Structural and transcriptional analysis of human papillomavirus type 16 sequences in cervical carcinoma cell lines.

abstract：:Rift Valley fever virus strain MP-12 was generated by serial plaque passages of parental strain ZH548 12 times in MRC-5 cells in the presence of a chemical mutagen, 5-fluorouracil. As a result, MP-12 encoded 4, 9, and 10 mutations in the S, M, and L segments, respectively. Among them, mutations in the M and L segments...

journal_title：Journal of virology

authors： Lokugamage N,Freiberg AN,Morrill JC,Ikegami T

更新日期：2012-12-01 00:00:00

abstract：:The Cp promoter of Epstein-Barr virus (EBV) directs most transcription of the EBNA genes in lymphoblastoid cell lines. The functions of two control regions in the Cp promoter have been studied by construction of recombinant EBV strains containing specific mutations in these elements. Mutation of the RBP-Jk (CBF1) bind...

journal_title：Journal of virology

authors： Evans TJ,Farrell PJ,Swaminathan S

更新日期：1996-03-01 00:00:00

abstract：:The goose parvovirus (GPV) Rep 1 and Rep 2 proteins are encoded by P9-generated mRNAs that are either unspliced or spliced within the rep gene region, respectively. These mRNAs are present in an approximately equal ratio. The translation of Rep 1 was initiated from the first AUG in unspliced P9-generated mRNA; however...

journal_title：Journal of virology

authors： Li L,Qiu J,Pintel DJ

更新日期：2009-10-01 00:00:00

abstract：UNLABELLED:Venezuelan equine encephalitis virus (VEEV) is an important human and animal pathogen, for which no safe and efficient vaccines or therapeutic means have been developed. Viral particle assembly and budding processes represent potential targets for therapeutic intervention. However, our understanding of the m...

journal_title：Journal of virology

authors： Reynaud JM,Lulla V,Kim DY,Frolova EI,Frolov I

更新日期：2015-12-09 00:00:00

abstract：:Human cytomegalovirus (HCMV) protein pUL38 has been shown to prevent premature cell death by antagonizing cellular stress responses; however, the underlying mechanism remains unknown. In this study, we identified the host protein ubiquitin-specific protease 24 (USP24) as an interaction partner of pUL38. Mutagenesis an...

journal_title：Journal of virology

authors： Sun Y,Bao Q,Xuan B,Xu W,Pan D,Li Q,Qian Z

更新日期：2018-06-13 00:00:00

abstract：:The major inducible 70-kDa heat shock protein (hsp70) is host protective in a mouse model of measles virus (MeV) brain infection. Transgenic constitutive expression of hsp70 in neurons, the primary target of MeV infection, abrogates neurovirulence in neonatal H-2(d) congenic C57BL/6 mice. A significant level of protec...

journal_title：Journal of virology

authors： Kim MY,Shu Y,Carsillo T,Zhang J,Yu L,Peterson C,Longhi S,Girod S,Niewiesk S,Oglesbee M

更新日期：2013-01-01 00:00:00

abstract：:Kaposi's sarcoma (KS) and primary effusion lymphoma (PEL) cells are predominantly infected with latent Kaposi's sarcoma-associated herpesvirus (KSHV), presenting a barrier to the destruction of tumor cells. Latent KSHV can be reactivated to undergo lytic replication. Here we report that in PEL cells, oxidative stress ...

journal_title：Journal of virology

authors： Li X,Feng J,Sun R

更新日期：2011-01-01 00:00:00

abstract：:Radioimmunoassays were developed for the 19,000, 15,000, and 12,000 molecular weight polypeptides of avian myeloblastosis virus and for the 19,000 and 12,000 polypeptides of RAV-0, a subgroup E avian tumor virus. Each polypeptide was shown to possess both group- and type-specific antigenic determinants, in contrast to...

journal_title：Journal of virology

authors： Stephenson JR,Smith EJ,Crittenden LB,Aaronson SA

更新日期：1975-07-01 00:00:00

abstract：:Stress signaling from mitochondria and the endoplasmic reticulum (ER) leads to the induction of the proapoptotic transcription factor CHOP/GADD153. Many viruses use the ER as a site of replication and/or envelopment, and this activity can lead to the activation of ER stress and apoptosis. African swine fever virus (AS...

journal_title：Journal of virology

authors： Netherton CL,Parsley JC,Wileman T

更新日期：2004-10-01 00:00:00

abstract：:Picornaviruses rearrange cellular membranes to form cytosolic replication sites. In the case of poliovirus and several other picornaviruses, these membranes are derived from subversion of the cellular autophagy pathway. We also reported observation of autophagosome-like structures during infection by two human rhinovi...

journal_title：Journal of virology

authors： Klein KA,Jackson WT

更新日期：2011-09-01 00:00:00

abstract：:Canine distemper virus (CDV) uses signaling lymphocyte activation molecule (SLAM), expressed on immune cells, as a receptor. However, epithelial and neural cells are also affected by CDV in vivo. Wild-type CDV strains showed efficient replication with syncytia in Vero cells expressing dog nectin4, and the infection wa...

journal_title：Journal of virology

authors： Pratakpiriya W,Seki F,Otsuki N,Sakai K,Fukuhara H,Katamoto H,Hirai T,Maenaka K,Techangamsuwan S,Lan NT,Takeda M,Yamaguchi R

更新日期：2012-09-01 00:00:00

abstract：:Cytotoxic T-lymphocyte (CTL) responses are crucial for the control of immunodeficiency virus replication. Possible involvement of a dominant single epitope-specific CTL in control of viral replication has recently been indicated in preclinical AIDS vaccine trials, but it has remained unclear if multiple epitope-specif...

journal_title：Journal of virology

authors： Kawada M,Igarashi H,Takeda A,Tsukamoto T,Yamamoto H,Dohki S,Takiguchi M,Matano T

更新日期：2006-02-01 00:00:00

abstract：:We have recently described an intracellular protein, p21, in nonproducer cells transformed by either the Kirsten (Ki-MSV) or Harvey (Ha-MSV) strain of murine sarcoma virus (Shih et al., Virology, in press). The p21 is phosphorylated and has been shown to be coded for by either Ki-MSV or Ha-MSV. In this report, we comp...

journal_title：Journal of virology

authors： Shih TY,Weeks MO,Young HA,Scolnick EM

更新日期：1979-08-01 00:00:00

abstract：:We have evaluated the potential of conferring protective immunity to herpes simplex virus type 2 (HSV-2) by selectively inducing an HSV-specific CD8(+) cytotoxic T-lymphocyte (CTL) response directed against a single major histocompatibility complex class I-restricted CTL recognition epitope. We generated a recombinant...

journal_title：Journal of virology

authors： Blaney JE Jr,Nobusawa E,Brehm MA,Bonneau RH,Mylin LM,Fu TM,Kawaoka Y,Tevethia SS

更新日期：1998-12-01 00:00:00

abstract：:New zonal centrifuges can conveniently process as much as five orders of magnitude (10(5)) greater sample volumes than conventional swinging-bucket rotors. The continuous-sample-flow-with-banding versions may be used in series with ancillary purification procedures. Here we have studied the combined process: absorptio...

journal_title：Journal of virology

authors： Reimer CB,Baker RS,Van Frank RM,Newlin TE,Cline GB,Anderson NG

更新日期：1967-12-01 00:00:00

abstract：:Experiments with St. Louis encephalitis (SLE) virus have shown that neutral red enhances the plaque size in duck embryo cell cultures. This may represent a new method for genetic studies of SLE virus population. In a mosquito pool specimen NR(+) and NR(-) particles were demonstrated. By intracerebral passage in mice, ...

journal_title：Journal of virology

authors： Marcovici M,Prier JE

更新日期：1968-03-01 00:00:00

abstract：:The roles of intracellular naked (INV), cell-associated enveloped (CEV), and extracellular enveloped (EEV) forms of vaccinia virus in cell-to-cell and longer-range spread were investigated by using two closely related strains of vaccinia virus, WR and IHD-J. We confirmed previous results that WR and IHD-J produced sim...

journal_title：Journal of virology

authors： Blasco R,Moss B

更新日期：1992-07-01 00:00:00

abstract：:Previous studies showed that the amino-terminal domain of Rous sarcoma virus p60v-src involved in myristylation and membrane association of the protein is required for morphological transformation and anchorage independence. Analysis of src delection mutants revealed that the amino-terminal one-third of p60v-src, incl...

journal_title：Journal of virology

authors： Calothy G,Laugier D,Cross FR,Jove R,Hanafusa T,Hanafusa H

更新日期：1987-05-01 00:00:00

abstract：:An alternatively spliced form of c-myb exists that encodes an additional 120 amino acids in chicken and 121 amino acids in human and mouse. These amino acids are encoded by an additional exon, termed exon 9A. This exon is not present in v-myb, and proteins containing these amino acids have never been tested for oncoge...

journal_title：Journal of virology

authors： Woo CH,Sopchak L,Lipsick JS

更新日期：1998-08-01 00:00:00

abstract：:Interferon (IFN) signal transduction involves interferon regulatory factors (IRF). Kaposi's sarcoma-associated herpesvirus (KSHV) encodes four IRF homologues: viral IRF 1 (vIRF-1) to vIRF-4. Previous functional studies revealed that the first exon of vIRF-2 inhibited alpha/beta interferon (IFN-alpha/beta) signaling. W...

journal_title：Journal of virology

authors： Fuld S,Cunningham C,Klucher K,Davison AJ,Blackbourn DJ

更新日期：2006-03-01 00:00:00

abstract：:The synthesis of closed circular simian virus 40 (SV40) deoxyribonucleic acid (DNA) containing sequences homologous to host cell DNA depends upon the conditions under which the cells are infected. When BS-C-1 monkey cells were infected with non-plaque-purified virus at low multiplicity of infection [MOI, 0.032 plaque-...

journal_title：Journal of virology

authors： Lavi S,Winocour E

更新日期：1972-02-01 00:00:00

abstract：:The spikes of alphaviruses are composed of three copies of an E2-E1 heterodimer. The E1 protein possesses membrane fusion activity, and the E2 protein, or its precursor form, p62 (sometimes called PE2), controls this function. Both proteins are, together with the viral capsid protein, translated from a common C-p62-E1...

journal_title：Journal of virology

authors： Andersson H,Barth BU,Ekström M,Garoff H

更新日期：1997-12-01 00:00:00

abstract：:MC159 is a viral FLIP (FLICE inhibitory protein) encoded by the molluscum contagiosum virus (MCV) enabling MCV to evade antiviral immunity and to establish persistent infections in humans. Here, we show that MC159 contains a functional SH3 binding motif, which mediates avid and selective binding to SH3BP4, a signaling...

journal_title：Journal of virology

authors： Schmotz C,Uğurlu H,Vilen S,Shrestha S,Fagerlund R,Saksela K

更新日期：2019-05-01 00:00:00

abstract：:This paper reports the use of zonal ultracentrifuge techniques to conduct biophysical studies of rhinoviruses grown with WI-38 cells. Good clean-out of infectivity from rhinovirus harvests was obtained with the continuous-flow B-V and B-IX rotors. Use of the B-V rotor resulted in the successful concentration of rhinov...

journal_title：Journal of virology

authors： Gerin JL,Richter WR,Fenters JD,Holper JC

更新日期：1968-09-01 00:00:00

abstract：:Type C RNA virus(es) was readily released from primary lymphosarcoma cell cultures of WH/J rabbits after induction with halogenated pyrimidines. The virus contained an RNA-directed DNA polymerase and the p30 structural protein. The rabbit virus RNA-directed DNA polymerase and p30 protein shared antigenic homologies wi...

journal_title：Journal of virology

authors： Bedigian HG,Fox RR,Meier H

更新日期：1978-08-01 00:00:00

abstract：:The present studies explore the role of polymicrobial infection in the reactivation of Kaposi's sarcoma-associated herpesvirus (KSHV) and analyze signaling pathways activated upon this induction. We hypothesized that activation of the cellular stress-activated mitogen-activated protein kinase (MAPK) p38 pathway would ...

journal_title：Journal of virology

authors： Morris TL,Arnold RR,Webster-Cyriaque J

更新日期：2007-06-01 00:00:00

abstract：:MVL2, an enveloped double-stranded DNA mycoplasmavirus, causes a nonlytic infection of Acholeplasma laidlawii leading to the establishment of a persistent infection. Persistently infected clones were found to be resistant to superinfection by homologous virus, but could be infected by heterologous virus. Cells in a pe...

journal_title：Journal of virology

authors： Putzrath RM,Maniloff J

更新日期：1978-10-01 00:00:00

abstract：:Closed circular unintegrated DNA of the SEATO strain of gibbon ape leukemia virus (GaLV-S) was isolated from canine thymus fibroblasts after cocultivation with chronically infected bat lung fibroblasts. Restriction endonuclease HindIII cleaves GaLV-S DNA once, thus allowing isolation and cloning of HindIII-digested un...

journal_title：Journal of virology

authors： Gelmann EP,Trainor CD,Wong-Staal F,Reitz MS

更新日期：1982-10-01 00:00:00

abstract：:The hepatitis B virus (HBV) X protein (HBx) is a multifunctional regulator of cellular signal transduction and transcription pathways and has a critical role in HBV replication. Much of the cytoplasmic signal transduction activity associated with HBx expression and its stimulation of viral replication is attributable ...

journal_title：Journal of virology

authors： Bouchard MJ,Wang L,Schneider RJ

更新日期：2006-05-01 00:00:00

abstract：UNLABELLED:Virions vary in size by at least 4 orders of magnitude, yet the evolutionary forces responsible for this enormous diversity are unknown. We document a significant allometric relationship, with an exponent of approximately 1.5, between the genome length and virion volume of viruses and find that this relation...

journal_title：Journal of virology

authors： Cui J,Schlub TE,Holmes EC

更新日期：2014-06-01 00:00:00