Abstract：
OBJECTIVE:Postpartum higher-dose oxytocin (80 U) compared with lower dose (10 U) given in 500 mL over 1 hour does not decrease postpartum hemorrhage (PPH) requiring treatment, but reduces the risk of hematocrit decline ≥ 6% among women delivering vaginally. Our objective was to evaluate whether the duration of administration of oxytocin influences outcomes. STUDY DESIGN:We compared a cohort receiving a postpartum oxytocin infusion of 80 U/500 mL over 1 hour to a concurrent cohort of women receiving 80 U/500 mL over 8 hours. The primary outcome was any treatment of PPH (uterotonics, blood transfusion, tamponade, and surgery). Secondary outcomes included pre- to postdelivery median hematocrit change and hematocrit decline ≥ 6%. RESULTS:There were 653 and 676 women identified in the 1- and 8-hour cohorts, respectively. There was no difference in PPH requiring any treatment between the 1- and 8-hour cohorts (6 vs. 6%, p = 0.70). There were no differences in individual treatment components including blood transfusion (p = 0.75). Median hematocrit decline (p = 0.02) was lower in the 8-hour cohort, but there was no difference in frequency of hematocrit decline ≥ 6% (p = 0.15). Results were unchanged by multivariable adjustments. CONCLUSIONS:Postpartum higher-dose oxytocin administered over 1 hour compared with 8 hours was not associated with an increased treatment of PPH or frequency of hematocrit decline ≥ 6%.
journal_name
Am J Perinatoljournal_title
American journal of perinatologyauthors
Subramaniam A,Abramovici AR,Szychowski JM,Roach M,Owen J,Biggio JR,Tita ATdoi
10.1055/s-0034-1370347subject
Has Abstractpub_date
2014-11-01 00:00:00pages
1003-8issue
11eissn
0735-1631issn
1098-8785journal_volume
31pub_type
杂志文章abstract：:We evaluated the methodological quality of economic evaluation studies in the field of obstetrics and gynecology published in the last decade. A MEDLINE search was performed to find economic evaluation studies in obstetrics and gynecology from the years 1997 through 2009. We included full economic evaluation studies c...
journal_title：American journal of perinatology
pub_type： 杂志文章,评审
doi：10.1055/s-0032-1323591
更新日期：2013-04-01 00:00:00
abstract：:Chorioamnionitis has generally been thought to be a contraindication to attempting a delayed interval delivery in a multiple gestation. We present a twin gestation in which a delay of 88 days between the birth of the two infants occurred. Chorioamnionitis observed immediately after the delivery of Twin A was successfu...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-993962
更新日期：1998-06-01 00:00:00
abstract：:A hospital-based case-controlled study was undertaken to determine maternal and neonatal characteristics associated with fractured clavicle. A total of 11,604 consecutive vaginal deliveries of liveborn infants in vertex presentation at the Mount Sinai Hospital from 1988 to 1990 were reviewed. Maternal and neonatal cha...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-994546
更新日期：1994-09-01 00:00:00
abstract：:The present study of 466 consecutive liveborn preterm singleton deliveries included 238 cases of spontaneous preterm labor and delivery, 175 cases with premature rupture of membranes, 13 cases of nonhypertensive abruption, 18 cases of preeclampsia, and 22 cases of placenta previa. Placental infarction, chronic villiti...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-999318
更新日期：1992-05-01 00:00:00
abstract：OBJECTIVE:To determine if patients with a history of low pregnancy-associated plasma protein A (PAPP-A) in an initial pregnancy are at higher risk for adverse obstetric outcomes in a subsequent pregnancy. STUDY DESIGN:This was a retrospective cohort study in patients who underwent first trimester screening for PAPP-A ...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0038-1673651
更新日期：2019-05-01 00:00:00
abstract：OBJECTIVE:This article compares hemodynamic characteristics of neonates with hypoxic ischemic encephalopathy (HIE) receiving therapeutic hypothermia (TH) with normal versus abnormal brain magnetic resonance imaging (MRI). METHODS:Serial echocardiography (echo) was performed within 24 hours, after 48 to 72 hours of coo...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0038-1629900
更新日期：2018-08-01 00:00:00
abstract：OBJECTIVE:To evaluate if fundal (F) dominance of the electrohysterogram is associated with vaginal delivery and lack of F dominance is associated with cesarean for labor dystocia. STUDY DESIGN:We conducted a prospective cohort study of nulliparous women in spontaneous labor at ≥36 weeks. Clinicians were blinded to ele...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0038-1675621
更新日期：2019-07-01 00:00:00
abstract：OBJECTIVE:Delivery room (DR) management may play an important role in the development and prevention of lung injury. Therefore, in a cohort of low birth weight infants (LBW), we investigated the effects of two different lung recruitment maneuvers, such as positive pressure ventilation (PPV) and sustained inflation (SI)...
journal_title：American journal of perinatology
pub_type： 杂志文章,随机对照试验
doi：10.1055/s-0039-1692133
更新日期：2019-07-01 00:00:00
abstract：:Hermansky-Pudlak syndrome (HPS) is a multisystem, autosomal-recessive disorder characterized by oculocutaneous albinism, platelet storage pool deficiency resulting in prolonged bleeding, and ceroid lipofuscin deposition. Affected individuals may suffer from blindness, pulmonary fibrosis, colitis, and bleeding diathesi...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0029-1220777
更新日期：2009-10-01 00:00:00
abstract：OBJECTIVE:Systemic lupus erythematosus (SLE) increases the risk of complications in pregnancy. Hydroxychloroquine (HCQ) decreases flares and neonatal lupus syndrome. Limited evidence suggests that HCQ also reduces preeclampsia and preterm birth in SLE pregnancies. We studied whether HCQ was associated with lower odds o...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0039-3402752
更新日期：2020-07-01 00:00:00
abstract：:Pulmonary hypoplasia is lethal in its most severe form; in less severe cases the clinical course is protracted, usually resulting in chronic lung disease. A case of unexpected survival of an infant with clinical and radiologic evidence of pulmonary hypoplasia, in whom dexamethasone was administered, is presented. Poss...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-999375
更新日期：1991-05-01 00:00:00
abstract：:The objective of this study was to define the variables associated with vaginal birth after cesarean section (VBAC) and to develop a scoring system for the prediction of successful VBAC. We searched our computerized database for parturients with a history of one low-transverse cesarean section (CS) who were delivered ...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2004-835961
更新日期：2004-11-01 00:00:00
abstract：:We sought to identify maternal or clinical characteristics of women likely to develop preterm labor (PTL) at <34 weeks' gestation while receiving 17 alpha-hydroxyprogesterone caproate (17P) prophylaxis. Current singleton gestations with prior preterm delivery enrolled for outpatient 17P administration at <27 weeks' ge...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0029-1243306
更新日期：2010-04-01 00:00:00
abstract：:Although cesarean section is one of the most ancient surgical procedures, the origin of its name remains obscure. The term, however, did not originate because of the birth of the Roman Emperor Julius Caesar through this route. In fact, historians are certain that Julius Caesar was not delivered by the dangerous cesare...
journal_title：American journal of perinatology
pub_type： 历史文章,杂志文章
doi：10.1055/s-2007-986693
更新日期：2007-11-01 00:00:00
abstract：OBJECTIVE:To determine if increasing predicted risk of cesarean was associated with longer labor length and increased morbidity among women undergoing induction with an unfavorable cervix. STUDY DESIGN:Using a publically available database, we evaluated whether a previously validated prediction model for cesarean deli...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0038-1675625
更新日期：2019-05-01 00:00:00
abstract：:In 18 women with gestational diabetes the variables of an oral glucose tolerance test (fasting and 2-hour blood glucose values and area under the blood glucose curve) performed in the last trimester of pregnancy correlated significantly with the urinary C-peptide excretion during the first 12 hours of the life (r = 0....
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-999674
更新日期：1988-04-01 00:00:00
abstract：OBJECTIVE:To determine the accuracy of clinically estimated fetal weight (CEFW) in patients with gestational diabetes (GDM), pregestational diabetes (DM), and obesity. STUDY DESIGN:This is a retrospective analysis of Consortium of Safe Labor data. Subjects were classified into six groups: DM, DM and obese, GDM, GDM an...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0033-1334450
更新日期：2014-01-01 00:00:00
abstract：OBJECTIVE:To evaluate the interobserver reliability of fetal heart rate (FHR) pattern definition and interpretation assessed by physicians at various levels of training using standard Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) definitions and standard principles of interpret...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0032-1326991
更新日期：2013-06-01 00:00:00
abstract：AIM:The main purpose of this article is to assess trends in cytomegalovirus (CMV) infection reported among infants in California neonatal intensive care units (NICUs) during 2005 to 2016. STUDY DESIGN:The California Perinatal Quality Care Collaborative collects data on all very low birth weight (VLBW, birth weight ≤ 1...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0039-1683958
更新日期：2020-01-01 00:00:00
abstract：:Discordancy in twins is generally described as a weight difference between the fetuses of 15 to 25% and its prevalence in normal twin gestations is estimated at 15 to 29%. The present study was performed in order to determine the frequency of discordant newborns in uncomplicated triplet gestations. One hundred and fou...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-994724
更新日期：1993-05-01 00:00:00
abstract：:A prospective study of 377 premature infants (less than or equal to 1500 gm) was undertaken to delineate the natural history of subependymal/intraventricular hemorrhage (S/IVH) and its complications using ultrasound (US) and computed tomography (CT). Low grade (I, II) S/IVH had a low mortality while higher grades (III...
journal_title：American journal of perinatology
pub_type： 杂志文章,评审
doi：10.1055/s-2007-999929
更新日期：1985-04-01 00:00:00
abstract：:The findings of hyperechoic and enlarged fetal kidneys on routine antenatal ultrasonography is a non-specific finding that alerts the physician to a differential diagnosis of various genetic and non-genetic disorders, including fetal polycystic disease and Beckwith-Wiedeman syndrome. Detection of fetal or neonatal pol...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-994309
更新日期：1996-04-01 00:00:00
abstract：:Obstetrical antiphospholipid syndrome (APS) is associated with maternal and fetal morbidity and mortality. Standard treatment with low-dose acetylsalicylic acid and unfractionated heparin has achieved up to a 70 to 80% likelihood of success. Conversely, up to 30% of women with APS will have further pregnancy losses, d...
journal_title：American journal of perinatology
pub_type： 杂志文章,评审
doi：10.1055/s-2006-931805
更新日期：2006-02-01 00:00:00
abstract：OBJECTIVE: This work aimed to study perinatal, maternal, and neonatal characteristics of birth tourism (BT) mother-baby dyads and the rate of neonatal intensive care unit (NICU) admissions of BT infants. STUDY DESIGN: Retrospective study at a regional perinatal center comparing BT mother-baby dyads to all dyads. BT in...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0040-1719117
更新日期：2020-11-09 00:00:00
abstract：:The pregnant woman with idiopathic thrombocytopenic purpura (ITP) and her fetus-neonate present a number of challenging issues for both the perinatologist and neonatologist. A review of these issues within a single format is helpful because of the widely scattered nature of the pertinent information in the medical lit...
journal_title：American journal of perinatology
pub_type： 杂志文章,评审
doi：10.1055/s-2007-1000014
更新日期：1984-04-01 00:00:00
abstract：:Preeclampsia is uncommon prior to 24 weeks gestation and has been associated with partial and complete hydatidiform moles. We present an unusual case in which a patient was diagnosed with preeclampsia at 17 weeks gestation. Ultrasound findings were consistent with a partial hydatidiform mole. Within 24 hours of the on...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2006-934093
更新日期：2006-04-01 00:00:00
abstract：OBJECTIVE:To determine epidemiology and clinical characteristics of infants with methicillin-susceptible (MSSA) and -resistant Staphylococcus aureus (MRSA) in a level III neonatal intensive care unit (NICU). STUDY DESIGN:All NICU admissions (2001 to 2008) with any positive S. aureus culture were included as cases. Cas...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0032-1304819
更新日期：2012-06-01 00:00:00
abstract：:I developed a single equation that simulated previously published growth charts for very low-birth-weight infants, using birth weight as the only variable. The intent of this study was to validate the equation using infants admitted to our neonatal intensive care unit (NICU) and to determine if this equation could be ...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-993914
更新日期：1998-02-01 00:00:00
abstract：:Progress in neonatal care has decrease morbidity and mortality due to neonatal sepsis (NS). Although diagnosis of sepsis continues to rely on blood culture, this method is too slow and limited by false-negative results. There are numerous sepsis biomarkers that have been evaluated for the early diagnosis of NS, but, t...
journal_title：American journal of perinatology
pub_type： 杂志文章,评审
doi：10.1055/s-0038-1639361
更新日期：2018-05-01 00:00:00
abstract：OBJECTIVE:The objective of this article is to evaluate the implementation and acceptability of a universal cervical length (CL) screening program for prediction and prevention of preterm birth (PTB). STUDY DESIGN:We performed a prospective observational study to evaluate the implementation and acceptability of a unive...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0034-1371710
更新日期：2014-12-01 00:00:00
