Clinical evaluation and comparison of 2 topical anesthetics for pain caused by needle sticks and scaling and root planing.

Abstract:

BACKGROUND:Pain generated by needle sticks (Ns) for the delivery of local anesthetic and/or scaling and root planing (SRP) instrumentation is commonly addressed by the use of topical anesthetics, such as a benzocaine-gel preparation (BGP). Pain suppression following such use has been highly variable. Development of medicine-containing patches and adhesives for intraoral use have led to a new approach for topical anesthesia in the form of a transoral lidocaine delivery system (LDS). The purpose of this double-blind study was to evaluate the efficacy of the LDS and also to compare LDS with BGP for pain suppression to Ns and SRP. METHODS:One group of 20 subjects randomly received in both maxillary and mandibular molar-bicuspid areas LDS or BGP on one side and non-anesthetic control on the other side. A second group of 20 subjects compared the effectiveness of LDS directly with BGP in molar-bicuspid areas of both arches. Random order determined the selection for each anesthetic tested between the arches and bilateral. Pain perception was separately scored to a pain-inducing Ns simulation without anesthetic injection at each area and subsequently also to SRP using both a verbal pain scale (VPS) and a visual analog scale (VAS). RESULTS:VPS and VAS results analyzed by Bonferroni-adjusted Wilcoxon matched-pairs signed-rank tests found pain suppression scores significantly (P < 0.005) reduced for Ns by LDS to controls and to BGP. Comparing LDS directly with BGP, LDS was significantly (P < 0.05) more effective in reducing pain to Ns in both arches, to SRP in the maxillary arch, and equally effective as BGP in the mandibular arch. CONCLUSIONS:LDS is more effective than BGP for topical pain suppression to Ns and SRP in both arches.

journal_name

J Periodontol

authors

Carr MP,Horton JE

doi

10.1902/jop.2001.72.4.479

subject

Has Abstract

pub_date

2001-04-01 00:00:00

pages

479-84

issue

4

eissn

0022-3492

issn

1943-3670

journal_volume

72

pub_type

临床试验,杂志文章,随机对照试验
  • Commentary: incorporating patient-reported outcomes in periodontal clinical trials.

    abstract::The authors review patient-reported outcome (PRO) metrics for dentistry, and in particular, periodontics. The PRO commentary for periodontics includes a review of split-mouth, randomized, controlled clinical trial results that specifically tracked pain at different sites over time after intervention and provided guide...

    journal_title:Journal of periodontology

    pub_type: 杂志文章,评审

    doi:10.1902/jop.2014.130693

    authors: McGuire MK,Scheyer ET,Gwaltney C

    更新日期:2014-10-01 00:00:00

  • Altered healing following mucogingival surgery in a patient with Crohn's disease: a literature review and case report.

    abstract:BACKGROUND:Crohn's disease is a chronic inflammatory bowel disease characterized by uncertainty in etiology and pathogenesis occasionally with manifestations in oral mucous membranes. This report reviews the literature on Crohn's disease and presents a patient with Crohn's disease on continuous anti-inflammatory and im...

    journal_title:Journal of periodontology

    pub_type: 杂志文章,评审

    doi:10.1902/jop.2003.74.4.537

    authors: Andersen KM,Selvig KA,Leknes KN

    更新日期:2003-04-01 00:00:00

  • Protective effects of desipramine on alveolar bone in experimental periodontitis.

    abstract:BACKGROUND:Desipramine is a tricyclic antidepressant with immune-modulatory activity, whose effects on ligature-induced periodontitis are yet to be investigated. Hence, its actions on alveolar bone resorption, gingival collagen content and key inflammatory mediators were herewith analyzed. METHODS:A total of 60 male W...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1002/JPER.19-0569

    authors: Branco-de-Almeida LS,Franco GCN,Castro ML,Vieira MS,Galvão-Moreira LV,Cortelli SC,Anbinder AL,Kawai T,Rosalen PL

    更新日期:2020-12-01 00:00:00

  • Osteopromotion: a soft-tissue exclusion principle using a membrane for bone healing and bone neogenesis.

    abstract::The research reviewed in this paper constitutes a series of investigations intended to develop and evaluate a new membrane technique, which provides improved conditions for osteogenesis during healing of bone defects and restitution of earlier existing bone. The technique has also been shown to aid in bone grafting as...

    journal_title:Journal of periodontology

    pub_type: 杂志文章,评审

    doi:10.1902/jop.1993.64.11s.1116

    authors: Linde A,Alberius P,Dahlin C,Bjurstam K,Sundin Y

    更新日期:1993-11-01 00:00:00

  • Reproducibility of probing depth measurement by an experimental periodontal probe incorporating optical fiber sensor.

    abstract:BACKGROUND:An experimental periodontal sensor probe (SP) equipped with an optical fiber for recording function was developed. The aim was to test the intraexaminer reproducibility of probing using the SP and to assess the consistency with the manual probe (MP). METHODS:The SP was assembled with an external sheath cove...

    journal_title:Journal of periodontology

    pub_type: 杂志文章,随机对照试验

    doi:10.1902/jop.2011.110047

    authors: Ishihata K,Wakabayashi N,Wadachi J,Akizuki T,Izumi Y,Takakuda K,Igarashi Y

    更新日期:2012-02-01 00:00:00

  • Periodontal assessment by right- and left-handed examiners: is there a difference?

    abstract:BACKGROUND:Multiple factors that influence the precision of periodontal probing measurements have been identified. These factors can be categorized as being dependent upon host-related, probe-related, or examiner-related variables. However, the potential influence of examiner handedness (right or left) on the measureme...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2006.050185

    authors: Khan SM,Blanchard SB,Dowsett SA,Eckert GJ,Kowolik MJ

    更新日期:2006-07-01 00:00:00

  • Exposure to occupational noise and periodontitis in Korean workers.

    abstract:BACKGROUND:Chronic exposure to occupational noise is reported to cause a wide range of health problems. But, there are no reports on studies investigating the association between noise exposure and periodontitis. The purpose of this study was to examine the relationship between occupational noise exposure and periodont...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1002/JPER.17-0484

    authors: Shim SH,Han DH

    更新日期:2018-04-01 00:00:00

  • Transcriptomes in healthy and diseased gingival tissues.

    abstract:BACKGROUND:Clinical and radiographic measures are gold standards for diagnosing periodontitis but offer little information regarding the pathogenesis of the disease. We hypothesized that a comparison of gene expression signatures between healthy and diseased gingival tissues would provide novel insights in the pathobio...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2008.080139

    authors: Demmer RT,Behle JH,Wolf DL,Handfield M,Kebschull M,Celenti R,Pavlidis P,Papapanou PN

    更新日期:2008-11-01 00:00:00

  • Effect of citric acid and lyophilized autologous plasma on healing following periodontal flap surgery in monkeys.

    abstract::The purpose of this histologic, histometric, and autoradiographic study was to examine the effect of citric acid conditioning and lyophilized autologous plasma (LAP) application on healing following periodontal flap surgery. Mucoperiosteal flaps were elevated in six rhesus monkeys using the modified Widman flap proced...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1987.58.11.770

    authors: Nasjleti CE,Caffesse RG,Castelli WA,Smith BA,Lopatin DE,Kowalski CJ

    更新日期:1987-11-01 00:00:00

  • Sinus floor augmentation with simultaneous implant placement in the severely atrophic maxilla.

    abstract::Dental implant placement associated with augmentation of the sinus floor in the severely atrophic maxilla can be performed in 1- or 2-surgical stages, depending on the height of the residual alveolar bone. A minimum of 4 to 5 mm of residual alveolar bone height is recommended for a 1-stage surgical procedure. The pres...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1998.69.12.1397

    authors: Peleg M,Mazor Z,Chaushu G,Garg AK

    更新日期:1998-12-01 00:00:00

  • Matrix metalloproteinases, tissue inhibitors of matrix metalloproteinases, and inflammation in cyclosporine A-induced gingival enlargement: a pilot in vitro study using a three-dimensional model of the human oral mucosa.

    abstract:BACKGROUND:It has been suggested that cyclosporine A (CsA) induces gingival enlargement by promoting an increase in the gingival extracellular matrix (ECM). Nonetheless, the variable occurrence of CsA-induced gingival enlargement in patients receiving this medication indicates a multifactorial pathogenesis. Clinical ob...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2012.120224

    authors: Johanson M,Zhao XR,Huynh-Ba G,Villar CC

    更新日期:2013-05-01 00:00:00

  • Cytokines and bone-related factors in systemically healthy patients with chronic periodontitis and patients with type 2 diabetes and chronic periodontitis.

    abstract:BACKGROUND:This study compares the levels of cytokines and bone-related factors in the gingival crevicular fluid (GCF) of systemically healthy patients with chronic periodontitis (CP); and better-controlled, and poorly controlled patients with type 2 diabetes and CP. METHODS:Thirty-seven patients with type 2 diabetes ...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2011.100643

    authors: Ribeiro FV,de Mendonça AC,Santos VR,Bastos MF,Figueiredo LC,Duarte PM

    更新日期:2011-08-01 00:00:00

  • Root coverage using the coronally positioned flap with or without a subepithelial connective tissue graft.

    abstract:BACKGROUND:Various surgical techniques have been proposed for treating gingival recession. This randomized clinical trial compared the coronally positioned flap (CPF) alone or in conjunction with a subepithelial connective tissue graft (SCTG) in the treatment of gingival recession. METHODS:Eleven non-smoking subjects ...

    journal_title:Journal of periodontology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1902/jop.2004.75.3.413

    authors: da Silva RC,Joly JC,de Lima AF,Tatakis DN

    更新日期:2004-03-01 00:00:00

  • Association between periodontitis and gestational diabetes mellitus: a case-control study.

    abstract:BACKGROUND:Some studies have reported an association between gestational diabetes mellitus (GDM) and periodontitis. The aim of the present study is to analyze this potential association and the influence of risk variables associated with GDM. METHODS:This case-control study includes 360 women, 90 with GDM and 270 cont...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2012.120350

    authors: Esteves Lima RP,Miranda Cota LO,Costa FO

    更新日期:2013-09-01 00:00:00

  • The gene expression profile in refractory periodontitis patients.

    abstract:BACKGROUND:There are no specific bacterial profiles or diagnostic tests capable of identifying refractory periodontitis patients before a treatment regimen is initiated. Therefore, in this high-risk cohort of patients who do not respond appropriately, host factors that might be partly under genetic control may play a c...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2006.050254

    authors: Kim DM,Ramoni MF,Nevins M,Fiorellini JP

    更新日期:2006-06-01 00:00:00

  • A comparative study of root coverage obtained with guided tissue regeneration utilizing a bioabsorbable membrane versus the connective tissue with partial-thickness double pedicle graft.

    abstract::Obtaining predictable root coverage has become an important part of periodontal therapy. The purpose of this study was to compare two techniques of obtaining root coverage. The two techniques were the connective tissue with partial-thickness double pedicle graft and guided tissue regeneration with a bioabsorbable poly...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1997.68.8.779

    authors: Harris RJ

    更新日期:1997-08-01 00:00:00

  • Acute necrotizing ulcerative gingivitis. A transmission electron microscope study.

    abstract::The purpose of this study was to provide additional evidence that in the lesions of acute necrotizing ulcerative gingivitis (ANUG), spirochetes and other microorganisms are capable of invading the nonnecrotic lamina propria of affected gingivae. Biopsies from eight patients with pathognomonic signs of ANUG were obtain...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1983.54.11.671

    authors: Courtois GJ 3rd,Cobb CM,Killoy WJ

    更新日期:1983-11-01 00:00:00

  • Reliability of attachment level measurements using the cementoenamel junction and a plastic stent.

    abstract::Repeated measurements of attachment level appear to be important assessments in periodontal clinical trials, yet the lack of reliability for this assessment creates measurement error which in turn demands increased sample sizes or reduces the power of the test. A plastic occlusal stent has been developed as a fixed re...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1987.58.2.115

    authors: Clark DC,Chin Quee T,Bergeron MJ,Chan EC,Lautar-Lemay C,de Gruchy K

    更新日期:1987-02-01 00:00:00

  • Lifestyle and psychosocial factors associated with chronic periodontitis in Taiwanese adults.

    abstract:BACKGROUND:The development of chronic periodontitis (CP) is a multifactorial process and variation in severity cannot be explained by just a few risk factors. The aims of this study were: 1) to explore the lifestyle and psychosocial factors of CP patients and 2) to estimate the proportion of total CP cases attributable...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2003.74.8.1169

    authors: Teng HC,Lee CH,Hung HC,Tsai CC,Chang YY,Yang YH,Lu CT,Yen YY,Wu YM

    更新日期:2003-08-01 00:00:00

  • Subgingival microflora of advanced periodontitis in the Dominican Republic.

    abstract::A study of the predominant subgingival microflora was carried out in 24 periodontitis patients, 18 to 60 years of age, in Santo Domingo, Dominican Republic. Paper point sampling, transport in VMGA III, and conventional microbiological techniques were utilized. Direct microscopic examination revealed that cocci and non...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1991.62.9.543

    authors: Slots J,Rams TE,Feik D,Taveras HD,Gillespie GM

    更新日期:1991-09-01 00:00:00

  • Coronally advanced flap procedure for root coverage. Treatment of root surface: root planning versus polishing.

    abstract::This clinical study was designed to determine if mechanical instrumentation (root planing) of the exposed root is useful in treating gingival recession caused by traumatic toothbrushing following a coronally advanced flap (CAF). Ten patients with high levels of oral hygiene (full-mouth plaque score <20%), from 25 to 5...

    journal_title:Journal of periodontology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1902/jop.1999.70.9.1064

    authors: Pini-Prato G,Baldi C,Pagliaro U,Nieri M,Saletta D,Rotundo R,Cortellini P

    更新日期:1999-09-01 00:00:00

  • The reliability of a colorimetric test in determining gingival inflammation.

    abstract::This investigation was undertaken to compare the Gindex saliva test scores with the Gingival Index scores and crevicular fluid flow scores, as proposed by Löe and Holm-Pedersen. Eighty-one patients were tested using the Gindex chemical analysis kit. Crevicular fluid was collected from the six teeth advocated by Ramfjo...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1978.49.11.564

    authors: Abbott BH,Caffesse RG

    更新日期:1978-11-01 00:00:00

  • Local delivery of hyaluronan as an adjunct to scaling and root planing in the treatment of chronic periodontitis.

    abstract:BACKGROUND:The aim of the present study was to evaluate the adjunctive effect of the local application of a hyaluronan gel to scaling and root planing in the treatment of chronic periodontitis. METHODS:Twelve patients with chronic periodontitis were recruited to participate in a study with a split-mouth design and pro...

    journal_title:Journal of periodontology

    pub_type: 杂志文章,随机对照试验

    doi:10.1902/jop.2009.090128

    authors: Johannsen A,Tellefsen M,Wikesjö U,Johannsen G

    更新日期:2009-09-01 00:00:00

  • Periodontal surgery for a patient with paroxysmal nocturnal hemoglobinuria.

    abstract::Paroxysmal nocturnal hemoglobinuria (PNH) is an uncommon blood stem cell disorder. The acquired defect is in the cell membrane of the precursor of the affected clone, which renders erythrocytes, platelets and granulocytes unusually sensitive to the hemolytic effects of complement. It is characterized by chronic hemoly...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1988.59.2.115

    authors: Cohen CI,Zimmerman DR

    更新日期:1988-02-01 00:00:00

  • Scanning electron microscopic observations of cell populations and bacterial contamination of membranes used for guided periodontal tissue regeneration in humans.

    abstract::Fourteen intrabony periodontal defects and six furcation defects (Class II) were treated by a flap procedure which included the use of a polytetrafluoroethylene membrane to allow guided tissue regeneration. After 4 to 6 weeks of healing, the membranes were retrieved and examined by scanning electron microscopy for the...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1990.61.8.515

    authors: Selvig KA,Nilveus RE,Fitzmorris L,Kersten B,Khorsandi SS

    更新日期:1990-08-01 00:00:00

  • A critical review of the biologic rationale for guided tissue regeneration.

    abstract::This review discusses the rationale for using guided tissue regeneration therapy. The review not only attempts to clarify the concept of selective tissue regeneration using non-resorbable and resorbable barriers, but to discuss differences in healing events after treatment with the two types of barriers together with ...

    journal_title:Journal of periodontology

    pub_type: 杂志文章,meta分析

    doi:10.1902/jop.1991.62.3.171

    authors: Minabe M

    更新日期:1991-03-01 00:00:00

  • Effects of plaque control on the patency of dentinal tubules: an in vivo study in beagle dogs.

    abstract:BACKGROUND:The aim of this in vivo study was to evaluate the effects of plaque control on the patency of dentinal tubules using vital teeth of beagle dogs. METHODS:Class V cavities were prepared on the cervical areas of the mandibular and maxillary molars in each dog with a diamond point. To simulate the state of dent...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2006.050159

    authors: Suge T,Kawasaki A,Ishikawa K,Matsuo T,Ebisu S

    更新日期:2006-03-01 00:00:00

  • Resolution of inflammation in periodontitis.

    abstract::Chronic inflammatory illnesses such as diabetes, arthritis, and heart disease are now seen as problems that might have impacts on the periodontium, and reciprocal effects of periodontal diseases are being considered as factors potentially affecting the progression of these diseases. Successful management of the inflam...

    journal_title:Journal of periodontology

    pub_type: 杂志文章,评审

    doi:10.1902/jop.2005.76.11-S.2168

    authors: Kantarci A,Van Dyke TE

    更新日期:2005-11-01 00:00:00

  • Porphyromonas gingivalis Lipopolysaccharide Stimulation of Vascular Smooth Muscle Cells Activates Proliferation and Calcification.

    abstract:BACKGROUND:Porphyromonas gingivalis (Pg) is a major etiologic agent of periodontitis, whose virulence has been attributed to different factors, including lipopolysaccharide (LPS). Vascular ectopic calcification as a well-known major risk factor for adverse cardiovascular diseases is a highly prevalent vascular pathophe...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2016.150602

    authors: Liu G,Deng J,Zhang Q,Song W,Chen S,Lou X,Zhang P,Pan K

    更新日期:2016-07-01 00:00:00

  • Clinical guidelines of the Italian Society of Periodontology for the reconstructive surgical treatment of angular bony defects in periodontal patients.

    abstract:BACKGROUND:The purpose of these clinical guidelines, commissioned by the Italian Society of Periodontology and compiled with the tools and instructions of the Appraisal of Guidelines for Research and Evaluation (AGREE) collaboration, was to determine, in terms of efficacy, complications, and patient opinions, the most ...

    journal_title:Journal of periodontology

    pub_type: 杂志文章,实务指引

    doi:10.1902/jop.2008.080266

    authors: Pagliaro U,Nieri M,Rotundo R,Cairo F,Carnevale G,Esposito M,Cortellini P,Pini-Prato G,Italian Society of Periodontology.

    更新日期:2008-12-01 00:00:00