Impact of oral versus intravenous ibuprofen on neurodevelopmental outcome: a randomized controlled parallel study.

Abstract:

OBJECTIVE:Although neurodevelopmental outcomes related to the management of patent ductus arteriosus with intravenous indomethacin and ibuprofen are known, little data on the long-term effects of oral ibuprofen can be found in the literature. METHOD:A follow-up study of 99 infants with birth weight ≤ 1,500 g and gestational age ≤ 32 weeks who received either oral or intravenous ibuprofen for patent ductus arteriosus was conducted to assess at 18 to 24 months (corrected age), abnormal neurological, neurosensory, and cognitive impairment were defined as follows:neurological outcomes included moderate/severe cerebral palsy, neurosensory outcomes included bilateral hearing loss and blindness in either eye, and cognitive impairment included mental developmental index score < 70. RESULTS:The 18- to 24-month (corrected age) long-term outcomes of 30 subjects who received oral ibuprofen were compared with 27 subjects who received intravenous ibuprofen by certified and experienced examiners who were blind to the definitions of the groups. The results revealed that the long-term outcomes of the treatment regimens did not significantly differ. CONCLUSIONS:Preterm infants who were treated with oral ibuprofen for patent ductus arteriosus had similar neurological, neurosensory, and cognitive outcomes to patients who received intravenous ibuprofen at 2 years of age.

journal_name

Am J Perinatol

authors

Eras Z,Gokmen T,Erdeve O,Ozyurt BM,Saridas B,Dilmen U

doi

10.1055/s-0033-1333667

subject

Has Abstract

pub_date

2013-11-01 00:00:00

pages

857-62

issue

10

eissn

0735-1631

issn

1098-8785

journal_volume

30

pub_type

杂志文章,随机对照试验
  • Recombinant human Clara cell secretory protein treatment increases lung mRNA expression of surfactant proteins and vascular endothelial growth factor in a premature lamb model of respiratory distress syndrome.

    abstract::Infant respiratory distress syndrome (IRDS) can lead to impaired alveolarization and dysmorphic vascularization of bronchopulmonary dysplasia. Clara cell secretory protein (CC10) has anti-inflammatory properties but is deficient in the premature infant. Because surfactant and vascular endothelial growth factor (VEGF) ...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-0028-1090587

    authors: Wolfson MR,Funanage VL,Kirwin SM,Pilon AL,Shashikant BN,Miller TL,Shaffer TH

    更新日期:2008-11-01 00:00:00

  • Meconium plugs and intussusception in a premature infant.

    abstract::Neonatal intussusception in premature infants is uncommon and may mimic other abdominal disorders. We present a case of intussusception in a very low birthweight neonate. Presenting signs initially suggested necrotizing enterocolitis and meconium disease, and the diagnosis was confirmed at laparotomy. ...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-2007-999916

    authors: Glick B,Alpan G,Vinograd I,Udassin R,Mogle P,Eyal F

    更新日期:1985-04-01 00:00:00

  • Evaluation of a universal real-time polymerase chain reaction for detection of amniotic fluid infection in premature rupture of membranes.

    abstract::Managing preterm rupture of membranes (PPROM) is a balance between benefits of prolonging gestation and the risks of perinatal infection. This study evaluates a real-time polymerase chain reaction (PCR) for the detection of amniotic fluid infection and neonatal complications by amniocentesis following PPROM. A total o...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-0030-1271212

    authors: Debiève F,Ska S,Williams O,Hutchings G,Bernard P,Grandjean P,Hubinont C

    更新日期:2011-08-01 00:00:00

  • Use of quantitative amniotic fluid phosphatidylglycerol as a criterion for fetal lung maturation.

    abstract::Phosphatidylglycerol (PG) in amniotic fluid was quantitatively measured by thin-layer chromatography (TLC) in 941 amniotic fluid samples and related to the presence or absence of respiratory distress syndrome (RDS) in neonates born within 7 days of the amniocentesis. In 639 case tests with PG 1 nmol/ml or more of amni...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-2007-994666

    authors: Tsao FH,Zachman RD

    更新日期:1992-01-01 00:00:00

  • Application of transcutaneous carbon dioxide tension monitoring with low electrode temperatures in premature infants in the early postnatal period.

    abstract:OBJECTIVE:The aim of this article is to evaluate the accuracy, precision, and safety of transcutaneous carbon dioxide tension (TcPCO2) monitoring at different electrode temperatures in preterm infants in the early postnatal period. STUDY DESIGN:A total of 26 neonates with a median birth weight of 974 g (432-1,694 g) a...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-0033-1352485

    authors: Hirata K,Nishihara M,Oshima Y,Hirano S,Kitajima H

    更新日期:2014-05-01 00:00:00

  • Clinical Tolerance of In-Neonatal Intensive Care Unit Administration of Rotavirus Vaccine.

    abstract:OBJECTIVE: This article determines the tolerance of neonatal intensive care unit (NICU)-based administration of RV5 in premature infants. This article also aims to compare the rate of clinically significant adverse events after RV5 immunization to the standard 2-month shot series and to historical controls who were not...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-0039-1698455

    authors: Briggs-Steinberg C,Aboudi D,Hodson G,Shah S

    更新日期:2019-11-18 00:00:00

  • Do fiber-enriched diabetic diets have glucose-lowering effects in pregnancy?

    abstract::A fiber-enriched diabetic diet that contained a modest increase in dietary fiber and a commercially available fiber supplement was studied in pregnant diabetic women for its potential glucose-lowering effects. Noninsulin-requiring gestational diabetic patients were placed on a fiber-enriched diet of increasing fiber c...

    journal_title:American journal of perinatology

    pub_type: 临床试验,杂志文章

    doi:10.1055/s-2007-994738

    authors: Reece EA,Hagay Z,Caseria D,Gay LJ,DeGennaro N

    更新日期:1993-07-01 00:00:00

  • Ultrasonically measured biparietal diameter and abdominal circumference: intra- and interobserver variation in the third trimester.

    abstract::Serial ultrasound measurements of the fetus under investigation is an important indicator of fetal growth, and thus fetal health. To assess how reliable those measurements are, a videotape was made, and, utilizing an ultrasound machine that allowed the placement of callipers on the videotape, the dispersion of the mea...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-2007-999271

    authors: Vine DG,Cooperberg PL,Dansereau J

    更新日期:1992-09-01 00:00:00

  • Long-Term Outcomes of Small for Gestational Age Twins Born at 34 Weeks or Later.

    abstract:OBJECTIVE: This article aims to compare long-term neurodevelopmental and health outcomes of twins born at 34 weeks or later, based on the presence of small for gestational age (SGA). STUDY DESIGN: This study is a mail-based survey of twin gestations delivered by a single practice. We compared twins with and without SG...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-0037-1607043

    authors: Herlihy N,Odom E,Cohen N,Stroustrup A,Rebarber A,Fox NS

    更新日期:2018-02-01 00:00:00

  • The use of clinical, biochemical, and ultrasound parameters for the diagnosis of intrauterine growth retardation.

    abstract::Fifty-four pregnant patients referred for nonstress testing with findings suggestive of intrauterine growth retardation (IUGR) were followed with serial biochemical determinations and ultrasound evaluations. Confirmation of IUGR was made in 18 of the neonates based on body weights below the 10th percentile. Stepwise d...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-2007-999770

    authors: Hassan MM,Bottoms SF,Mariona FG,Syner FN,Simkowski KM,Sokol RJ

    更新日期:1987-07-01 00:00:00

  • Outpatient oral misoprostol for prolonged pregnancies: a pilot investigation.

    abstract:UNLABELLED:We evaluated the effectiveness of oral misoprostol for outpatient cervical ripening and labor induction in prolonged pregnancies. We performed a randomized, double-blind, placebo-controlled study of women at 40 to 42 weeks' gestation with well-dated pregnancies, singleton gestations, Bishop scores less than ...

    journal_title:American journal of perinatology

    pub_type: 杂志文章,随机对照试验

    doi:10.1055/s-0029-1220790

    authors: Gaffaney CA,Saul LL,Rumney PJ,Morrison EH,Thomas S,Nageotte MP,Wing DA

    更新日期:2009-10-01 00:00:00

  • Temporal Profile of Early Pulmonary Hypertension in Preterm Infants.

    abstract::Objective The objective of this study was to study the temporal profile of pulmonary hypertension (PH) in preterm infants. Study Design Infants < 28 weeks were screened for early PH at 10 to 14 days of life. Infants with early PH (n = 10) and gestationally matched controls (n = 18) underwent serial echocardiography ev...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-0036-1581079

    authors: Mirza H,Ziegler J,Ford S,Padbury J,Tucker R,Laptook A

    更新日期:2016-07-01 00:00:00

  • Survival and ventilatory course of a regional cohort of very low birthweight (501-1500 gm) infants.

    abstract::To minimize the selection bias inherent in reporting results gathered only in neonatal intensive care units, this study presents survival and respiratory course data on all 299 infants of birthweight 501 to 1500 gm liveborn to residents of the North Central Illinois Perinatal Region in 1985-1986. The survival rate was...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-2007-999632

    authors: Powers WF,Hegwood PD

    更新日期:1989-10-01 00:00:00

  • Severe Maternal Morbidity and Hospital Cost among Hospitalized Deliveries in the United States.

    abstract:OBJECTIVE:The objective of this study was to estimate the contemporary national rate of severe maternal morbidity (SMM) and its associated hospital cost during delivery hospitalization. STUDY DESIGN:We conducted a retrospective study identifying all delivery hospitalizations in the United States between 2011 and 2012....

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-0038-1649481

    authors: Chen HY,Chauhan SP,Blackwell SC

    更新日期:2018-11-01 00:00:00

  • Nasogastric versus Orogastric Bolus Tube Feeding in Preterm Infants: Pilot Randomized Clinical Trial.

    abstract:OBJECTIVE: According to the most recent metanalysis, the best way to establish safe enteral feeding in preterm babies using nasogastric or orogastric tubes is still not well understood. This study aimed to determine the effects of bolus nasal tubes versus bolus orogastric tubes on the time required to reach full entera...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-0040-1713865

    authors: Badran AT,Hashish M,Ali A,Shokeir M,Shabaan A

    更新日期:2020-07-03 00:00:00

  • Fetal myocardial calcification associated with maternal cocaine use.

    abstract::Two cases of fetal myocardial calcification confirmed postnatally are reported. In contrast to other reports, both infants survived with resolution of calcification by 6 and 12 months. Diagnostic investigations failed to confirm the presence of congenital infection. Both pregnancies were complicated by early cocaine u...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-2008-1040740

    authors: Yap TE,Diana D,Herson V,Chameides L,Rowe JC

    更新日期:1994-05-01 00:00:00

  • Impact of Azithromycin-Based Extended-Spectrum Antibiotic Prophylaxis on Noninfectious Cesarean Wound Complications.

    abstract:OBJECTIVE:Adding azithromycin to standard antibiotic prophylaxis for unscheduled cesarean delivery has been shown to reduce postcesarean infections. Because wound infection with ureaplasmas may not be overtly purulent, we assessed the hypothesis that azithromycin-based extended-spectrum antibiotic prophylaxis also redu...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-0039-1679914

    authors: Ausbeck EB,Jauk VC,Boggess KA,Saade GR,Longo S,Clark EAS,Esplin S,Cleary K,Wapner R,Letson K,Owens M,Abramovici A,Ambalavanan N,Szychowski JM,Andrews W,Tita ATN,Cesarean Section Optimal Antibiotic Prophylaxis Trial Consor

    更新日期:2019-07-01 00:00:00

  • Use of noninvasive high-frequency ventilation in the neonatal intensive care unit: a retrospective review.

    abstract:OBJECTIVE:The aim of the article is to review the effectiveness of neonatal noninvasive high-frequency ventilation (NIHFV) in preventing endotracheal mechanical ventilation. STUDY DESIGN:Retrospective case series including all 79 instances of NIHFV use at four participating centers between July 2010 and September 2012...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-0034-1381317

    authors: Mukerji A,Singh B,Helou SE,Fusch C,Dunn M,Belik J,Shah V

    更新日期:2015-02-01 00:00:00

  • Conflicts between physicians and patients in non-elective cesarean delivery: incidence and the adequacy of informed consent.

    abstract::A study was undertaken in 372 consecutive patients undergoing non-elective cesarean delivery to explore the incidence and nature of conflicts between physician and patient surrounding the decision to undergo non-elective cesarean delivery; to examine the adequacy of informed consent at the time of non-elective cesarea...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-2007-994319

    authors: Lescale KB,Inglis SR,Eddleman KA,Peeper EQ,Chervenak FA,McCullough LB

    更新日期:1996-04-01 00:00:00

  • Perinatal outcome in the live-born infant with prenatally diagnosed omphalocele.

    abstract::We compared perinatal outcomes between live-born nonisolated and isolated omphaloceles diagnosed during a prenatal ultrasound. Fetuses (n = 86) with omphalocele were identified between 1995 and 2007 at a single institution. Inclusion criteria were an omphalocele >14 weeks' gestation, available fetal and/or neonatal ka...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-0031-1276737

    authors: Kominiarek MA,Zork N,Pierce SM,Zollinger T

    更新日期:2011-09-01 00:00:00

  • Twin pregnancy after orthotopic liver transplantation, with exacerbation of chronic graft rejection.

    abstract::We report the sixth pregnancy and the first occurrence of twins after liver transplantation, and the second time cyclosporine was used in pregnancy for that indication. The pregnancy was interrupted at 33 weeks, menstrual age, for exacerbation of chronic graft rejection and intrauterine growth retardation of both twin...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-2007-999362

    authors: Grow DR,Simon NV,Liss J,Delp WT

    更新日期:1991-03-01 00:00:00

  • Resolving polyhydramnios. A sign of improved fetal status.

    abstract::Four cases of transient polyhydramnios are reviewed. It is proposed that by taking note of changes in amniotic fluid volume, one can more accurately assess a fetal-maternal unit that is affected by a number of specific disease processes. ...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-2007-999656

    authors: Hill LM

    更新日期:1988-01-01 00:00:00

  • Oxytocin receptor blockade: a new principle in the treatment of preterm labor?

    abstract::The concentration of myometrial and decidual oxytocin receptors increases dramatically in normal women in late pregnancy, causing enhanced uterine sensitivity to physiologic levels of oxytocin. Similar increase in myometrial oxytocin receptors has been found in women in preterm labor, indicating a role for oxytocin al...

    journal_title:American journal of perinatology

    pub_type: 临床试验,杂志文章

    doi:10.1055/s-2007-999575

    authors: Andersen LF,Lyndrup J,Akerlund M,Melin P

    更新日期:1989-04-01 00:00:00

  • Noninvasive measurement of cardiac output in healthy preterm and term newborn infants.

    abstract::Although values for cardiac output in the newborn infant have been reported previously, the methods utilized have been invasive. To assess if cardiac output could be determined noninvasively in the neonate, we measured mean ascending aortic blood flow velocity (VAo) in well newborns using a portable 5MHz, range gated,...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-2007-999991

    authors: Alverson DC,Eldridge MW,Johnson JD,Aldrich M,Angelus P,Berman W Jr

    更新日期:1984-01-01 00:00:00

  • A Comparison of the Nulliparous-Term-Singleton-Vertex and Society of Maternal-Fetal Medicine Cesarean Birth Metrics Based on Hospital Size.

    abstract:OBJECTIVE: The purpose of this study was to compare the nulliparous-term-singleton-vertex (NTSV) and the Society of Maternal-Fetal Medicine (SMFM) cesarean birth metrics as tools for quality improvement efforts based on hospital size. MATERIALS AND METHODS: Cesarean birth rates from 275 hospitals from six states were ...

    journal_title:American journal of perinatology

    pub_type: 杂志文章,多中心研究

    doi:10.1055/s-0037-1607985

    authors: Shields LE,Walker S,Hedriana HL,Wiesner S,Pelletreau B,Hitti J,Benedetti TJ

    更新日期:2018-03-01 00:00:00

  • Variation in the management of persistent pulmonary hypertension of the newborn: a survey of physicians in Canada, Australia, and New Zealand.

    abstract:BACKGROUND:Despite advances in management of persistent pulmonary hypertension of the newborn (PPHN), the risk of mortality and adverse neurological sequelae remains high. Characterizing variation in practices is a crucial step toward improved patient outcome. OBJECTIVE:Evaluate intensive care practices in Canada and ...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-0032-1310523

    authors: Shivananda S,Ahliwahlia L,Kluckow M,Luc J,Jankov R,McNamara P

    更新日期:2012-08-01 00:00:00

  • Are maternal serum troponin I levels affected by vaginal or cesarean delivery?

    abstract::Our objective was to describe the change in the level of troponin I in patients who undergo a vaginal or cesarean delivery. We obtained troponin I levels on admission and 1 hour after delivery in women undergoing vaginal and cesarean deliveries. Exclusion criteria included <37 weeks' gestation, a history of cardiac di...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-2004-820507

    authors: Koscica KL,Bebbington M,Bernstein PS

    更新日期:2004-01-01 00:00:00

  • Do postnatal glucocorticoids and retinopathy of prematurity relate?

    abstract::To study a possible relation between the use of postnatal glucocorticoids and the incidence and severity of retinopathy of prematurity (ROP), we conducted a retrospective study over a 4-year period that compared data of 161 preterm infants treated with hydrocortisone for bronchopulmonary dysplasia (BPD) with the data ...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-2000-13437

    authors: Termote J,Schalij-Delfos NE,Donders AR,Cats BP

    更新日期:2000-01-01 00:00:00

  • Neonatal effects of magnesium sulfate given to the mother.

    abstract:OBJECTIVE:Magnesium historically has been used for treatment and/or prevention of eclampsia or preterm labor. More recently, antepartum magnesium sulfate has been suggested for prevention of cerebral palsy in preterm infants. Although adverse effects and toxicity of magnesium in pregnant women are well known, the fetal...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-0032-1316440

    authors: Abbassi-Ghanavati M,Alexander JM,McIntire DD,Savani RC,Leveno KJ

    更新日期:2012-11-01 00:00:00

  • Percutaneous Inserted Venous Catheter via Femoral Vein in Extremely Low-Birth-Weight Infants: A Single-Center Experience.

    abstract:OBJECTIVE:This study aimed to assess the applicability of the insertion of small diameter catheters through the femoral vein in extremely low-birth-weight (ELBW) infants. STUDY DESIGN:All femoral small diameter catheters (Silastic or femoral arterial catheter [FAC]) inserted in ELBW infants in a tertiary level neonata...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-0039-1693718

    authors: Bergón-Sendín E,Soriano-Ramos M,Méndez-Marín MD,De Miguel-Moya M,Fontiveros-Escalona D,Diezma-Godino M,Pallás-Alonso CR,Moral-Pumarega MT

    更新日期:2020-12-01 00:00:00