On differences in radiosensitivity estimation: TCP experiments versus survival curves. A theoretical study.

abstract：:Mitral and aortic valve replacement is a procedure which is common in cardiac surgery. Some of these replacement valves are mechanical and contain moving metal parts. Should the patient in whom such a valve has been implanted be involved in magnetic resonance imaging, there is a possible dangerous interaction between ...

journal_title：Physics in medicine and biology

authors： Robertson NM,Diaz-Gomez M,Condon B

更新日期：2000-12-01 00:00:00

abstract：:Instead of performing a numerical deconvolution, we propose to use a linear piecewise-continuous model of the renal impulse response function for parametric fitting of renal scintigraphy data, to obtain clinically useful renal parameters. The strengths of the present model are its simplicity and speed of computation, ...

journal_title：Physics in medicine and biology

authors： Zhang JL,Zhang L,Koh TS,Shuter B

更新日期：2003-06-21 00:00:00

abstract：:Conversion factors, which relate the kerma-area product to effective dose, have been estimated for paediatric cardiac x-ray angiography. Monte Carlo techniques have been used to calculate the conversion factors for a wide range of projection angles for children of five ages and for adults. Correction factors are provi...

journal_title：Physics in medicine and biology

authors： Schmidt PW,Dance DR,Skinner CL,Smith IA,McNeill JG

更新日期：2000-10-01 00:00:00

abstract：:The measurand relevant for the dosimetry for radiation therapy is the absorbed dose to water, DW. The Physikalisch-Technische Bundesanstalt (PTB) is establishing a secondary standard for DW for high-energy photon and electron radiation based on electron spin resonance (ESR) of the amino acid alanine. For practical app...

journal_title：Physics in medicine and biology

authors： Anton M

更新日期：2008-03-07 00:00:00

abstract：:Generally, the inverse planning of radiation therapy consists mainly of the fluence optimization. The beam angle optimization (BAO) in intensity-modulated radiation therapy (IMRT) consists of selecting appropriate radiation incidence directions and may influence the quality of the IMRT plans, both to enhance better or...

journal_title：Physics in medicine and biology

authors： Rocha H,Dias JM,Ferreira BC,Lopes MC

更新日期：2013-05-07 00:00:00

abstract：:Analytic solutions to the time-dependent multiregion bioheat equation are evaluated numerically for cartesian and spherical models. Principle and alternate branch contributions to the solutions are examined. The calculations include a parametric investigation and analyses of temperature behaviour in idealised upper th...

journal_title：Physics in medicine and biology

authors： Durkee JW Jr,Antich PP,Lee CE

更新日期：1990-07-01 00:00:00

abstract：:Prenatal events such as intrauterine growth restriction and increased cardiovascular risk in later life have been shown to be associated with an increased intima-media thickness (aIMT) of the abdominal aorta in the fetus. In order to assess and manage atherosclerosis and cardiovascular disease risk in adults and child...

journal_title：Physics in medicine and biology

authors： Veronese E,Tarroni G,Visentin S,Cosmi E,Linguraru MG,Grisan E

更新日期：2014-11-07 00:00:00

abstract：:The aim of the study is to determine PTV margin for inter-observer variability in the volumetric modulated arc therapy (VMAT) prostate radiotherapy with high-dose volumetric CT (HDVCT) and conventional helical CT (CCT) for planning. Secondly to investigate the impact of geometric (PTV expansion) and dosimetric (confor...

journal_title：Physics in medicine and biology

authors： Cho YB,Alasti H,Kong V,Catton C,Berlin A,Chung P,Bayley A,Jaffray D

更新日期：2019-03-14 00:00:00

abstract：:All radiation therapy treatment planning relies on accurate dose calculation. Uncertainties in dosimetric prediction can significantly degrade an otherwise optimal plan. In this work, we introduce a robust optimization method which handles dosimetric errors and warrants for high-quality IMRT plans. Unlike other dose e...

journal_title：Physics in medicine and biology

authors： Nohadani O,Seco J,Martin BC,Bortfeld T

更新日期：2009-06-07 00:00:00

abstract：:Voxel phantoms are human models based on computed tomographic or magnetic resonance images obtained from high-resolution scans of a single individual. They consist of a huge number of volume elements (voxels) and are at the moment the most precise representation of the human anatomy. The purpose of this paper is to in...

journal_title：Physics in medicine and biology

authors： Petoussi-Henss N,Zanki M,Fill U,Regulla D

更新日期：2002-01-07 00:00:00

abstract：:Most existing spatiotemporal multi-dipole approaches for MEG/EEG source localization assume that the dipoles are active for the full time range being analysed. If the actual time range of activity of sources is significantly shorter than the time range being analysed, the detectability, localization and time-course de...

journal_title：Physics in medicine and biology

authors： Jun SC,George JS,Plis SM,Ranken DM,Schmidt DM,Wood CC

更新日期：2006-05-21 00:00:00

abstract：:At the UMC Utrecht a prototype MR-linac has been installed. The system consists of an 8 MV Elekta linear accelerator and a 1.5 T Philips MRI system. This paper investigates the performance of the IC PROFILER™, a multi-axis ionization chamber array, in a 1.5 T magnetic field. The influence of the magnetic field on the ...

journal_title：Physics in medicine and biology

authors： Smit K,Kok JG,Lagendijk JJ,Raaymakers BW

更新日期：2014-04-07 00:00:00

abstract：:Proton therapy potentially offers excellent dose conformality and reduction in integral dose. The superior dose distribution is, however, much more sensitive to the radiological depth along the beam path than for photon fields. Variations in this depth due to inaccurate planning calculation, setup uncertainty, respira...

journal_title：Physics in medicine and biology

authors： Lu HM

更新日期：2008-03-07 00:00:00

abstract：:Identification of prostate gold fiducial markers in magnetic resonance imaging (MRI) images is challenging when CT images are not available, due to misclassifications from intra-prostatic calcifications. It is also a time consuming task and automated identification methods have been suggested as an improvement for bot...

journal_title：Physics in medicine and biology

authors： Gustafsson CJ,Swärd J,Adalbjörnsson SI,Jakobsson A,Olsson LE

更新日期：2020-11-12 00:00:00

abstract：:Intensity modulated radiation therapy (IMRT) inverse planning using total-variation (TV) regularization has been proposed to reduce the complexity of fluence maps and facilitate dose delivery. Conventionally, the optimization problem with L-1 norm is solved with quadratic programming (QP), which is time consuming and ...

journal_title：Physics in medicine and biology

authors： Kim H,Suh TS,Lee R,Xing L,Li R

更新日期：2012-07-07 00:00:00

abstract：:Although physical metrics can objectively characterize computed tomography (CT) image quality, quantitative approaches to predict human observer performance are more accurate and clinically relevant. This study compared a modified channelized Hotelling model observer (CHO) with human observers in a shape discriminatio...

journal_title：Physics in medicine and biology

authors： Zhang Y,Leng S,Yu L,Carter RE,McCollough CH

更新日期：2014-07-07 00:00:00

abstract：:Cavity theories are used to relate the dose in a medium to the dose in a cavity. No satisfactory analytical approach exists for the case of intermediate cavities, such as TLDs, when interface effects are important. Burlin proposed a general cavity theory that accounts for the cavity size but which ignores interface ef...

journal_title：Physics in medicine and biology

authors： Frujinoiu C

更新日期：2001-04-01 00:00:00

abstract：:Experimental radiobiological investigations of fast neutron beams involve irradiation of thin cell layers. The irradiation of cells is done either in free air or with a material such as graphite, TE plastic or bone-equivalent plastic covering the cells. This paper discusses the computed dose distributions in LET at sh...

journal_title：Physics in medicine and biology

authors： Bhatia DP,Nagarajan PS

更新日期：1979-09-01 00:00:00

abstract：:This study aims to build a feasible mathematical model to analyze the mass evolution of NSCLC during standard fractionated radiotherapy. Seventy-three cases of NSCLC who were received radiotherapy with prescription dose of 2 Gy  ×  30 fx were selected retrospectively and divided into adenocarcinoma (ADC) group and squ...

journal_title：Physics in medicine and biology

authors： Chen J,Wang K,Jian J,Zhang W

更新日期：2019-11-26 00:00:00

abstract：:The aim of this study is to determine the impact of longitudinal micro-CT imaging on the growth of B16F1 tumours in C57BL/6 mice. Sixty mice received 2 × 10(5) B16F1 cells subcutaneously in the hind flank and were divided into control (no scan), 'low-dose' (80 kVp, 70 mA, 8 s, 0.07 Gy), 'medium-dose' (80 kVp, 50 mA, 3...

journal_title：Physics in medicine and biology

authors： Foster WK,Ford NL

更新日期：2011-01-21 00:00:00

abstract：:Using MRI for radiotherapy treatment planning and image guidance is appealing as it provides superior soft tissue information over CT scans and avoids possible systematic errors introduced by aligning MR to CT images. This study presents a method that generates Synthetic CT (MRCT) volumes by performing probabilistic t...

journal_title：Physics in medicine and biology

authors： Liu L,Jolly S,Cao Y,Vineberg K,Fessler JA,Balter JM

更新日期：2017-04-21 00:00:00

abstract：:We find the dose distribution that maximizes the tumour control probability (TCP) for a fixed mean tumour dose per fraction. We consider a heterogeneous tumour volume having a radiation response characterized by the linear quadratic model with heterogeneous radiosensitivity and repopulation rate that may vary in time....

journal_title：Physics in medicine and biology

authors： Levin-Plotnik D,Hamilton RJ

更新日期：2004-02-07 00:00:00

abstract：:A radiofrequency and field-gradient pulse sequence is presented permitting the non-invasive, volume-selective and spectroscopically resolved determination of incoherent transport parameters with the aid of an NMR field-gradient method. With proton NMR, diffusion or (quasi-incoherent) perfusion coefficients as low as 1...

journal_title：Physics in medicine and biology

authors： Klammler F,Kimmich R

更新日期：1990-01-01 00:00:00

abstract：:Several types of intravascular ultrasound (IVUS) catheters are connected to a motor at their proximal end, in order to let the catheter rotate around its length axis. However, the rotation of the distal axis tip does not follow exactly the rotation of the motor, since the catheter axis is not completely torsion-free a...

journal_title：Physics in medicine and biology

authors： Konings MK,van Leeuwen TG,Mali WP,Viergever MA

更新日期：1998-05-01 00:00:00

abstract：:Blood was withdrawn from the ante-cubital vein of five normal volunteers and the erythrocytes were washed and resuspended in isotonic saline. The rate of descent of the erythrocyte-saline boundary was measured every hour for a period of at least 4 h for different suspended cell concentrations. The velocity of this bou...

journal_title：Physics in medicine and biology

authors： Smallwood RH,Tindale WB,Trowbridge EA

更新日期：1985-02-01 00:00:00

abstract：:Compton scatter poses a significant threat to volumetric x-ray computed tomography, bringing cupping and streak artefacts thus impacting qualitative and quantitative imaging procedures. To perform appropriate scatter compensation, it is necessary to estimate the magnitude and spatial distribution of x-ray scatter. The...

journal_title：Physics in medicine and biology

authors： Akbarzadeh A,Ay MR,Ghadiri H,Sarkar S,Zaidi H

更新日期：2010-04-21 00:00:00

abstract：:At low and intermediate frequencies, the strength of the induced electric field is used as dosimetric quantity for human protection in the International Commission on Non-Ionizing Radiation Protection (ICNIRP) guidelines. To compute the induced electric field, numerical methods based on anatomically realistic voxel mo...

journal_title：Physics in medicine and biology

authors： Soldati M,Laakso I

更新日期：2020-01-10 00:00:00

abstract：:As the use of radiofrequency (RF) electromagnetic (EM) fields has increased along with increased use of wireless communication, the possible related health risks have also been widely discussed. One safety aspect is the interaction of medical implants and RF devices like mobile phones. In the literature, effects on ac...

journal_title：Physics in medicine and biology

authors： Virtanen H,Keshvari J,Lappalainen R

更新日期：2007-03-07 00:00:00

abstract：:A hydrogen clearance technique for the measurement of capillary blood flow in skeletal muscle (both resting and working) and the beating heart in experimental animals is described. Various methods for introducing the hydrogen into the region of measurement are compared, together with the appropriate methods for evalua...

journal_title：Physics in medicine and biology

authors： Harrison DK,Kessler M

更新日期：1989-10-01 00:00:00

abstract：:Fractional flow reserve (FFR) provides an objective physiological evaluation of stenosis severity. A technique that can measure FFR using only angiographic images would be a valuable tool in the cardiac catheterization laboratory. To perform this, the diseased blood flow can be measured with a first pass distribution ...

journal_title：Physics in medicine and biology

authors： Wong JT,Molloi S

更新日期：2008-07-21 00:00:00