Urinary C-peptide in the neonate correlates both to maternal glucose tolerance and to fetal size at birth.

Abstract:

:In 18 women with gestational diabetes the variables of an oral glucose tolerance test (fasting and 2-hour blood glucose values and area under the blood glucose curve) performed in the last trimester of pregnancy correlated significantly with the urinary C-peptide excretion during the first 12 hours of the life (r = 0.47, 0.71, and 0.60, respectively). In a combined group with 28 type II pregnant diabetic women there was also a significant correlation between the urinary C-peptide excretion of the infants and their skinfold. Assay of the urinary C-peptide excretion of the neonate, reflecting its insulin production, seems to be a sensitive parameter to study the influence of the maternal carbohydrate metabolism in the offspring.

journal_name

Am J Perinatol

authors

Lunell NO,Persson B,Devarajan LV,Hassan S,Hathout H,Kasrawi R,Saleh A,Viktorin L

doi

10.1055/s-2007-999674

subject

Has Abstract

pub_date

1988-04-01 00:00:00

pages

144-5

issue

2

eissn

0735-1631

issn

1098-8785

journal_volume

5

pub_type

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