The Agrobacterium Type VI Secretion System: A Contractile Nanomachine for Interbacterial Competition.

Abstract:

:The bacterial type VI secretion system (T6SS) is a contractile nanomachine dedicated to delivering molecules out of bacterial cells. T6SS-encoding loci are in the genome sequences of many Gram-negative bacteria, and T6SS has been implicated in a plethora of roles. In the majority of cases, the T6SSs deliver effector proteins in a contact-dependent manner to antagonize other bacteria. Current models suggest that the effectors are deployed to influence social interactions in microbial communities. In this chapter, we describe the structure, function, and regulation of the T6SS and its effectors. We provide focus on the T6SS of Agrobacterium tumefaciens, the causative agent of crown gall disease, and relate the role of the T6SS to the ecology of A. tumefaciens.

authors

Wu CF,Smith DA,Lai EM,Chang JH

doi

10.1007/82_2018_99

subject

Has Abstract

pub_date

2018-01-01 00:00:00

pages

215-231

eissn

0070-217X

issn

2196-9965

journal_volume

418

pub_type

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