A combination of a chemically modified doxycycline and a bisphosphonate synergistically inhibits endotoxin-induced periodontal breakdown in rats.

abstract：BACKGROUND:The long-term survival of dental implants depends, in part, on control of bacterial infection in the peri-implant region. Periodontal pathogens colonized implants symptomatic through infection, whereas the microbiota of successful implants was similar to that of periodontal health. This study examined the im...

journal_title：Journal of periodontology

authors： Lee KH,Maiden MF,Tanner AC,Weber HP

更新日期：1999-02-01 00:00:00

abstract：BACKGROUND:Aspartate aminotransferase (AST) is an enzyme normally confined to the cytoplasm of cells, but released to the exracellular environment upon cell death. Its levels are associated with the severity of experimental gingivitis and the loss of periodontal attachement. The aim of the present study was to investig...

journal_title：Journal of periodontology

authors： Paolantonio M,Di Placido G,Tumini V,Di Stilio M,Contento A,Spoto G

更新日期：2000-07-01 00:00:00

abstract：:To date, there are no ultrastructural studies that have examined untreated chronic periodontal pockets immediately following dental debridement with an oral irrigation device. This study used both scanning electron microscopic and transmission electron microscopic methodology to examine previously untreated human peri...

journal_title：Journal of periodontology

authors： Cobb CM,Rodgers RL,Killoy WJ

更新日期：1988-03-01 00:00:00

abstract：BACKGROUND:To our knowledge, prospective studies (matched for sex, smoking, and diabetes) that investigated the influence of compliance in the progression of periodontitis and tooth loss in periodontal maintenance therapy (PMT) programs were not previously reported. METHODS:A total of 58 regular complier (RC) and 58 e...

journal_title：Journal of periodontology

authors： Oliveira Costa F,Miranda Cota LO,Pereira Lages EJ,Medeiros Lorentz TC,Soares Dutra Oliveira AM,Dutra Oliveira PA,Costa JE

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:The aim of this study was to determine the plaque-removing ability of a curved bristle toothbrush compared to a conventional, straight bristle, manual toothbrush. METHODS:The study group consisted of 100 volunteers 16 to 24 years of age from a professional engineering college. A four-week post-prophylaxis, ...

journal_title：Journal of periodontology

authors： Chava VK

更新日期：2000-05-01 00:00:00

abstract：:Histologic sections from six autopsy cases which from a clinical point of view fitted into the criteria of periodontosis were examined with the aim at evaluating the role of subgingival plaque in the etiology of the loss of attachment in this condition. The following pertinent observations were made: 1. The subgingiva...

journal_title：Journal of periodontology

authors： Waerhaug J

更新日期：1976-11-01 00:00:00

abstract：BACKGROUND:Metformin, a classical treatment for diabetes mellitus, has shown sound anti-inflammatory effects. Emerging studies have focused on the mechanism underlying inflammation-related diabetic complications, such as diabetic periodontitis. Herein, we investigated the anti-inflammatory effects of metformin on the N...

journal_title：Journal of periodontology

authors： Zhou X,Zhang P,Wang Q,Ji N,Xia S,Ding Y,Wang Q

更新日期：2019-02-19 00:00:00

abstract：BACKGROUND:The aim of the present study is to assess the osteogenic differentiation of rat bone marrow stromal cells (RBMCs) in β-tricalcium phosphate (β-TCP) blocks containing extracellular matrix (ECM) produced by human alveolar bone periosteal cells (HABPCs). METHODS:HABPCs were cultured in β-TCP blocks for 1 week ...

journal_title：Journal of periodontology

authors： Iwasaki K,Munemasa N,Tago K,Nemoto K,Tsujigami H,Sugaya A,Deguchi S

更新日期：2013-10-01 00:00:00

abstract：:Acro-osteolysis ( Hadju - Cheney ) Syndrome is a rare disorder of bone metabolism characterized by progressive destruction of the distal phalangeal bone, curvature of the spine, aplasia of the facial sinuses, and persistence of the cranial sutures. The purpose of this manuscript is to focus on the description of the o...

journal_title：Journal of periodontology

authors： Allen CM,Claman L,Feldman R

更新日期：1984-04-01 00:00:00

abstract：BACKGROUND:Enamel matrix derivative (EMD) has been shown to promote several aspects of periodontal regeneration in vitro and in vivo. Recently, a bioengineered tissue (DG) was developed to promote wound healing of chronic skin ulcers. This pilot study sought to assess the effects of EMD and DG, alone or in combination,...

journal_title：Journal of periodontology

authors： Hovey LR,Jones AA,McGuire M,Mellonig JT,Schoolfield J,Cochran DL

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND:The comparative treatment response of children and young adults with localized aggressive periodontitis treatment (LAgP) affecting primary and permanent dentition is unknown. The objective of this study is to evaluate the influence of non-surgical periodontal therapy with adjunctive systemic antibiotics on t...

journal_title：Journal of periodontology

authors： Merchant SN,Vovk A,Kalash D,Hovencamp N,Aukhil I,Harrison P,Zapert E,Bidwell J,Varnado P,Shaddox LM

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:Little evidence is available regarding the effects of long-term periodontal infection on diabetes mellitus (DM) control. The aim of this retrospective cohort study is to evaluate influence of periodontal status on changes of glycated hemoglobin (HbA1c) levels of patients with type 2 DM (DMt2). METHODS:Eight...

journal_title：Journal of periodontology

authors： Costa KL,Taboza ZA,Angelino GB,Silveira VR,Montenegro R Jr,Haas AN,Rego RO

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Behçet's disease is a multisystem disorder of unknown etiology, affecting predominantly the oral mucosa, skin, and eyes. Recurrent and painful episodes of oral ulcerations interfere with regular oral hygiene leading to rapid bacterial plaque accumulation. The aims of this study were to evaluate the periodont...

journal_title：Journal of periodontology

authors： Celenligil-Nazliel H,Kansu E,Ebersole JL

更新日期：1999-12-01 00:00:00

abstract：BACKGROUND:Increased collagenolytic activity, characteristic of uncontrolled diabetes, may compromise collagen membrane (CM) survival. Tetracycline (TCN) possesses anticollagenolytic properties and delays CM degradation in healthy animals. This study evaluates the degradation of TCN--immersed and -non-immersed CMs in r...

journal_title：Journal of periodontology

authors： Eliezer M,Nemcovsky C,Romanos G,Kozlovsky A,Tal H,Kolerman R,Weinreb M,Moses O

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:Full-mouth scaling (FMS) is claimed by some researchers to be superior to standard scaling and root planing (SRP). The aim of the present study was to evaluate clinical outcomes of two modalities of non-surgical periodontal therapy for patients with chronic periodontitis. METHODS:In a prospective, randomize...

journal_title：Journal of periodontology

authors： Knöfler GU,Purschwitz RE,Jentsch HF

更新日期：2007-11-01 00:00:00

abstract：:Temporary splints to immobilize periodontally diseased teeth were made by fiber glass bonded and attached to the teeth with acid-etch technique with BIS-GMA resin. Twenty-one splints were made. Observation time ranged from 4 to 14 months. During the observation only one splint fractured and was repaired while the othe...

journal_title：Journal of periodontology

authors： Friskopp J,Blomlöf L,Söder PO

更新日期：1979-04-01 00:00:00

abstract：:Plasma cells are widely distributed in inflamed periodontal tissues, the adjacent periodontal ligament and nearby alveolar bone spaces, of old rats (20 and 27 months) raised on a conventional diet in a normal laboratory environment. Electron microscopy revealed three morphologic types (or perhaps stages) of these cell...

journal_title：Journal of periodontology

authors： Garant PR,Paik KS,Cho MI

更新日期：1983-04-01 00:00:00

abstract：:Extracts of corn and some nuts were found to ubiquitously stimulate both adult and newborn cord blood lymphocytes to transform and produce a factor chemotactic for monocytes. This indicates that corn and nuts contain a mitogen and are potential stimulators of the cellular immune response. The exposure of lymphocytes t...

journal_title：Journal of periodontology

authors： Radentz WH,Baker J,Altman LC,Oppenheim JJ

更新日期：1975-09-01 00:00:00

abstract：:Mycoplasma have been identified in one case of juvenile periodontitis by size, morphology, hemadsorption and cultural techniques. These microorganisms were found on the surface of the tooth, on the surface of pocket epithelium and invading the gingival epithelium and adjacent connective tissue. These observations sugg...

journal_title：Journal of periodontology

authors： Newman MG,Saglie R,Carranza FA Jr,Kaufman AK

更新日期：1984-10-01 00:00:00

abstract：:This study clinically analyzed the efficacy of a connective tissue graft including the periosteum used as a barrier to enhance new attachment and osseous regeneration. Fifteen patients, with no systemic diseases, and adult periodontitis including 2 Class II furcation involvements in lower molars comprised the study gr...

journal_title：Journal of periodontology

authors： Lekovic V,Kenney EB,Carranza FA,Martignoni M

更新日期：1991-12-01 00:00:00

abstract：BACKGROUND:Periodontitis is an infection with an episodic pattern of tissue-support destruction. During the generation of a primary CD4(+) T helper 1 (Th1) response, interferon-gamma (IFN-gamma) acts as a positive regulator by selectively inducing Th1 differentiation through increased transcription of T-bet. The aims o...

journal_title：Journal of periodontology

authors： Dutzan N,Vernal R,Hernandez M,Dezerega A,Rivera O,Silva N,Aguillon JC,Puente J,Pozo P,Gamonal J

更新日期：2009-02-01 00:00:00

abstract：:The cross-sectional relationship between severe loss of periodontal attachment (LPA) and worsening immune status due to HIV infection was evaluated in 474 HIV-infected subjects (416 men, 58 women) aged 18 to 49 years who had been classified at stages 1 through 6 of the Walter Reed Army Institute of Research (WR) Stagi...

journal_title：Journal of periodontology

authors： Tomar SL,Swango PA,Kleinman DV,Burt BA

更新日期：1995-06-01 00:00:00

abstract：BACKGROUND:Chronic kidney disease (CKD) is a worldwide health problem with increasing prevalence and poor outcomes, including severe cardiovascular disease and renal osteodystrophy. With advances in medical treatment, patients with CKD are living longer and require oral care. The aim of this study is to determine the e...

journal_title：Journal of periodontology

authors： Lee MM,Chu EY,El-Abbadi MM,Foster BL,Tompkins KA,Giachelli CM,Somerman MJ

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND:Osteoblasts and periodontal ligament stem cells (PDLSCs) play an important role in maintaining physiologic function of periodontal tissues and participating in periodontal regeneration. Elucidation of interactions between osteoblasts and PDLSCs will aid understanding of periodontal regeneration mechanisms. T...

journal_title：Journal of periodontology

authors： Yu M,Wang L,Ba P,Li L,Sun L,Duan X,Yang P,Yang C,Sun Q

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:T cell cytokine profiles in the spleens and anti-Porphyromonas gingivalis antibodies in the sera of P. gingivalis-immunized BALB/c (H-2d), CBA/CaH (H-2k), C57BL6 (H-2b), and DBA/2J (H-2d, C5 deficient) mice were examined. METHODS:Mice were immunized either by intraperitoneal injections of P. gingivalis oute...

journal_title：Journal of periodontology

authors： Gemmell E,Winning TA,Grieco DA,Bird PS,Seymour GJ

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND:The goal of guided tissue regeneration-based root coverage (GTRC) is to repair gingival recession via new attachment formation. Numerous clinical trials have been conducted utilizing the concept of GTR to promote root coverage. Most GTRC studies have had relatively small sample sizes and have not utilized po...

journal_title：Journal of periodontology

authors： Al-Hamdan K,Eber R,Sarment D,Kowalski C,Wang HL

更新日期：2003-10-01 00:00:00

abstract：BACKGROUND:Little is known about systemic, environmental, and periodontal risk factors of gingival recessions. This study identifies variables related to buccal gingival recessions in an adult French population; this study uses data collected in the First National Periodontal and Systemic Examination Survey. METHODS:T...

journal_title：Journal of periodontology

authors： Sarfati A,Bourgeois D,Katsahian S,Mora F,Bouchard P

更新日期：2010-10-01 00:00:00

abstract：:This tribute was written by Dr. E. Brady Hancock, who was a student of and who succeeded Dr. Timothy J. O'Leary as chair of the Department of Periodontics at Indiana University. Dr. O'Leary served as co-editor of the Journal of Periodontologyfrom 1970 until 1988. ...

journal_title：Journal of periodontology

authors：

更新日期：2004-09-01 00:00:00

abstract：BACKGROUND:Subantimicrobial-dose doxycycline (SDD) is widely used as an adjunctive treatment to scaling and root planing (SRP), but its long-term effectiveness remains controversial. The purpose of this systematic review was to assess the actual evidence of the effectiveness of SRP + SDD compared to SRP + placebo in th...

journal_title：Journal of periodontology

authors： Sgolastra F,Petrucci A,Gatto R,Giannoni M,Monaco A

更新日期：2011-11-01 00:00:00

abstract：:Demineralized bone matrix (DBM) is widely used in the repair of pathologies associated with skeletal defects and periodontal diseases. The present study was directed at establishing in vivo and in vitro models for a quantitative assessment of the osteoinductivity of DBM before clinical use. Athymic mice were used in a...

journal_title：Journal of periodontology

authors： Zhang M,Powers RM Jr,Wolfinbarger L Jr

更新日期：1997-11-01 00:00:00