Young Children Display Diurnal Patterns of Salivary IgA and Alpha-Amylase Expression Which Are Independent of Food Intake and Demographic Factors.

Abstract:

Background:Salivary alpha-amylase (sAA) and salivary immunoglobulin A (sIgA) have been proposed as biomarkers for research on the mucosal immune system and on stress. Expression of both sAA and sIgA has been described to follow opposing diurnal patterns. This knowledge is crucial for the interpretation of studies using these biomarkers. Aim:It was hypothesized that sAA and sIgA display diurnal patterns in children and that this is independent of food intake or demographic factors. Methods:Whole saliva was collected from 78 healthy children (15-39 months old) in the morning and evening for two random nonconsecutive days. The samples have been analysed for sAA and sIgA. The total daily energy, fat, saturated fat, protein, carbohydrate and fibre, mineral, and vitamin consumption were analysed based on the two-day weighed food records collected by the parents. Results:It was demonstrated that most young children followed the diurnal pattern when sAA increased and sIgA decreased from morning to evening. No correlation was observed between the intake of any of the nutrients and morning or evening values for both salivary proteins. The morning and evening values of sAA and sIgA did not correlate with age, sex, Asian ethnicity, and BMI of the children. Conclusion:Diurnal patterns of sAA and sIgA exist in healthy young children and are not affected by their nutrient intake, sex, Asian ethnicity, and BMI. Scientists including sIgA and sAA in their research must consider the diurnal pattern that these markers exhibit and design the study accordingly.

journal_name

Biomed Res Int

authors

Lim PW,Nambiar S,Muhardi L,Abdul Kader UH,Garssen J,Sandalova E

doi

10.1155/2019/3687416

subject

Has Abstract

pub_date

2019-01-14 00:00:00

pages

3687416

eissn

2314-6133

issn

2314-6141

journal_volume

2019

pub_type

杂志文章
  • In silico investigation of traditional Chinese medicine compounds to inhibit human histone deacetylase 2 for patients with Alzheimer's disease.

    abstract::Human histone deacetylase 2 (HDAC2) has been identified as being associated with Alzheimer's disease (AD), a neuropathic degenerative disease. In this study, we screen the world's largest Traditional Chinese Medicine (TCM) database for natural compounds that may be useful as lead compounds in the search for inhibitors...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2014/769867

    authors: Hung TC,Lee WY,Chen KB,Chan YC,Lee CC,Chen CY

    更新日期:2014-01-01 00:00:00

  • Expression of Adiponectin Receptors on Peripheral Blood Leukocytes of Hypertensive Children Is Associated with the Severity of Hypertension.

    abstract::The aim of the study was to find out whether peripheral blood leukocyte adiponectin receptors 1 and 2 (AdipoR1, AdipoR2) protein expression patterns (flow cytometry) differ between the primary hypertension children (n = 57) and healthy controls (n = 19) and if their expression levels are related to selected clinical p...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2015/742646

    authors: Gackowska L,Litwin M,Trojanek J,Eljaszewicz A,Kubiszewska I,Niemirska A,Wierzbicka A,Michalkiewicz J

    更新日期:2015-01-01 00:00:00

  • Exploring the Underlying Genetics of Craniofacial Morphology through Various Sources of Knowledge.

    abstract::The craniofacial complex is the billboard of sorts containing information about sex, health, ancestry, kinship, genes, and environment. A thorough knowledge of the genes underlying craniofacial morphology is fundamental to understanding craniofacial biology and evolution. These genes can also provide an important foun...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2016/3054578

    authors: Roosenboom J,Hens G,Mattern BC,Shriver MD,Claes P

    更新日期:2016-01-01 00:00:00

  • Adherence to Allergen Subcutaneous Immunotherapy is Increased by a Shortened Build-Up Phase: A Retrospective Study.

    abstract::Introduction. The poor long-term adherence is known to affect the efficacy of allergen immunotherapy (AIT). In the case of injection AIT (SCIT), one of the main determinants is the inconvenience for patients to undergo prolonged build-up phases. Thus, simplifying the time schedule of the induction protocol could be ef...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2020/7328469

    authors: Caruso C,Bramé B,Bagnasco D,Cocconcelli A,Ortolani V,Pravettoni V,Scarpa S,Zisa G,Passalacqua G,Colantuono S

    更新日期:2020-02-18 00:00:00

  • Duodenal Atresia: Open versus MIS Repair-Analysis of Our Experience over the Last 12 Years.

    abstract::Objective. Duodenal atresia (DA) routinely has been corrected by laparotomy and duodenoduodenostomy with excellent long-term results. We revisited the patients with DA treated in the last 12 years (2004-2016) comparing the open and the minimally invasive surgical (MIS) approach. Methods. We divided our cohort of patie...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2017/4585360

    authors: Chiarenza SF,Bucci V,Conighi ML,Zolpi E,Costa L,Fasoli L,Bleve C

    更新日期:2017-01-01 00:00:00

  • Differences in extended-spectrum beta-lactamase producing Escherichia coli virulence factor genes in the Baltic Sea region.

    abstract::The aim of this study was to compare the prevalence of different virulence factor (VF) genes in extended-spectrum beta-lactamase (ESBL) producing Escherichia coli strains isolated from the Baltic Sea region. A total of 432 strains of phenotypically ESBL positive E. coli were collected from 20 institutions located in E...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2014/427254

    authors: Lillo J,Pai K,Balode A,Makarova M,Huik K,Kõljalg S,Ivanova M,Kaftyreva L,Miciuleviciene J,Naaber P,Parv K,Pavelkovich A,Rööp T,Toompere K,Suzhaeva L,Sepp E

    更新日期:2014-01-01 00:00:00

  • Liver Stiffness Measurement in Psoriasis: Do Metabolic or Disease Factors Play the Important Role?

    abstract:BACKGROUND:An increased prevalence of metabolic syndrome including nonalcoholic fatty liver disease (NAFLD) was reported in psoriasis. NAFLD can progress to nonalcoholic steatohepatitis and fibrosis. Transient elastography (TE) is a noninvasive liver fibrosis assessment. We evaluated the prevalence of significant liver...

    journal_title:BioMed research international

    pub_type: 临床试验,杂志文章

    doi:10.1155/2016/7963972

    authors: Pongpit J,Porntharukchareon S,Kaewduang P,Promson K,Stitchantrakul W,Petraksa S,Thakkinstian A,Kositchaiwat C,Rajatanavin N,Sobhonslidsuk A

    更新日期:2016-01-01 00:00:00

  • Effect of eNOS on Ischemic Postconditioning-Induced Autophagy against Ischemia/Reperfusion Injury in Mice.

    abstract::Autophagy is involved in the development of numerous illnesses, including ischemia/reperfusion (I/R). Endothelial nitric oxide synthase (eNOS) participates in the protective effects of ischemic postconditioning (IPostC). However, it remains unclear whether eNOS-mediated autophagy serves as a critical role in IPostC in...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2019/5201014

    authors: Shao J,Miao C,Geng Z,Gu M,Wu Y,Li Q

    更新日期:2019-02-10 00:00:00

  • Sulfated Polysaccharides Isolated from Cloned Grateloupia filicina and Their Anticoagulant Activity.

    abstract::Sulfated polysaccharides (GSP) were isolated from the cloned Grateloupia filicina which was cultured in Jiaozhou Bay, Qingdao, China. The yield of GSP was 15.75%. The total sugar and sulfate were 40.90 and 19.89%, respectively. And the average molecular weight was 11.7 KDa. The results of neutral sugar analysis showed...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2015/612352

    authors: Chen X,Yang S,Wang J,Song L,Xing R,Liu S,Yu H,Li P

    更新日期:2015-01-01 00:00:00

  • Caudal Epidural Block: An Updated Review of Anatomy and Techniques.

    abstract::Caudal epidural block is a commonly used technique for surgical anesthesia in children and chronic pain management in adults. It is performed by inserting a needle through the sacral hiatus to gain entrance into the sacral epidural space. Using conventional blind technique, the failure rate of caudal epidural block in...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2017/9217145

    authors: Kao SC,Lin CS

    更新日期:2017-01-01 00:00:00

  • 1,25-Dihydroxyvitamin D₃ Promotes High Glucose-Induced M1 Macrophage Switching to M2 via the VDR-PPARγ Signaling Pathway.

    abstract::Macrophages, especially their activation state, are closely related to the progression of diabetic nephropathy. Classically activated macrophages (M1) are proinflammatory effectors, while alternatively activated macrophages (M2) exhibit anti-inflammatory properties. 1,25-Dihydroxyvitamin D3 has renoprotective roles th...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2015/157834

    authors: Zhang X,Zhou M,Guo Y,Song Z,Liu B

    更新日期:2015-01-01 00:00:00

  • Chair-based exercises for frail older people: a systematic review.

    abstract:INTRODUCTION:Frail older people are often unable to undertake high-intensity exercise programmes. Chair-based exercises (CBEs) are used as an alternative, for which health benefits are uncertain. OBJECTIVE:To examine the effects of CBE programmes for frail older people through a systematic review of existing literatur...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2013/309506

    authors: Anthony K,Robinson K,Logan P,Gordon AL,Harwood RH,Masud T

    更新日期:2013-01-01 00:00:00

  • Posttransplant Anemia as a Prognostic Factor of Mortality in Kidney-Transplant Recipients.

    abstract::Background. Findings on the association between posttransplant anemia (PTA) and mortality in posttransplant patients are scarce. This study explored whether PTA shortly after kidney transplantation (KT) predicts mortality at up to 10 years' follow-up, stratified for chronic kidney disease (CKD) stages. Methods. PTA wa...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2017/6987240

    authors: Majernikova M,Rosenberger J,Prihodova L,Jarcuskova M,Roland R,Groothoff JW,van Dijk JP

    更新日期:2017-01-01 00:00:00

  • The Role of Tc-99m DTPA Renal Dynamic Scintigraphy in Retroperitoneal Liposarcoma.

    abstract:Purpose:Technetium-99m diethylene triamine pentaacetic acid (Tc-99m DTPA) renal dynamic scintigraphy is a widely used imaging technique that evaluates renal function of patients with extrarenal abnormalities, but its clinical value in potentially offering us information on proliferation of liposarcoma has not yet been ...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2020/9765162

    authors: Wang Y,Li M,Dai S,Li Y

    更新日期:2020-02-22 00:00:00

  • Corrigendum to "Tabu Search and Machine-Learning Classification of Benign and Malignant Proliferative Breast Lesions".

    abstract::[This corrects the article DOI: 10.1155/2020/4671349.]. ...

    journal_title:BioMed research international

    pub_type: 杂志文章,已发布勘误

    doi:10.1155/2020/7638969

    authors: Dhahri H,Rahmany I,Mahmood A,Al Maghayreh E,Elkilani W

    更新日期:2020-06-30 00:00:00

  • A Prospective Randomized Study of Brain Tissue Oxygen Pressure-Guided Management in Moderate and Severe Traumatic Brain Injury Patients.

    abstract::The purpose of this study was to compare the effect of PbtO2-guided therapy with traditional intracranial pressure- (ICP-) guided treatment on the management of cerebral variables, therapeutic interventions, survival rates, and neurological outcomes of moderate and severe traumatic brain injury (TBI) patients. From 20...

    journal_title:BioMed research international

    pub_type: 杂志文章,随机对照试验

    doi:10.1155/2015/529580

    authors: Lin CM,Lin MC,Huang SJ,Chang CK,Chao DP,Lui TN,Ma HI,Liu MY,Chung WY,Shih YH,Tsai SH,Chiou HY,Lin MR,Jen SL,Wei L,Wu CC,Lin EY,Liao KH,Chiang YH,Chiu WT,Lin JW

    更新日期:2015-01-01 00:00:00

  • Aerobic Interval Training Regulated SIRT3 Attenuates High-Fat-Diet-Associated Cognitive Dysfunction.

    abstract::Cognitive dysfunction is an important complicated disease in obesity. Exercise ameliorates obesity and the related cognitive dysfunction. However, the underlying mechanism is still unclear. In this study, we investigated whether aerobic interval training (AIT) could attenuate high-fat-diet- (HFD-) associated cognitive...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2018/2708491

    authors: Shi Z,Li C,Yin Y,Yang Z,Xue H,Mu N,Wang Y,Liu M,Ma H

    更新日期:2018-03-22 00:00:00

  • Cholesterol Degradation and Production of Extracellular Cholesterol Oxidase from Bacillus pumilus W1 and Serratia marcescens W8.

    abstract::Cholesterol is a waxy substance present in all types of the body cells. The presence of higher concentration of low density lipoprotein (LDL) is characterized by abnormal cholesterol level and is associated with cardiovascular diseases which lead to the development of atheroma in arteries known as atherosclerosis. The...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2019/1359528

    authors: Wali H,Rehman FU,Umar A,Ahmed S

    更新日期:2019-04-28 00:00:00

  • Optimization of dairy sludge for growth of Rhizobium cells.

    abstract::In this study dairy sludge was evaluated as an alternative cultivation medium for Rhizobium. Growth of bacterial strains at different concentrations of Dairy sludge was monitored. Maximum growth of all strains was observed at 60% Dairy sludge concentration. At 60% optical density (OD) values are 0.804 for Rhizobium tr...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2013/845264

    authors: Singh AK,Singh G,Gautam D,Bedi MK

    更新日期:2013-01-01 00:00:00

  • Hemodynamic and tubular changes induced by contrast media.

    abstract::The incidence of acute kidney injury induced by contrast media (CI-AKI) is the third cause of AKI in hospitalized patients. Contrast media cause relevant alterations both in renal hemodynamics and in renal tubular cell function that lead to CI-AKI. The vasoconstriction of intrarenal vasculature is the main hemodynamic...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2014/578974

    authors: Caiazza A,Russo L,Sabbatini M,Russo D

    更新日期:2014-01-01 00:00:00

  • Sexual enhancement products for sale online: raising awareness of the psychoactive effects of yohimbine, maca, horny goat weed, and Ginkgo biloba.

    abstract:INTRODUCTION:The use of unlicensed food and herbal supplements to enhance sexual functions is drastically increasing. This phenomenon, combined with the availability of these products over the Internet, represents a challenge from a clinical and a public health perspective. METHODS:A comprehensive multilingual assessm...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2014/841798

    authors: Corazza O,Martinotti G,Santacroce R,Chillemi E,Di Giannantonio M,Schifano F,Cellek S

    更新日期:2014-01-01 00:00:00

  • Effects of Platelet-Rich Plasma on Proliferation, Viability, and Odontogenic Differentiation of Neural Crest Stem-Like Cells Derived from Human Dental Apical Papilla.

    abstract:Objective:This study is aimed at evaluating the effects of platelet-rich plasma (PRP) on proliferation, viability, and odontogenic differentiation of neural crest stem-like cells (NCSCs) derived from human dental apical papilla. Materials and Methods:Cells from apical papillae were obtained and then induced to form ne...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2020/4671989

    authors: Li J,Xiang L,Guan C,Yang X,Hu X,Zhang X,Zhang W

    更新日期:2020-05-09 00:00:00

  • Tumor Take Rate Optimization for Colorectal Carcinoma Patient-Derived Xenograft Models.

    abstract::Background. For development of individualized treatment on a routine basis, transfer of patients' tumor tissue in a xenograft model (i.e., generation of patient-derived xenografts (PDX)) is desirable for molecular, biochemical, or functional analyses. Drawbacks are dissatisfactory tumor take rates, the necessity of fa...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2016/1715053

    authors: Gock M,Kühn F,Mullins CS,Krohn M,Prall F,Klar E,Linnebacher M

    更新日期:2016-01-01 00:00:00

  • Antiepileptic Drug Management in Acute Ischemic Stroke: Are Vascular Neurologists Utilizing Electroencephalograms? An Observational Cohort Study.

    abstract:Introduction:This study examines the utility of electroencephalography (EEG) in clinical decision making in acute ischemic stroke (AIS) patients in regards to the prescription of antiseizure medications. Methods:Patients were grouped as having positive EEG (+) for epileptiform activity or negative EEG (-). These studi...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2020/6250531

    authors: Rao R,Monlezun DJ,Kimbrough T,Burkett BJ,Samai A,Martin-Schild S

    更新日期:2020-12-19 00:00:00

  • The dnd RNA Identifies Germ Cell Origin and Migration in Olive Flounder (Paralichthys olivaceus).

    abstract::The present study obtained a germ cell-specific marker dead end (dnd) in olive flounder (Paralichthys olivaceus) named Podnd. The tissue-specific expressions of Podnd transcripts were present in testis and ovary but were not detectable in other somatic tissues detected. SISH showed that Podnd expressed only in germ ce...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2015/428591

    authors: Wang X,Liu Q,Xiao Y,Yang Y,Wang Y,Song Z,You F,An H,Xiao Z,Xu S,Ma D,Li J

    更新日期:2015-01-01 00:00:00

  • A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population.

    abstract::Many topical agents are available for treating the acute phase of acne; however, few agents have been proven beneficial during the maintenance phase. Objective. To evaluate the efficacy and safety of moisturizer containing licochalcone A, 1,2-decanediol, L-carnitine, and salicylic acid during the maintenance phase of ...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2020/2857812

    authors: Kulthanan K,Trakanwittayarak S,Tuchinda P,Chularojanamontri L,Limphoka P,Varothai S

    更新日期:2020-10-16 00:00:00

  • Two-dimensional PCA highlights the differentiated antitumor and antimicrobial activity of methanolic and aqueous extracts of Laurus nobilis L. from different origins.

    abstract::Natural matrices are important sources of new antitumor and antimicrobial compounds. Species such as Laurus nobilis L. (laurel) might be used for this purpose, considering its medicinal properties. Herein, in vitro activity against human tumor cell lines, bacteria, and fungi was evaluated in enriched phenolic extracts...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2014/520464

    authors: Dias MI,Barreira JC,Calhelha RC,Queiroz MJ,Oliveira MB,Soković M,Ferreira IC

    更新日期:2014-01-01 00:00:00

  • Testing for the endogenous nature between women's empowerment and antenatal health care utilization: evidence from a cross-sectional study in Egypt.

    abstract::Women's relative lack of decision-making power and their unequal access to employment, finances, education, basic health care, and other resources are considered to be the root causes of their ill-health and that of their children. The main purpose of this paper is to examine the interactive relation between women's e...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2014/403402

    authors: Zaky HH,Armanious DM,Hussein MA

    更新日期:2014-01-01 00:00:00

  • Exopolysaccharide from Ganoderma applanatum as a promising bioactive compound with cytostatic and antibacterial properties.

    abstract::A new exopolysaccharide preparation isolated from stationary cultures of the white rot fungus Ganoderma applanatum (GpEPS) was tested in terms of its bioactive properties including its cytotoxic and immunostimulatory effect. The results indicate that the tested GpEPS (at concentrations above 22.85 µg/mL and 228.5 µg/m...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2014/743812

    authors: Osińska-Jaroszuk M,Jaszek M,Mizerska-Dudka M,Błachowicz A,Rejczak TP,Janusz G,Wydrych J,Polak J,Jarosz-Wilkołazka A,Kandefer-Szerszeń M

    更新日期:2014-01-01 00:00:00

  • Increased Risk of Coronary Artery Disease in People with a Previous Diagnosis of Carpal Tunnel Syndrome: A Nationwide Retrospective Population-Based Case-Control Study.

    abstract:Background:Existing literature suggests that an association exists between coronary artery disease (CAD) and carpal tunnel syndrome (CTS), but few researchers have explored whether CTS is a risk for CAD. Materials and Methods:This large case-control study explored the association between CTS and CAD, using health insu...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2019/3171925

    authors: Chang YC,Chiang JH,Lay IS,Lee YC

    更新日期:2019-03-03 00:00:00