final therapeutic result. The displacement amplitude of the scaling tip may affect scaling efficiency or the degree of root surface damage. This investigation aimed to determine whether there was any difference in periodontal healin...
journal_title:Journal of periodontology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1902/jop.1995.66.9.756
更新日期:1995-09-01 00:00:00
abstract:BACKGROUND:Many studies have shown that periodontal disease can be successfully treated. However, there is limited documentation as to what happens when periodontal disease is left untreated. This study examined patients in a private practice who were diagnosed with periodontal disease and did not complete any treatmen...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2003.74.5.672
更新日期:2003-05-01 00:00:00
abstract:BACKGROUND:Buccal gingival recession is a prevalent problem in populations with a high standard of oral hygiene and is very often associated with a non-carious cervical lesion, complicating treatment. The purpose of this report is to show three cases treated by an integrated periodontal and restorative dentistry approa...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2007.060402
更新日期:2007-06-01 00:00:00
abstract:BACKGROUND:There is limited information about two-part implants placed in subcrestal positions. The aim of this study is to retrospectively evaluate the 1-year outcome of implants placed non-submerged and in a subcrestal position. METHODS:Records of 50 consecutive partially edentulous patients restored with dental imp...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2009.090317
更新日期:2010-03-01 00:00:00
abstract:BACKGROUND:There has been an explosion in research into possible associations between periodontitis and various systemic diseases and conditions. AIM:To review the evidence for associations between periodontitis and various systemic diseases and conditions, including chronic obstructive pulmonary disease (COPD), pneum...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2013.1340020
更新日期:2013-04-01 00:00:00
abstract:BACKGROUND:The efficacy of various partial-mouth recording (PMR) systems is analyzed in the evaluation of periodontal status, using index teeth and different combinations of quadrants. METHODS:The study group was formed of 108 adults aged 25 to 65 years old. A full-mouth examination (FME) was performed in all particip...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2013.130389
更新日期:2014-06-01 00:00:00
abstract::Proposing to place endosseous implants is an integral facet of dental treatment plans. Their insertion is usually associated with a low incidence of untoward events. However, despite careful planning, surgical complications can arise: infection, intraoral hemorrhage, wound dehiscence, postoperative pain, lack of prima...
journal_title:Journal of periodontology
pub_type: 杂志文章,评审
doi:10.1902/jop.2008.070067
更新日期:2008-08-01 00:00:00
abstract::A system of nomenclature for deformities of the alveolar process is presented. Descriptive, familiar topographic terms are used (crater, trench, moat, ramp and plane), and specific criteria are given for each term. Two hundred randomly selected osseous deformities in dry skulls were classified by two examiners at inde...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1984.55.6.336
更新日期:1984-06-01 00:00:00
abstract::This review examines specific aspects of orthodontic treatment and periodontal health, namely the effects of orthodontic banded attachments on periodontal disease and more specifically the microflora found around the gingival margins. This review highlights critical developments in orthodontic techniques and microbiol...
journal_title:Journal of periodontology
pub_type: 杂志文章,评审
doi:10.1902/jop.1996.67.2.78
更新日期:1996-02-01 00:00:00