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Bipolaris oryzae, a novel fungal opportunist causing keratitis.

Abstract：

:We report a case of mycotic keratitis caused by Bipolaris oryzae with predisposing trauma from a foreign body. The fungus was identified by sequencing the internal transcribed spacer region, translation elongation factor 1α (TEF1) gene, and partial glyceraldehyde-3-phosphate dehydrogenase (GPDH) gene, and the species identity was confirmed on the basis of its characteristic conidial phenotype. The patient was treated with surgical intervention and antifungal agents, including intravenous fluconazole (FLC), oral itraconazole, topical 0.15% amphotericin B eye drops, and 0.5% FLC eye drops. To our knowledge, this is the first report of mycotic keratitis caused by B. oryzae worldwide.

journal_name

Diagn Microbiol Infect Dis

journal_title

Diagnostic microbiology and infectious disease

authors

Wang L,Al-Hatmi AM,Lai X,Peng L,Yang C,Lai H,Li J,Meis JF,de Hoog GS,Zhuo C,Chen M

doi

10.1016/j.diagmicrobio.2015.11.020

subject

Has Abstract

pub_date

2016-05-01 00:00:00

pages

61-5

issue

1

eissn

0732-8893

issn

1879-0070

pii

S0732-8893(15)00435-6

journal_volume

85

pub_type

杂志文章

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