Abstract:
OBJECTIVE:To develop a model to predict cesarean-associated red blood cell transfusion. STUDY DESIGN:Secondary analysis of all cesarean deliveries in the Maternal-Fetal Medicine Units Network Cesarean Registry. Using a split-sample technique, the derivation group was used to identify associated factors and build predictive models, and the validation group was used to estimate classification errors and determine test characteristics. Using factors available at the time of cesarean, we developed a multivariable logistic regression prediction model. RESULTS:A total of 59,468 women were split evenly and randomly into the derivation and validation groups. The overall rate of transfusion was 2.7%. The area under the receiver operating characteristic curve for the derivation and validation groups were 0.82 (95% confidence interval [CI]: 0.80-0.84) and 0.84 (95% CI: 0.82-0.85), respectively (p = 0.16). The strongest predictors of transfusion were placenta previa (odds ratio [OR]: 7.06, 95% CI: 5.19-9.61) and eclampsia/Hemolysis Elevated Liver Enzymes Low Platelets syndrome (OR: 5.67, 95% CI: 3.77-8.51). In the validation group, the model had a sensitivity, specificity, positive, and negative predictive values of 55.8, 91.5, 16.2, and 98.6%, respectively. Overall, 90.5% of patients were correctly classified. CONCLUSION:A regression model incorporating variables available at the time of cesarean accurately predicts the need for intra- or postoperative transfusion.
journal_name
Am J Perinatoljournal_title
American journal of perinatologyauthors
Albright CM,Spillane TE,Hughes BL,Rouse DJdoi
10.1055/s-0039-1678604subject
Has Abstractpub_date
2019-07-01 00:00:00pages
879-885issue
9eissn
0735-1631issn
1098-8785journal_volume
36pub_type
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journal_title:American journal of perinatology
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journal_title:American journal of perinatology
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journal_title:American journal of perinatology
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journal_title:American journal of perinatology
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journal_title:American journal of perinatology
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journal_title:American journal of perinatology
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journal_title:American journal of perinatology
pub_type: 杂志文章,多中心研究,随机对照试验
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journal_title:American journal of perinatology
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:2004-02-01 00:00:00
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pub_type: 杂志文章,随机对照试验
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更新日期:2015-03-01 00:00:00
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journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-999341
更新日期:1991-01-01 00:00:00
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更新日期:2018-08-01 00:00:00
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journal_title:American journal of perinatology
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pub_type: 杂志文章
doi:10.1055/s-0034-1370347
更新日期:2014-11-01 00:00:00
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journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-999866
更新日期:1986-07-01 00:00:00
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journal_title:American journal of perinatology
pub_type: 杂志文章
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更新日期:2014-09-01 00:00:00
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journal_title:American journal of perinatology
pub_type: 杂志文章,多中心研究,随机对照试验
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更新日期:2019-12-01 00:00:00
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pub_type: 杂志文章,随机对照试验
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pub_type: 杂志文章,评审
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journal_title:American journal of perinatology
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更新日期:2007-11-01 00:00:00
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journal_title:American journal of perinatology
pub_type: 杂志文章
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更新日期:2016-05-01 00:00:00
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journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-994064
更新日期:1998-01-01 00:00:00
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journal_title:American journal of perinatology
pub_type: 杂志文章
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更新日期:2012-04-01 00:00:00
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journal_title:American journal of perinatology
pub_type: 杂志文章
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更新日期:2019-07-01 00:00:00
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pub_type: 杂志文章
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更新日期:2020-01-01 00:00:00
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journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-999581
更新日期:1989-04-01 00:00:00
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journal_title:American journal of perinatology
pub_type: 杂志文章,评审
doi:10.1055/s-2007-999616
更新日期:1989-07-01 00:00:00