Abstract:
BACKGROUND:The peri-implant soft tissue phenotype (PSP) encompasses the keratinized mucosa width (KMW), mucosal thickness (MT), and supracrestal tissue height (STH). Numerous approaches to augment soft tissue volume around endosseous dental implants have been investigated. To what extent PSP modification is beneficial for peri-implant health has been subject of debate in the field of implant dentistry. The aim of this systematic review was to analyze the evidence regarding the efficacy of soft tissue augmentation procedures aimed at modifying the PSP and their impact on peri-implant health. METHODS:A comprehensive search was performed to identify clinical studies that involved soft tissue augmentation around dental implants and reported findings on KMW, MT, and/or STH changes. The effect of the intervention on peri-implant health was also assessed. Selected articles were classified based on the general type of surgical approach to increase PSP, either bilaminar or an apically positioned flap (APF) technique. A network meta-analysis including only randomized-controlled trials (RCTs) reporting on PSP outcomes was conducted to assess and compare different techniques. RESULTS:A total of 52 articles were included in the qualitative analysis, and 23 RCTs were included as part of the network meta-analysis. Sixteen RCTs reported the outcomes of PSP modification therapy with bilaminar techniques, whereas 7 involved the use of APF. The analysis showed that bilaminar techniques in combination with soft tissue grafts (connective tissue graft [CTG], collagen matrix [CM], and acellular dermal matrix [ADM]) resulted in a significant increase in MT compared to non-augmented sites. In particular, CTG and ADM were associated with higher MT gain as compared to CM and non-augmented sites. However, no significant differences in KMW were observed across different bilaminar techniques. PSP modification via a bilaminar approach utilizing either CTG or CM showed beneficial effects on marginal bone level stability. APF-based approaches in combination with free gingival graft (FGG), CTG, CM, or ADM showed a significant KMW gain compared to non-augmented sites. However, compared to APF alone, only FGG exhibited a significantly higher KMW gain. APF with any evaluated soft tissue graft was associated with with reduction of probing depth, soft tissue dehiscence and plaque index compared to non-augmented sites compared to non-augmented sites. The evidence regarding the effect of PSP modification via APF-based approaches on peri-implant marginal bone loss or preservation is inconclusive. CONCLUSIONS:Bilaminar approach involving CTG or ADM obtained the highest amount of MT gain, whereas APF in combination with FGG was the most effective technique for increasing KMW. KMW augmentation via APF was associated with a significant reduction in probing depth, soft tissue dehiscence and plaque index, regardless of the soft tissue grafting material employed, whereas bilaminar techniques with CTG or CM showed beneficial effects on marginal bone level stability.
journal_name
J Periodontoljournal_title
Journal of periodontologyauthors
Tavelli L,Barootchi S,Avila-Ortiz G,Urban IA,Giannobile WV,Wang HLdoi
10.1002/JPER.19-0716subject
Has Abstractpub_date
2021-01-01 00:00:00pages
21-44issue
1eissn
0022-3492issn
1943-3670journal_volume
92pub_type
杂志文章,评审abstract::Multiple periodontal lesions were the presenting features leading to a diagnosis of multiple myeloma in a 38-year-old male. Ulceration and bleeding from a rapidly growing retromolar myelomatous mass, multiple foci of alveolar bone destruction and cortical expansion together with multifocal skeletal destruction were th...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1990.61.2.132
更新日期:1990-02-01 00:00:00
abstract::This clinical study was designed to determine if mechanical instrumentation (root planing) of the exposed root is useful in treating gingival recession caused by traumatic toothbrushing following a coronally advanced flap (CAF). Ten patients with high levels of oral hygiene (full-mouth plaque score <20%), from 25 to 5...
journal_title:Journal of periodontology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1902/jop.1999.70.9.1064
更新日期:1999-09-01 00:00:00
abstract::Wounds were prepared in the oral cavity of 15 rabbits and five dogs, and an enzyme-solubilized calfskin collagen was placed over the surgery sites on one side. The contralateral sides acted as controls. Results indicated that the membrane was biologically acceptable to the oral mucosa of rabbits and dogs. Th collagen ...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1979.50.5.250
更新日期:1979-05-01 00:00:00
abstract:BACKGROUND:Non-surgical periodontal treatment with an Er:YAG laser has been shown to result in significant clinical attachment level gain; however, clinical results have not been established on a long-term basis following Er:YAG laser treatment. Therefore, the aim of the present study was to present the 2-year results ...
journal_title:Journal of periodontology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1902/jop.2003.74.5.590
更新日期:2003-05-01 00:00:00
abstract::T-cell subsets extracted from chronically inflamed periodontal tissues were identified using monoclonal antibodies, and their functional activity was analysed using the autologous mixed lymphocyte reaction (AMLR). Tissue was obtained from a total of 33 adult periodontitis (AP) patients and 6 normal/marginal gingivitis...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1987.58.8.569
更新日期:1987-08-01 00:00:00
abstract::In recent years there has been a dramatic increase in the use of nonprecious alloy and porcelain crowns in clinical dentistry. The alloy in these restorations frequently contains a high percentage (greater than 70%) of nickel. Most cases of metal hypersensitivity are related to nickel, and clinical manifestations of t...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1987.58.7.486
更新日期:1987-07-01 00:00:00
abstract:BACKGROUND:The objective of this study is to determine whether simvastatin consumption and hyperlipidemia are associated with a worse periodontal condition and specific bone activity biomarkers. METHODS:This cross-sectional and analytic study includes 73 patients divided into three groups: 1) simvastatin-treated patie...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2014.130652
更新日期:2014-10-01 00:00:00
abstract::The modification of a methacrylic gel for use as a periodontal dressing was attempted. The increased adhesion and rigidity of the resultant material appeared consistent with the clinical findings. Satisfactory retention of the dressing was found in 85% of those placed on a group of patients attending for periodontal s...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1975.46.8.465
更新日期:1975-08-01 00:00:00
abstract:BACKGROUND:Several studies have indicated a relationship between rheumatoid arthritis and periodontal disease. The aim of this study was to investigate the association between the circulating proinflammatory mediators tumor necrosis factor-alpha (TNF-alpha), interleukin-1beta, prostaglandin E(2), serotonin, rheumatoid ...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2008.070599
更新日期:2008-09-01 00:00:00
abstract::THE MORBIDITY and incidence of bacteremia in periodontal surgery with or without cephalexin prophylaxis were assessed in adults on the basis of clinical evaluations and blood cultures. Cephalexin reduced the incidence of polymicrobic bacteremias. There was no correlation between objective signs of tissue healing and a...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1982.53.5.319
更新日期:1982-05-01 00:00:00
abstract:BACKGROUND:Physical inactivity has been associated with poor oral health. The aim of this study is to assess whether periodontal disease is a risk indicator for poor physical fitness. METHODS:This cross-sectional study included 111 males who performed a physical fitness test (PFT) composed of four exercises: 1) push-u...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2014.140270
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:The subgingival microbiota as well as determination of markers such as associated pathogens is still in the focus of dental research. The aim of this controlled clinical trial was to determine clinical applicability of a newly developed chairside bacterial test (CST) for the most relevant periodontal pathoge...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1002/JPER.19-0180
更新日期:2020-03-01 00:00:00
abstract:BACKGROUND:Considering xenogeneic collagen matrix (CM) and enamel matrix derivative (EMD) characteristics, it is suggested that their combination could promote superior clinical outcomes in root coverage procedures. Thus, the aim of this parallel, double-masked, dual-center, randomized clinical trial is to evaluate cli...
journal_title:Journal of periodontology
pub_type: 杂志文章,随机对照试验
doi:10.1902/jop.2017.170126
更新日期:2017-12-01 00:00:00
abstract:BACKGROUND:There are four key studies in the periodontology literature reporting the correlation between supernumerary teeth and aggressive periodontitis. The aim of this study is to detect such a relationship. METHODS:Patients with supernumerary teeth were identified retrospectively from their orthopantomographs and ...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2004.75.11.1458
更新日期:2004-11-01 00:00:00
abstract:BACKGROUND:The need for keratinized mucosa (KM) or immobile keratinized mucosa (i.e., attached mucosa [AM]) for the maintenance of osseointegrated endosseous dental implants has been controversial. The purpose of this study was to investigate the significance of KM in the maintenance of root-form dental implants with d...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2006.050393
更新日期:2006-08-01 00:00:00
abstract:BACKGROUND:Many studies have shown that periodontal disease can be successfully treated. However, there is limited documentation as to what happens when periodontal disease is left untreated. This study examined patients in a private practice who were diagnosed with periodontal disease and did not complete any treatmen...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2003.74.5.672
更新日期:2003-05-01 00:00:00
abstract:BACKGROUND:A hypothesis of an increased risk for destructive periodontal diseases due to psychological stress has long been promoted. However, the research on stress and periodontal disease is still in its infancy. One of the reasons is thought to be that there is no suitable animal model for investigating the relation...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2004.75.2.306
更新日期:2004-02-01 00:00:00
abstract:BACKGROUND:Clinical attachment level (CAL) and bone height (radiographic or clinical) are two well-accepted endpoint measures for periodontal clinical trials; however, neither one has been shown to be more predictive of long-term success than the other. We propose using a composite endpoint analysis combining clinical ...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2006.050275
更新日期:2006-08-01 00:00:00
abstract::This paper briefly reviews the historical relationship between oral medicine and periodontics. The reasons for including structured clinical oral medicine in a postdoctoral program in periodontics are discussed. Problems and solutions to such an integrated program are outlined. Guidelines for broadening the base of th...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1986.57.7.426
更新日期:1986-07-01 00:00:00
abstract:BACKGROUND:The present study was designed to evaluate the effect, if any, of citric acid root demineralization in the outcome of subepithelial connective tissue grafts performed to cover localized gingival recessions. METHODS:Thirty-six patients participated, each providing one gingival recession; 19 received citric a...
journal_title:Journal of periodontology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1902/jop.2000.71.4.568
更新日期:2000-04-01 00:00:00
abstract:BACKGROUND:The aim of this study was to assess the long-term success and survival rates of implants replacing a single molar between two natural teeth and to evaluate the influence of implant characteristics on implant success. METHODS:The study was based on a consecutive cohort of 81 patients who received implants to...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2006.060005
更新日期:2006-09-01 00:00:00
abstract:BACKGROUND:Reports from studies of twins, disease aggregation in families, animal models for periodontal disease, and various genetic-analysis studies have determined that genetics plays a role in the susceptibility to periodontal disease. The purpose of this pilot study is to evaluate the effect of genetics on periodo...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2010.100189
更新日期:2011-04-01 00:00:00
abstract:BACKGROUND:Study objectives were 1) to estimate diagnostic capacity of clinical parameters, receptor activator of nuclear factor kappa-B (RANKL) and osteoprotegerin (OPG) to diagnose healthy peri-implant condition (HI), peri-implant mucositis (PIM) and peri-implantitis (PIMP) by assessing respective diagnostic accuracy...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1002/JPER.19-0283
更新日期:2020-07-01 00:00:00
abstract:BACKGROUND:Purified recombinant human platelet-derived growth factor BB (rhPDGF-BB) is a potent wound healing growth factor and stimulator of the proliferation and recruitment of both periodontal ligament (PDL) and bone cells. The hypothesis tested in this study was that application of rhPDGF-BB incorporated in bone al...
journal_title:Journal of periodontology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1902/jop.2003.74.9.1282
更新日期:2003-09-01 00:00:00
abstract:BACKGROUND:Implant failures are rare but do occur. Mechanical factors are certainly important in implant failures; so are biologic, iatrogenic, and functional factors. Mobility is the cardinal sign of implant failure. Three major etiologic factors have been suggested for implant failures: infection, impaired healing, a...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2003.74.3.385
更新日期:2003-03-01 00:00:00
abstract:BACKGROUND:The purpose of this study was to investigate the effect of two modes of delivery of non-surgical periodontal therapy on patient experience of pain and oral health-related quality of life (OHQoL). METHODS:Fifty-nine patients with mild to moderate periodontitis received non-surgical therapy using a piezo-cera...
journal_title:Journal of periodontology
pub_type: 杂志文章,随机对照试验
doi:10.1902/jop.2008.070394
更新日期:2008-06-01 00:00:00
abstract:BACKGROUND:Procedures to improve peri-implant soft-tissue outcomes of single, immediately placed implants are a topic of interest. This systematic review investigates the effect of various surgical and restorative interventions on implant mid-buccal mucosal level. METHODS:An electronic search of five databases (Januar...
journal_title:Journal of periodontology
pub_type: 杂志文章,评审
doi:10.1902/jop.2013.130064
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:Combined periodontal regenerative technique (CPRT) is a surgical procedure that combines the use of barrier membranes with a filling material in the treatment of periodontal defects. The effectiveness of CPRT has been evaluated in many studies in comparison to GTR with membranes alone, but conflicting result...
journal_title:Journal of periodontology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1902/jop.2002.73.2.158
更新日期:2002-02-01 00:00:00
abstract:BACKGROUND:No information exists on periodontitis-associated subgingival microbiota from Turkey. We determined the occurrence, interspecies relationships, and clonal characteristics for a group of periodontal bacteria in a Turkish study population. METHODS:Subgingival microbial samples were obtained from patients with...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2003.74.6.803
更新日期:2003-06-01 00:00:00
abstract::A randomized, double-blind, clinical study was done to assess the microbiological and clinical effects of metronidazole plus amoxicillin (M+A) as the only therapy in 46 patients with moderate to advanced progressive adult periodontitis. Patients were included in the study after at least 2 sites showed > or =2 mm clini...
journal_title:Journal of periodontology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1902/jop.1998.69.11.1291
更新日期:1998-11-01 00:00:00