Abstract:
BACKGROUND:Alanine aminopeptidase (ALAP) and dipeptidyl peptidase IV (DPPIV) are ectopeptidases that play a role in collagen degradation and are thought to be involved in the destruction of periodontal tissue. This study compared the activities of salivary ALAP and DPPIV in patients with periodontitis and periodontally healthy subjects. The correlations of enzyme activities with clinical variables and the presence of Porphyromonas gingivalis were also evaluated. METHODS:Whole saliva was collected from 30 periodontally healthy subjects, 30 localized chronic periodontitis (LCP) patients, and 30 generalized chronic periodontitis (GCP) patients to determine the activities of ALAP and DPPIV. The presence of P. gingivalis in subgingival plaque was detected by polymerase chain reaction. Periodontal clinical assessments included probing depth, clinical attachment level, and bleeding on probing. RESULTS:The activities of DPPIV in the LCP and GCP groups were not significantly different from one another, but both groups had significantly higher enzyme activities than the periodontally healthy group (P = 0.001). DPPIV activity was positively correlated with all clinical parameters and the prevalence of P. gingivalis. The ALAP activities were not significantly different among the three study groups. There was no significant correlation of ALAP activity with any of the clinical and bacterial parameters. CONCLUSION:DPPIV, but not ALAP, activity is associated with periodontitis and the presence of P. gingivalis.
journal_name
J Periodontoljournal_title
Journal of periodontologyauthors
Aemaimanan P,Sattayasai N,Wara-aswapati N,Pitiphat W,Suwannarong W,Prajaneh S,Taweechaisupapong Sdoi
10.1902/jop.2009.090233subject
Has Abstractpub_date
2009-11-01 00:00:00pages
1809-14issue
11eissn
0022-3492issn
1943-3670journal_volume
80pub_type
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abstract::The risk of transmitting airborne pathogens is an important consideration in dentistry and has acquired special significance in the context of recent respiratory disease epidemics. The purpose of this review, therefore, is to examine (1) what is currently known regarding the physics of aerosol creation, (2) the types ...
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journal_title:Journal of periodontology
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journal_title:Journal of periodontology
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journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1984.55.6.336
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journal_title:Journal of periodontology
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更新日期:2017-06-01 00:00:00
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journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1990.61.9.590
更新日期:1990-09-01 00:00:00
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journal_title:Journal of periodontology
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1999-09-01 00:00:00
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journal_title:Journal of periodontology
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journal_title:Journal of periodontology
pub_type: 杂志文章
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更新日期:2005-11-01 00:00:00
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journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1994.65.6.583
更新日期:1994-06-01 00:00:00
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journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2014.130577
更新日期:2014-10-01 00:00:00
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journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2006.050380
更新日期:2006-09-01 00:00:00
abstract:BACKGROUND:Alveolar bone regeneration is frequently necessary prior to placement of implants. Efforts to improve wound healing have focused on factors that may enhance bone formation following guided bone regeneration (GBR) techniques alone or in combination with bone replacement graft materials. Recent reports suggest...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2000.71.10.1654
更新日期:2000-10-01 00:00:00
abstract::Gingival biopsies of the mesial papilla area of the first molar were obtained from each patient at 0-, 14- and 21-day intervals during plaque formation. The biopsies were fixed, serially sectioned, and Gram-stained. The incidence and distribution of the bacteria-like structures were studied by microscopy. In all the s...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1987.58.12.837
更新日期:1987-12-01 00:00:00
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journal_title:Journal of periodontology
pub_type: 杂志文章
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更新日期:2014-02-01 00:00:00
abstract:BACKGROUND:Some studies have reported an association between gestational diabetes mellitus (GDM) and periodontitis. The aim of the present study is to analyze this potential association and the influence of risk variables associated with GDM. METHODS:This case-control study includes 360 women, 90 with GDM and 270 cont...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2012.120350
更新日期:2013-09-01 00:00:00
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journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1993.64.11.1052
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