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Opioid Use Disorder during Antepartum and Postpartum Hospitalizations.

Abstract：

OBJECTIVE:This study aimed to evaluate temporal trends in opioid use disorder (OUD) during antepartum and postpartum hospitalizations. STUDY DESIGN:This repeated cross-sectional analysis analyzed data from the National (Nationwide) Inpatient Sample. Women aged 15 to 54 years admitted antepartum or postpartum were identified. The presence of OUD was determined based on a diagnosis of opioid abuse, opioid dependence, or opioid overdose. Temporal trends in OUD were evaluated using the Rao-Scott chi-square test. Temporal trends in opioid overdose were additionally evaluated. RESULTS:An estimated 7,336,562 antepartum hospitalizations and 1,063,845 postpartum readmissions were included in this analysis. The presence of an OUD diagnosis during antepartum hospitalizations increased from 0.7% of patients in 1998 to 1999 to 2.9% in 2014 (p < 0.01) and during postpartum hospitalizations increased from 0.8% of patients in 1998 to 1999 to 2.1% of patients in 2014 (p < 0.01). Risk of overdose diagnoses increased significantly for both antepartum hospitalizations, from 22.7 per 100,000 hospitalizations in 1998 to 2000 to 70.3 per 100,000 hospitalizations in 2013 to 2014 (p < 0.001), and postpartum hospitalizations, from 18.8 per 100,000 hospitalizations in 1998 to 2000 to 65.2 per 100,000 hospitalizations in 2013 to 2014 (p = 0.02). DISCUSSION:Risk of OUD diagnoses and overdoses increased over the study period for both antepartum and postpartum hospitalizations.

journal_name

Am J Perinatol

journal_title

American journal of perinatology

authors

Kern-Goldberger AR,Huang Y,Polin M,Siddiq Z,Wright JD,D'Alton ME,Friedman AM

doi

10.1055/s-0039-1694725

subject

Has Abstract

pub_date

2020-12-01 00:00:00

pages

1467-1475

issue

14

eissn

0735-1631

issn

1098-8785

journal_volume

37

pub_type

杂志文章

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