Abstract:
:The objective of this article is to test whether the concentration of potentially oxidizable lipids (polyunsaturated fatty acids [PUFA], total and free cholesterol) and lipophilic antioxidants (plasmalogens, vitamin E) in the fetal lung correlate with lung maturation (P/S ratio). In amniotic fluid palmitic/stearic acid (P/S) ratio, concentrations of PUFA, total and free cholesterol, vitamin E, and plasmalogens were measured. Ratio of PUFA to stearic acid (PUFA/S ratio) was determined in lung effluent of 15 preterm infants with IRDS and compared with values from 15 term healthy infants. Concentrations of plasmalogens, PUFA, total and free cholesterol increase significantly with increasing P/S ratio. No correlation of vitamin E with lung maturation has been found. The PUFA/S ratio is significantly lower in lung effluent of preterm (0.79 +/- 0.27) when compared with term infants (2.02 +/- 0.38). Our results suggest that the higher susceptibility of preterm infants for oxidative lung injury is not caused by an unfavorable ratio of oxidizable lipids to lipophilic antioxidants in surfactant, but rather by a lower amount of PUFA containing surfactant lipids. Our results are in accordance with data from Sosenko et al. who have shown that high levels of PUFA in the rat lung have a protective effect against oxygen-induced lung damage.
journal_name
Am J Perinatoljournal_title
American journal of perinatologyauthors
Rüdiger M,Haupt R,Wauer RR,Rüstow Bdoi
10.1055/s-2007-993952subject
Has Abstractpub_date
1998-05-01 00:00:00pages
329-33issue
5eissn
0735-1631issn
1098-8785journal_volume
15pub_type
杂志文章abstract:OBJECTIVE: This study aimed to identify differences in sequential integrated screening and early ultrasound markers in monochorionic/diamniotic (MC/DA) pregnancies complicated by twin-to-twin transfusion syndrome (TTTS) and unequal placental sharing (UPS). STUDY DESIGN: Retrospective cohort study of MC/DA pregnancies ...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0040-1718371
更新日期:2020-10-08 00:00:00
abstract::A recent report has noted an association between Helicobacter pylori and hyperemesis gravidarum. We present two cases in which first-trimester patients with severe hyperemesis gravidarum requiring intravenous fluid replacement were placed on oral erythromycin therapy for other nonrelated conditions. Surprisingly, mark...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-994055
更新日期:1998-01-01 00:00:00
abstract::In this paper the results gathered in a longitudinal ultrasound study (LS) of fetal growth are presented. The study is unusual in design because of its homogeneity, the number of parameters recorded, the exact spacing between the examinations, and the number of examinations per subject. Information not available in th...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-999987
更新日期:1984-01-01 00:00:00
abstract::Cardiovascular disease (CVD) is the leading cause of death and disability among women, with more than half occurring in individuals with hypertension. New blood pressure criteria for the diagnosis of hypertension from the American College of Cardiology/American Heart Association recognize that there is no specific blo...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0038-1669441
更新日期:2019-03-01 00:00:00
abstract:OBJECTIVE: The purpose of this study was to compare the nulliparous-term-singleton-vertex (NTSV) and the Society of Maternal-Fetal Medicine (SMFM) cesarean birth metrics as tools for quality improvement efforts based on hospital size. MATERIALS AND METHODS: Cesarean birth rates from 275 hospitals from six states were ...
journal_title:American journal of perinatology
pub_type: 杂志文章,多中心研究
doi:10.1055/s-0037-1607985
更新日期:2018-03-01 00:00:00
abstract::The aim of the study was to investigate the effect of individual room care in the neonatal intensive care unit (NICU) on the factors that influence mother-preterm infant interaction. Mothers in group I had hospitalization with their preterm infants in an individual room in the NICU. Mothers in group II were not hospit...
journal_title:American journal of perinatology
pub_type: 杂志文章,多中心研究
doi:10.1055/s-0028-1095186
更新日期:2009-02-01 00:00:00
abstract:OBJECTIVE:The aim of the article is to review the effectiveness of neonatal noninvasive high-frequency ventilation (NIHFV) in preventing endotracheal mechanical ventilation. STUDY DESIGN:Retrospective case series including all 79 instances of NIHFV use at four participating centers between July 2010 and September 2012...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0034-1381317
更新日期:2015-02-01 00:00:00
abstract::As new information about coronavirus disease 2019 (COVID-19) is rapidly discovered, clinicians are better equipped to make informed decisions for their patients. While current research suggests COVID-19 viral antigen is not found in vaginal secretions, its detectability in the female lower genital tract may have clini...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0040-1713665
更新日期:2020-09-01 00:00:00
abstract::Ehlers-Danlos syndrome type IV (EDS IV) is a rare but serious disorder of connective tissue that is characterized by the abnormal production or secretion of type III collagen. Experience with pregnant patients exhibiting this syndrome is limited. This report describes the successful management of a pregnancy in a woma...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-999756
更新日期:1987-04-01 00:00:00
abstract::The purpose of this study was to establish normative reference values for serum unconjugated estriol (E3) concentrations in insulin-dependent diabetic pregnancy. There were 1973 samples analyzed in 63 diabetic pregnancies not complicated by fetal distress and/or neonatal asphyxia. These samples were compared with 867 ...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-999718
更新日期:1988-10-01 00:00:00
abstract::It has been suggested that vibroacoustic stimulation might be stressful to the fetus. The present study was designed to evaluate whether the stimulus induces passage of meconium in labor. Patients in labor at term with healthy fetuses and intact membranes were randomized to a vibroacoustic stimulation or sham test. Th...
journal_title:American journal of perinatology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1055/s-2007-994297
更新日期:1996-02-01 00:00:00
abstract::This report describes 40 consecutive emergency cerclages on dilated and effaced cervices prior to 26 weeks' gestation. These "emergency" cerclages were associated with a mean extension of gestational age of 12 weeks (range, 3 days to 20.5 weeks). Thirty-one of 40 pregnancies were carried to 28 weeks' gestation and 23 ...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-999307
更新日期:1992-05-01 00:00:00
abstract::The accuracy of eight ultrasonic fetal weight formulas were analyzed in 1099 fetuses who underwent real-time ultrasound examination within 72 hours prior to delivery. Shepard's formula was most consistently found to give the lowest systematic and random errors throughout all weight categories, though Deter's formula h...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-999944
更新日期:1985-07-01 00:00:00
abstract:OBJECTIVE:The aim of the study is to conduct an initial pilot trial evaluating the feasibility, safety, and efficacy of bupropion for smoking cessation in pregnancy. STUDY DESIGN:A randomized, double-blind, parallel-group pilot study of bupropion versus placebo with 50 pregnant smokers was planned. Eligibility criteri...
journal_title:American journal of perinatology
pub_type: 杂志文章,随机对照试验
doi:10.1055/s-0034-1386635
更新日期:2015-03-01 00:00:00
abstract::Objective The aim of this article is to examine characteristics of birth tourism (BT) neonates admitted to a neonatal intensive care unit (NICU). Methods This was a retrospective review over 3 years; BT cases were identified, and relevant perinatal, medical, social, and financial data were collected and compared with ...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0036-1584139
更新日期:2016-12-01 00:00:00
abstract::The objective of this study was to identify the most efficient and cost-effective nebulizer device for delivery of albuterol aerosol as a bronchodilator in ventilated preterm infants. Bronchodilators are frequently used as part of the therapeutic regimen of ventilated preterm infants. This can be delivered by differen...
journal_title:American journal of perinatology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1055/s-2001-14526
更新日期:2001-05-01 00:00:00
abstract::We sought (1) to identify risk factors for meconium aspiration syndrome (MAS) among infants born to women whose labors were complicated by thick-consistency meconium-stained amniotic fluid (MSAF), and (2) to determine whether risk factors and infant prognosis differ according to the time of onset of respiratory distre...
journal_title:American journal of perinatology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1055/s-0029-1241740
更新日期:2010-04-01 00:00:00
abstract:OBJECTIVE: The aim was to determine the fetal umbilical blood gas effects of supplemental maternal oxygenation compared with room air (RA) during term planned cesarean delivery. METHODS: This is a prospective randomized controlled study of singleton planned cesarean deliveries randomized to receive supplemental oxygen...
journal_title:American journal of perinatology
pub_type: 杂志文章,随机对照试验
doi:10.1055/s-0037-1606184
更新日期:2018-01-01 00:00:00
abstract::The ultrastructural architecture of colostral cells of mothers of pre- and full-term infants is described. The polymorphonuclears were engaged in vivid phagocytosis of fat droplets. Similar findings were observed on the macrophages. The lymphocytes appeared normal in size and ultrastructure. A small number of eosinoph...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-994162
更新日期:1997-07-01 00:00:00
abstract:OBJECTIVE:Normal initial blood glucose values in healthy newborns are not well defined and are subject to controversy. Despite substantive research, there is no single initial value of glucose that can be used with certainty of safety in newborns, and thus various protocols and cutoffs have been proposed. STUDY DESIGN...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0038-1667293
更新日期:2019-01-01 00:00:00
abstract::We sought to report an updated incidence, risk factors, and outcome of traumatic facial palsy (TFP) in newborn infants born at King Abdulaziz Medical City (KAMC), Riyadh, Saudi Arabia. We performed a 12-year retrospective study at KAMC. The records of infants with the diagnosis of TFP during the study period were revi...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0030-1253097
更新日期:2010-10-01 00:00:00
abstract:OBJECTIVE: Severe maternal morbidity (SMM) has increased by 45% in the United States and is estimated to affect up to 1.5% of all deliveries. Research has not yet been conducted that demonstrates a benefit to multidisciplinary review of SMM. The aim of our study was to determine if standardized, routine review of the c...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0040-1715846
更新日期:2020-08-30 00:00:00
abstract::The aim of this study was to determine the relationship between maternal serum homocysteine levels in preeclampsia and the severity of the disease, neonatal serum homocysteine levels, maternal complications, and fetal outcome. Fifty pregnant women were included in this prospective study, of which 25 were severe (group...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2005-918889
更新日期:2006-01-01 00:00:00
abstract:OBJECTIVE:Surfactant and noninvasive ventilation are two major strategies for the treatment of neonates with respiratory distress syndrome (RDS). However, the optimal time for surfactant administering is yet controversial. This study compared the early and rescue Calsurf administration in preterm infants with RDS. STU...
journal_title:American journal of perinatology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1055/s-0039-1678530
更新日期:2019-12-01 00:00:00
abstract::The aim of this study was to determine the risk of respiratory distress syndrome (RDS) and neonatal death (NND) in relation to birth weight in preterm neonates. A group of 255 singleton preterm neonates born at 22-36 weeks were examined. The mean birth weight for each gestational week was estimated from a fitted curve...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-994327
更新日期:1997-10-01 00:00:00
abstract::This is the first reported case in which a Logothetopulos pack was utilized to achieve pelvic hemostasis in a patient requiring a cesarean hysterectomy for placenta accreta with postpartum hemorrhage. The Logothetopulos pack is an easily constructed gauze tamponade method that proved to be life-saving in this case. ...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-999514
更新日期:1990-10-01 00:00:00
abstract::Four hundred sixty-four fetuses underwent real time ultrasound examination within 72 hours before birth to evaluate other factors than the weight formula itself that might influence the accuracy of ultrasound weight estimation. The results indicated that fetal sex had no effect on weight estimation accuracy, but that ...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-999866
更新日期:1986-07-01 00:00:00
abstract::Gestational diabetes mellitus (GDM) has increased dramatically in the past 20 years together with the obesity epidemic. Mirroring the increase in incidence of GDM is increasing use of endocrine disrupting chemicals (EDCs). EDCs are structurally similar to endogenous hormones and interfere with synthesis, secretion, ac...
journal_title:American journal of perinatology
pub_type: 杂志文章,评审
doi:10.1055/s-0036-1586500
更新日期:2016-11-01 00:00:00
abstract:OBJECTIVE:To assess the association between altitudes of neonatal intensive care units (NICU) and the rate of bronchopulmonary dysplasia (BPD) and BPD/death in very preterm infants. STUDY DESIGN:Data from infants born at <33 weeks' gestation admitted to Canadian Neonatal Network during 2008 and 2009 were analyzed. The...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0032-1329690
更新日期:2013-08-01 00:00:00
abstract::Interest in centralized monitoring in labor and delivery units is growing because it affords the opportunity to monitor multiple patients simultaneously. However, a long history of research on sustained attention reveals these types of monitoring tasks can be problematic. The goal of the present experiment was to exam...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0030-1268718
更新日期:2011-06-01 00:00:00