National surveillance of nosocomial blood stream infection due to species of Candida other than Candida albicans: frequency of occurrence and antifungal susceptibility in the SCOPE Program. SCOPE Participant Group. Surveillance and Control of Pathogens of


:A national surveillance program of nosocomial blood stream infections (BSI) in the USA between April 1995 and June 1996 revealed that Candida was the fourth leading cause of nosocomial BSI, accounting for 8% of all infections. Forty-eight percent of 379 episodes of candidemia were due to species other than Candida albicans. The rank order of non-C. albicans species was C. glabrata (20%) > C. tropicalis (11%) > C. parapsilosis (8%) > C. krusei (5%) > other Candida spp. (4%). The species distribution varied according to geographic region, with non-C. albicans species predominating in the Northeast (54%) and Southeast (53%) regions, and C. albicans predominating in the Northwest (60%) and Southwest (70%) regions. In vitro susceptibility studies demonstrated that 95% of non-C. albicans isolates were susceptible to 5-fluorocytosine, and 84% and 75% were susceptible to fluconazole and itraconazole, respectively. Geographic variation in susceptibility to itraconazole, but not other agents, was observed. Isolates from the Northwest and Southeast regions were more frequently resistant to itraconazole (29-30%) than those from the Northeast and Southwest regions (17-18%). Molecular epidemiologic studies revealed possible nosocomial transmission (five medical centers). Continued surveillance for the presence of non-C. albicans species among hospitalized patients is recommended.


Pfaller MA,Jones RN,Messer SA,Edmond MB,Wenzel RP




Has Abstract


1998-02-01 00:00:00














  • Detection of herpes simplex virus in clinical specimens by DNA hybridization.

    abstract::An assay to detect herpes simplex virus (HSV) DNA in clinical specimens has been developed. It utilizes nucleic acid hybridization with a 32P-labeled DNA probe prepared from a fragment of HSV DNA cloned in a plasmid vector. This assay can detect 5 X 10(4) plaque-forming units of cell-free HSV and as few as four virus-...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章


    authors: Redfield DC,Richman DD,Albanil S,Oxman MN,Wahl GM

    更新日期:1983-06-01 00:00:00

  • Performance of the Gen-Probe amplified Mycobacterium tuberculosis direct test in a laboratory that infrequently isolates Mycobacterium tuberculosis.

    abstract::The performance of the Gen-Probe Mycobacterium tuberculosis direct (MTD) test was assessed in a laboratory whose specimens were derived from a population with a low prevalence (1.3%) of tuberculosis. A total of 339 specimens from 113 patients were included in the study. Nine of 10 MTD positive samples were culture pos...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章


    authors: Welch K,Brown G,Jonas V,Ferraro MJ

    更新日期:1995-07-01 00:00:00

  • Rapid diagnosis of tuberculosis by identification of Antigen 85 in mycobacterial culture system.

    abstract::The standard culture for identification of Mycobacterium tuberculosis takes a long time to perform. We introduce here a method for fast identification of M. tuberculosis in mycobacterial culture system. Antibodies to Antigen (Ag) 85 of M. tuberculosis were produced and subsequently used to develop enzyme-linked immuno...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章


    authors: Phunpae P,Chanwong S,Tayapiwatana C,Apiratmateekul N,Makeudom A,Kasinrerk W

    更新日期:2014-03-01 00:00:00

  • Bartonella quintana-induced apoptosis inhibition of human endothelial cells is associated with p38 and SAPK/JNK modulation and with stimulation of mitosis.

    abstract::Previous studies demonstrated that live Bartonella quintana often induces angioproliferative lesions in humans. It modulates endothelial cell apoptotic and inflammatory patterns, thus inducing a very early overexpression of caspase 8 and Apaf-1 and increasing mRNA production of TNF-alpha, interleukin-8, and E-selectin...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章


    authors: Liberto MC,Matera G,Lamberti AG,Barreca GS,Focà D,Quirino A,Soria MR,Focà A

    更新日期:2004-11-01 00:00:00

  • Comparison of microarray-predicted closest genomes to sequencing for poliovirus vaccine strain similarity and influenza A phylogeny.

    abstract::We evaluate sequence data from the PathChip high-density hybridization array for epidemiological interpretation of detected pathogens. For influenza A, we derive similar relative outbreak clustering in phylogenetic trees from PathChip-derived compared to classical Sanger-derived sequences. For a positive polio detecti...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章


    authors: Maurer-Stroh S,Lee CW,Patel C,Lucero M,Nohynek H,Sung WK,Murad C,Ma J,Hibberd ML,Wong CW,Simões EA

    更新日期:2016-03-01 00:00:00

  • Evaluation of two commercial microtiter cytotoxin assays for the detection of Clostridium difficile toxin B in stool specimens.

    abstract::Two commercial microtiter cytotoxin assays using a fibroblast cell line (Bartels, Baxter Diagnostics, Inc., Deerfield, IL) and an epithelial cell line (Cytotoxi Test, Advanced Clinical Diagnostics, Toledo, OH) were evaluated for their ability to detect Clostridium difficile toxin B in stool specimens. After 48 hours, ...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章


    authors: Fedorko DP,Williams EC

    更新日期:1996-09-01 00:00:00

  • Impact of AmpC overexpression on outcomes of patients with Pseudomonas aeruginosa bacteremia.

    abstract::AmpC overexpression (AmpC++) is a significant mechanism of beta-lactam resistance in Pseudomonas aeruginosa, but its impact on clinical outcomes is not well established. To examine the influence of AmpC++ on clinical outcomes of patients with P. aeruginosa bacteremia, we screened all bloodstream P. aeruginosa isolates...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章


    authors: Tam VH,Chang KT,Schilling AN,LaRocco MT,Genty LO,Garey KW

    更新日期:2009-03-01 00:00:00

  • Isolation and characterization of Helicobacter pylori recovered from gastric biopsies under anaerobic conditions.

    abstract:BACKGROUND AND AIM:Helicobacter pylori can survive long incubation periods under anaerobic conditions, and should be possible to isolate under anaerobic conditions. Our aim was to isolate H. pylori in anaerobic conditions, from gastric biopsies of H. pylori infected patients. METHODS:We enrolled 27 patients with bleed...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章


    authors: Perez-Perez GI,Van TN,Thu Huong D,Zhan G,Nguyet Anh D,Nguyet NT,Thi LT,Van Thinh N,Hong-Hanh NT

    更新日期:2016-10-01 00:00:00

  • Comparison of Etest and agar dilution for testing the activity of three macrolides against Bordetella parapertussis.

    abstract::Agar dilution and Etest using Mueller-Hinton II agar supplemented with 5% whole defibrinated horse blood were compared for testing the activities of azithromycin, clarithromycin, and erythromycin against 34 clinical isolates of the fastidious species Bordetella parapertussis. There was good overall agreement (100.0% w...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章


    authors: Hoppe JE,Tschirner T

    更新日期:1997-05-01 00:00:00

  • Comparative in vitro activity of cefoxitin, cefotaxime alone, and in combination with desacetylcefotaxime against the Bacteroides species.

    abstract::The agar dilution method was used to determine the inhibitory activity of cefotaxime (CTX) alone, desacetylcefotaxime (dCTX) alone, CTX plus dCTX, and cefoxitin against 74 clinical isolates of the Bacteroides species recovered from diabetic patients with foot ulcers. The study concluded that the addition of dCTX to CT...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章


    authors: Canawati HN

    更新日期:1989-01-01 00:00:00

  • Direct detection and amplification of Helicobacter pylori ribosomal 16S gene segments from gastric endoscopic biopsies.

    abstract::Helicobacter pylori is an organism thought to play an important causative role in gastritis and peptic ulcer diseases. We have designed an RNA dot blot assay for the detection of H. pylori, using as probe a synthetic oligonucleotide complementary to its 16S rRNA. We have also used oligonucleotide primers, complementar...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章


    authors: Hoshina S,Kahn SM,Jiang W,Green PH,Neu HC,Chin N,Morotomi M,LoGerfo P,Weinstein IB

    更新日期:1990-11-01 00:00:00

  • Clinical evaluation of the improved streptex method for grouping streptococci.

    abstract::The improved Streptex method for serogrouping streptococci incorporates a new extraction enzyme and a simplified procedure requiring no centrifugation. A total of 114 clinical isolates of beta-hemolytic streptococci were serogrouped from primary plates, isolation plates, and Todd-Hewitt broth cultures using this syste...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章


    authors: Bixler-Forell E,Martin WJ,Moody MD

    更新日期:1984-04-01 00:00:00

  • The effect of fecal turbidity on norovirus detection by reverse transcriptase polymerase chain reaction.

    abstract::A 10-min fecal preparation results in greater specimen turbidity than a 45-min protocol, but reverse transcriptase polymerase chain reaction (RT-PCR) norovirus test sensitivity is essentially the same. Feces processed so that particle size does not exceed approximately 560 nm do not display greater norovirus RT-PCR in...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章


    authors: Witlox KJ,Karapanagiotidis T,Bruggink LD,Marshall JA

    更新日期:2010-02-01 00:00:00

  • A study on producing monoclonal antibody with one diagnostic marker screened electrophoretically from the urine of individuals infected with Schistosoma japonicum.

    abstract::One diagnostic marker (a glycoprotein with 30kDa) from the urine of individuals infected with S. japonicum was screened with electrophoresis, and used as antigen to produce McAbs. Two lines of McAbs, named NP56 and NP54,were obtained. McAb NP56 was of better immunoreactivity and its immunoglobulin isotype was IgG(2b.)...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章


    authors: Zhu C,Tian H,Lu L,Li Y,Feng Z,Ma L,Guan X

    更新日期:2000-12-01 00:00:00

  • Use of surrogate antimicrobial agents to predict susceptibility to ertapenem.

    abstract::Broth or agar dilution susceptibility test results for Enterobacteriaceae (11,775 strains), anaerobes (2888 strains), staphylococci (2206 strains), Haemophilus spp. (840 strains), group A streptococci (280 strains), group B streptococci (269 strains), Streptococcus pneumoniae (709 strains), and 160 other streptococci ...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章


    authors: Friedland IR,Isaacs R,Mixson LA,Motyl M,Woods GL

    更新日期:2002-05-01 00:00:00

  • Effects of feeding lactobacillus GG on lethal irradiation in mice.

    abstract::Mice exposed to 1400 rads of total body irradiation experienced 80%-100% mortality in 2 wk. Bacteremia was demonstrated in all dead animals. Feeding Lactobacillus GG strain reduced Pseudomonas bacteremia and prolonged survival time in animals colonized with this organism. In animals not colonized with Pseudomonas, fee...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章


    authors: Dong MY,Chang TW,Gorbach SL

    更新日期:1987-05-01 00:00:00

  • Emergence of metallo-β-lactamases in Enterobacteriaceae from Argentina.

    abstract::Carbapenem susceptibility in Enterobacteriaceae (M9921, M9959) revealed the presence of MBLs bla(VIM-2) (M9959) and bla(IMP-8) (M9921), both as first cassettes of class-1-integrons. ESBL bla(PER-2) was detected in both strains and M9921 also harboured qnrB10, aac(6')-Ib and aac(6')-Ib-cr. This is the first report of M...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章


    authors: Gomez S,Rapoport M,Togneri A,Viegas-Caetano J,Faccone D,Corso A,Petroni A,Pasteran F

    更新日期:2011-01-01 00:00:00

  • In vitro activity of antituberculous agents against Mycobacterium tuberculosis isolates from Bogota, DC (Colombia) evaluated by the ETest.

    abstract::Tuberculosis tests for antimicrobial susceptibility takes weeks. However, delayed therapy, can compromise the patient, as well as lead to an increase in disease incidence. Among infectious diseases, tuberculosis continues to be a leading cause of death in the world. The E-test is a new concept for Minimal Inhibitory C...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章


    authors: Sánchez L,Londoño D,Arango AI,Mattar S

    更新日期:1999-10-01 00:00:00

  • Carbapenem therapy for bacteremia due to extended-spectrum β-lactamase-producing Escherichia coli or Klebsiella pneumoniae.

    abstract::For 244 patients with bacteremia due to extended-spectrum β-lactamase (ESBL)-producing Escherichia coli or Klebsiella pneumoniae treated by ertapenem (73, 29.9%) or either imipenem or meropenem (171, 70.1%), the therapeutic efficacy was evaluated. Ertapenem therapy was effective for patients with ESBL-producing E. col...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章


    authors: Lee NY,Huang WH,Tsui KC,Hsueh PR,Ko WC

    更新日期:2011-05-01 00:00:00

  • Bacterial pathogens isolated from patients with skin and soft tissue infections: frequency of occurrence and antimicrobial susceptibility patterns from the SENTRY Antimicrobial Surveillance Program (United States and Canada, 1997). SENTRY Study Group (Nor

    abstract::As part of the SENTRY Antimicrobial Surveillance Program, 1562 bacterial isolates were recovered from hospitalized patients with skin and soft tissue infections (SSTIs) in 30 United States (U.S.) and 8 Canadian medical centers between October and December, 1997. The overall rank order of recovery of the six most commo...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章,多中心研究


    authors: Doern GV,Jones RN,Pfaller MA,Kugler KC,Beach ML

    更新日期:1999-05-01 00:00:00

  • Evaluation of the in vitro activity of cefepime compared to other broad-spectrum cephalosporins against clinical isolates from eighteen Brazilian hospitals by using the Etest.

    abstract::The in vitro activity of cefepime was compared to that of ceftazidime, ceftriaxone, and cefotaxime in a multicenter study involving 10 clinical microbiology laboratories and clinical isolates from 18 Brazilian hospitals from 7 cities (4 states). A total of 982 isolates consecutively collected between December 1995 and...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章


    authors: Sader HS,Mimiça I,Rossi F,Zoccoli C,Montelli AC,Sampaio JL,Segura AJ,Magalhães M,Nowakonski A,Mendes CM

    更新日期:1997-06-01 00:00:00

  • Multi-laboratory evaluation of the rapid genoserotyping array (SGSA) for the identification of Salmonella serovars.

    abstract::Salmonella serotyping is an essential first step for identification of isolates associated with disease outbreaks. The Salmonella genoserotyping array (SGSA) is a microarray-based alternative to standard serotyping designed to rapidly identify 57 of the most commonly reported serovars through detection of the genes en...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章


    authors: Yoshida C,Lingohr EJ,Trognitz F,MacLaren N,Rosano A,Murphy SA,Villegas A,Polt M,Franklin K,Kostic T,OIE Reference Laboratory for Salmonellosis.,Austrian Agency for Health and Food Safety.,Kropinski AM,Card RM

    更新日期:2014-11-01 00:00:00

  • Evaluation of the fully automated AIX1000 rapid plasma reagin system compared to a manual plasma reagin testing method for the diagnosis of syphilis.

    abstract::The analytical performance of the FDA-cleared AIX1000 automated RPR testing platform was evaluated in comparison to manual RPR card testing. Eight hundred thirty-three patient serum samples were analyzed, 87 samples were positive by the AIX1000, 108 were positive by the manual test method; overall agreement between me...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章


    authors: Pyden A,Kang AD,Amato S,Dutta S,Berg G,Riedel S

    更新日期:2020-08-01 00:00:00

  • Susceptibility testing of Clostridium difficile against metronidazole and vancomycin by disk diffusion and Etest.

    abstract::A prospective study on the susceptibility of Clostridium difficile to metronidazole and vancomycin using the Etest and disk diffusion test was performed over a 6-month period. One hundred strains were tested; one strain was highly resistant to metronidazole (MIC = 64 micrograms/mL). The zone size of inhibition by the ...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章


    authors: Wong SS,Woo PC,Luk WK,Yuen KY

    更新日期:1999-05-01 00:00:00

  • Characterization of extended-spectrum beta-lactamases and antimicrobial resistance of Klebsiella pneumoniae in intra-abdominal infection isolates in Latin America, 2008-2012. Results of the Study for Monitoring Antimicrobial Resistance Trends.

    abstract::The Study for Monitoring Antimicrobial Resistance Trends has monitored the in vitro activity of several recommended antimicrobials used in the management of intra-abdominal infections (IAIs) globally since 2002. In this report, we document the changing susceptibility patterns to recommended antimicrobials in Klebsiell...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章


    authors: Kazmierczak KM,Lob SH,Hoban DJ,Hackel MA,Badal RE,Bouchillon SK

    更新日期:2015-07-01 00:00:00

  • Evaluation of CPS ID 2 chromogenic agar as a single medium for urine culture.

    abstract::The CPS ID 2 (CPS) chromogenic agar was compared to routine media for use in the isolation, enumeration, identification, and susceptibility testing of bacteria recovered from urine specimens. Of 487 urine specimens, 318 were culture negative, 12 were positive on CPS only, 16 positive on routine only, and 141 positive ...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章


    authors: Reisner BS,Austin EF

    更新日期:1997-07-01 00:00:00

  • Reproducibility of gemifloxacin and comparison fluoroquinolone MIC results using Sensititre commercial dry-form panels.

    abstract::This study examined the ability of commercial dry-form broth microdilution panels (Sensititre, TREK Diagnostics, Cleveland, OH) to produce accurate minimum inhibitory concentration (MIC) results for gemifloxacin, a new fluoroquinolone. Reproducibility for gemifloxacin was 100.0% for on-scale values within +/-1 log2 di...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章


    authors: Ross JE,Sader HS,Fritsche TR,Jones RN

    更新日期:2005-03-01 00:00:00

  • In vitro comparison of cefoperazone/sulbactam with selected antimicrobials against 300 bacteroides isolates. Inhibitory activity and time-kill kinetic studies.

    abstract::The susceptibilities of 258 Bacteroides fragilis group isolates and 42 other Bacteroides species isolates against cefoperazone, cefoperazone/sulbactam (2:1 ratio) and selected other antimicrobials were determined by broth microdilution method. All isolates were susceptible to cefoperazone/sulbactam, ampicillin/sulbact...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章


    authors: Gelfand MS,Grogan JT,Haas MJ

    更新日期:1989-09-01 00:00:00

  • Genetic mutations in linezolid-resistant Mycobacterium avium complex and Mycobacterium abscessus clinical isolates.

    abstract::There are no studies evaluating the mechanisms driving linezolid resistance in nontuberculous mycobacteria. The novel mutations G2599A and A2137T in the 23S rRNA gene and mutations A439G and G443A in the rplD gene associated with linezolid resistance were identified in linezolid-resistant M. avium complex isolates. ...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章


    authors: Kim SY,Jhun BW,Moon SM,Jeon K,Kwon OJ,Huh HJ,Lee NY,Shin SJ,Daley CL,Koh WJ

    更新日期:2019-05-01 00:00:00

  • Molecular types and antimicrobial susceptibility patterns of Clostridium difficile isolates in different epidemiological settings in a tertiary care center in Israel.

    abstract::The aims of this prospective study were to examine the correlation between the molecular types and the antimicrobial susceptibility patterns of Clostridium difficile isolates with the source of acquisition and the occurrence of C. difficile infections (CDI) in a tertiary center in Israel. All available isolates from c...

    journal_title:Diagnostic microbiology and infectious disease

    pub_type: 杂志文章


    authors: Miller-Roll T,Na'amnih W,Cohen D,Carmeli Y,Adler A

    更新日期:2016-12-01 00:00:00