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Evaluation of commercial serologic test reagents for immunoidentification of medically important aspergilli.

Abstract：

:We evaluated commercial serodiagnostic test reagents from Greer Laboratories (GL), Lenoir, NC; Immuno-mycologics, Inc. (IMI), Norman, OK; and Scott Laboratories (SL), Fiskville, RI; for their ability to detect Aspergillus spp. exoantigens and group them in their proper series. We detected 87 culture extracts from coded cultures of Aspergillus groups and heterologous fungi against anti-A. fumigatus, A. flavus, A. nidulans, A. niger, and A. terreus sera in the presence of their corresponding antigens. Parallel control studies were performed using serological reagents from both laboratories. The IMI reagents accurately grouped all the isolates. The A. nidulans and A. terreus reactions, however, were significantly weaker than those noted with the control reagents. GL and SL do not supply A. nidulans and A. terreus reagents. Their available reagents correctly grouped the A. fumigatus, A. flavus, and A. niger isolates. Our results indicate that the commercial serodiagnostic reagents for aspergillosis can be effectively used to accurately immunoidentify the medically important Aspergillus spp.

journal_name

Diagn Microbiol Infect Dis

journal_title

Diagnostic microbiology and infectious disease

authors

Sekhon AS,Standard PG,Kaufman L,Garg AK

doi

10.1016/0732-8893(87)90170-2

subject

Has Abstract

pub_date

1987-11-01 00:00:00

pages

183-7

issue

3

eissn

0732-8893

issn

1879-0070

pii

0732-8893(87)90170-2

journal_volume

8

pub_type

杂志文章

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