Acute onset of severe hemolysis, elevated liver enzymes, and low platelet count syndrome in a patient with a partial hydatidiform mole at 17 weeks gestation.

Abstract:

:Preeclampsia is uncommon prior to 24 weeks gestation and has been associated with partial and complete hydatidiform moles. We present an unusual case in which a patient was diagnosed with preeclampsia at 17 weeks gestation. Ultrasound findings were consistent with a partial hydatidiform mole. Within 24 hours of the onset of symptoms, the patient developed severe hemolysis, elevated liver enzymes, and low platelet count syndrome, with a platelet count of 20 x 10 (9) cells/L. Termination of pregnancy was performed with rapid resolution of signs, symptoms, and laboratory abnormalities. Triploid 69,XXY was confirmed at karyotype analysis. This case demonstrates the acuteness in which life-threatening maternal conditions can arise with this uncommon complication of pregnancy, and the importance of correct identification of the characteristic ultrasonographic findings associated with a partial hydatidiform mole.

journal_name

Am J Perinatol

authors

Sherer DM,Dalloul M,Stimphil R,Hellmann M,Khoury-Collado F,Osho J,Fomitcheva L,Brennan KJ,Abulafia O

doi

10.1055/s-2006-934093

subject

Has Abstract

pub_date

2006-04-01 00:00:00

pages

163-6

issue

3

eissn

0735-1631

issn

1098-8785

journal_volume

23

pub_type

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