Abstract：
:To study a possible relation between the use of postnatal glucocorticoids and the incidence and severity of retinopathy of prematurity (ROP), we conducted a retrospective study over a 4-year period that compared data of 161 preterm infants treated with hydrocortisone for bronchopulmonary dysplasia (BPD) with the data of 253 controls. The incidence of overall ROP was 62.7% in the hydrocortisone group and 21.3% in the control group. The incidence of severe ROP (stages 3-5) was 5% in the treatment group and 0.4% in the control group. Using logistic regression, postnatal hydrocortisone therapy was not associated with an increased risk for ROP or severe ROP (OR 1.387, 95% confidence interval 0.773-2.489, p = 0.272 and OR 4.112, 95% C.I. 0.44-38.37, p = 0.16, respectively). Also, in a subgroup of extremely low-birth-weight infants (<1000 g), postnatal hydrocortisone had no influence on the incidence of (severe) ROP. In the infants with ROP (n = 155), only prolonged use of postnatal hydrocortisone was associated with an increased risk for severe ROP (OR 1.02, 95% C.I. 1.00-1.03, p = 0.03). In this study postnatal use of hydrocortisone was not associated with an increased risk for (severe) ROP. However, in infants already suffering from ROP, prolonged treatment with hydrocortisone concurred with an increased risk for severe ROP.
journal_name
Am J Perinatoljournal_title
American journal of perinatologyauthors
Termote J,Schalij-Delfos NE,Donders AR,Cats BPdoi
10.1055/s-2000-13437subject
Has Abstractpub_date
2000-01-01 00:00:00pages
291-8issue
6eissn
0735-1631issn
1098-8785journal_volume
17pub_type
杂志文章abstract：OBJECTIVE: Potentially avoidable maternity complications (PAMCs) have been validated as an indicator of access to quality prenatal care. African-American mothers have exhibited a higher incidence of PAMCs, which has been attributed to unequal health coverage. The objective of this study was to assess if racial disparit...
journal_title：American journal of perinatology
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abstract：:We have examined the safety and efficacy of an early postpartum discharge program in 289 patients who were identified prior to delivery and counseled and educated for discharge 12 to 36 hours after delivery. A total of 55% of the study patients were able to be discharged early. There were 4.3% significant maternal pro...
journal_title：American journal of perinatology
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pub_type： 杂志文章,多中心研究,随机对照试验
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journal_title：American journal of perinatology
pub_type： 杂志文章
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journal_title：American journal of perinatology
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更新日期：2019-12-01 00:00:00
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journal_title：American journal of perinatology
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更新日期：1989-10-01 00:00:00
