Abstract:
:An antimicrobial resistance surveillance study in Japan is presented representing the second year (Phase II) results from 22 medical centers. Each participant laboratory tested (Etest, AB BIODISK, Solna, Sweden) 100 organisms, 10 strains each from 10 species groups including Escherichia coli, Klebsiella spp., Enterobacter spp., Citrobacter spp., indole-positive Proteae, Serratia spp., Acinetobacter spp., Pseudomonas aeruginosa, and oxacillin-susceptible Staphylococcus aureus and coagulase-negative staphylococci. Generally only modest variations in the activity of the studied broad-spectrum beta-lactams was observed compared to the study a year before. Specifically, extended spectrum beta-lactamase (ESBL) rates in E. coli increased (2.9 to 8.1%), but the ESBL rate in Klebsiella spp. fell (8.6 to 5.0%). Overall the resistance to the beta-lactams varied from a 4.7% decrease (ceftazidime as a consequence of a modified staphylococcal breakpoint criteria) to a 1.0% increase (cefepime, not significant). The rank order of spectrums in 1998 only changed for cefoperazone-sulbactam (6.1% resistance) that was active against more strains than cefpirome (6.8% resistance). The overall spectrum rank order for the 1998 Japan sample (% resistance) was: cefepime (3.2%) > imipenem (4.1%) > cefoperazone-sulbactam (6.1%) > cefpirome (6.8%) > ceftazidime (8.4%) > piperacillin (19.9%). As with a similar study in 1997, imipenem-resistant isolates of P. aeruginosa and Serratia spp. were discovered with metalloenzymes, usually found in the same medical centers. These results demonstrate the continued in vitro activity and potential sustained clinical efficacy of several broad-spectrum beta-lactams in Japan. Rapid emergence of new or novel resistance were not wide spread using a precise quantitative MIC system. Continued surveillance in this nation would be prudent to document the activity of this clinically valuable class of safe, antimicrobial agents.
journal_name
Diagn Microbiol Infect Disjournal_title
Diagnostic microbiology and infectious diseaseauthors
Lewis MT,Yamaguchi K,Biedenbach DJ,Jones RNdoi
10.1016/s0732-8893(99)00120-0subject
Has Abstractpub_date
1999-12-01 00:00:00pages
307-15issue
4eissn
0732-8893issn
1879-0070pii
S0732889399001200journal_volume
35pub_type
临床试验,杂志文章abstract::We previously reported that adenosine 5'-triphosphate (ATP) inhibited the growth of various bacteria, including mycobacteria, Staphylococcus, and Pseudomonas, without damaging bacterial surface structures. Notably, ATP's antibacterial activity was found to be attributable to its iron-chelating ability. ATP exhibited c...
journal_title:Diagnostic microbiology and infectious disease
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doi:10.1016/j.diagmicrobio.2017.04.012
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abstract::In order to assess the significance of Candida colonization of intravascular catheters (IVC) in patients without documented candidemia, we retrospectively reviewed all Candida-positive IVC tip cultures over a 4-year period. Cases were defined as those with a culture yielding ≥15 colony-forming units of Candida spp. th...
journal_title:Diagnostic microbiology and infectious disease
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journal_title:Diagnostic microbiology and infectious disease
pub_type: 杂志文章
doi:10.1016/0732-8893(84)90029-4
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pub_type: 杂志文章
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journal_title:Diagnostic microbiology and infectious disease
pub_type: 杂志文章,评审
doi:
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abstract::Development of a new phenotypic technique for rapid antimicrobial susceptibility testing (AST) of methicillin-resistant Staphylococcus aureus is presented. The new technique combines bacterial culturing and specific immunometric detection in a single separation-free process. The technique uses dry chemistry reagents a...
journal_title:Diagnostic microbiology and infectious disease
pub_type: 杂志文章
doi:10.1016/j.diagmicrobio.2008.07.007
更新日期:2008-11-01 00:00:00
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journal_title:Diagnostic microbiology and infectious disease
pub_type: 杂志文章
doi:10.1016/0732-8893(87)90100-3
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journal_title:Diagnostic microbiology and infectious disease
pub_type: 杂志文章
doi:10.1016/s0732-8893(97)00174-0
更新日期:1998-01-01 00:00:00
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journal_title:Diagnostic microbiology and infectious disease
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doi:10.1016/j.diagmicrobio.2014.09.025
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journal_title:Diagnostic microbiology and infectious disease
pub_type: 杂志文章
doi:10.1016/s0732-8893(96)00197-6
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journal_title:Diagnostic microbiology and infectious disease
pub_type: 杂志文章
doi:10.1016/j.diagmicrobio.2008.10.001
更新日期:2009-02-01 00:00:00
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journal_title:Diagnostic microbiology and infectious disease
pub_type: 杂志文章
doi:10.1016/0732-8893(95)00020-b
更新日期:1995-02-01 00:00:00
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journal_title:Diagnostic microbiology and infectious disease
pub_type: 杂志文章
doi:10.1016/s0732-8893(97)00192-2
更新日期:1998-02-01 00:00:00
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journal_title:Diagnostic microbiology and infectious disease
pub_type: 杂志文章
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更新日期:2015-09-01 00:00:00
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journal_title:Diagnostic microbiology and infectious disease
pub_type: 杂志文章
doi:10.1016/j.diagmicrobio.2017.06.022
更新日期:2017-10-01 00:00:00
abstract:OBJECTIVES:Routine use of disk diffusion tests for detecting antibiotic resistance in Legionella pneumophila has not been described. The goal of this study was to determine the correlation of MIC values and inhibition zone diameter (MDcorr) in clinical L. pneumophila isolates. METHODS:Inhibition zone diameter of 183 L...
journal_title:Diagnostic microbiology and infectious disease
pub_type: 杂志文章
doi:10.1016/j.diagmicrobio.2013.03.001
更新日期:2013-07-01 00:00:00
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journal_title:Diagnostic microbiology and infectious disease
pub_type: 杂志文章
doi:10.1016/0732-8893(84)90033-6
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journal_title:Diagnostic microbiology and infectious disease
pub_type: 临床试验,杂志文章
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journal_title:Diagnostic microbiology and infectious disease
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journal_title:Diagnostic microbiology and infectious disease
pub_type: 临床试验,杂志文章,随机对照试验
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journal_title:Diagnostic microbiology and infectious disease
pub_type: 杂志文章
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journal_title:Diagnostic microbiology and infectious disease
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journal_title:Diagnostic microbiology and infectious disease
pub_type: 杂志文章
doi:10.1016/0732-8893(95)00176-x
更新日期:1995-11-01 00:00:00
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journal_title:Diagnostic microbiology and infectious disease
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journal_title:Diagnostic microbiology and infectious disease
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journal_title:Diagnostic microbiology and infectious disease
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abstract::A hydrogen-sulfide producing, citrate-positive strain of Escherichia coli isolated from urinary tract infection was found to be resistant to chloramphenicol (Cm), tetracycline (Tc), streptomycin (Sm), trimethoprim (Tmp), sulfamethoxazole (Smx), and cotrimoxazole (Tmp/Smx). The strain contained 7 plasmids of molecular ...
journal_title:Diagnostic microbiology and infectious disease
pub_type: 杂志文章
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abstract:BACKGROUND:We compared changes in antibiotics in patients diagnosed with noninvasive pneumococcal pneumonia (NPP) by pneumoccocal urinary antigen tests or respiratory cultures. METHODS:We compared patients diagnosed by pneumococcal urinary antigen tests or respiratory cultures that grew Streptococcus pneumoniae. We as...
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