Biochemical and clinical factors influencing oral malodor in periodontal patients.

Abstract:

:The amounts of volatile sulfur compounds (VSC) and methyl mercaptan/hydrogen sulfide ratio in mouth air from patients with periodontal involvement were 8 times greater than those of control subjects. Our studies demonstrated that, in patients with periodontal disease: 1) the concentration of disulfide, which is converted to VSC, increased in proportion to the total pocket depth; 2) 60% of the VSC was produced from the tongue surface; 3) the amount of tongue coating was 4 times greater than in control subjects; and 4) VSC production and the methyl mercaptan/hydrogen sulfide ratio of the tongue coating were increased. 2-Ketobutyrate, which is a byproduct of the metabolism of methionine to methyl mercaptan, was higher in the saliva of patients with periodontal disease. This implies that metabolism of methionine to methyl mercaptan increases in the oral cavity of patients with periodontal pockets. Since free L-methionine, rather than protein, is the main source for methyl mercaptan, we estimated the methionine supply from the gingival fluid into the oral cavity of patients with periodontal involvement. The results showed that the ratio of methionine to whole free amino acids was significantly higher than that of cysteine. Our studies suggest that not only microorganisms, but also the tongue coating and gingival fluid are factors which enhance VSC production in patients with periodontal disease.

journal_name

J Periodontol

authors

Yaegaki K,Sanada K

doi

10.1902/jop.1992.63.9.783

subject

Has Abstract

pub_date

1992-09-01 00:00:00

pages

783-9

issue

9

eissn

0022-3492

issn

1943-3670

journal_volume

63

pub_type

杂志文章,评审
  • A combination of a chemically modified doxycycline and a bisphosphonate synergistically inhibits endotoxin-induced periodontal breakdown in rats.

    abstract:BACKGROUND:Chemically modified non-antimicrobial tetracyclines (CMTs) have been shown to inhibit pathologically elevated collagenase (and other matrix metalloproteinase, MMP) activity and bone resorption in vivo and in vitro. METHODS:In the current study, suboptimal doses of CMT-8 (a non-antimicrobial chemically modif...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2001.72.8.1069

    authors: Llavaneras A,Ramamurthy NS,Heikkilä P,Teronen O,Salo T,Rifkin BR,Ryan ME,Golub LM,Sorsa T

    更新日期:2001-08-01 00:00:00

  • Peri-implant soft tissue phenotype modification and its impact on peri-implant health: A systematic review and network meta-analysis.

    abstract:BACKGROUND:The peri-implant soft tissue phenotype (PSP) encompasses the keratinized mucosa width (KMW), mucosal thickness (MT), and supracrestal tissue height (STH). Numerous approaches to augment soft tissue volume around endosseous dental implants have been investigated. To what extent PSP modification is beneficial ...

    journal_title:Journal of periodontology

    pub_type: 杂志文章,评审

    doi:10.1002/JPER.19-0716

    authors: Tavelli L,Barootchi S,Avila-Ortiz G,Urban IA,Giannobile WV,Wang HL

    更新日期:2021-01-01 00:00:00

  • The use of blade implants in a selected population of partially edentulous adults. A five-year report.

    abstract::Based on the findings observed after the insertion of 33 blade implants in 23 patients, ages 31 to 74, for periods up to 60 months, the following conclusions can be made: (1) The blade implant is a technically feasible procedure which can be maintained in the mouth for period up to 5 years, although some degree of bon...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1976.47.1.19

    authors: Smithloff M,Fritz ME

    更新日期:1976-01-01 00:00:00

  • Body fat rather than body mass index is associated with gingivitis - A southern Brazilian cross-sectional study.

    abstract:BACKGROUND:This cross-sectional study aimed to evaluate the association between body mass index (BMI) and body fat with gingivitis in 613 adults of Porto Alegre, Brazil. METHODS:Individuals with at least four teeth were included in this study. They were identified through a multi-stage probability sampling, considerin...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1002/JPER.17-0292

    authors: Muniz FWMG,Costa RDSA,Cavagni J,Milanesi FC,Hilgert JB,Gomes SC,Oppermann RV,Rösing CK

    更新日期:2018-04-01 00:00:00

  • Levels of interferon-gamma and transcription factor T-bet in progressive periodontal lesions in patients with chronic periodontitis.

    abstract:BACKGROUND:Periodontitis is an infection with an episodic pattern of tissue-support destruction. During the generation of a primary CD4(+) T helper 1 (Th1) response, interferon-gamma (IFN-gamma) acts as a positive regulator by selectively inducing Th1 differentiation through increased transcription of T-bet. The aims o...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2009.080287

    authors: Dutzan N,Vernal R,Hernandez M,Dezerega A,Rivera O,Silva N,Aguillon JC,Puente J,Pozo P,Gamonal J

    更新日期:2009-02-01 00:00:00

  • Long-term success of implants replacing a single molar.

    abstract:BACKGROUND:The aim of this study was to assess the long-term success and survival rates of implants replacing a single molar between two natural teeth and to evaluate the influence of implant characteristics on implant success. METHODS:The study was based on a consecutive cohort of 81 patients who received implants to...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2006.060005

    authors: Levin L,Laviv A,Schwartz-Arad D

    更新日期:2006-09-01 00:00:00

  • The further localization of antibody on cemental tissue.

    abstract::In order to increase our understanding of the immunologic aspects of periodontal disease, three groups of extracted human teeth were evaluated for the presence of antibody on the cementum surface. Antibody was demonstrated by direct immunofluorescence using monospecific antibody with human alpha , gamma and upsilon ch...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1982.53.3.168

    authors: Everhart DL,Dahab O,Wolff L,Stahl SS

    更新日期:1982-03-01 00:00:00

  • A Novel Rat Model of Polymicrobial Peri-Implantitis: A Preliminary Study.

    abstract:BACKGROUND:Peri-implantitis is a complex polymicrobial biofilm-induced inflammatory osteolytic gingival infection that results in orofacial implant failures. To the best knowledge of the authors, there are no preclinical in vivo studies in implant dentistry that have investigated the inflammatory response to known micr...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2016.160273

    authors: Koutouzis T,Eastman C,Chukkapalli S,Larjava H,Kesavalu L

    更新日期:2017-02-01 00:00:00

  • Root coverage procedures for treating single and multiple recession-type defects: An updated Cochrane systematic review.

    abstract:BACKGROUND:This updated Cochrane systematic review (SR) evaluated the efficacy of different root coverage (RC) procedures in the treatment of single and multiple gingival recessions (GR). METHODS:We included randomized controlled trials (RCTs) only of at least 6 months' duration evaluating Miller's Class I or II GR (≥...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1002/JPER.19-0079

    authors: Chambrone L,Ortega MAS,Sukekava F,Rotundo R,Kalemaj Z,Buti J,Prato GPP

    更新日期:2019-12-01 00:00:00

  • Prevalence of different types of accessory canals in the furcation area of third molars.

    abstract:BACKGROUND:Although there are several studies that show the prevalence and diameter of accessory root canals in the furcation area, there is a scarceness of studies that observe the trajectory and different types of cavo-interradicular canals. The aim of this study was to verify the prevalence of the different morpholo...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2006.060112

    authors: Zuza EP,Toledo BE,Hetem S,Spolidório LC,Mendes AJ,Rosetti EP

    更新日期:2006-10-01 00:00:00

  • Analysis of consecutively placed loaded root-form and plate-form implants in adult Macaca mulatta monkeys.

    abstract::The present paper describes 36 consecutively treated non-human primates (Macaca mulatta) as part of a balanced block design study to examine osseointegration in root- and plate-form implants prepared by atraumatic preparation of bone. Clinical measurements around selected teeth and digital radiology were utilized to m...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1996.67.12.1322

    authors: Fritz ME,Braswell LD,Koth D,Jeffcoat M,Reddy M,Brogan D,Cotsonis G,Winter M,Lemons JE

    更新日期:1996-12-01 00:00:00

  • Histologic evaluation of the effects of intrasulcular toothbrushing on human sulcular epithelium.

    abstract::Nineteen young adult Caucasian males had an average Gingival Index Score of 0.47. Each was asked to demonstrate his present method of toothbrushing: thirteen used the scrub method, and six combined the scrub and roll methods. Control gingival tissue specimens were taken from the mandibular left first bicuspid or first...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1978.49.4.163

    authors: Fry HR,App GR

    更新日期:1978-04-01 00:00:00

  • A minimally invasive surgical approach for periodontal regeneration: surgical technique and observations.

    abstract::Increasingly, patients referred to periodontists have undergone some form of non-surgical periodontal treatment prior to their referral. As a result of this, there is an increased need to treat isolated, rather than generalized, periodontal defects. A surgical technique that utilizes small incisions and a limited acce...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1999.70.12.1547

    authors: Harrel SK

    更新日期:1999-12-01 00:00:00

  • Interleukin-1β Gene Expression in Human Oral Polymorphonuclear Leukocytes.

    abstract::Oral polymorphonuclear leukocytes (pmn) were obtained from 10 adult donors in good oral health using a method employing repeated mouth rinse collection. Interleukin-1β (IL-1β) mRNA was detected in freshly obtained cells by blot hybridization of total cellular RNA with a biotin labeled cDNA probe. Supernates from oral ...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1995.66.9.761

    authors: Hendley TM,Steed RB,Galbraith GMP

    更新日期:1995-09-01 00:00:00

  • Guided tissue regeneration with dentin biomodification.

    abstract::This study was undertaken to provide histologic observations on the effectiveness of citric acid and tetracycline HCl root surface demineralization when used in conjunction with guided tissue regeneration (GTR) procedures. Eight beagle dogs with naturally-occurring periodontitis were initially treated with scaling and...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1993.64.11.1052

    authors: Dyer BL,Caffesse RG,Nasjleti CE,Morrison EC

    更新日期:1993-11-01 00:00:00

  • Posterior implant single-tooth replacement and status of adjacent teeth during a 10-year period: a retrospective report.

    abstract:BACKGROUND:The purpose of this case series study was to evaluate posterior single-tooth implant survival and the long-term conditions of the adjacent teeth. METHODS:A retrospective evaluation of 1,162 consecutive patients with a single missing posterior tooth treated with 1,377 external hex implants supporting 1,365 r...

    journal_title:Journal of periodontology

    pub_type: 杂志文章,多中心研究

    doi:10.1902/jop.2008.080188

    authors: Misch CE,Misch-Dietsh F,Silc J,Barboza E,Cianciola LJ,Kazor C

    更新日期:2008-12-01 00:00:00

  • A chlorhexidine-containing methacrylic gel as a periodontal dressing.

    abstract::The modification of a methacrylic gel for use as a periodontal dressing was attempted. The increased adhesion and rigidity of the resultant material appeared consistent with the clinical findings. Satisfactory retention of the dressing was found in 85% of those placed on a group of patients attending for periodontal s...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1975.46.8.465

    authors: Addy M,Douglas WH

    更新日期:1975-08-01 00:00:00

  • Periodontal soft tissue non-root coverage procedures: a systematic review from the AAP Regeneration Workshop.

    abstract:BACKGROUND:Gingival augmentation procedures around natural teeth and dental implants are performed to facilitate plaque control, to improve patient comfort, to prevent future recession, and in conjunction with restorative, orthodontic, or prosthetic dentistry. The aim of this study is to answer the most common question...

    journal_title:Journal of periodontology

    pub_type: 杂志文章,评审

    doi:10.1902/jop.2015.130684

    authors: Kim DM,Neiva R

    更新日期:2015-02-01 00:00:00

  • Guided bone regeneration for dehiscence and fenestration defects on implants using an absorbable polymer barrier.

    abstract:BACKGROUND:Guided bone regeneration (GBR) using a non-absorbable barrier has provided clinicians the ability to place implants in sites compromised by insufficient bone, including immediate extraction sites. Recent evidence suggests that successful GBR outcomes may be possible using bioabsorbable polymer barriers. MET...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2001.72.2.250

    authors: Rosen PS,Reynolds MA

    更新日期:2001-02-01 00:00:00

  • RANKL upregulation associated with periodontitis and Porphyromonas gingivalis.

    abstract:BACKGROUND:Receptor activator of nuclear factor-kappa B (NF-kappaB) ligand (RANKL) and osteoprotegerin (OPG) are critical for homeostatic control of osteoclast activity, suggesting their vital roles in the progression of bone loss in periodontitis. In this study, the expression of RANKL and OPG mRNA and the relationshi...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2007.060398

    authors: Wara-aswapati N,Surarit R,Chayasadom A,Boch JA,Pitiphat W

    更新日期:2007-06-01 00:00:00

  • A new hypothesis of periodontal homeostasis.

    abstract::A review of the experimental evidence evidence on marrow inhibition by implanted roots has shown that an inhibitory factor is present in all root surfaces. It is most marked in periodontally diseased roots and least in periodontally healthy roots. It is hypothesized that a "marked" amount would inhibit periodontal cel...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1980.51.1.49

    authors: Morris ML

    更新日期:1980-01-01 00:00:00

  • Clustering by periodontitis-associated factors-A novel application to NHANES data.

    abstract:BACKGROUND:Unsupervised clustering is a method used to identify heterogeneity among groups and homogeneity within a group of patients. Without a prespecified outcome entry, the resulting model deciphers patterns that may not be disclosed using traditional methods. This is the first time such clustering analysis is appl...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1002/JPER.20-0489

    authors: Ghassib IH,Batarseh FA,Wang HL,Borgnakke WS

    更新日期:2020-12-14 00:00:00

  • Periodontal Conditions of Sites Treated With Gingival Augmentation Surgery Compared With Untreated Contralateral Homologous Sites: An 18- to 35-Year Long-Term Study.

    abstract:BACKGROUND:The aim of this split-mouth study is to compare long-term (18 to 35 years) periodontal conditions of sites treated with gingival augmentation procedures (GAPs) and untreated homologous contralateral sites. METHODS:Forty-seven patients with 64 sites (test group), with lack of attached gingiva associated with...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2016.160284

    authors: Agudio G,Cortellini P,Buti J,Pini Prato G

    更新日期:2016-12-01 00:00:00

  • A multi-center study comparing dual acid-etched and machined-surfaced implants in various bone qualities.

    abstract:BACKGROUND:A major reason for the success of modern dental implant systems has been the development of implant designs that enhance direct bone-implant interface. Surface roughness has been a factor in this success and different systems have utilized very different implant surface roughness. The major purpose of this s...

    journal_title:Journal of periodontology

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1902/jop.2001.72.10.1384

    authors: Khang W,Feldman S,Hawley CE,Gunsolley J

    更新日期:2001-10-01 00:00:00

  • A rapid chairside test for the severity of periodontal disease using gingival fluid.

    abstract::A study was done in an attempt to develop a simple test for the severity of periodontal disease. Gingival fluid collected on filter paper was tested for protein content, and the resulting color was compared to standard color filters. Tissue was excised and prepared for histologic examination. The inflammatory cell inf...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1978.49.8.391

    authors: Dombrowski JC,Schacterle GR,Livne JK,White DK

    更新日期:1978-08-01 00:00:00

  • A retrospective cohort study on peri-implant complications in implants up to 10 years of functional loading in periodontally compromised patients.

    abstract:BACKGROUND:Prevalence of peri-implantitis is directly proportional to the time of functional loading. The aim of this retrospective study was to assess the survival and success rates as well as the incidence of peri-implantitis among patients with a history of periodontitis and among implants with 1 to 10 years of func...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1002/JPER.18-0715

    authors: Pandolfi A,Rinaldo F,Pasqualotto D,Sorrentino F,La Torre G,Guerra F

    更新日期:2019-12-20 00:00:00

  • Smoking May Lead to Marginal Bone Loss Around Non-Submerged Implants During Bone Healing by Altering Salivary Microbiome: A Prospective Study.

    abstract:BACKGROUND:This prospective and controlled study elucidates the impact of smoking on the salivary microbiome and its further influence on marginal bone loss (MBL) around an implant during a 3-month bone-healing period. METHODS:Saliva samples were collected preoperatively from 20 periodontally healthy patients with sin...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2017.160808

    authors: Duan X,Wu T,Xu X,Chen D,Mo A,Lei Y,Cheng L,Man Y,Zhou X,Wang Y,Yuan Q

    更新日期:2017-12-01 00:00:00

  • Periodontal disease as a risk indicator for poor physical fitness: a cross-sectional observational study.

    abstract:BACKGROUND:Physical inactivity has been associated with poor oral health. The aim of this study is to assess whether periodontal disease is a risk indicator for poor physical fitness. METHODS:This cross-sectional study included 111 males who performed a physical fitness test (PFT) composed of four exercises: 1) push-u...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2014.140270

    authors: Oliveira JA,Hoppe CB,Gomes MS,Grecca FS,Haas AN

    更新日期:2015-01-01 00:00:00

  • EDTA gel root conditioning: lack of effect on clinical and radiographic outcomes of intrabony defect treatment with enamel matrix derivative.

    abstract:BACKGROUND:The adjunctive use of enamel matrix derivative (EMD) in the surgical therapy of intrabony defects results in improved outcomes compared to surgical debridement alone. However, the role of EDTA root conditioning in EMD therapy has not been investigated. The purpose of this study was to compare the 12-month ou...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2006.77.1.103

    authors: Parashis AO,Tsiklakis K,Tatakis DN

    更新日期:2006-01-01 00:00:00

  • Scanning electron microscopic observations of cell populations and bacterial contamination of membranes used for guided periodontal tissue regeneration in humans.

    abstract::Fourteen intrabony periodontal defects and six furcation defects (Class II) were treated by a flap procedure which included the use of a polytetrafluoroethylene membrane to allow guided tissue regeneration. After 4 to 6 weeks of healing, the membranes were retrieved and examined by scanning electron microscopy for the...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1990.61.8.515

    authors: Selvig KA,Nilveus RE,Fitzmorris L,Kersten B,Khorsandi SS

    更新日期:1990-08-01 00:00:00