Abstract:
BACKGROUND:Pain generated by needle sticks (Ns) for the delivery of local anesthetic and/or scaling and root planing (SRP) instrumentation is commonly addressed by the use of topical anesthetics, such as a benzocaine-gel preparation (BGP). Pain suppression following such use has been highly variable. Development of medicine-containing patches and adhesives for intraoral use have led to a new approach for topical anesthesia in the form of a transoral lidocaine delivery system (LDS). The purpose of this double-blind study was to evaluate the efficacy of the LDS and also to compare LDS with BGP for pain suppression to Ns and SRP. METHODS:One group of 20 subjects randomly received in both maxillary and mandibular molar-bicuspid areas LDS or BGP on one side and non-anesthetic control on the other side. A second group of 20 subjects compared the effectiveness of LDS directly with BGP in molar-bicuspid areas of both arches. Random order determined the selection for each anesthetic tested between the arches and bilateral. Pain perception was separately scored to a pain-inducing Ns simulation without anesthetic injection at each area and subsequently also to SRP using both a verbal pain scale (VPS) and a visual analog scale (VAS). RESULTS:VPS and VAS results analyzed by Bonferroni-adjusted Wilcoxon matched-pairs signed-rank tests found pain suppression scores significantly (P < 0.005) reduced for Ns by LDS to controls and to BGP. Comparing LDS directly with BGP, LDS was significantly (P < 0.05) more effective in reducing pain to Ns in both arches, to SRP in the maxillary arch, and equally effective as BGP in the mandibular arch. CONCLUSIONS:LDS is more effective than BGP for topical pain suppression to Ns and SRP in both arches.
journal_name
J Periodontoljournal_title
Journal of periodontologyauthors
Carr MP,Horton JEdoi
10.1902/jop.2001.72.4.479subject
Has Abstractpub_date
2001-04-01 00:00:00pages
479-84issue
4eissn
0022-3492issn
1943-3670journal_volume
72pub_type
临床试验,杂志文章,随机对照试验abstract::The authors review patient-reported outcome (PRO) metrics for dentistry, and in particular, periodontics. The PRO commentary for periodontics includes a review of split-mouth, randomized, controlled clinical trial results that specifically tracked pain at different sites over time after intervention and provided guide...
journal_title:Journal of periodontology
pub_type: 杂志文章,评审
doi:10.1902/jop.2014.130693
更新日期:2014-10-01 00:00:00
abstract:BACKGROUND:Crohn's disease is a chronic inflammatory bowel disease characterized by uncertainty in etiology and pathogenesis occasionally with manifestations in oral mucous membranes. This report reviews the literature on Crohn's disease and presents a patient with Crohn's disease on continuous anti-inflammatory and im...
journal_title:Journal of periodontology
pub_type: 杂志文章,评审
doi:10.1902/jop.2003.74.4.537
更新日期:2003-04-01 00:00:00
abstract:BACKGROUND:Desipramine is a tricyclic antidepressant with immune-modulatory activity, whose effects on ligature-induced periodontitis are yet to be investigated. Hence, its actions on alveolar bone resorption, gingival collagen content and key inflammatory mediators were herewith analyzed. METHODS:A total of 60 male W...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1002/JPER.19-0569
更新日期:2020-12-01 00:00:00
abstract::The research reviewed in this paper constitutes a series of investigations intended to develop and evaluate a new membrane technique, which provides improved conditions for osteogenesis during healing of bone defects and restitution of earlier existing bone. The technique has also been shown to aid in bone grafting as...
journal_title:Journal of periodontology
pub_type: 杂志文章,评审
doi:10.1902/jop.1993.64.11s.1116
更新日期:1993-11-01 00:00:00
abstract:BACKGROUND:An experimental periodontal sensor probe (SP) equipped with an optical fiber for recording function was developed. The aim was to test the intraexaminer reproducibility of probing using the SP and to assess the consistency with the manual probe (MP). METHODS:The SP was assembled with an external sheath cove...
journal_title:Journal of periodontology
pub_type: 杂志文章,随机对照试验
doi:10.1902/jop.2011.110047
更新日期:2012-02-01 00:00:00
abstract:BACKGROUND:Multiple factors that influence the precision of periodontal probing measurements have been identified. These factors can be categorized as being dependent upon host-related, probe-related, or examiner-related variables. However, the potential influence of examiner handedness (right or left) on the measureme...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2006.050185
更新日期:2006-07-01 00:00:00
abstract:BACKGROUND:Chronic exposure to occupational noise is reported to cause a wide range of health problems. But, there are no reports on studies investigating the association between noise exposure and periodontitis. The purpose of this study was to examine the relationship between occupational noise exposure and periodont...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1002/JPER.17-0484
更新日期:2018-04-01 00:00:00
abstract:BACKGROUND:Clinical and radiographic measures are gold standards for diagnosing periodontitis but offer little information regarding the pathogenesis of the disease. We hypothesized that a comparison of gene expression signatures between healthy and diseased gingival tissues would provide novel insights in the pathobio...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2008.080139
更新日期:2008-11-01 00:00:00
abstract::The purpose of this histologic, histometric, and autoradiographic study was to examine the effect of citric acid conditioning and lyophilized autologous plasma (LAP) application on healing following periodontal flap surgery. Mucoperiosteal flaps were elevated in six rhesus monkeys using the modified Widman flap proced...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1987.58.11.770
更新日期:1987-11-01 00:00:00
abstract::Dental implant placement associated with augmentation of the sinus floor in the severely atrophic maxilla can be performed in 1- or 2-surgical stages, depending on the height of the residual alveolar bone. A minimum of 4 to 5 mm of residual alveolar bone height is recommended for a 1-stage surgical procedure. The pres...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1998.69.12.1397
更新日期:1998-12-01 00:00:00
abstract:BACKGROUND:It has been suggested that cyclosporine A (CsA) induces gingival enlargement by promoting an increase in the gingival extracellular matrix (ECM). Nonetheless, the variable occurrence of CsA-induced gingival enlargement in patients receiving this medication indicates a multifactorial pathogenesis. Clinical ob...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2012.120224
更新日期:2013-05-01 00:00:00
abstract:BACKGROUND:This study compares the levels of cytokines and bone-related factors in the gingival crevicular fluid (GCF) of systemically healthy patients with chronic periodontitis (CP); and better-controlled, and poorly controlled patients with type 2 diabetes and CP. METHODS:Thirty-seven patients with type 2 diabetes ...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2011.100643
更新日期:2011-08-01 00:00:00
abstract:BACKGROUND:Various surgical techniques have been proposed for treating gingival recession. This randomized clinical trial compared the coronally positioned flap (CPF) alone or in conjunction with a subepithelial connective tissue graft (SCTG) in the treatment of gingival recession. METHODS:Eleven non-smoking subjects ...
journal_title:Journal of periodontology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1902/jop.2004.75.3.413
更新日期:2004-03-01 00:00:00
abstract:BACKGROUND:Some studies have reported an association between gestational diabetes mellitus (GDM) and periodontitis. The aim of the present study is to analyze this potential association and the influence of risk variables associated with GDM. METHODS:This case-control study includes 360 women, 90 with GDM and 270 cont...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2012.120350
更新日期:2013-09-01 00:00:00
abstract:BACKGROUND:There are no specific bacterial profiles or diagnostic tests capable of identifying refractory periodontitis patients before a treatment regimen is initiated. Therefore, in this high-risk cohort of patients who do not respond appropriately, host factors that might be partly under genetic control may play a c...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2006.050254
更新日期:2006-06-01 00:00:00
abstract::Obtaining predictable root coverage has become an important part of periodontal therapy. The purpose of this study was to compare two techniques of obtaining root coverage. The two techniques were the connective tissue with partial-thickness double pedicle graft and guided tissue regeneration with a bioabsorbable poly...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1997.68.8.779
更新日期:1997-08-01 00:00:00
abstract::The purpose of this study was to provide additional evidence that in the lesions of acute necrotizing ulcerative gingivitis (ANUG), spirochetes and other microorganisms are capable of invading the nonnecrotic lamina propria of affected gingivae. Biopsies from eight patients with pathognomonic signs of ANUG were obtain...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1983.54.11.671
更新日期:1983-11-01 00:00:00
abstract::Repeated measurements of attachment level appear to be important assessments in periodontal clinical trials, yet the lack of reliability for this assessment creates measurement error which in turn demands increased sample sizes or reduces the power of the test. A plastic occlusal stent has been developed as a fixed re...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1987.58.2.115
更新日期:1987-02-01 00:00:00
abstract:BACKGROUND:The development of chronic periodontitis (CP) is a multifactorial process and variation in severity cannot be explained by just a few risk factors. The aims of this study were: 1) to explore the lifestyle and psychosocial factors of CP patients and 2) to estimate the proportion of total CP cases attributable...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2003.74.8.1169
更新日期:2003-08-01 00:00:00
abstract::A study of the predominant subgingival microflora was carried out in 24 periodontitis patients, 18 to 60 years of age, in Santo Domingo, Dominican Republic. Paper point sampling, transport in VMGA III, and conventional microbiological techniques were utilized. Direct microscopic examination revealed that cocci and non...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1991.62.9.543
更新日期:1991-09-01 00:00:00
abstract::This clinical study was designed to determine if mechanical instrumentation (root planing) of the exposed root is useful in treating gingival recession caused by traumatic toothbrushing following a coronally advanced flap (CAF). Ten patients with high levels of oral hygiene (full-mouth plaque score <20%), from 25 to 5...
journal_title:Journal of periodontology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1902/jop.1999.70.9.1064
更新日期:1999-09-01 00:00:00
abstract::This investigation was undertaken to compare the Gindex saliva test scores with the Gingival Index scores and crevicular fluid flow scores, as proposed by Löe and Holm-Pedersen. Eighty-one patients were tested using the Gindex chemical analysis kit. Crevicular fluid was collected from the six teeth advocated by Ramfjo...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1978.49.11.564
更新日期:1978-11-01 00:00:00
abstract:BACKGROUND:The aim of the present study was to evaluate the adjunctive effect of the local application of a hyaluronan gel to scaling and root planing in the treatment of chronic periodontitis. METHODS:Twelve patients with chronic periodontitis were recruited to participate in a study with a split-mouth design and pro...
journal_title:Journal of periodontology
pub_type: 杂志文章,随机对照试验
doi:10.1902/jop.2009.090128
更新日期:2009-09-01 00:00:00
abstract::Paroxysmal nocturnal hemoglobinuria (PNH) is an uncommon blood stem cell disorder. The acquired defect is in the cell membrane of the precursor of the affected clone, which renders erythrocytes, platelets and granulocytes unusually sensitive to the hemolytic effects of complement. It is characterized by chronic hemoly...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1988.59.2.115
更新日期:1988-02-01 00:00:00
abstract::Fourteen intrabony periodontal defects and six furcation defects (Class II) were treated by a flap procedure which included the use of a polytetrafluoroethylene membrane to allow guided tissue regeneration. After 4 to 6 weeks of healing, the membranes were retrieved and examined by scanning electron microscopy for the...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1990.61.8.515
更新日期:1990-08-01 00:00:00
abstract::This review discusses the rationale for using guided tissue regeneration therapy. The review not only attempts to clarify the concept of selective tissue regeneration using non-resorbable and resorbable barriers, but to discuss differences in healing events after treatment with the two types of barriers together with ...
journal_title:Journal of periodontology
pub_type: 杂志文章,meta分析
doi:10.1902/jop.1991.62.3.171
更新日期:1991-03-01 00:00:00
abstract:BACKGROUND:The aim of this in vivo study was to evaluate the effects of plaque control on the patency of dentinal tubules using vital teeth of beagle dogs. METHODS:Class V cavities were prepared on the cervical areas of the mandibular and maxillary molars in each dog with a diamond point. To simulate the state of dent...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2006.050159
更新日期:2006-03-01 00:00:00
abstract::Chronic inflammatory illnesses such as diabetes, arthritis, and heart disease are now seen as problems that might have impacts on the periodontium, and reciprocal effects of periodontal diseases are being considered as factors potentially affecting the progression of these diseases. Successful management of the inflam...
journal_title:Journal of periodontology
pub_type: 杂志文章,评审
doi:10.1902/jop.2005.76.11-S.2168
更新日期:2005-11-01 00:00:00
abstract:BACKGROUND:Porphyromonas gingivalis (Pg) is a major etiologic agent of periodontitis, whose virulence has been attributed to different factors, including lipopolysaccharide (LPS). Vascular ectopic calcification as a well-known major risk factor for adverse cardiovascular diseases is a highly prevalent vascular pathophe...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2016.150602
更新日期:2016-07-01 00:00:00
abstract:BACKGROUND:The purpose of these clinical guidelines, commissioned by the Italian Society of Periodontology and compiled with the tools and instructions of the Appraisal of Guidelines for Research and Evaluation (AGREE) collaboration, was to determine, in terms of efficacy, complications, and patient opinions, the most ...
journal_title:Journal of periodontology
pub_type: 杂志文章,实务指引
doi:10.1902/jop.2008.080266
更新日期:2008-12-01 00:00:00