Commentary: A Translational Medicine Approach to Tooth Transplantation.

Abstract:

:The autogenous tooth transplantation approach to replace missing teeth has been in use for a long time. Different surgical techniques have been developed to improve prognosis and longevity of transplanted teeth with complete root formation. Many factors reportedly affected short- and long-term success of the procedure: complications such as ankylosis and root resorption up to the tooth exfoliation have occurred frequently. Several studies have appeared on this issue over the years. However, outcomes of transplantations have not yet been conclusively determined as no randomized clinical trials have been published on this issue, and their effectiveness has been evaluated only in observational studies. On the other hand, interesting information from specific experimental studies on the healing pattern of the interface between the root surface and alveolar bone in the replantation/transplantation model, and from non-related studies dealing with mechanically induced periodontal trauma, has been available and potentially useful since the 1970s to 1980s. However, this information has not been incorporated into clinical literature regarding tooth autotransplantation. This commentary aims to show how information from related and unrelated experimental models was translated to a clinical setting and led to a novel approach, successfully applied, in the autotransplantation of a multirooted tooth with completed root formation.

journal_name

J Periodontol

authors

Prato GP,Zuccati G,Clauser C

doi

10.1902/jop.2017.160820

subject

Has Abstract

pub_date

2017-06-01 00:00:00

pages

519-525

issue

6

eissn

0022-3492

issn

1943-3670

journal_volume

88

pub_type

杂志文章
  • Longitudinal observation of cementum regeneration through multiple fluorescent labeling.

    abstract::The assessment of new attachment after periodontal treatment has been the focus of continuous research. An approach to longitudinally examine the deposition of cementum was devised by using fluorescence microscopy (FL), contact microradiography (CMR), and toluidine blue staining (TBS) after the injection of three labe...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1991.62.4.284

    authors: Ogura N,Mera T,Sato F,Ishikawa I

    更新日期:1991-04-01 00:00:00

  • Comparison of surgical stripping; erbium-doped:yttrium, aluminum, and garnet laser; and carbon dioxide laser techniques for gingival depigmentation: a clinical and histologic study.

    abstract:BACKGROUND:Gingival melanin depigmentation procedures are commonly associated with recurrence of pigmentation, which starts with migration of melanocytes from the adjacent free gingiva. The extent and rate of recurrence varies according to the treatment modalities used and duration of follow-up. The aim of this study i...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2012.120094

    authors: Hegde R,Padhye A,Sumanth S,Jain AS,Thukral N

    更新日期:2013-06-01 00:00:00

  • The feasibility and reliability of using a home screening test to detect gingival inflammation.

    abstract::The purpose of this study was to evaluate the feasibility and reliability of using a home screening occult blood test to detect the presence of gingival inflammation. Fifty (50) healthy male and female subjects participated in this study. Pre- and post-stimulation saliva samples were obtained and tested for occult blo...

    journal_title:Journal of periodontology

    pub_type: 临床试验,杂志文章

    doi:10.1902/jop.1995.66.1.52

    authors: Kopczyk RA,Graham R,Abrams H,Kaplan A,Matheny J,Jasper SJ

    更新日期:1995-01-01 00:00:00

  • Clinical oral medicine. An exciting facet of postdoctoral periodontic training.

    abstract::This paper briefly reviews the historical relationship between oral medicine and periodontics. The reasons for including structured clinical oral medicine in a postdoctoral program in periodontics are discussed. Problems and solutions to such an integrated program are outlined. Guidelines for broadening the base of th...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1986.57.7.426

    authors: Hurt WC

    更新日期:1986-07-01 00:00:00

  • Estimation of pentraxin-3 levels in the gingival tissues of chronic and aggressive periodontitis participants: an in vivo study.

    abstract:BACKGROUND:Pentraxins are acute-phase proteins that belong to a family of evolutionarily conserved proteins, and they are considered markers of inflammation. Pentraxin-3 (PTX3) is a prototype of the long pentraxin group. It is suggested to play an important role in innate resistance against pathogens, regulation of inf...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2013.120718

    authors: Lakshmanan R,Jayakumar ND,Sankari M,Padmalatha O,Varghese S

    更新日期:2014-02-01 00:00:00

  • Association between periodontitis and chronic obstructive pulmonary disease in a Chinese population.

    abstract:BACKGROUND:A relationship between periodontitis and chronic respiratory disease has been suggested by recent studies. The aim of this study is to explore the association between periodontitis and chronic obstructive pulmonary disease (COPD) in a Chinese population. METHODS:We conducted a case-control study of 581 COPD...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2012.110472

    authors: Si Y,Fan H,Song Y,Zhou X,Zhang J,Wang Z

    更新日期:2012-10-01 00:00:00

  • Subgingival plaque removal using a new air-polishing device.

    abstract:BACKGROUND:The purpose of this study is to evaluate the safety, patient acceptance, and short-term microbiologic effect of a new air-polishing device in subjects in maintenance care with residual pockets > or =5 mm. METHODS:This was an examiner-masked, randomized, split-mouth clinical trial. A new disposable nozzle, a...

    journal_title:Journal of periodontology

    pub_type: 杂志文章,随机对照试验

    doi:10.1902/jop.2009.090394

    authors: Moëne R,Décaillet F,Andersen E,Mombelli A

    更新日期:2010-01-01 00:00:00

  • Evaluation of MicroRNA-146a and Its Targets in Gingival Tissues of Patients With Chronic Periodontitis.

    abstract:BACKGROUND:MicroRNAs (miRNAs) are a group of small non-coding RNAs that play an important role in the regulation of gene expression. miRNA-146a (miR-146a), a member of the miR-146 family, is involved in the control of inflammation. Periodontitis is a set of chronic inflammatory disorders of the tissues surrounding the ...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2015.150319

    authors: Motedayyen H,Ghotloo S,Saffari M,Sattari M,Amid R

    更新日期:2015-12-01 00:00:00

  • Monoclonal antibodies against integrin subunits alpha6 and beta1 inhibit migration of gingival epithelium in organ culture.

    abstract:BACKGROUND:The main problem in the posterior instrumental treatment of periodontitis is the re-epithelization of the periodontal defects, leading to the formation of an unphysiological, long junctional epithelium inhibiting the regeneration of periodontal attachment. A precondition for the re-epithelization is the inte...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1999.70.4.388

    authors: Gräber HG,Wilharm J,Conrads G

    更新日期:1999-04-01 00:00:00

  • A multi-center study comparing dual acid-etched and machined-surfaced implants in various bone qualities.

    abstract:BACKGROUND:A major reason for the success of modern dental implant systems has been the development of implant designs that enhance direct bone-implant interface. Surface roughness has been a factor in this success and different systems have utilized very different implant surface roughness. The major purpose of this s...

    journal_title:Journal of periodontology

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1902/jop.2001.72.10.1384

    authors: Khang W,Feldman S,Hawley CE,Gunsolley J

    更新日期:2001-10-01 00:00:00

  • Cyclosporine A upregulates platelet-derived growth factor B chain in hyperplastic human gingiva.

    abstract::Cyclosporine A (CSA) is a widely used immunosuppressant for transplant patients and is also used for the treatment of a wide variety of systemic diseases with immunologic components. A prominent side effect of CSA administration is gingival overgrowth (hyperplasia). It has been postulated that CSA alters fibroblast ac...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1996.67.3.271

    authors: Nares S,Ng MC,Dill RE,Park B,Cutler CW,Iacopino AM

    更新日期:1996-03-01 00:00:00

  • The relationship between clinical periodontal status and insulin-dependent diabetes mellitus. Results after 5 years.

    abstract::The clinical periodontal status of 44 insulin-dependent diabetic children and adolescents and 20 healthy control subjects was compared for a period of approximately 5 years. Fasting blood glucose, fructosamine, and glycosylated hemoglobin (HbA1) values were determined at baseline and 5 years later. The differences in ...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1997.68.2.136

    authors: Firatli E

    更新日期:1997-02-01 00:00:00

  • Magnesium-enriched hydroxyapatite compared to calcium sulfate in the healing of human extraction sockets: radiographic and histomorphometric evaluation at 3 months.

    abstract:BACKGROUND:Reduction of alveolar height and width after tooth extraction may present problems for implant placement, especially in the anterior maxilla where bone volume is important for biologic and esthetic reasons. Different graft materials have been proposed to minimize the reduction in ridge volume. The aim of thi...

    journal_title:Journal of periodontology

    pub_type: 杂志文章,随机对照试验

    doi:10.1902/jop.2009.080400

    authors: Crespi R,Capparè P,Gherlone E

    更新日期:2009-02-01 00:00:00

  • Assessment of risk for periodontal disease. I. Risk indicators for attachment loss.

    abstract::Specific risk indicators associated with either susceptibility or resistance to severe forms of periodontal disease were evaluated in a cross-section of 1,426 subjects, 25 to 74 years of age, mostly metropolitan dwellers, residing in Erie County, New York, and surrounding areas. The study sample exhibited a wide range...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1994.65.3.260

    authors: Grossi SG,Zambon JJ,Ho AW,Koch G,Dunford RG,Machtei EE,Norderyd OM,Genco RJ

    更新日期:1994-03-01 00:00:00

  • Localization of fibronectin in gingival connective tissue of the beagle dog. Ultrastructural detection with ferritin and peroxidase-conjugated antibodies.

    abstract::Ferritin and peroxidase-conjugated antibodies were used in an indirect antibody method to localize fibronectin in gingival connective tissues. Fibronectin was found in the basal lamina beneath the epithelium and endothelium. Collagen fibrils associated with the basement membranes were also heavily coated by fibronecti...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1986.57.7.413

    authors: Cho MI,Lee YL,Garant PR

    更新日期:1986-07-01 00:00:00

  • Effect of citric acid treatment on the migration of epithelium on root surfaces in vitro.

    abstract::Explants of bovine gingival mucosa were cultured for four days on scaled and citric acid-conditioned root surfaces. Demineralization of the hard tissue with citric acid exposed the collagenous matrix of the root. Undemineralized islands were frequently seen among the collagen fibers of the treated roots. When cultured...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1988.59.2.95

    authors: Larjava H,Salonen J,Häkkinen L,Närhi T

    更新日期:1988-02-01 00:00:00

  • Periodontal disease in patients from the original Kostmann family with severe congenital neutropenia.

    abstract:BACKGROUND:Patients with Kostmann syndrome (severe congenital neutropenia [SCN]) typically normalize their absolute neutrophil count (ANC) upon granulocyte colony-stimulating factor (G-CSF) therapy. However, although they no longer experience life-threatening bacterial infections, they frequently still have recurrent g...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2006.050191

    authors: Carlsson G,Wahlin YB,Johansson A,Olsson A,Eriksson T,Claesson R,Hänström L,Henter JI

    更新日期:2006-04-01 00:00:00

  • Generalized periodontitis associated with Chédiak-Higashi syndrome.

    abstract:BACKGROUND:Chédiak-Higashi syndrome (CHS) is a rare immunodeficient disorder. Patients with CHS are prone to severe periodontitis. To date, limited improvement following periodontal therapy has been reported. Thus, successful clinical outcomes in patients with CHS are of interest. METHODS:A 12-year-old girl was referr...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2008.070440

    authors: Bailleul-Forestier I,Monod-Broca J,Benkerrou M,Mora F,Picard B

    更新日期:2008-07-01 00:00:00

  • Bilateral subpontic osseous hyperplasia. A case report.

    abstract::A case of osseous hyperplasia under the pontics of fixed partial dentures in right and left mandibular first molar regions is presented. Radiographs showed hemispherical radio-opacities on the alveolar ridges. Histologic examination revealed the lesions were composed of a dense mass of mature bone with well-developed ...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1988.59.5.311

    authors: Takeda Y,Itagaki M,Ishibashi K

    更新日期:1988-05-01 00:00:00

  • Repigmentation of the gingiva following surgical injury.

    abstract::Oral melanin pigmentation is not uncommon in some races and ethnic groups. Repigmentation of depigmented oral mucosa has been described after chemical, thermal, surgical, pharmacologic or idiopathic factors. Information on the repigmentation of oral tissues after surgical procedures is extremely limited. The communica...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1986.57.1.48

    authors: Perlmutter S,Tal H

    更新日期:1986-01-01 00:00:00

  • Genetic dependence of the specific T-cell cytokine response to Porphyromonas gingivalis in mice.

    abstract:BACKGROUND:Susceptibility to periodontal infections may, in part, be genetically determined. Porphyromonas gingivalis is a major periodontopathogen, and the immune response to this organism requires T-cell help. The aim of the present study was to examine the specific T-cell cytokine responses to P. gingivalis outer me...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2002.73.6.591

    authors: Gemmell E,Carter CL,Bird PS,Seymour GJ

    更新日期:2002-06-01 00:00:00

  • Clinical Responses Following Periodontal Treatment by Local Drug Delivery.

    abstract::A 4-quadrant, single-blind study was designed to test the efficacy of periodontal disease therapy by local drug delivery. A delivery system made of extruded ethylene vinyl acetate fibers loaded with 25% USP tetracycline hydrochloride was placed and maintained in periodontal pockets for 10 days. The clinical effects of...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1985.56.11s.81

    authors: Goodson JM,Hogan PE,Dunham SL

    更新日期:1985-11-01 00:00:00

  • Generalized juvenile periodontitis: report of a familial case followed for 5 years.

    abstract::The case of a family, followed for 5 years and showing an exceptionally high prevalence of Generalized Juvenile Periodontitis (GJP), is presented. Two siblings were affected by a severe form of GJP meanwhile the dycorial twin of one was periodontally healthy. Both the affected siblings showed infection by Actinobacill...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1990.61.9.590

    authors: Sbordone L,Ramaglia L,Bucci E

    更新日期:1990-09-01 00:00:00

  • Periodontal disease as a risk indicator for poor physical fitness: a cross-sectional observational study.

    abstract:BACKGROUND:Physical inactivity has been associated with poor oral health. The aim of this study is to assess whether periodontal disease is a risk indicator for poor physical fitness. METHODS:This cross-sectional study included 111 males who performed a physical fitness test (PFT) composed of four exercises: 1) push-u...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2014.140270

    authors: Oliveira JA,Hoppe CB,Gomes MS,Grecca FS,Haas AN

    更新日期:2015-01-01 00:00:00

  • Autologous Platelet-Rich Fibrin in the Treatment of 3-Wall Intrabony Defects in Aggressive Periodontitis: A Randomized Controlled Clinical Trial.

    abstract:BACKGROUND:Platelet-rich fibrin (PRF) has recently been applied in osseous regeneration. The aim of the present study is to explore the efficacy of PRF in treatment of intrabony defects (IBDs) in aggressive periodontitis. METHODS:Fifty-four IBDs in 17 patients were treated either with autologous PRF with open flap deb...

    journal_title:Journal of periodontology

    pub_type: 杂志文章,随机对照试验

    doi:10.1902/jop.2017.120661

    authors: Bajaj P,Agarwal E,Rao NS,Naik SB,Pradeep AR,Kalra N,Priyanka N,Kumari M

    更新日期:2017-11-01 00:00:00

  • Effect of Periodontal Therapy With Amoxicillin-Metronidazole on Pharyngeal Carriage of Penicillin- and Erythromycin-Resistant Viridans Streptococci.

    abstract:BACKGROUND:Previous studies have focused on antibiotic resistance of Gram-negative bacteria before and after periodontal therapy. The purpose of this analysis is to assess changes in resistance patterns of the commensal Gram-positive microbiota. The viridans group streptococci (VGS) have been suggested to serve as rese...

    journal_title:Journal of periodontology

    pub_type: 杂志文章,随机对照试验

    doi:10.1902/jop.2015.150494

    authors: Mombelli A,Cionca N,Almaghlouth A,Cherkaoui A,Schrenzel J,Giannopoulou C

    更新日期:2016-05-01 00:00:00

  • Tissue response to titanium implants in the rat maxilla: ultrastructural and histochemical observations of the bone-titanium interface.

    abstract:BACKGROUND:The detailed mechanism of osseointegration, the most appropriate implant-bone interface, remains unclear in jaw tissues at the ultrastructural level in contrast to the many reports using long bones. The present study reports on tissue response to titanium-implantation on an animal model using rat maxilla. M...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2000.71.2.287

    authors: Futami T,Fujii N,Ohnishi H,Taguchi N,Kusakari H,Ohshima H,Maeda T

    更新日期:2000-02-01 00:00:00

  • Treatment of supra-alveolar-type defects by a simplified papilla preservation technique for access flap surgery with or without enamel matrix proteins.

    abstract:BACKGROUND:In this study, we compare the effectiveness of enamel matrix derivative (EMD) associated with a simplified papilla preservation flap (SPPF) technique to SPPF alone when surgically treating supra-alveolar-type defects. METHODS:Fifty patients, from 54 initially selected, presenting horizontal bone loss around...

    journal_title:Journal of periodontology

    pub_type: 杂志文章,随机对照试验

    doi:10.1902/jop.2012.120075

    authors: Di Tullio M,Femminella B,Pilloni A,Romano L,D'Arcangelo C,De Ninis P,Paolantonio M

    更新日期:2013-08-01 00:00:00

  • Periodontal wound healing with and without platelet-rich plasma: histologic observations and assessment of flap tensile strength.

    abstract:BACKGROUND:Platelet-rich plasma (PRP) has been promoted as a surgical adjunct to enhance hard and soft tissue wound healing. Although anecdotally reported to be of value, the results of controlled studies examining the added effects of PRP on surgical procedures have been mixed. The purpose of this study was to test th...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2009.080626

    authors: Powell CA,Bannister SR,Mackey SA,Maller SC,McDonnell HT,Deas DE

    更新日期:2009-06-01 00:00:00

  • Periodontitis is associated with systemic inflammation and vascular endothelial dysfunction in patients with lacunar infarct.

    abstract:BACKGROUND:Periodontitis has been associated with lacunar infarct (LI), a type of cerebral small vessel disease. The objective of this study was to ascertain whether periodontitis is associated with increased circulating levels of systemic inflammation and endothelial dysfunction biomarkers in patients with LI. METHOD...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1002/JPER.18-0560

    authors: Leira Y,Rodríguez-Yáñez M,Arias S,López-Dequidt I,Campos F,Sobrino T,D'Aiuto F,Castillo J,Blanco J

    更新日期:2019-05-01 00:00:00