Abstract:
BACKGROUND:Distraction of the periosteum results in the formation of new bone in the gap between the periosteum and the original bone. We postulate that the use of a barrier membrane would be beneficial for new bone formation in periosteal distraction. METHODS:To selectively influence the contribution of the periosteum, a distraction plate with perforations was used alone or covered by a collagen barrier membrane. All animals were subjected to a 7-day latency period and a 10-day distraction period with a rate of 0.1 mm/day. Four animals per group with or without a barrier membrane were sacrificed at 2, 4, and 6 weeks after the end of the distraction. The height of new bone generated relative to the areas bound by the parent bone and the periosteum was determined by histomorphometric methods. RESULTS:New bone was found in all groups. At the periphery of the distraction plate, significant differences in bone height were found between the hinge and the distraction screw for the group without barrier membrane at 2 weeks (0.39 ± 0.19 mm) compared to 4 weeks (0.84 ± 0.44 mm; P = 0.002) and 6 weeks (1.06 ± 0.39 mm; P = 0.004). Differences in maximum bone height with and without a barrier membrane were observed laterally to the distraction plate at 2 weeks (1.22 ± 0.64 versus 0.55 ± 0.14 mm; P = 0.019) and 6 weeks (1.61 ± 0.56 versus 0.73 ± 0.33 mm; P = 0.003) of the consolidation period. CONCLUSION:Within the limitations of the present study, the application of a barrier membrane may be considered beneficial for new bone formation induced by periosteal distraction.
journal_name
J Periodontoljournal_title
Journal of periodontologyauthors
Saulacic N,Schaller B,Bosshardt DD,Buser D,Jaun P,Haeniwa H,Iizuka Tdoi
10.1902/jop.2011.110418subject
Has Abstractpub_date
2012-06-01 00:00:00pages
757-65issue
6eissn
0022-3492issn
1943-3670journal_volume
83pub_type
杂志文章abstract:BACKGROUND:The analysis of samplings from periodontal pockets is important in the diagnosis and therapy of periodontitis. In this study, three different sampling techniques were compared to determine whether one method yielded samples suitable for the reproducible and simultaneous determination of bacterial load, cytok...
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pub_type: 杂志文章
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pub_type: 杂志文章
doi:10.1902/jop.1987.58.8.569
更新日期:1987-08-01 00:00:00
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journal_title:Journal of periodontology
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pub_type: 杂志文章
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更新日期:2012-03-01 00:00:00
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pub_type: 杂志文章
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pub_type: 杂志文章
doi:10.1902/jop.2006.050108
更新日期:2006-02-01 00:00:00
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