Long-term results of guided tissue regeneration therapy with non-resorbable and bioabsorbable barriers. IV. A case series of infrabony defects after 10 years.

Abstract:

BACKGROUND:A 10-year follow-up study was conducted to clinically evaluate the long-term results after guided tissue regeneration (GTR) therapy of infrabony defects using non-resorbable and bioabsorbable barriers. METHODS:Twelve pairs of contralateral infrabony defects were treated in 12 subjects with advanced periodontitis. Within each subject, one defect received a non-resorbable barrier and the other received a bioabsorbable barrier by random assignment. Clinical parameters were obtained at baseline and at 12 and 120+/-6 months after surgery. RESULTS:Eight of 12 subjects were available for the examination at 120+/-6 months. Twelve and 120+/-6 months after GTR therapy statistically significant (P<0.05) vertical clinical attachment level (CAL-V) gain was observed in both groups (3.4+/-1.0 mm and 1.5+/-1.2 mm for the control group at 12 and 120 months, respectively, and 3.3+/-1.6 mm and 3.5+/-2.5 mm for the test group at 12 and 120 months, respectively). However, 120+/-6 months after GTR therapy, three infrabony defects (two controls and one test) had lost >2 mm of the attachment that had been gained 12 months after GTR therapy, and a statistically significant mean CAL-V loss of 1.7+/-1.3 mm was observed from 12 to 120+/-6 months in the control group. One tooth in the control group was lost between 60 and 120+/-6 months. The case series failed to show statistically significant differences between test and control regarding CAL-V gain 120+/-6 months after surgery. CONCLUSION:CAL-V gain achieved 12 months after GTR therapy in infrabony defects using non-resorbable and bioabsorbable barriers was stable after 10 years in 12 of 16 defects.

journal_name

J Periodontol

authors

Pretzl B,Kim TS,Holle R,Eickholz P

doi

10.1902/jop.2008.070571

subject

Has Abstract

pub_date

2008-08-01 00:00:00

pages

1491-9

issue

8

eissn

0022-3492

issn

1943-3670

journal_volume

79

pub_type

杂志文章,随机对照试验
  • Acceptance Program Guidelines. Products designed to regenerate periodontal tissues. Council on Scientific Affairs. American Dental Association.

    abstract:SCOPE:These Guidelines apply to products used to promote the regeneration of periodontal tissues lost due to periodontal diseases or other causes. Periodontal regeneration is defined histologically as regeneration of the tooth's supporting tissues, including alveolar bone, periodontal ligament, and cementum over a prev...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1998.69.9.1081

    authors:

    更新日期:1998-09-01 00:00:00

  • Ovariectomy and timing of impaired maxillary alveolar bone regeneration: An experimental study in rats.

    abstract:BACKGROUND:The aim of this study was to seek the critical time for impairment of alveolar bone regeneration after ovariectomy (OVX) in rats. METHODS:A total of 32 female rats were used. Test group rats were divided into a 2M group (n = 8), a 3M group (n = 8) and a 4M group (n = 8) according to the duration from OVX to...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1002/JPER.19-0537

    authors: Kim HJ,Kim KH,Lee YM,Ku Y,Heo SJ,Rhyu IC,Seol YJ

    更新日期:2020-10-01 00:00:00

  • Sex differences in inflammatory and apoptotic signaling molecules in normal and diseased human gingiva.

    abstract:BACKGROUND:The purpose of this study is to determine whether sex dimorphism exists in the expression of inflammatory and apoptotic mediators in gingiva obtained from normal and diseased sites of periodontal disease. METHODS:Gingival papillae were obtained from individuals (56 males and 62 females) who required extract...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2014.130718

    authors: Johnson RB,Wikle JC

    更新日期:2014-11-01 00:00:00

  • Detection of local and systemic cytokines in adult periodontitis.

    abstract::Periodontitis is a chronic inflammatory disease of the soft and hard supporting tissues of the teeth and is a major cause of tooth loss in adults. The local host response to periodontopathic bacteria results in the release of inflammatory mediators and cytokines. Since cytokines are indicative of effector functions, w...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1996.67.5.515

    authors: Prabhu A,Michalowicz BS,Mathur A

    更新日期:1996-05-01 00:00:00

  • Some anatomical factors related to furcation involvements.

    abstract::A total of 305 dry human skull specimens were examined for the presence of furcation involvements. Of a total of 188 furcation involvements, 142 (75%) were related to the close proximity of the furcation to the cemento enamel junction of the tooth. ...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1975.46.10.608

    authors: Larato DC

    更新日期:1975-10-01 00:00:00

  • Adsorption of enamel matrix proteins to a bovine-derived bone grafting material and its regulation of cell adhesion, proliferation, and differentiation.

    abstract:BACKGROUND:The use of various combinations of enamel matrix derivative (EMD) and grafting materials has been shown to promote periodontal wound healing/regeneration. However, the downstream cellular behavior of periodontal ligament (PDL) cells and osteoblasts has not yet been studied. Furthermore, it is unknown to what...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2011.110480

    authors: Miron RJ,Bosshardt DD,Hedbom E,Zhang Y,Haenni B,Buser D,Sculean A

    更新日期:2012-07-01 00:00:00

  • Removal torque and histomorphometric evaluation of bioceramic grit-blasted/acid-etched and dual acid-etched implant surfaces: an experimental study in dogs.

    abstract:BACKGROUND:Surface modifications to dental implants have been used in an attempt to accelerate the osseointegration process. The objective of this study was to biomechanically/histomorphometrically evaluate a bioceramic grit-blasted and acid-etched surface (BGB/AA; test) versus a dual acid-etched implant surface (contr...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2008.080106

    authors: Marin C,Granato R,Suzuki M,Gil JN,Piattelli A,Coelho PG

    更新日期:2008-10-01 00:00:00

  • Allogeneic iliac transplants in rhesus monkeys. A sequential histologic study.

    abstract::Fresh and frozen allogeneic iliac grafts were used in surgically prepared intraosseous defects. Four adult rhesus monkeys provided 19 specimens from 0 to 56 days postoperative. There were 8 specimens for each type of graft and 3 others used as controls. Histologic sections from each specimen were prepared and a descri...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1976.47.4.187

    authors: Poulsom RC,Rubinstein A,Gargiulo AW

    更新日期:1976-04-01 00:00:00

  • Clinical evaluation and comparison of 2 topical anesthetics for pain caused by needle sticks and scaling and root planing.

    abstract:BACKGROUND:Pain generated by needle sticks (Ns) for the delivery of local anesthetic and/or scaling and root planing (SRP) instrumentation is commonly addressed by the use of topical anesthetics, such as a benzocaine-gel preparation (BGP). Pain suppression following such use has been highly variable. Development of med...

    journal_title:Journal of periodontology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1902/jop.2001.72.4.479

    authors: Carr MP,Horton JE

    更新日期:2001-04-01 00:00:00

  • Non-Invasive Periodontal Probing Through Fourier-Domain Optical Coherence Tomography.

    abstract:BACKGROUND:Periodontitis is a multifactorial and infectious disease that may result in significant debilitation. The aim of this study is to exploit two optical coherence tomography (OCT) systems operating in the Fourier domain at different wavelengths, 930 and 1,325 nm, for structural analysis of periodontal tissue in...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2015.150047

    authors: Mota CC,Fernandes LO,Cimões R,Gomes AS

    更新日期:2015-09-01 00:00:00

  • A histological study on tissue responses to titanium implantation in rat maxilla: the process of epithelial regeneration and bone reaction.

    abstract::The present study aimed to establish a titanium implantation model using rat maxillae as well as demonstrate the chronological tissue responses to implantation. Pure titanium implants were inserted in the upper first molar extraction sites of Wistar rats 1 month after tooth extraction. The animals were sacrificed at 1...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1998.69.4.485

    authors: Fujii N,Kusakari H,Maeda T

    更新日期:1998-04-01 00:00:00

  • Periodontal assessment by right- and left-handed examiners: is there a difference?

    abstract:BACKGROUND:Multiple factors that influence the precision of periodontal probing measurements have been identified. These factors can be categorized as being dependent upon host-related, probe-related, or examiner-related variables. However, the potential influence of examiner handedness (right or left) on the measureme...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2006.050185

    authors: Khan SM,Blanchard SB,Dowsett SA,Eckert GJ,Kowolik MJ

    更新日期:2006-07-01 00:00:00

  • Levels of advanced glycation end products in gingival crevicular fluid of chronic periodontitis patients with and without type-2 diabetes mellitus.

    abstract:BACKGROUND:It is hypothesized that levels of advanced glycation end products (AGEs) are higher in the gingival crevicular fluid (GCF) of chronic periodontitis (CP) patients with type-2 diabetes mellitus (type-2 DM) than controls (systemically healthy individuals without CP. The aim was to assess the levels of AGEs in t...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1002/JPER.19-0209

    authors: Akram Z,Alqahtani F,Alqahtani M,Al-Kheraif AA,Javed F

    更新日期:2020-03-01 00:00:00

  • Association of plasma 25-hydroxyvitamin d concentrations and pathogenic oral bacteria in postmenopausal females.

    abstract:BACKGROUND:Previous findings of an association between 25-hydroxyvitamin D [25(OH)D] concentrations and periodontal disease may be partially explained by the antimicrobial properties of vitamin D. To the best of the authors' knowledge, no study has investigated the association between 25(OH)D and pathogenic oral bacter...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2013.130518

    authors: Sahli MW,Wactawski-Wende J,Ram PK,LaMonte MJ,Hovey KM,Genco RJ,Andrews CA,Millen AE

    更新日期:2014-07-01 00:00:00

  • Bone demineralization with citric acid enhances adhesion and spreading of preosteoblasts.

    abstract:BACKGROUND:Previous studies have demonstrated that bone demineralization can improve consolidation in bone grafts. The biologic mechanisms underlying this phenomenon remain unclear. METHODS:Twelve adult male guinea pigs were used in this experiment. Forty-five bone samples removed from the calvaria of nine animals wer...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2014.130657

    authors: de Rezende ML,Coesta PT,de Oliveira RC,Salmeron S,Sant'Ana AC,Damante CA,Greghi SL,Consolaro A

    更新日期:2015-01-01 00:00:00

  • Partial regeneration of periodontal tissues using collagen barriers. Initial observations in the canine.

    abstract::The capacity of collagen membranes to support guided regeneration of periodontal tissues in the dog was assessed. The mesiolabial, labial and distolabial aspects of the mesial root of the second and third mandibular premolar were surgically exposed in three beagle dogs. Collagen membranes, 0.5 to 0.7 mm thick, prepare...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1988.59.6.380

    authors: Pitaru S,Tal H,Soldinger M,Grosskopf A,Noff M

    更新日期:1988-06-01 00:00:00

  • Collagen formation at the tooth-cell interface: comparative ultrastructural study on the effect of partial demineralization of cementum with dentin.

    abstract::In order to compare the effect of partial demineralization with root planing and partial demineralization of cementum with that of dentin on healing, the ultrastructural morphology of the interface between the layer of human periodontal ligament-derived, fibroblast-like cells (HPF) and the treated root surface was stu...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1995.66.4.267

    authors: Higashi T,Onzuka T,Satoh G,Yoshino H,Okamoto H

    更新日期:1995-04-01 00:00:00

  • Puberty gingivitis in insulin-dependent diabetic children. I. Cross-sectional observations.

    abstract::This cross-sectional study examined the gingivitis occurring at puberty in a population of insulin-dependent juvenile diabetics. Seventy-seven children between the ages of 6 and 15 years were examined for gingivitis levels, stages of pubertal maturation and blood levels of glucose and glycosylated hemoglobin. Bacteria...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1983.54.12.714

    authors: Gusberti FA,Syed SA,Bacon G,Grossman N,Loesche WJ

    更新日期:1983-12-01 00:00:00

  • Levels of pentraxin-3 in gingival crevicular fluid and plasma in periodontal health and disease.

    abstract:BACKGROUND:Pentraxins are classic mediators of inflammation and markers of acute-phase reactions. Pentraxin-3 (PTX3) is the first-identified long pentraxin and is believed to be a true independent indicator of disease activity. Although a classic pentraxin, C-reactive protein, and its association with various systemic ...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2010.100526

    authors: Pradeep AR,Kathariya R,Raghavendra NM,Sharma A

    更新日期:2011-05-01 00:00:00

  • Number of teeth is related to atherosclerotic plaque in the carotid arteries in an elderly population.

    abstract:BACKGROUND:Periodontal disease has been associated with cardiovascular disorders with an atherosclerotic background, and number of teeth (NT) has been suggested as a possible risk indicator for cardiovascular disease. The objective of this study is to investigate whether NT was related to the intima-media thickness (IM...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2011.110100

    authors: Holmlund A,Lind L

    更新日期:2012-03-01 00:00:00

  • Repair of Class II furcation defects after a reparative tissue graft obtained from extraction sockets treated with growth factors: a histologic and histometric study in dogs.

    abstract:BACKGROUND:Reparative tissue of extraction sockets was proposed as grafting material in the treatment of periodontal defects. Our hypothesis was that the addition of growth factors to extraction sockets improves the regenerative potential of this tissue when used as a graft. The objective of the present study was to an...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2005.76.10.1681

    authors: Soares FP,Hayashi F,Yorioka CW,Pannuti CM,Gioso MA,de Lima LA,Romito GA,Pustiglioni FE

    更新日期:2005-10-01 00:00:00

  • Periodontal findings in adult twins.

    abstract::Gingivitis and periodontitis are among the most common diseases known to man. Although bacterial plaque is generally accepted as the primary etiologic agent, little information is available concerning the influence that host genetic factors have on these diseases. The purpose of the present study was to examine the re...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1991.62.5.293

    authors: Michalowicz BS,Aeppli D,Virag JG,Klump DG,Hinrichs JE,Segal NL,Bouchard TJ Jr,Pihlstrom BL

    更新日期:1991-05-01 00:00:00

  • The effect of periodontal treatment on serum leptin, interleukin-6, and C-reactive protein.

    abstract:BACKGROUND:Previous studies suggest that periodontitis is closely related to obesity and metabolic syndrome. Leptin, a pleiotrophic hormone produced by adipose tissue, has been reported to be related to periodontitis. This study investigates the effects of periodontal treatment on the serum levels of leptin and other c...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2010.090741

    authors: Shimada Y,Komatsu Y,Ikezawa-Suzuki I,Tai H,Sugita N,Yoshie H

    更新日期:2010-08-01 00:00:00

  • Effect of cigarette smoke inhalation and estrogen deficiency on bone healing around titanium implants: a histometric study in rats.

    abstract:BACKGROUND:It has been shown that cigarette smoke inhalation (CSI) and estrogen deficiency (OVX) may affect bone quality around titanium implants; however, their association has not been evaluated. Therefore, this study aimed to verify the effects of CSI associated with OVX on bone healing around titanium implants. ME...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2006.050190

    authors: Carvalho MD,Benatti BB,César-Neto JB,Nociti FH Jr,da Rocha Nogueira Filho G,Casati MZ,Sallum EA

    更新日期:2006-04-01 00:00:00

  • The effect of platelet-rich plasma on the coronally advanced flap root coverage procedure: a pilot human trial.

    abstract:BACKGROUND:Coronally advanced flap (CAF) has been shown to effectively treat gingival recession. Platelet-rich plasma (PRP), containing autologous growth factors, has been shown to promote soft tissue healing. Therefore, the purpose of this study was to evaluate the effects of PRP in combination with CAF. METHODS:Twen...

    journal_title:Journal of periodontology

    pub_type: 杂志文章,随机对照试验

    doi:10.1902/jop.2005.76.10.1768

    authors: Huang LH,Neiva RE,Soehren SE,Giannobile WV,Wang HL

    更新日期:2005-10-01 00:00:00

  • Effect of periodontal therapy on patients maintained for 15 years or longer. A retrospective study.

    abstract::A retrospective study of tooth loss in 211 patients who were treated for periodontal disease in private practice and maintained for 15 to 34 years on 3- to 6-month recall schedules is reported. The average age of the patients was 42 years, and the average length of time in maintenance was 22 years. On the basis of res...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1986.57.6.347

    authors: Goldman MJ,Ross IF,Goteiner D

    更新日期:1986-06-01 00:00:00

  • Effect of recombinant human bone morphogenetic protein 2 associated with a variety of bone substitutes on vertical guided bone regeneration in rabbit calvarium.

    abstract:BACKGROUND:A major challenge for dental implantology is to consistently obtain appropriate bone augmentation before implant placement. The aim of this study is to evaluate the effect of recombinant human bone morphogenetic protein 2 (rhBMP-2) associated with bone substitute materials beta-tricalcium phosphate (β-TCP), ...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2012.110674

    authors: Polo CI,Lima JL,De Lucca L,Piacezzi CB,Naclério-Homem Mda G,Arana-Chavez VE,Sendyk WR

    更新日期:2013-03-01 00:00:00

  • Calprotectin and lactoferrin levels in the gingival crevicular fluid of children.

    abstract::The purpose of this study was to determine the levels of calprotectin and lactoferrin, 2 microbiostatic proteins, in the gingival crevicular fluid (GCF) of normal children. The children represented a population, primarily underprivileged, seeking care at a regional dental health care center. GCF was collected from Ram...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1998.69.8.879

    authors: Miyasaki KT,Voganatsi A,Huynh T,Marcus M,Underwood S

    更新日期:1998-08-01 00:00:00

  • Evaluation of the immunogenicity of freeze-dried skin allografts in humans.

    abstract::A study was undertaken to evaluate the antigenic potential of allogeneic freeze-dried skin (FDS) when used as a grafting material and to examine the clinical results when FDS is used for the correction of mucogingival problems in humans. FDS was obtained from an HLA-tissue-type donor according to Navy Tissue Bank prot...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1980.51.10.571

    authors: Gher ME Jr,Williams JE Jr,Vernino AR,Strong DM,Pelleu GB Jr

    更新日期:1980-10-01 00:00:00

  • Effects of hydrogen peroxide on oral carcinogenesis in hamsters.

    abstract::The effects of twice weekly topical applications of hydrogen peroxide on the buccal epithelium of Syrian hamsters were studied. Animals were treated either with hydrogen peroxide alone, with hydrogen peroxide and the carcinogen 9, 10-dimethyl-1,2-benzanthracene (DMBA), or with DMBA alone. In animals treated with 30% H...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1986.57.11.685

    authors: Weitzman SA,Weitberg AB,Stossel TP,Schwartz J,Shklar G

    更新日期:1986-11-01 00:00:00