Abstract：
:We assessed the pattern of levo-thyroxine (l-thyroxine) therapy in very premature newborns over a 10-year period. We analyzed the electronic database of a large private neonatal practice group (Pediatrix, Ft. Lauderdale, FL) for 23- to 32-week gestation neonates ( N = 96,813) managed during 1997 to 2006. L-thyroxine use was analyzed by birth year and by gestational age (GA). L-thyroxine use increased with decreasing GA (nadir 0.3% at 32 weeks, peak 8.4% at 24 weeks). L-thyroxine supplementation increased 2.6-fold over time among infants ≤26 weeks' GA (3.4% in 1997 to 1999 to 8.7% in 2004 to 2006), but did not change among infants born at ≥29 weeks' GA. The highest rate of l-thyroxine supplementation (12.8%) occurred among 24-week GA infants in 2006. Median age at start of l-thyroxine was 23 days (25 to 75%, 15 to 38 days). Only 2% of treated infants were started on day of life 1. Despite no clear evidence from randomized trials supporting thyroid supplementation, l-thyroxine treatment of very preterm infants has significantly increased over the past decade. As l-thyroxine treatment was not consistent with protocols from published randomized trials, new focused randomized controlled trials are needed.
journal_name
Am J Perinatoljournal_title
American journal of perinatologyauthors
Linn M,Yoder BA,Clark RHdoi
10.1055/s-0030-1253556subject
Has Abstractpub_date
2010-10-01 00:00:00pages
731-5issue
9eissn
0735-1631issn
1098-8785journal_volume
27pub_type
杂志文章abstract：:The purpose of this study was to compare risk factors between placental abruption and placenta previa among primiparous and multiparous singleton pregnancies. We analyzed data from a population-based retrospective cohort with singleton pregnancies in the United States for 1995 to 2000. Maternal risk factors for placen...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0028-1103156
更新日期：2009-04-01 00:00:00
abstract：OBJECTIVE:To determine if preincubation with prostaglandin E1 (PGE1) and E2 (PGE2) enhances oxytocin-induced myometrial contractility in vitro. STUDY DESIGN:Myometrial strips from 13 women were incubated with PGE1 (10-5 mol/L or 10-6 mol/L), PGE2 (10-5 mol/L or 10-6 mol/L) or solvent before adding cumulative concentra...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0032-1329696
更新日期：2013-09-01 00:00:00
abstract：OBJECTIVE: This study aimed to assess risk for fetal acidemia, low Apgar scores, and hypoxic ischemic encephalopathy based on decision-to-incision time interval in the setting of emergency cesarean delivery. STUDY DESIGN: This unplanned secondary analysis of the Maternal-Fetal Medicine Units prospective observational ...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0040-1717068
更新日期：2020-09-21 00:00:00
abstract：OBJECTIVE: The aim of this study is to determine patterns of neurally adjusted ventilatory assist (NAVA) use in ventilator-dependent preterm infants with evolving or established severe bronchopulmonary dysplasia (sBPD) among centers of the BPD Collaborative, including indications for its initiation, discontinuation, an...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0040-1708559
更新日期：2020-03-24 00:00:00
abstract：:Arteriovenous malformations of the Vein of Galen continue to present diagnostic and therapeutic challenges in the neonatal period. Approximately 40-50% of all malformations of the Vein of Galen present in the neonatal period, usually with congestive heart failure. These neonates represent the most severe cases and are...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2000-13456
更新日期：2000-01-01 00:00:00
abstract：OBJECTIVE: Neuromuscular re-education (NMRE) therapy including bracing, containment, facilitation techniques, joint compression, weight (WT) bearing, and myofascial release has been shown to improve neurodevelopmental maturation in premature infants. This study aimed to examine the association of NMRE with growth param...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0040-1716492
更新日期：2020-09-11 00:00:00
abstract：OBJECTIVE: Potentially avoidable maternity complications (PAMCs) have been validated as an indicator of access to quality prenatal care. African-American mothers have exhibited a higher incidence of PAMCs, which has been attributed to unequal health coverage. The objective of this study was to assess if racial disparit...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0040-1701195
更新日期：2020-01-27 00:00:00
abstract：OBJECTIVE:The Misgav-Ladach technique is recommended worldwide to perform cesarean sections but there is no consensus about the appropriate technique to use in patients with previous cesarean sections. This study evaluated the feasibility of the Misgav-Ladach technique in patients with previous cesarean sections. STUD...
journal_title：American journal of perinatology
pub_type： 临床试验,杂志文章
doi：10.1055/s-0032-1323580
更新日期：2013-03-01 00:00:00
abstract：:Molecular amplification of parvovirus B19 DNA in an amniotic fluid sample was used to confirm the etiologic agent of a case with fetal hydrops. The polymerase chain reaction (PCR) method used is easy and fast to perform. We have a 2-year experience on its use in clinical parvovirus B19 diagnosis. The results are avail...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-994518
更新日期：1995-11-01 00:00:00
abstract：:Limited research in young adults and immature animals suggests a detrimental effect of tobacco on bone during growth. We aimed to determine the adverse effects of maternal nicotine exposure during pregnancy and lactation on neonatal rat bone development, and to determine a protective effect of ascorbic acid. Gravid ra...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2006-951287
更新日期：2006-10-01 00:00:00
abstract：:The objective of this article is to evaluate the plasma levels of coagulation and fibrinolysis parameters in the third trimester of gestation and 72 hr postdelivery. Antithrombin III (ATIII), thrombin-antithrombin III complexes (TAT), heparin cofactor II (HCII), protein C (PC), protein S (PS), tissue plasminogen activ...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-993903
更新日期：1998-02-01 00:00:00
abstract：:We report about two newborns with sudden onset of inability of mechanical ventilation due to transient chest wall rigidity after fentanyl i.v. bolus of 2 and 4 microg/kg, respectively, resulting in severe hypoxemia and secondary bradycardia. A third case developed a rigidity of the tongue after fentanyl bolus, which c...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2000-7289
更新日期：2000-01-01 00:00:00
abstract：OBJECTIVE:The objective of this study was to assess whether the location of the trocar insertion site for laser treatment of twin-twin transfusion syndrome was associated with preterm-premature rupture of membranes (PPROM) and preterm birth (PTB). STUDY DESIGN:In this study trocar location was documented in the operat...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0037-1620268
更新日期：2018-07-01 00:00:00
abstract：:The objective of this paper is to determine whether acyclovir suppression provides a greater cost savings over no medical therapy in the management of recurrent genital herpes (HSV) in pregnancy. Estimates of the risk of HSV recurrence and cesarean delivery rates in acyclovir-treated and -untreated patients and freque...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-993900
更新日期：1998-01-01 00:00:00
abstract：OBJECTIVE:To analyze outcomes after second-stage labor beyond 3 hours and determine if prolonged second stages were intentional. STUDY DESIGN:Retrospective cohort analysis of maternal and neonatal outcomes in nulliparous women based on second-stage duration. Medical records were reviewed for management decisions in wo...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0032-1314894
更新日期：2012-10-01 00:00:00
abstract：OBJECTIVE: Delayed maturation of auditory brainstem pathway in neonates admitted to the neonatal intensive care unit (NICU) may lead to misdiagnosis of children with normal peripheral hearing and inappropriate use of amplification devices. The aim of this study is to determine the pattern of auditory brain stem respons...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0040-1709467
更新日期：2020-04-10 00:00:00
abstract：OBJECTIVE:The aim of this study is to describe the changes in term fetal heart tracings after magnesium exposure. MATERIALS AND METHODS:This was a retrospective cohort study of consecutive women delivering at a gestational age of ≥ 37 weeks with severe preeclampsia, receiving magnesium for seizure prophylaxis. Overall...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0033-1363499
更新日期：2014-11-01 00:00:00
abstract：:The significance and management of prepartum bradycardia is not well established in prepartum fetal assessment. The incidence of prolonged bradycardia was 3.5% (45 per 1284), defined as a decrease of greater than or equal to 40 beats per minute of the fetal heart rate (FHR) below the baseline for at least 2 minutes. T...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-999972
更新日期：1985-10-01 00:00:00
abstract：BACKGROUND:Bacillus Calmette-Guerin (BCG) scar formation is considered a visual marker of vaccination and cell-mediated immune response. This study characterized the association between pregnancy and birth characteristics with BCG scar formation. STUDY DESIGN:Pregnant women were enrolled prospectively. Infants were fo...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0038-1676614
更新日期：2019-10-01 00:00:00
abstract：:Osteomyelitis is rarely complicated by an infected cephalohematoma. We report a case of an infected cephalohematoma associated with Escherichia coli sepsis and osteomyelitis of the skull. This 37-day-old boy had E. coli sepsis, which had a poor response to antibiotic treatment. An infected cephalohematoma was found wh...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-1999-6803
更新日期：1999-01-01 00:00:00
abstract：OBJECTIVE:The aim of this study is to evaluate the impact of multiple pregnancies, maternal obesity, and preeclampsia on the effect of antenatal steroids on neonatal respiratory distress syndrome (RDS). STUDY DESIGN:The retrospective cohort study was performed in a level III maternity ward. Population was composed of ...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0035-1548537
更新日期：2015-09-01 00:00:00
abstract：:Background Late-onset sepsis (LOS) in very low-birth-weight (VLBW) infants is associated with significant morbidity and mortality. Objectives To determine the incidence of LOS workup, association, and predictive value of clinical indicators leading to culture-positive versus culture-negative sepsis workup. Methods All...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0036-1579648
更新日期：2016-07-01 00:00:00
abstract：OBJECTIVE:We have previously shown a decrease in the overall stillbirth rate at our institution in women receiving the seasonal influenza vaccine during pregnancy. The goal of this study was to ascertain factors associated with this decrease. STUDY DESIGN:This was a retrospective cohort study examining the stillbirth ...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0034-1544046
更新日期：2015-05-01 00:00:00
abstract：OBJECTIVE:To determine whether 17-α-hydroxyprogesterone caproate (17P) reduces the incidence of preterm birth in women with a history-indicated cerclage. STUDY DESIGN:Retrospective cohort study of women who received a cerclage for a prior preterm birth, analyzed based on exposure to 17P. The primary outcome variable w...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0032-1332799
更新日期：2013-10-01 00:00:00
abstract：INTRODUCTION:Many tertiary neonatal units employ a restricted visiting policy. Webcams have previously been implemented in the neonatal unit setting in several countries. OBJECTIVES:This study aims to determine the views from parents, physicians, and nursing staff before implementation of a webcam system. METHODS:A q...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0034-1376388
更新日期：2015-02-01 00:00:00
abstract：:We determined the glycemic response to intravenous lipid infusion alone, lipid with amino acids, or amino acids alone in 15 very small premature infants receiving constant glucose infusion during early life. Infants who received lipid or lipid and amino acids demonstrated significant increases in glucose compared with...
journal_title：American journal of perinatology
pub_type： 临床试验,杂志文章
doi：10.1055/s-2007-999685
更新日期：1988-07-01 00:00:00
abstract：OBJECTIVE:To evaluate if fundal (F) dominance of the electrohysterogram is associated with vaginal delivery and lack of F dominance is associated with cesarean for labor dystocia. STUDY DESIGN:We conducted a prospective cohort study of nulliparous women in spontaneous labor at ≥36 weeks. Clinicians were blinded to ele...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0038-1675621
更新日期：2019-07-01 00:00:00
abstract：:Chorioamnionitis has generally been thought to be a contraindication to attempting a delayed interval delivery in a multiple gestation. We present a twin gestation in which a delay of 88 days between the birth of the two infants occurred. Chorioamnionitis observed immediately after the delivery of Twin A was successfu...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-993962
更新日期：1998-06-01 00:00:00
abstract：:The novel coronavirus disease 2019 (COVID-19) pandemic has resulted in changes to perinatal and neonatal care, concentrating on minimizing risks of transmission to the newborn and health care staff while ensuring medical care is not compromised for both mother and infant. Current recommendations on infant care and fee...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0040-1716506
更新日期：2020-11-01 00:00:00
abstract：:The purpose of this study was to evaluate the feasibility of the use oral ibuprofen suspension (OIS) in the treatment of patent ductus arteriosus (PDA) in premature infants. Premature infants (
journal_title：American journal of perinatology
pub_type： 杂志文章,随机对照试验
doi：10.1055/s-2007-976550
更新日期：2007-05-01 00:00:00
