Abstract:
:Conventional interval dosing (CID) and extended interval dosing (EID) of gentamicin were compared in preterm infants. Gentamicin peak and trough levels, serum creatinine, urine output, and hearing screens were obtained in 40 preterm infants. Results suggest that EID is safe, provides gentamicin levels in desirable ranges (peak, 5 to 12 microg/mL; trough < 2 microg/mL), and reduces dosage adjustments.
journal_name
Am J Perinatoljournal_title
American journal of perinatologyauthors
Mercado MC,Brodsky NL,McGuire MK,Hurt Hdoi
10.1055/s-2004-820515subject
Has Abstractpub_date
2004-02-01 00:00:00pages
73-7issue
2eissn
0735-1631issn
1098-8785journal_volume
21pub_type
临床试验,杂志文章,随机对照试验abstract:OBJECTIVE: The acylcarnitine profile is analyzed in dried blood spots (DBS) to screen for inborn errors of metabolism. Hematocrit (Ht) is known to affect the result of quantitative analyses of DBS samples; however, the effects of Ht on the acylcarnitine profiles in DBS have not been studied in actual samples from newbo...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0040-1721849
更新日期:2020-12-29 00:00:00
abstract::The aim of this study was to compare the pregnancy outcome and delivery complications in women 40 years or older (cases) to that of women 20 to 30 years old (controls). Over a 5-year period, 319 cases had a singleton delivery in our institution. These women were compared with 326 controls. Parity was significantly hig...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2002-20175
更新日期:2002-01-01 00:00:00
abstract:OBJECTIVE:This study aims to develop a scoring system for the prediction of bronchopulmonary dysplasia (BPD). METHODS:Medical records of 652 infants whose gestational age and birth weight were below 32 weeks and 1,500 g, respectively, and who survived beyond 28th postnatal day were reviewed retrospectively. Logistic r...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0034-1393935
更新日期:2015-06-01 00:00:00
abstract:OBJECTIVE:Prediction of gestational latency after placement of physical exam indicated cerclage (PEIC) is limited. Uterocervical angle (UCA) has been associated with spontaneous preterm delivery in the general population. Our objective was to examine whether UCA is associated with gestational latency in women with PEIC...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0037-1621734
更新日期:2018-07-01 00:00:00
abstract::In Finland a nationwide free prenatal care system was mandated by law in 1944. At present, 99.9% of Finland's pregnant women use it. The primary aim is to provide advice and care to all women in local centers and to identify pregnant women exhibiting risk factors and refer them to specialized prenatal units located in...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-999581
更新日期:1989-04-01 00:00:00
abstract::We describe the neuropathologic procedure utilized in the Stillbirth Collaborative Research Network (SCRN), focusing on the examination of central nervous system (CNS) in stillbirth (SB). The SCRN was organized to perform a case-control study to determine the scope and causes of SB. Pathologists at all the participati...
journal_title:American journal of perinatology
pub_type: 杂志文章,多中心研究
doi:10.1055/s-0031-1284229
更新日期:2011-12-01 00:00:00
abstract:OBJECTIVE:This study aimed to evaluate if maternal serum hormones along the maternal-fetal hypothalamic-pituitary-adrenal (HPA) axis, when drawn prior to labor induction, differed between women who delivered vaginally and those who underwent cesarean. STUDY DESIGN:This was a prospective observational study at a single...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0040-1708801
更新日期:2020-10-01 00:00:00
abstract::Placental pathology in preeclampsia (PE) and intrauterine growth retardation (IUGR) is associated with alterations of the placental epidermal growth factor receptor (EGFR). It is encoded by a single gene, which gives rise to two different full-length transcripts and one putative truncated transcript in the placenta. T...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-993890
更新日期:1998-01-01 00:00:00
abstract::We examined the frequency with which congenital heart disease (CHD) and cytogenetic abnormalities were found associated with omphalocele, gastroschisis, duodenal atresia and posterior diaphragmatic hernias. We performed fetal echocardiograms on 80 patients with these diagnoses and found congenital heart disease in 13 ...
journal_title:American journal of perinatology
pub_type: 杂志文章,评审
doi:10.1055/s-2007-999427
更新日期:1991-11-01 00:00:00
abstract::Our objective was to determine if sonographic estimate of fetal weight (SEFW) can identify fetal growth restriction (FGR; birthweight < 10% for gestational age [GA]) among patients with preterm (28 to 32 weeks) severe preeclampsia (P SPE). At two centers, all singletons with reliable GA, P SPE, and SEFW within 3 weeks...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2008-1075034
更新日期:2008-04-01 00:00:00
abstract::Introduction First-trimester ultrasound (US) for anatomy assessment may improve anomaly detection, but it may also increase overall US utilization. We sought to assess the utility of first-trimester US for evaluation of fetal anatomy. Materials and Methods A decision analytic model was created to compare first- plus s...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0036-1579652
更新日期:2016-08-01 00:00:00
abstract::The objective of this article is to report obstetric outcomes of human immunodeficiency virus-1 (HIV-1)-serodiscordant couples who underwent in vitro fertilization and embryo transfer (IVF-ET) with intracytoplasmic sperm injection (ICSI) at a tertiary care center. We reviewed the outcomes of seronegative women after I...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2003-42694
更新日期:2003-08-01 00:00:00
abstract::The most frequently used set of gestational age-birth weight curves in the United States is the Colorado (C) standard published in 1963. To investigate the usefulness of this standard in an urban population at sea level, we examined the birth weight vs gestational age data from 56,675 singleton liveborn infants born b...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-999785
更新日期:1987-07-01 00:00:00
abstract:OBJECTIVE:There is limited research exploring the relationship between design and patient safety outcomes, especially in maternal and neonatal care. We employed design thinking methodology to understand how the design of labor and delivery units impacts safety and identified spaces and systems where improvements are ne...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0039-1685494
更新日期:2020-05-01 00:00:00
abstract::The significance and management of prepartum bradycardia is not well established in prepartum fetal assessment. The incidence of prolonged bradycardia was 3.5% (45 per 1284), defined as a decrease of greater than or equal to 40 beats per minute of the fetal heart rate (FHR) below the baseline for at least 2 minutes. T...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-999972
更新日期:1985-10-01 00:00:00
abstract:OBJECTIVE:To review developmental outcomes of neonates with mild hypoxic-ischemic encephalopathy (HIE) treated with therapeutic hypothermia (TH). STUDY DESIGN:Neonates ≥35 weeks' gestation with mild HIE/TH (TH group, n = 30) were matched with healthy term-born infants (control group, n = 30) and reviewed for the prese...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0038-1676973
更新日期:2019-11-01 00:00:00
abstract:OBJECTIVES:To describe the trend and factors associated with the autopsy over the past decade at a level III neonatal intensive care unit (NICU) where all patients are presented with an option. STUDY DESIGN:Retrospective study of the autopsy in a cohort of infants who died in the NICU from January 1, 2001, to December...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0032-1332798
更新日期:2013-10-01 00:00:00
abstract::Introduction Bronchopulmonary dysplasia (BPD) is a frequent, long-term complication in very low-birth-weight (VLBW) newborns. Its etiology is multifactorial and the oxidative stress is one of its main causes. Breast milk (BM) reduces oxidative stress and provides antioxidant protection, therefore, BM may have a protec...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0036-1586503
更新日期:2017-02-01 00:00:00
abstract::The estimation of plasma bilirubin concentration in neonates, using a transcutaneous, noninvasive jaundice meter, is significantly affected by many factors, such as gestational age, birthweight, phototherapy, and skin pigmentation. In an attempt to minimize the influence of skin color and hence circumvent the need for...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2008-1040751
更新日期:1994-05-01 00:00:00
abstract:OBJECTIVE:We investigated the association between gestational weight gain (GWG) and postpartum depression (PPD) in women with class III obesity. STUDY DESIGN:This is a retrospective cohort of women with body mass index (BMI) ≥ 40 kg/m2 at entry to care, first prenatal visit ≤14 weeks gestation, with singleton, nonanom...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0039-1693989
更新日期:2020-01-01 00:00:00
abstract::Ehlers-Danlos syndrome type IV (EDS IV) is a rare but serious disorder of connective tissue that is characterized by the abnormal production or secretion of type III collagen. Experience with pregnant patients exhibiting this syndrome is limited. This report describes the successful management of a pregnancy in a woma...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-999756
更新日期:1987-04-01 00:00:00
abstract::The objective of this article is to prospectively investigate the efficacy of amnioinfusion as a means to reduce febrile morbidity in pregnancies complicated by chorioamnionitis. All laboring patients with a temperature > or =100.1 degrees F were approached for study participation. Exclusion criteria included amnionit...
journal_title:American journal of perinatology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1055/s-2007-994085
更新日期:1998-01-01 00:00:00
abstract:OBJECTIVE: It is well established that women with a previous vaginal delivery have higher success rates in relation to vaginal birth after cesarean than those without. The aim of this study was to examine the effect of past mode of delivery on contractile parameters of human myometrium in vitro. STUDY DESIGN: Myometri...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0039-1694980
更新日期:2021-01-01 00:00:00
abstract:OBJECTIVE:The Apgar score has been shown to have utility in predicting mortality in the extremely preterm infant in delivery hospital populations, where most mortality occurs within 12 hours of birth. We tested the hypothesis that the 5 minute Apgar score would remain associated with mortality in extremely preterm infa...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0035-1554803
更新日期:2015-11-01 00:00:00
abstract::Although cesarean section is one of the most ancient surgical procedures, the origin of its name remains obscure. The term, however, did not originate because of the birth of the Roman Emperor Julius Caesar through this route. In fact, historians are certain that Julius Caesar was not delivered by the dangerous cesare...
journal_title:American journal of perinatology
pub_type: 历史文章,杂志文章
doi:10.1055/s-2007-986693
更新日期:2007-11-01 00:00:00
abstract:OBJECTIVE:Systemic lupus erythematosus (SLE) increases the risk of complications in pregnancy. Hydroxychloroquine (HCQ) decreases flares and neonatal lupus syndrome. Limited evidence suggests that HCQ also reduces preeclampsia and preterm birth in SLE pregnancies. We studied whether HCQ was associated with lower odds o...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0039-3402752
更新日期:2020-07-01 00:00:00
abstract:OBJECTIVE:The aim of the study is to determine if umbilical cord serum concentrations of interleukin-6 (IL-6), C-reactive protein (CRP), and myeloperoxidase (MPO), in pregnancies at risk for preterm birth (PTB), are associated with neonatal morbidities and/or altered neurodevelopmental outcomes in the children. STUDY ...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0033-1359723
更新日期:2014-09-01 00:00:00
abstract:UNLABELLED:We evaluated the effectiveness of oral misoprostol for outpatient cervical ripening and labor induction in prolonged pregnancies. We performed a randomized, double-blind, placebo-controlled study of women at 40 to 42 weeks' gestation with well-dated pregnancies, singleton gestations, Bishop scores less than ...
journal_title:American journal of perinatology
pub_type: 杂志文章,随机对照试验
doi:10.1055/s-0029-1220790
更新日期:2009-10-01 00:00:00
abstract:OBJECTIVE:Our objective was to evaluate the efficacy of perioperative multimodal pain management in reducing opioid use after elective cesarean delivery (CD). STUDY DESIGN:A single-center, double-blinded, placebo-controlled randomized trial of women undergoing elective CD. Participants were allocated 1:1 to receive th...
journal_title:American journal of perinatology
pub_type: 杂志文章,随机对照试验
doi:10.1055/s-0039-1681096
更新日期:2019-09-01 00:00:00
abstract::We sought to determine the incidence of cord entanglement around any part of fetal body during early gestation using three-dimensional (3D) sonography. A prospective consecutive study was designed and 3D ultrasound was performed. Two hundred thirty-seven singleton pregnancies between 13 and 16 weeks were included. Cor...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0028-1110090
更新日期:2009-05-01 00:00:00