Serum erythropoietin quantitation in pregnancy using an enzyme-linked immunoassay.

Abstract:

:During normal pregnancy there is a decrease in the hematocrit due to a disproportionate increase in the blood volume compared with the red cell mass. Using a new enzyme-linked immunoassay (Amgen Diagnostics), serum erythropoietin was quantified in normal nonanemic pregnancies throughout gestation and in third trimester anemic patients. We found that the mean hematocrit in normal pregnancy reached a nadir late in the second trimester and the serum erythropoietin plateaued at a 50% increase. Those pregnancies complicated by anemia defined by a hematocrit less than 30 vol% demonstrated a statistically significant increase in serum erythropoietin above those not anemic.

journal_name

Am J Perinatol

authors

Harstad TW,Mason RA,Cox SM

doi

10.1055/s-2007-994778

subject

Has Abstract

pub_date

1992-07-01 00:00:00

pages

233-5

issue

4

eissn

0735-1631

issn

1098-8785

journal_volume

9

pub_type

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