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Pyrosequencing-based approach for rapid detection of rifampin-resistant Mycobacterium tuberculosis.

Abstract：

:Rifampin resistance in Mycobacterium tuberculosis could be determined within 2 h by using pyrosequencing-based approach. Pyrosequencing results of rifampin-resistant (n = 21) and rifampin-susceptible (n = 20) M. tuberculosis isolates were concordant with those based on drug susceptibility testing and conventional DNA sequencing. Results showed pyrosequencing-based approach is a rapid, sensitive, and efficient detection method of rifampin-resistant M. tuberculosis.

journal_name

Diagn Microbiol Infect Dis

journal_title

Diagnostic microbiology and infectious disease

authors

Zhao JR,Bai YJ,Zhang QH,Wang Y,Luo M,Yan XJ

doi

10.1016/j.diagmicrobio.2004.10.001

subject

Has Abstract

pub_date

2005-02-01 00:00:00

pages

135-7

issue

2

eissn

0732-8893

issn

1879-0070

pii

S0732-8893(04)00205-6

journal_volume

51

pub_type

杂志文章

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