Activity of fosfomycin when tested against US contemporary bacterial isolates.

Abstract:

:Fosfomycin and comparators were susceptibility tested against over 2200 contemporary clinical isolates from US medical centers. Fosfomycin was active against Enterobacterales (MIC50/90, 4/16 μg/mL), including multidrug-resistant isolates. Potent activity was exhibited against gram-positive organisms, including Staphylococcus aureus (MIC50/90, 4/8 μg/mL). Fosfomycin may provide a promising alternative option for treatment of infections where resistant bacteria may occur.

authors

Flamm RK,Rhomberg PR,Watters AA,Sweeney K,Ellis-Grosse EJ,Shortridge D

doi

10.1016/j.diagmicrobio.2018.08.010

subject

Has Abstract

pub_date

2019-02-01 00:00:00

pages

143-146

issue

2

eissn

0732-8893

issn

1879-0070

pii

S0732-8893(18)30304-3

journal_volume

93

pub_type

杂志文章
  • The current and future impact of antimicrobial resistance among nosocomial bacterial pathogens.

    abstract::The selection of drug-resistant microorganisms has generally been associated with the widespread use of antimicrobial agents. The emergence of these antimicrobial resistance has an undesirable impact that often severely limits the use of these drugs that could have otherwise been identified as "drugs of first choice."...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章,评审

    doi:

    authors: Jones RN

    更新日期:1992-02-01 00:00:00

  • Leukocytoclastic vasculitis complicating Klebsiella pneumoniae bacteremia.

    abstract::A 79-year old woman, with a history of hypertension, presented with clinical features of congestive heart failure, fever, a purpuric rash, and left lower quadrant abdominal tenderness. Contrast computed tomography scan of the abdomen showed features of acute diverticulitis, and blood culture was subsequently positive ...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章

    doi:10.1016/s0732-8893(00)00151-6

    authors: Lum PN,Woo PC,Wong SS,Yuen K

    更新日期:2000-08-01 00:00:00

  • A five-year multicenter study of the susceptibility of the Bacteroides fragilis group isolates to cephalosporins, cephamins, penicillins, clindamycin, and metronidazole in the United States.

    abstract::Over 2800 clinical strains of the Bacteroides fragilis group were collected during a 5-year period from ten geographically separate sites and tested for their susceptibility to various antimicrobial agents using a broth microdilution method. Among the cephalosporins, ceftizoxime was the most active (13% resistance) an...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章,多中心研究

    doi:10.1016/0732-8893(94)90026-4

    authors: Aldridge KE,Gelfand M,Reller LB,Ayers LW,Pierson CL,Schoenknecht F,Tilton RC,Wilkins J,Henderberg A,Schiro DD

    更新日期:1994-04-01 00:00:00

  • In vitro activity of antituberculous agents against Mycobacterium tuberculosis isolates from Bogota, DC (Colombia) evaluated by the ETest.

    abstract::Tuberculosis tests for antimicrobial susceptibility takes weeks. However, delayed therapy, can compromise the patient, as well as lead to an increase in disease incidence. Among infectious diseases, tuberculosis continues to be a leading cause of death in the world. The E-test is a new concept for Minimal Inhibitory C...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章

    doi:10.1016/s0732-8893(99)00068-1

    authors: Sánchez L,Londoño D,Arango AI,Mattar S

    更新日期:1999-10-01 00:00:00

  • QuantiFERON-TB Gold In-Tube as help for the diagnosis of tuberculosis in a French pediatric hospital.

    abstract::The diagnosis of tuberculosis (TB) is difficult in children. The pediatricians are waiting for new and rapid tests that are easy to realize and that are performed better than tuberculin skin test (TST). We presented here the evaluation of QuantiFERON-TB Gold In-Tube (QFT-G IT) in the Children Hospital of Nancy. Fifty-...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章

    doi:10.1016/j.diagmicrobio.2009.11.002

    authors: Grare M,Derelle J,Dailloux M,Laurain C

    更新日期:2010-04-01 00:00:00

  • Susceptibility of clinical isolates of Candida spp. to terconazole and other azole antifungal agents.

    abstract::Terconazole is a triazole ketal derivative with potent, broad-spectrum antifungal activity. We investigated the in vitro activity of terconazole, miconazole, and clotrimazole, against 94 clinical isolates of Candida spp.: C. albicans (n = 68), C. tropicalis (n = 18), and C. parapsilosis (n = 8). In vitro susceptibilit...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章

    doi:10.1016/0732-8893(89)90079-5

    authors: Pfaller MA,Gerarden T

    更新日期:1989-11-01 00:00:00

  • Frequency of occurrence and antimicrobial susceptibility of bacteria isolated from patients hospitalized with bloodstream infections in United States medical centers (2015-2017).

    abstract::The frequency and antimicrobial susceptibility of organisms causing bloodstream infections in the United States were evaluated by consecutively collecting (1/patient) 9210 bacterial isolates from 33 US medical centers in 2015-2017. Isolates were susceptibility tested by reference broth microdilution methods. Whole gen...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.diagmicrobio.2019.06.002

    authors: Sader HS,Castanheira M,Streit JM,Flamm RK

    更新日期:2019-11-01 00:00:00

  • Identification of cryptic Candida species by MALDI-TOF mass spectrometry, not all MALDI-TOF systems are the same: focus on the C. parapsilosis species complex.

    abstract::Data about the performance of MALDI-TOF mass spectrometry against cryptic Candida species are limited. According to our findings within the C. parapsilosis species complex, microbiologists should be aware that the choice of the instrument is critical for accurate species identification due to the risk of misidentifica...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章

    doi:10.1016/j.diagmicrobio.2016.08.028

    authors: Haas M,Grenouillet F,Loubersac S,Ariza B,Pepin-Puget L,Alvarez-Moreno CA,Valderrama-Beltrán SL,Lavergne RA,Le Pape P,Morio F

    更新日期:2016-12-01 00:00:00

  • The importance of volume of blood cultured in the detection of bacteremia and fungemia.

    abstract::An analysis was made on the basis of 5,389 isolates from 5,008 positive blood cultures of the relative yields from 10, 20, and 30 ml of blood. Average yields from cultures of 20 and 30 ml of blood were, respectively, 38 and 61% greater than that from 10 ml of blood. ...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章

    doi:10.1016/0732-8893(83)90039-1

    authors: Ilstrup DM,Washington JA 2nd

    更新日期:1983-06-01 00:00:00

  • Identification of CTX-M beta-lactamases in Escherichia coli from hospitalized patients and residents of long-term care facilities.

    abstract::Bacteria harboring CTX-M extended-spectrum beta-lactamases (ESBLs) have been identified worldwide, with most reports coming from regions outside North America. We have identified CTX-M enzymes in 31% of ESBL-positive Escherichia coli isolates from our hospital and more than half (53%) of the isolates from associated l...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章

    doi:10.1016/j.diagmicrobio.2009.11.012

    authors: Urban C,Mariano N,Bradford PA,Tuckman M,Segal-Maurer S,Wehbeh W,Grenner L,Colon-Urban R,Johnston B,Johnson JR,Rahal JJ

    更新日期:2010-04-01 00:00:00

  • Treatment of ordinary and penicillinase-producing strains of Neisseria gonorrhoeae in Mexico City.

    abstract::Since being recognized in 1976 and 1983, respectively, penicillinase-producing strains of Neisseria gonorrhoeae (PPNG) and chromosomally mediated resistance (CMRNG) have attained a worldwide distribution. The high endemicity of both types of resistance in some regions precludes the continued routine use of procaine pe...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/0732-8893(87)90041-1

    authors: Calderón E,Conde CJ,de la Cruz R,Narcio L,Hirata C

    更新日期:1987-09-01 00:00:00

  • Evaluation of rapid culture centrifugation method for adenovirus detection in stools.

    abstract::Routine laboratory testing for adenovirus (Adv) requires a procedure that is rapid and reliable, especially for samples from children and immunosuppressed patients, when diarrhea may signal the onset of severe gastrointestinal disorders. An improved culture technique for Adv isolation, using centrifugation step of 24-...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章

    doi:10.1016/0732-8893(95)00271-5

    authors: Durepaire N,Ranger-Rogez S,Denis F

    更新日期:1996-01-01 00:00:00

  • Evaluation of commercial serologic test reagents for immunoidentification of medically important aspergilli.

    abstract::We evaluated commercial serodiagnostic test reagents from Greer Laboratories (GL), Lenoir, NC; Immuno-mycologics, Inc. (IMI), Norman, OK; and Scott Laboratories (SL), Fiskville, RI; for their ability to detect Aspergillus spp. exoantigens and group them in their proper series. We detected 87 culture extracts from code...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章

    doi:10.1016/0732-8893(87)90170-2

    authors: Sekhon AS,Standard PG,Kaufman L,Garg AK

    更新日期:1987-11-01 00:00:00

  • Varicella associated intracerebral hemorrhage in the absence of thrombocytopenia.

    abstract::A young woman with varicella complicated by streptococcal cellulitis developed an intracerebral bleed in the absence of thrombocytopenia, serious coagulopathy, or a detectable vascular lesion. We postulate that during the acute infection with varicella, a cerebral endothelial lesion was produced which later caused the...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章

    doi:10.1016/0732-8893(89)90103-x

    authors: Fikrig E,Barg NL

    更新日期:1989-07-01 00:00:00

  • Loop-mediated isothermal amplification (LAMP) for the rapid detection of Mycoplasma genitalium.

    abstract::Mycoplasma genitalium is a sexually transmissible, pathogenic bacterium and a significant cause of nongonococcal urethritis in both men and women. Due to the difficulty of the culture of M. genitalium from clinical samples, the laboratory diagnosis of M. genitalium infection is almost exclusively carried out using nuc...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章

    doi:10.1016/j.diagmicrobio.2015.05.010

    authors: Edwards T,Burke P,Smalley HB,Gillies L,Longhurst D,Vipond B,Hobbs G

    更新日期:2015-09-01 00:00:00

  • Selection of Enterococcus faecium strains with stable and unstable resistance to the streptogramin RP 59500 using stepwise in vitro exposure.

    abstract::Therapy of vancomycin-resistant enterococcal infections is an increasing problem for many large medical centers. One promising agent for use against Enterococcus faecium is RP 59500 (Quinupristin/Dalfopristin). To assess the potential for emergence of resistant strains during clinical trials with this new compound, we...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章

    doi:10.1016/0732-8893(96)00067-3

    authors: Millichap J,Ristow TA,Noskin GA,Peterson LR

    更新日期:1996-05-01 00:00:00

  • Evaluation of the Abbott ARCHITECT Toxo IgM assay.

    abstract::Development of the ARCHITECT Toxo IgM assay has been done to assist the clinician in acute Toxoplasma gondii infection detection, especially in pregnant women. Its use, in conjunction with ARCHITECT Toxo IgG and Toxo Avidity assays, will provide an array of assays particularly useful in the monitoring of pregnant fema...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章

    doi:10.1016/j.diagmicrobio.2009.03.016

    authors: Sickinger E,Braun HB,Praast G,Stieler M,Gundlach C,Birkenbach C,Prostko J,Palafox MA,Frias E,Hsu S,Matias M,Pucci D,Hausmann M,Sagel U,Smith D

    更新日期:2009-07-01 00:00:00

  • Serological and molecular detection of Mycoplasma pneumoniae in children with community-acquired lower respiratory tract infections.

    abstract::This study was designed to evaluate the incidence of Mycoplasma pneumoniae infection in children with community-acquired lower respiratory tract infections (LRTIs). A total of 245 patients 6 months to 12 years of age were investigated for M. pneumoniae employing serological tests, polymerase chain reaction (PCR), nest...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章

    doi:10.1016/j.diagmicrobio.2019.03.010

    authors: Kumar S,Garg IB,Sethi GR

    更新日期:2019-09-01 00:00:00

  • Vibrio parahaemolyticus (Kanagawa-negative) wound infection in a hospital dietary employee.

    abstract::Vibrio parahaemolyticus is an estuarine bacterium that is a major cause of gastroenteritis worldwide. Occasionally, this organism has also been shown to be the causative agent of wound infections. In almost all cases of gastrointestinal disease only strains that produce hemolysin ("Kanagawa-positive") are implicated. ...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章

    doi:10.1016/0732-8893(88)90059-4

    authors: Sautter RL,Taylor JS,Oliver JD,O'Donnell C

    更新日期:1988-01-01 00:00:00

  • Evaluation of the in vitro activity of cefepime compared to other broad-spectrum cephalosporins against clinical isolates from eighteen Brazilian hospitals by using the Etest.

    abstract::The in vitro activity of cefepime was compared to that of ceftazidime, ceftriaxone, and cefotaxime in a multicenter study involving 10 clinical microbiology laboratories and clinical isolates from 18 Brazilian hospitals from 7 cities (4 states). A total of 982 isolates consecutively collected between December 1995 and...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章

    doi:10.1016/s0732-8893(97)00015-1

    authors: Sader HS,Mimiça I,Rossi F,Zoccoli C,Montelli AC,Sampaio JL,Segura AJ,Magalhães M,Nowakonski A,Mendes CM

    更新日期:1997-06-01 00:00:00

  • Changes in the balance between Treg and Th17 cells in patients with chronic hepatitis B.

    abstract::The purpose of this study was to explore the role of Treg cells, Th17 cells and cytokines associated with Treg/Th17 differentiation in the occurrence, development and outcome of chronic hepatitis B (CHB). To do so, we detected populations of Treg and Th17 cells and their associated cytokines in the peripheral blood of...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章

    doi:10.1016/j.diagmicrobio.2013.04.026

    authors: Su ZJ,Yu XP,Guo RY,Ming DS,Huang LY,Su ML,Deng Y,Lin ZZ

    更新日期:2013-08-01 00:00:00

  • Methicillin-resistant Staphylococcus aureus. Optimization of the agar screen plate method.

    abstract::Swab inoculation of oxacillin agar screen plates was compared with drop inoculation for detection of methicillin-resistant Staphylococcus aureus. The poor sensitivity of the swab method (59%) was related to heteroresistance of the S. aureus isolates. We recommend the drop method (100% sensitivity) because interpretati...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章

    doi:10.1016/0732-8893(94)90077-9

    authors: Alfa MJ,Ongsansoy E,Hoban S,Mathew T,Greenaway C

    更新日期:1994-02-01 00:00:00

  • Assessment of ceftaroline fosamil in the treatment of community-acquired bacterial pneumonia due to Streptococcus pneumoniae: insights from two randomized trials.

    abstract::Ceftaroline fosamil resulted in higher cure rates than ceftriaxone in patients with community-acquired bacterial pneumonia in 2 randomized trials (FOCUS 1 and FOCUS 2). The present analysis examines the subgroup of patients with Streptococcus pneumoniae infection to determine whether the apparent difference in cure ra...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.diagmicrobio.2012.12.002

    authors: Shorr AF,Kollef M,Eckburg PB,Llorens L,Friedland HD

    更新日期:2013-03-01 00:00:00

  • Proteolytic activity of Candida albicans and other yeasts.

    abstract::Clinical isolates of C. albicans (75 strains) and other yeasts (20 strains) were evaluated for their ability to produce a carboxyl acid proteinase in an effort to assess its potential role as a virulence factor. Yeasts were categorized as to the infectious process present in the patient: (1) isolates from patients wit...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章

    doi:10.1016/0732-8893(85)90060-4

    authors: Schreiber B,Lyman CA,Gurevich J,Needham CA

    更新日期:1985-01-01 00:00:00

  • Bipolaris oryzae, a novel fungal opportunist causing keratitis.

    abstract::We report a case of mycotic keratitis caused by Bipolaris oryzae with predisposing trauma from a foreign body. The fungus was identified by sequencing the internal transcribed spacer region, translation elongation factor 1α (TEF1) gene, and partial glyceraldehyde-3-phosphate dehydrogenase (GPDH) gene, and the species ...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章

    doi:10.1016/j.diagmicrobio.2015.11.020

    authors: Wang L,Al-Hatmi AM,Lai X,Peng L,Yang C,Lai H,Li J,Meis JF,de Hoog GS,Zhuo C,Chen M

    更新日期:2016-05-01 00:00:00

  • Survey of diagnostic testing for respiratory syncytial virus (RSV) in adults: Infectious disease physician practices and implications for burden estimates.

    abstract::Respiratory syncytial virus (RSV) often causes respiratory illness in adults. Over 40 RSV vaccine and monoclonal antibody products are currently in preclinical development or clinical trials. Because RSV diagnostic practices may impact disease burden estimates, we investigated infectious disease physicians' RSV diagno...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章

    doi:10.1016/j.diagmicrobio.2017.12.011

    authors: Allen KE,Beekmann SE,Polgreen P,Poser S,St Pierre J,Santibañez S,Gerber SI,Kim L

    更新日期:2018-11-01 00:00:00

  • Hemophilus aphrophilus vertebral osteomyelitis: a case report and literature review.

    abstract::We report a 60-yr-old diabetic female who developed vertebral osteomyelitis and discitis due to Hemophilus aphrophilus, and review three previously reported cases of this uncommon infection. Predisposing factors, clinical features, and treatment of H. aphrophilus vertebral osteomyelitis are discussed. ...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章,评审

    doi:10.1016/0732-8893(87)90171-4

    authors: Gribble MJ,Hunter T

    更新日期:1987-11-01 00:00:00

  • Molecular types and antimicrobial susceptibility patterns of Clostridium difficile isolates in different epidemiological settings in a tertiary care center in Israel.

    abstract::The aims of this prospective study were to examine the correlation between the molecular types and the antimicrobial susceptibility patterns of Clostridium difficile isolates with the source of acquisition and the occurrence of C. difficile infections (CDI) in a tertiary center in Israel. All available isolates from c...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章

    doi:10.1016/j.diagmicrobio.2016.08.021

    authors: Miller-Roll T,Na'amnih W,Cohen D,Carmeli Y,Adler A

    更新日期:2016-12-01 00:00:00

  • Rapid differentiation between clinically relevant mycobacteria in microscopy positive clinical specimens and mycobacterial isolates by line probe assay.

    abstract::The Inno LiPA Mycobacteria assay, based on PCR amplification of the 16-23S rRNA spacer region of Mycobacterium species, has been designed for identification of mycobacteria grown in culture media and discrimination between Mycobacterium tuberculosis complex, M. avium, M. intracellulare, M. kansasii, M. gordonae, M. xe...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章

    doi:10.1016/s0732-8893(02)00406-6

    authors: Johansen IS,Lundgren BH,Thyssen JP,Thomsen VØ

    更新日期:2002-08-01 00:00:00

  • Cytomegalovirus antibody detection in blood donors and mothers of very low birth weight neonates by using three serologic methods.

    abstract::We compared three serologic methods for cytomegalovirus (CMV) antibody detection and determined the CMV antibody seroprevalence of blood donors and mothers of very low birth weight (less than 1250 g) neonates in the Greater Hartford region. CMV serology was determined for 577 healthy blood donors as well as for 147 mo...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章

    doi:10.1016/0732-8893(92)90035-r

    authors: Eisenfeld L,McLaughlin JC,Mayo D,Klevjer-Anderson P,Silver H,Krause P,Anderson J,Herson V,Savidakis J,Lazar AM

    更新日期:1992-02-01 00:00:00