Imaging placental function: current technology, clinical needs, and emerging modalities.

Abstract:

:The function of the placenta is challenging to characterize and as a result is understudied, despite the growing awareness of the impact of the placental environment on human health and development. Medical imaging has the potential to improve our ability to screen for diseases associated with placental insufficiency, and improve the monitoring and treatment of complex obstetric patients. This review provides an overview of clinical and preclinical imaging modalities currently available for assessing placental function, with an emphasis on emerging preclinical imaging modalities; as a group, these emerging modalities provide exceptional contrast and sensitivity for multimodal functional and molecular imaging of the placenta. Analysis of the successes and failures of medical imaging thus far provides guidance for the research community seeking to develop new imaging systems to assess placental function.

journal_name

Phys Med Biol

authors

Wu C,Bayer CL

doi

10.1088/1361-6560/aaccd9

subject

Has Abstract

pub_date

2018-07-09 00:00:00

pages

14TR01

issue

14

eissn

0031-9155

issn

1361-6560

journal_volume

63

pub_type

杂志文章,评审
  • A new method of body habitus correction for total body potassium measurements.

    abstract::This paper describes an accurate and time-efficient method for the determination of total body potassium via a combination of measurements in the Birmingham whole body counter and the use of the Monte Carlo n-particle (MCNP) simulation code. In developing this method, MCNP has also been used to derive values for some ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/51/17/009

    authors: O'Hehir S,Green S,Beddoe AH

    更新日期:2006-09-07 00:00:00

  • Staging of cervical cancer based on tumor heterogeneity characterized by texture features on (18)F-FDG PET images.

    abstract::The aim of the study is to assess the staging value of the tumor heterogeneity characterized by texture features and other commonly used semi-quantitative indices extracted from (18)F-FDG PET images of cervical cancer (CC) patients. Forty-two patients suffering CC at different stages were enrolled in this study. First...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/60/13/5123

    authors: Mu W,Chen Z,Liang Y,Shen W,Yang F,Dai R,Wu N,Tian J

    更新日期:2015-07-07 00:00:00

  • The impact of tracking system properties on the most likely path estimation in proton CT.

    abstract::Proton CT nowadays aims at improving hadron therapy treatment planning by mapping the stopping power of materials. In order to optimize a spatial resolution of the reconstructed images, the most likely path (MLP) of each proton can be computed. We investigated the errors in the computation of this path due to the conf...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/59/23/N197

    authors: Bopp C,Rescigno R,Rousseau M,Brasse D

    更新日期:2014-12-07 00:00:00

  • Three-dimensional optical tomography of the premature infant brain.

    abstract::For the first time, three-dimensional images of the newborn infant brain have been generated using measurements of transmitted light. A 32-channel time-resolved imaging system was employed, and data were acquired using custom-made helmets which couple source fibres and detector bundles to the infant head. Images have ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/47/23/303

    authors: Hebden JC,Gibson A,Yusof RM,Everdell N,Hillman EM,Delpy DT,Arridge SR,Austin T,Meek JH,Wyatt JS

    更新日期:2002-12-07 00:00:00

  • Comment on 'Proton beam monitor chamber calibration'.

    abstract::We comment on a recent article (Gomà et al 2014 Phys. Med. Biol. 59 4961-71) which compares different routes of reference dosimetry for the energy dependent beam monitor calibration in scanned proton beams. In this article, a 3% discrepancy is reported between a Faraday cup and a plane-parallel ionization chamber in t...

    journal_title:Physics in medicine and biology

    pub_type: 评论,杂志文章

    doi:10.1088/0031-9155/61/17/6585

    authors: Palmans H,Vatnitsky SM

    更新日期:2016-09-07 00:00:00

  • Paediatric entrance doses from exposure index in computed radiography.

    abstract::Over the last two years we have evaluated paediatric patient doses in projection radiography derived from exposure level (EL) in computed radiography (CR) in a large university hospital. Entrance surface air kerma (ESAK) for 3501 paediatric examinations was calculated from the EL, which is a dose index parameter relat...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/53/12/020

    authors: Vano E,Martinez D,Fernandez JM,Ordiales JM,Prieto C,Floriano A,Ten JI

    更新日期:2008-06-21 00:00:00

  • The calibration of CT Hounsfield units for radiotherapy treatment planning.

    abstract::Computer tomographic (CT) scans are used to correct for tissue inhomogeneities in radiotherapy treatment planning. In order to guarantee a precise treatment, it is important to obtain the relationship between CT Hounsfield units and electron densities (or proton stopping powers for proton radiotherapy), which is the b...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/41/1/009

    authors: Schneider U,Pedroni E,Lomax A

    更新日期:1996-01-01 00:00:00

  • Infrared and visible thermoluminescence signals of Tm-doped CaF2 measured by a semiconductor photodiode.

    abstract::A silicon semiconductor photodiode was used to measure the TL-signal of TLD-300 (CaF2:Tm) detectors irradiated with 60Co gamma rays and 226Ra alpha particles. The applied dose values varied from 0.12 to 14.3 Gy for gamma rays and from about 50 to 300 Gy for alpha particles. Because of the infrared sensitivity of the p...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/33/12/006

    authors: Meissner P,Jacob M,Rassow J

    更新日期:1988-12-01 00:00:00

  • The use of gel dosimetry for verification of electron and photon treatment plans in carcinoma of the scalp.

    abstract::In recent years there has been a large amount of research into the potential use of radiation sensitive gels for three-dimensional verification of clinical radiotherapy doses. In this paper we report the use of a MAGIC gel dosimeter (Fong et al 2001 Phys. Med. Biol. 46 3105) for the verification of a specific patient'...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/49/9/003

    authors: Trapp JV,Partridge M,Hansen VN,Childs P,Bedford J,Warrington AP,Leach MO,Webb S

    更新日期:2004-05-07 00:00:00

  • On differences in radiosensitivity estimation: TCP experiments versus survival curves. A theoretical study.

    abstract::We have compared two methods of estimating the cellular radiosensitivity of a heterogeneous tumour, namely, via cell-survival and via tumour control probability (TCP) pseudo-experiments. It is assumed that there exists intra-tumour variability in radiosensitivity and that the tumour consists predominantly of radiosens...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/60/15/N293

    authors: Stavrev P,Stavreva N,Ruggieri R,Nahum A

    更新日期:2015-08-07 00:00:00

  • Dynamic manipulation of the subharmonic scattering of phospholipid-coated microbubbles.

    abstract::In this paper, the influence of a dynamic variation in the ambient pressure on the subharmonic response of phospholipid-coated microbubbles was investigated. The ambient pressure in water was modulated by a 2.5 kHz acoustic wave with a peak amplitude of 15 kPa. We investigated the fundamental and subharmonic emissions...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/56/19/018

    authors: Faez T,Renaud G,Defontaine M,Calle S,de Jong N

    更新日期:2011-10-07 00:00:00

  • Alanine dosimetry in strong magnetic fields: use as a transfer standard in MRI-guided radiotherapy.

    abstract::Reference dosimetry in the presence of a strong magnetic field is challenging. Ionisation chambers have shown to be strongly affected by magnetic fields. There is a need for robust and stable detectors in MRI-guided radiotherapy (MRIgRT). This study investigates the behaviour of the alanine dosimeter in magnetic field...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/ab8148

    authors: Billas I,Bouchard H,Oelfke U,Shipley D,Gouldstone C,Duane S

    更新日期:2020-06-03 00:00:00

  • Comparison between TG-51 and TRS-398: electron contamination effect on photon beam-quality specification.

    abstract::Two dosimetry protocols based on absorbed dose to water have recently been implemented: TG-51 and TRS-398. These protocols use different beam-quality indices: %dd(10)x and TPR20,10. The effect of electron contamination in measurements of %dd(10)x has been proposed as a disadvantage of the TG-51. For actual measurement...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/49/1/002

    authors: Lopez Medina A,Teijeiro A,Salvador F,Medal D,Vazquez J,Salgado M,Carrion MC

    更新日期:2004-01-07 00:00:00

  • Pulsed EPR imaging: image reconstruction using selective acquisition sequences.

    abstract::Pulsed nuclear magnetic resonance imaging (NMRI) apparatus has developed very quickly. On the other hand, the development of apparatus for pulsed electron paramagnetic resonance imaging (EPRI) has been very slow. This fact is due to the extremely reduced relaxation times of the paramagnetic probes. EPR linewidths are ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/44/6/409

    authors: Di Giuseppe S,Placidi G,Brivati JA,Alecci M,Sotgiu A

    更新日期:1999-06-01 00:00:00

  • Assessment of organ-specific neutron equivalent doses in proton therapy using computational whole-body age-dependent voxel phantoms.

    abstract::Proton beams used for radiotherapy will produce neutrons when interacting with matter. The purpose of this study was to quantify the equivalent dose to tissue due to secondary neutrons in pediatric and adult patients treated by proton therapy for brain lesions. Assessment of the equivalent dose to organs away from the...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/53/3/012

    authors: Zacharatou Jarlskog C,Lee C,Bolch WE,Xu XG,Paganetti H

    更新日期:2008-02-07 00:00:00

  • Specific absorbed fractions for a revised series of the UF/NCI pediatric reference phantoms: internal photon sources.

    abstract::Assessment of radiation absorbed dose to internal organs of the body from the intake of radionuclides or, in the medical setting through the injection of radiopharmaceuticals, is generally performed based upon reference biokinetic models or patient imaging data, respectively. Biokinetic models estimate the time course...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/abc708

    authors: Schwarz BC,Godwin WJ,Wayson MB,Dewji SA,Jokisch DW,Lee C,Bolch WE

    更新日期:2020-11-03 00:00:00

  • Image-based view-angle independent cardiorespiratory motion gating and coronary sinus catheter tracking for x-ray-guided cardiac electrophysiology procedures.

    abstract::Determination of the cardiorespiratory phase of the heart has numerous applications during cardiac imaging. In this article we propose a novel view-angle independent near-real time cardiorespiratory motion gating and coronary sinus (CS) catheter tracking technique for x-ray fluoroscopy images that are used to guide ca...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/60/20/8087

    authors: Panayiotou M,Rhode KS,King AP,Ma Y,Cooklin M,O'Neill M,Gill J,Rinaldi CA,Housden RJ

    更新日期:2015-10-21 00:00:00

  • 3D thoracoscopic ultrasound volume measurement validation in an ex vivo and in vivo porcine model of lung tumours.

    abstract::The purpose of this study was to validate the accuracy and reliability of volume measurements obtained using three-dimensional (3D) thoracoscopic ultrasound (US) imaging. Artificial "tumours" were created by injecting a liquid agar mixture into spherical moulds of known volume. Once solidified, the "tumours" were impl...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/52/1/007

    authors: Hornblower VD,Yu E,Fenster A,Battista JJ,Malthaner RA

    更新日期:2007-01-07 00:00:00

  • 2D convolution kernels of ionization chambers used for photon-beam dosimetry in magnetic fields: the advantage of small over large chamber dimensions.

    abstract::This study aims at developing an optimization strategy for photon-beam dosimetry in magnetic fields using ionization chambers. Similar to the familiar case in the absence of a magnetic field, detectors should be selected under the criterion that their measured 2D signal profiles M(x,y) approximate the absorbed dose to...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/aab50c

    authors: Looe HK,Delfs B,Poppinga D,Harder D,Poppe B

    更新日期:2018-03-29 00:00:00

  • Dielectric property measurement of ocular tissues up to 110 GHz using 1 mm coaxial sensor.

    abstract::Measurement of the dielectric properties of ocular tissues up to 110 GHz was performed by the coaxial probe method. A coaxial sensor was fabricated to allow the measurement of small amounts of biological tissues. Four-standard calibration was applied in the dielectric property measurement to obtain more accurate data ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/60/16/6273

    authors: Sasaki K,Isimura Y,Fujii K,Wake K,Watanabe S,Kojima M,Suga R,Hashimoto O

    更新日期:2015-08-21 00:00:00

  • A multi-frequency sparse hemispherical ultrasound phased array for microbubble-mediated transcranial therapy and simultaneous cavitation mapping.

    abstract::Focused ultrasound (FUS) phased arrays show promise for non-invasive brain therapy. However, the majority of them are limited to a single transmit/receive frequency and therefore lack the versatility to expose and monitor the treatment volume. Multi-frequency arrays could offer variable transmit focal sizes under a fi...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/61/24/8476

    authors: Deng L,O'Reilly MA,Jones RM,An R,Hynynen K

    更新日期:2016-12-21 00:00:00

  • Analytical linear energy transfer model including secondary particles: calculations along the central axis of the proton pencil beam.

    abstract::In proton therapy, the relative biological effectiveness (RBE) depends on various types of parameters such as linear energy transfer (LET). An analytical model for LET calculation exists (Wilkens' model), but secondary particles are not included in this model. In the present study, we propose a correction factor, L se...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/61/2/740

    authors: Marsolat F,De Marzi L,Pouzoulet F,Mazal A

    更新日期:2016-01-21 00:00:00

  • An optimized leaf-setting algorithm for beam intensity modulation using dynamic multileaf collimators.

    abstract::A leaf-setting algorithm is developed for generating arbitrary beam intensity profiles in discrete levels using dynamic multileaf collimators (DMLCs). The algorithm starts with the algebraic expression for the area under the beam profile. It is shown that the coefficients in this expression can be transformed into the...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/43/6/019

    authors: Ma L,Boyer AL,Xing L,Ma CM

    更新日期:1998-06-01 00:00:00

  • The Monte Carlo calculation of integral radiation dose in xeromammography.

    abstract::A Monte Carlo computer program has been developed for the computation of integral radiation dose to the breast in xeromammography. The results are given in terms of the integral dose per unit area of the breast per unit incident exposure. The calculations have been made for monoenergetic incident photons and the resul...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/25/1/003

    authors: Dance DR

    更新日期:1980-01-01 00:00:00

  • Planning 4D intensity-modulated arc therapy for tumor tracking with a multileaf collimator.

    abstract::This study introduces a practical four-dimensional (4D) planning scheme of IMAT using 4D computed tomography (4D CT) for planning tumor tracking with dynamic multileaf beam collimation. We assume that patients can breathe regularly, i.e. the same way as during 4D CT with an unchanged period and amplitude, and that the...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/aa56b7

    authors: Niu Y,Betzel GT,Yang X,Gui M,Parke WC,Yi B,Yu CX

    更新日期:2017-02-21 00:00:00

  • Penetration of electromagnetic fields of an open-ended coaxial probe between 1 MHz and 1 GHz in dielectric skin measurements.

    abstract::An open-ended coaxial probe is often used for investigating the dielectric properties of biological tissues. The present study indicates that in addition to the probe size, the penetration of the electromagnetic (EM) fields of an open-ended coaxial probe in contact with the skin is dependent on the applied frequency b...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/44/7/404

    authors: Alanen E,Lahtinen T,Nuutinen J

    更新日期:1999-07-01 00:00:00

  • Radiobiological aspects of supralinear photographic emulsions.

    abstract::Nuclear emulsions of the Ilford K series, exposed to X-rays from 15 to 150 kVp and systematically underdeveloped, exhibit supralinear blackness--exposure curves ranging from 1- to 4-hit in character, and whose shape is the same at all excitation voltages. Processing can be so adjusted that the curve shape is well repr...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/23/6/007

    authors: Katz R,Pennington EC

    更新日期:1978-11-01 00:00:00

  • Evaluation of a novel triple-channel radiochromic film analysis procedure using EBT2.

    abstract::A novel approach to read out radiochromic film was introduced recently by the manufacturer of GafChromic film. In this study, the performance of this triple-channel film dosimetry method was compared against the conventional single-red-channel film dosimetry procedure, with and without inclusion of a pre-irradiation (...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/57/13/4353

    authors: van Hoof SJ,Granton PV,Landry G,Podesta M,Verhaegen F

    更新日期:2012-07-07 00:00:00

  • Real-time prediction and gating of respiratory motion using an extended Kalman filter and Gaussian process regression.

    abstract::Motion-adaptive radiotherapy aims to deliver a conformal dose to the target tumour with minimal normal tissue exposure by compensating for tumour motion in real time. The prediction as well as the gating of respiratory motion have received much attention over the last two decades for reducing the targeting error of th...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/60/1/233

    authors: Bukhari W,Hong SM

    更新日期:2015-01-07 00:00:00

  • On MEG forward modelling using multipolar expansions.

    abstract::Magnetoencephalography (MEG) is a non-invasive functional imaging modality based on the measurement of the external magnetic field produced by neural current sources within the brain. The reconstruction of the underlying sources is a severely ill-posed inverse problem typically tackled using either low-dimensional par...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/47/4/301

    authors: Jerbi K,Mosher JC,Baillet S,Leahy RM

    更新日期:2002-02-21 00:00:00