Abstract:
:A patient with congenital antithrombin III deficiency and a history of thromboembolic events prior to pregnancy was successfully treated with subcutaneous heparin alone throughout two pregnancies. Although adjuvant antithrombin III infusions may have a role in the treatment of this disorder, especially in the peripartum period, there is no evidence that this approach is superior to heparin therapy alone. We present this case as further evidence that heparin therapy alone appears to be a safe and effective treatment for pregnant patients with this rare but serious disorder.
journal_name
Am J Perinatoljournal_title
American journal of perinatologyauthors
Neerhof MG,Krewson DP,Haut M,Librizzi RJdoi
10.1055/s-2007-994748subject
Has Abstractpub_date
1993-07-01 00:00:00pages
311-2issue
4eissn
0735-1631issn
1098-8785journal_volume
10pub_type
杂志文章abstract:OBJECTIVE:We investigated the association between gestational weight gain (GWG) and postpartum depression (PPD) in women with class III obesity. STUDY DESIGN:This is a retrospective cohort of women with body mass index (BMI) ≥ 40 kg/m2 at entry to care, first prenatal visit ≤14 weeks gestation, with singleton, nonanom...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0039-1693989
更新日期:2020-01-01 00:00:00
abstract:OBJECTIVE:To analyze outcomes after second-stage labor beyond 3 hours and determine if prolonged second stages were intentional. STUDY DESIGN:Retrospective cohort analysis of maternal and neonatal outcomes in nulliparous women based on second-stage duration. Medical records were reviewed for management decisions in wo...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0032-1314894
更新日期:2012-10-01 00:00:00
abstract:OBJECTIVE: This study aimed to determine whether outcomes differed between infants enrolled in the PREMOD2 trial and those otherwise eligible but not enrolled, and whether the use of waiver effected these differences. STUDY DESIGN: The multicenter PREMOD2 (PREmature infants receiving Milking Or Delayed cord clamping) ...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0040-1719184
更新日期:2020-11-03 00:00:00
abstract::Cord blood gas determinations were made on arterial and venous blood from 78 babies weighing less than 2000 gm at birth, including 52 weighing 1500 gm or less. Correlations were made with Apgar scores and intrapartum events as well as with birthweight (BW) and gestational age (GA). Significant differences were seen be...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-999925
更新日期:1985-04-01 00:00:00
abstract::With more than 20,000 fetal deaths occurring annually in the United States, accurate epidemiological data concerning fetal death offer the potential to develop interventions aimed at saving a considerable number of fetuses. Currently, fetal death rates are determined by dividing the number of deaths by total births. T...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-994589
更新日期:1994-07-01 00:00:00
abstract::Objective To compare maternal birth complications early versus late in the academic year and to evaluate the impact of resident work hour limitation on the "July effect." Study Design We conducted a retrospective, population-based cohort study of 628,414 singleton births in Washington State from 1987 to 2012 measuring...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0037-1598244
更新日期:2017-07-01 00:00:00
abstract::Classically, genetically decreased bilirubin conjugation and/or hemolysis account for the mechanisms contributing to neonatal hyperbilirubinemia associated with glucose-6-phosphate dehydrogenase (G6PD) deficiency. However, these mechanisms are not involved in most cases of this hyperbilirubinemia. Additional plausible...
journal_title:American journal of perinatology
pub_type: 杂志文章,评审
doi:10.1055/s-0036-1585465
更新日期:2017-02-01 00:00:00
abstract::Background It is unclear how adherence to the Institute of Medicine's (IOM) guidelines for weight gain affects pregnancy outcomes. Objective We investigated how weight gain outside the IOM's recommendations affects the risks of adverse pregnancy outcomes. Study Design We performed a secondary analysis of a prospective...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0036-1584583
更新日期:2017-01-01 00:00:00
abstract::The aim of this study was to compare the pregnancy outcome and delivery complications in women 40 years or older (cases) to that of women 20 to 30 years old (controls). Over a 5-year period, 319 cases had a singleton delivery in our institution. These women were compared with 326 controls. Parity was significantly hig...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2002-20175
更新日期:2002-01-01 00:00:00
abstract::Pleural effusion is not an uncommon complication of percutaneous intravenous catheters in neonates. Umbilical venous catheters (UVCs) are associated with pleural effusion following abnormal placement in the left atrium or pulmonary veins due to venous obstruction. We report for the first time a case of right-sided ple...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-992174
更新日期:2007-11-01 00:00:00
abstract::Progress in neonatal care has decrease morbidity and mortality due to neonatal sepsis (NS). Although diagnosis of sepsis continues to rely on blood culture, this method is too slow and limited by false-negative results. There are numerous sepsis biomarkers that have been evaluated for the early diagnosis of NS, but, t...
journal_title:American journal of perinatology
pub_type: 杂志文章,评审
doi:10.1055/s-0038-1639361
更新日期:2018-05-01 00:00:00
abstract::The ultrastructural architecture of colostral cells of mothers of pre- and full-term infants is described. The polymorphonuclears were engaged in vivid phagocytosis of fat droplets. Similar findings were observed on the macrophages. The lymphocytes appeared normal in size and ultrastructure. A small number of eosinoph...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-994162
更新日期:1997-07-01 00:00:00
abstract::The pregnant woman with idiopathic thrombocytopenic purpura (ITP) and her fetus-neonate present a number of challenging issues for both the perinatologist and neonatologist. A review of these issues within a single format is helpful because of the widely scattered nature of the pertinent information in the medical lit...
journal_title:American journal of perinatology
pub_type: 杂志文章,评审
doi:10.1055/s-2007-1000014
更新日期:1984-04-01 00:00:00
abstract::The purpose of this study was to evaluate the feasibility of the use oral ibuprofen suspension (OIS) in the treatment of patent ductus arteriosus (PDA) in premature infants. Premature infants (= 35 weeks) age 2 to 7 days who suffered from respiratory distress and had been diagnosed with PDA were included in this stu...
journal_title:American journal of perinatology
pub_type: 杂志文章,随机对照试验
doi:10.1055/s-2007-976550
更新日期:2007-05-01 00:00:00
abstract::During normal pregnancy there is a decrease in the hematocrit due to a disproportionate increase in the blood volume compared with the red cell mass. Using a new enzyme-linked immunoassay (Amgen Diagnostics), serum erythropoietin was quantified in normal nonanemic pregnancies throughout gestation and in third trimeste...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-994778
更新日期:1992-07-01 00:00:00
abstract::Objectives This study aims to examine the relationship between hospital birth volume and multiple maternal morbidities among low-risk pregnancies in rural hospitals, urban non-teaching hospitals, and urban teaching hospitals, using a representative sample of U.S. hospitals. Study Design Using the 2011 Nationwide Inpat...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0035-1570380
更新日期:2016-05-01 00:00:00
abstract::In the present study we examined whether the vitamin D3 metabolites, 25-hydroxyvitamin D and 1-25-dihydroxycholecalciferol affected the production of the prostaglandins PGE2 and PGF2 alpha in human fetal membranes and placenta in vitro. Human amnion, chorion, decidual, and placental cells were maintained in primary mo...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-999564
更新日期:1989-04-01 00:00:00
abstract::Hypertensive disorders during pregnancy implicate placental pathologic conditions, which may interfere with the normal passage of alpha-fetoprotein (AFP) to the maternal blood. We compared the levels of maternal serum (MS) in early second trimester of pregnancies complicated by hypertensive disorders with those of mat...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-999254
更新日期:1992-09-01 00:00:00
abstract::Intra-amniotic infection is often the cause of a second-trimester abortion. The bacterial species involved include bacteria with low pathogenicity like Ureaplasma urealyticum and various Mycoplasma species. In this case we describe an intra-amniotic infection caused by Capnocytophaga sputigena, often found in the norm...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-993854
更新日期:1999-01-01 00:00:00
abstract::Preeclampsia is uncommon prior to 24 weeks gestation and has been associated with partial and complete hydatidiform moles. We present an unusual case in which a patient was diagnosed with preeclampsia at 17 weeks gestation. Ultrasound findings were consistent with a partial hydatidiform mole. Within 24 hours of the on...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2006-934093
更新日期:2006-04-01 00:00:00
abstract:OBJECTIVE:This study aims to evaluate vaginal microbiota differences by bacterial vaginosis (BV), birth timing, and race, and to estimate parameters to power future vaginal microbiome studies. METHODS:Previously, vaginal swabs were collected at 21 to 25 weeks (stored at -80°C), and vaginal smears evaluated for BV (Nug...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0035-1565919
更新日期:2016-03-01 00:00:00
abstract::Acute mitral regurgitation due to ruptured chordae tendineae is a dramatic and life-threatening clinical situation. Rarely does this complication occur during pregnancy. We present a case of a 30-year-old woman in week 31 of her pregnancy who developed acute mitral regurgitation, secondary to bacterial endocarditis an...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-994418
更新日期:1995-03-01 00:00:00
abstract:OBJECTIVE:We sought to determine if maternal prepregnancy body mass index (BMI) is a risk factor for neonatal respiratory morbidity and to determine if increasing BMI decreased the efficacy of betamethasone (BMZ). STUDY DESIGN:This was a secondary analysis of the Antenatal Late Preterm Steroids trial, double-blind, ra...
journal_title:American journal of perinatology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1055/s-0039-1696644
更新日期:2020-03-01 00:00:00
abstract::To study a possible relation between the use of postnatal glucocorticoids and the incidence and severity of retinopathy of prematurity (ROP), we conducted a retrospective study over a 4-year period that compared data of 161 preterm infants treated with hydrocortisone for bronchopulmonary dysplasia (BPD) with the data ...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2000-13437
更新日期:2000-01-01 00:00:00
abstract::Caffeine is commonly used in the treatment of apnea of prematurity. The skin of preterm infants varies considerably in its level of maturity. To understand skin absorption in low birthweight infants (less than 1500 gm) with gestational age between 26 and 34 weeks, a group of 56 preterm babies was studied after percuta...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-999282
更新日期:1992-09-01 00:00:00
abstract::Five full term infants with necrotizing enterocolitis, confirmed histologically, presented in the first five days of life. All passed grossly bloody stools and three mucosal casts. Severe perinatal asphyxia with accompanying secondary hyperammonemia was present in all, and abnormal liver function studies were present ...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-1000050
更新日期:1983-10-01 00:00:00
abstract::This report describes 40 consecutive emergency cerclages on dilated and effaced cervices prior to 26 weeks' gestation. These "emergency" cerclages were associated with a mean extension of gestational age of 12 weeks (range, 3 days to 20.5 weeks). Thirty-one of 40 pregnancies were carried to 28 weeks' gestation and 23 ...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-999307
更新日期:1992-05-01 00:00:00
abstract::Presented are three cases of fetal death, all of which occurred within 3 days of a normal biophysical profile. Despite the excellent record of this antepartum test in predicting fetal well-being, there is a low incidence of false-negative tests; increasing the frequency of testing will not prevent all false-negative t...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-999352
更新日期:1991-03-01 00:00:00
abstract::We present a rare occurrence of an early-onset extensive cystic hygroma colli with intralesional hemorrhage and a favorable outcome. A 23-year-old primigravida woman was referred for management of a left isolated extensive cystic hygroma colli at 22 weeks' gestation. Amniocentesis revealed a 46, XY karyotype. Ultrasou...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-994077
更新日期:1998-01-01 00:00:00
abstract::This communication examines the diagnostic value of the leukocyte esterase activity (LEA) test in the detection of intra-amniotic infection. Amniotic fluid from 171 consecutive patients with premature rupture of membranes (n = 149) and preterm labor (n = 22) was obtained through amniocentesis. Gram stain, bacterial an...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-999657
更新日期:1988-01-01 00:00:00