Diagnosis of preterm rupture of membranes: is testing for alpha-fetoprotein better than ferning or nitrazine?

Abstract:

:This article evaluates the role of alpha-fetoprotein (AFP) testing in the diagnosis of ruptured membranes in the preterm patient. AFP is normally found in amniotic fluid and is not present in vaginal secretions. Testing for AFP in vaginal fluid was compared with nitrazine evaluation and ferning in two groups of preterm patients, those with intact membranes and those with ruptured membranes. There was no difference in the sensitivities of AFP, nitrazine, or ferning in diagnosing ruptured membranes. The specificities of AFP and ferning were similar and both were significantly better than nitrazine. Duration of membrane rupture for greater than 24 hours negatively affected the accuracy of all three tests. Blood-tinged amniotic fluid interfered with AFP and nitrazine evaluation. AFP does not appear to offer a significant advantage over nitrazine testing and ferning in the evaluation of patients with possible ruptured membranes.

journal_name

Am J Perinatol

authors

Garite TJ,Gocke SE

doi

10.1055/s-2007-999500

subject

Has Abstract

pub_date

1990-07-01 00:00:00

pages

276-8

issue

3

eissn

0735-1631

issn

1098-8785

journal_volume

7

pub_type

杂志文章
  • Vaginal birth after cesarean delivery in a small rural community with a solo practice.

    abstract::The objective of this study is to review the safety and success of a trial of labor after cesarean in a group of patients managed by a solo practitioner in a rural community. This was a retrospective review of all deliveries performed over an 11-year period by a single practitioner in a rural community. Standard contr...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-2003-38317

    authors: Upadhyaya CD,Upadhyaya DM,Carlan SJ

    更新日期:2003-02-01 00:00:00

  • The very low birthweight infant: incidence and significance of low Apgar scores, "asphyxia," and morbidity. Findings at delivery.

    abstract::Cord blood gas determinations were made on arterial and venous blood from 78 babies weighing less than 2000 gm at birth, including 52 weighing 1500 gm or less. Correlations were made with Apgar scores and intrapartum events as well as with birthweight (BW) and gestational age (GA). Significant differences were seen be...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-2007-999925

    authors: Perkins RP,Papile LA

    更新日期:1985-04-01 00:00:00

  • A Multicentered Randomized Study on Early versus Rescue Calsurf Administration for the Treatment of Respiratory Distress Syndrome in Preterm Infants.

    abstract:OBJECTIVE:Surfactant and noninvasive ventilation are two major strategies for the treatment of neonates with respiratory distress syndrome (RDS). However, the optimal time for surfactant administering is yet controversial. This study compared the early and rescue Calsurf administration in preterm infants with RDS. STU...

    journal_title:American journal of perinatology

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1055/s-0039-1678530

    authors: Rong Z,Chang L,Cheng H,Wang H,Zhu X,Peng F,Fan Q,Lu W,Pan R,Xiong L,Jiao R,Sun J,Xia S,Xie J

    更新日期:2019-12-01 00:00:00

  • Does Ventilatory Time Retain Its Validity in Predicting Neurodevelopmental Outcome at Two Years of Age in High-Risk Congenital Diaphragmatic Hernia Survivors?

    abstract::Objective To evaluate if in high-risk non-extracorporeal membrane oxygenation (ECMO)-treated congenital diaphragmatic hernia (CDH) survivors, ventilatory time (VT) is correlated to and can be used as clinical marker of neurodevelopmental delay at 2 years of age. Study Design Cohort study was conducted between 2008 and...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-0036-1586120

    authors: Bevilacqua F,Morini F,Zaccara A,Valfrè L,Aufiero LR,Gentile S,Bagolan P,Aite L

    更新日期:2017-02-01 00:00:00

  • Changes in fetal heart tracing characteristics after magnesium exposure.

    abstract:OBJECTIVE:The aim of this study is to describe the changes in term fetal heart tracings after magnesium exposure. MATERIALS AND METHODS:This was a retrospective cohort study of consecutive women delivering at a gestational age of ≥ 37 weeks with severe preeclampsia, receiving magnesium for seizure prophylaxis. Overall...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-0033-1363499

    authors: Stewart AM,Macones GA,Odibo AO,Colvin R,Cahill AG

    更新日期:2014-11-01 00:00:00

  • Use of noninvasive high-frequency ventilation in the neonatal intensive care unit: a retrospective review.

    abstract:OBJECTIVE:The aim of the article is to review the effectiveness of neonatal noninvasive high-frequency ventilation (NIHFV) in preventing endotracheal mechanical ventilation. STUDY DESIGN:Retrospective case series including all 79 instances of NIHFV use at four participating centers between July 2010 and September 2012...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-0034-1381317

    authors: Mukerji A,Singh B,Helou SE,Fusch C,Dunn M,Belik J,Shah V

    更新日期:2015-02-01 00:00:00

  • Impact of the New American Hypertension Guidelines on the Prevalence of Postpartum Hypertension.

    abstract::Cardiovascular disease (CVD) is the leading cause of death and disability among women, with more than half occurring in individuals with hypertension. New blood pressure criteria for the diagnosis of hypertension from the American College of Cardiology/American Heart Association recognize that there is no specific blo...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-0038-1669441

    authors: Smith GN,Pudwell J,Saade GR

    更新日期:2019-03-01 00:00:00

  • A prospective controlled trial of albuterol aerosol delivered via metered dose inhaler-spacer device (MDI) versus jet nebulizer in ventilated preterm neonates.

    abstract::The objective of this study was to identify the most efficient and cost-effective nebulizer device for delivery of albuterol aerosol as a bronchodilator in ventilated preterm infants. Bronchodilators are frequently used as part of the therapeutic regimen of ventilated preterm infants. This can be delivered by differen...

    journal_title:American journal of perinatology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1055/s-2001-14526

    authors: Khalaf MN,Hurley JF,Bhandari V

    更新日期:2001-05-01 00:00:00

  • Labor and delivery complicated by acute mitral regurgitation due to ruptured chordae tendineae.

    abstract::Acute mitral regurgitation due to ruptured chordae tendineae is a dramatic and life-threatening clinical situation. Rarely does this complication occur during pregnancy. We present a case of a 30-year-old woman in week 31 of her pregnancy who developed acute mitral regurgitation, secondary to bacterial endocarditis an...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-2007-994418

    authors: Hagay ZJ,Weissman A,Geva D,Snir E,Caspi A

    更新日期:1995-03-01 00:00:00

  • Hypophosphatemia is Prevalent among Preterm Infants Less than 1,500 Grams.

    abstract:OBJECTIVE:This article identifies the prevalence and associated factors of hypophosphatemia (HP) in very low birth weight (VLBW) infants in the first week of life. STUDY DESIGN:Prospective exploratory cohort study of 106 consecutive VLBW infants admitted to neonatal intensive care at Foothills Hospital, Calgary, Canad...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-0039-1677713

    authors: Al-Wassia H,Lyon AW,Rose SM,Sauve RS,Fenton TR

    更新日期:2019-11-01 00:00:00

  • The significance of a positive fetal fibronectin in the setting of a normal cervical length in twin pregnancies.

    abstract::To estimate the risk of preterm birth in asymptomatic women with twin pregnancies with a normal cervical length (CL) and a positive fetal fibronectin (fFN), we reviewed a retrospective cohort of twin pregnancies delivered in our practice from 2005 to 2010. Patients were screened from 22 to 32 weeks with CL and fFN at ...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-0031-1285827

    authors: Fox NS,Rebarber A,Roman AS,Klauser CK,Saltzman DH

    更新日期:2012-04-01 00:00:00

  • High incidence of cord entanglement during early pregnancy detected by three-dimensional sonography.

    abstract::We sought to determine the incidence of cord entanglement around any part of fetal body during early gestation using three-dimensional (3D) sonography. A prospective consecutive study was designed and 3D ultrasound was performed. Two hundred thirty-seven singleton pregnancies between 13 and 16 weeks were included. Cor...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-0028-1110090

    authors: Tepper R,Kidron D,Aviram R,Markovitch O,Hershkovitz R

    更新日期:2009-05-01 00:00:00

  • Transient hyperinsulinism in an asphyxiated newborn infant with hypoglycemia.

    abstract::We describe a case of transient hyperinsulinism in an asphyxiated newborn infant with hypoglycemia. Although hypoglycemia in birth asphyxiated infants is generally attributed to depletion of glycogen stores, we observed severe hyperinsulinism associated with the hypoglycemia. The hypoglycemia was refractory to high gl...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-2001-15504

    authors: Clark W,O'Donovan D

    更新日期:2001-06-01 00:00:00

  • Effect of vibratory acoustic stimulation on the duration of fetal heart rate monitoring tests.

    abstract::The ability of vibratory acoustic stimulation to shorten the duration of antepartum fetal heart rate monitoring was investigated by a randomized controlled trial. Vibratory acoustic stimulation did not shorten the overall duration of testing. This failure to improve the performance of antepartum monitoring appeared to...

    journal_title:American journal of perinatology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1055/s-2007-999489

    authors: Newnham JP,Burns SE,Roberman BD

    更新日期:1990-07-01 00:00:00

  • Umbilical cord serum interleukin-6, C-reactive protein, and myeloperoxidase concentrations at birth and association with neonatal morbidities and long-term neurodevelopmental outcomes.

    abstract:OBJECTIVE:The aim of the study is to determine if umbilical cord serum concentrations of interleukin-6 (IL-6), C-reactive protein (CRP), and myeloperoxidase (MPO), in pregnancies at risk for preterm birth (PTB), are associated with neonatal morbidities and/or altered neurodevelopmental outcomes in the children. STUDY ...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-0033-1359723

    authors: Sorokin Y,Romero R,Mele L,Iams JD,Peaceman AM,Leveno KJ,Harper M,Caritis SN,Mercer BM,Thorp JM,O'Sullivan MJ,Ramin SM,Carpenter MW,Rouse DJ,Sibai B

    更新日期:2014-09-01 00:00:00

  • Sonographic measurement of the fetal iliac bone: growth and relation to femur length in assessment of gestational age.

    abstract::Diagnostic ultrasonography has given us the opportunity to diagnose several congenital malformations in utero. Skeletal dysplasias is a heterogeneous group of disorders of the skeleton. Although disorders of bone growth are often diagnosed in utero, it is usually a general diagnosis because the exact syndrome cannot b...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-2007-994638

    authors: Jaffe R,Santolaya J,Warsof SL

    更新日期:1993-03-01 00:00:00

  • The risk for preterm labor in women receiving 17 alpha-hydroxyprogesterone caproate prophylaxis for preterm birth prevention.

    abstract::We sought to identify maternal or clinical characteristics of women likely to develop preterm labor (PTL) at <34 weeks' gestation while receiving 17 alpha-hydroxyprogesterone caproate (17P) prophylaxis. Current singleton gestations with prior preterm delivery enrolled for outpatient 17P administration at <27 weeks' ge...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-0029-1243306

    authors: Joy S,Rhea DJ,Istwan NB,Desch CN,Stanziano G

    更新日期:2010-04-01 00:00:00

  • Application of transcutaneous carbon dioxide tension monitoring with low electrode temperatures in premature infants in the early postnatal period.

    abstract:OBJECTIVE:The aim of this article is to evaluate the accuracy, precision, and safety of transcutaneous carbon dioxide tension (TcPCO2) monitoring at different electrode temperatures in preterm infants in the early postnatal period. STUDY DESIGN:A total of 26 neonates with a median birth weight of 974 g (432-1,694 g) a...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-0033-1352485

    authors: Hirata K,Nishihara M,Oshima Y,Hirano S,Kitajima H

    更新日期:2014-05-01 00:00:00

  • Risks of Preterm Premature Rupture of Membranes and Preterm Birth Post Fetoscopy Based on Location of Trocar Insertion Site.

    abstract:OBJECTIVE:The objective of this study was to assess whether the location of the trocar insertion site for laser treatment of twin-twin transfusion syndrome was associated with preterm-premature rupture of membranes (PPROM) and preterm birth (PTB). STUDY DESIGN:In this study trocar location was documented in the operat...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-0037-1620268

    authors: Chmait RH,Chon AH,Korst LM,Llanes A,Kontopoulos EV,Quintero RA

    更新日期:2018-07-01 00:00:00

  • Variables associated with successful vaginal birth after one cesarean section: a proposed vaginal birth after cesarean section score.

    abstract::The objective of this study was to define the variables associated with vaginal birth after cesarean section (VBAC) and to develop a scoring system for the prediction of successful VBAC. We searched our computerized database for parturients with a history of one low-transverse cesarean section (CS) who were delivered ...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-2004-835961

    authors: Gonen R,Tamir A,Degani S,Ohel G

    更新日期:2004-11-01 00:00:00

  • The value of the leukocyte esterase test in diagnosing intra-amniotic infection.

    abstract::This communication examines the diagnostic value of the leukocyte esterase activity (LEA) test in the detection of intra-amniotic infection. Amniotic fluid from 171 consecutive patients with premature rupture of membranes (n = 149) and preterm labor (n = 22) was obtained through amniocentesis. Gram stain, bacterial an...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-2007-999657

    authors: Romero R,Emamian M,Wan M,Yarkoni S,McCormack W,Mazor M,Hobbins JC

    更新日期:1988-01-01 00:00:00

  • Preterm delivery: correlations of fetal growth and placental pathology.

    abstract::The present study of 466 consecutive liveborn preterm singleton deliveries included 238 cases of spontaneous preterm labor and delivery, 175 cases with premature rupture of membranes, 13 cases of nonhypertensive abruption, 18 cases of preeclampsia, and 22 cases of placenta previa. Placental infarction, chronic villiti...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-2007-999318

    authors: Salafia CM,Vogel CA,Bantham KF,Vintzileos AM,Pezzullo J,Silberman L

    更新日期:1992-05-01 00:00:00

  • Obstetric outcomes of human immunodeficiency virus-1-serodiscordant couples following in vitro fertilization with intracytoplasmic sperm injection.

    abstract::The objective of this article is to report obstetric outcomes of human immunodeficiency virus-1 (HIV-1)-serodiscordant couples who underwent in vitro fertilization and embryo transfer (IVF-ET) with intracytoplasmic sperm injection (ICSI) at a tertiary care center. We reviewed the outcomes of seronegative women after I...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-2003-42694

    authors: Cleary-Goldman J,Peña JE,Thornton MH 2nd,Robinson JN,D'Alton ME,Sauer MV

    更新日期:2003-08-01 00:00:00

  • A Novel Partogram for Stages 1 and 2 of Labor Based on Fetal Head Station Measured by Ultrasound: A Prospective Multicenter Cohort Study.

    abstract:OBJECTIVE: This study was aimed to describe continuous labor curves, including second stage, based on fetal head station. STUDY DESIGN: We performed a prospective multicenter cohort study. The inclusion criteria were women with singleton uncomplicated cephalic term pregnancies in labor, who delivered vaginally. We use...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-0040-1702989

    authors: Haberman S,Atallah F,Nizard J,Buhule O,Albert P,Gonen R,Ville Y,Paltieli Y

    更新日期:2020-03-02 00:00:00

  • Nonimmune hydrops fetalis secondary to premature closure of the foramen ovale.

    abstract::Premature closure of the foramen ovale is a rare cardiac anomaly. Severe right-sided heart failure accounts for the hepatomegaly, ascites, pleural and pericardial effusions, and generalized edema of these hydropic fetuses. Premature closure of the foramen ovale should be a part of the differential diagnosis when unexp...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-2007-994616

    authors: Coulson CC,Kuller JA

    更新日期:1994-11-01 00:00:00

  • High-frequency jet ventilation improves gas exchange in extremely immature infants with evolving chronic lung disease.

    abstract::Extremely preterm infants often develop chronic lung disease (CLD) characterized by heterogeneous aeration; poorly supported, floppy airways; and air trapping. High-frequency jet ventilation (HFJV) with high end-expiratory pressure (optimal lung volume strategy [OLVS]) may improve airway patency, lead to better gas di...

    journal_title:American journal of perinatology

    pub_type: 临床试验,杂志文章

    doi:10.1055/s-2006-954821

    authors: Plavka R,Dokoupilová M,Pazderová L,Kopecký P,Sebron V,Zapadlo M,Keszler M

    更新日期:2006-11-01 00:00:00

  • Glycemic Control and Pregnancy Outcomes in Women with Type 2 Diabetes Treated with Oral Hypoglycemic Agents.

    abstract::Objective There is limited data regarding the use of oral hypoglycemic agents (OHAs) in pregnant women with type 2 diabetes mellitus (T2DM). Study Design This was a retrospective cohort study of women with T2DM who were treated with OHA or insulin from the first trimester onward. Bivariate and multivariate logistic re...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-0036-1597625

    authors: Feghali MN,Caritis SN,Catov JM,Scifres CM

    更新日期:2017-06-01 00:00:00

  • Neonatal Morbidities among Moderately Preterm Infants with and without Exposure to Antenatal Corticosteroids.

    abstract:OBJECTIVE:We aimed to compare the rates of "surfactant treated respiratory disease" and other neonatal morbidities among moderately preterm (MPT) infants exposed to no, partial, or a complete course of antenatal corticosteroids (ANS). STUDY DESIGN:This observational cohort study evaluated MPT infants (290/7-336/7 week...

    journal_title:American journal of perinatology

    pub_type: 杂志文章,多中心研究

    doi:10.1055/s-0038-1642059

    authors: Chawla S,Natarajan G,Chowdhury D,Das A,Walsh M,Bell EF,Laptook AR,Van Meurs K,D'Angio CT,Stoll BJ,DeMauro SB,Shankaran S

    更新日期:2018-10-01 00:00:00

  • Birth weight and gestational age standards based on regional perinatal network data: an analysis of risk factors.

    abstract::The most frequently used set of gestational age-birth weight curves in the United States is the Colorado (C) standard published in 1963. To investigate the usefulness of this standard in an urban population at sea level, we examined the birth weight vs gestational age data from 56,675 singleton liveborn infants born b...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-2007-999785

    authors: Raju TN,Winegar A,Seifert L,Miller S

    更新日期:1987-07-01 00:00:00

  • Gestational Weight Gain and Pregnancy Outcomes among Nulliparous Women.

    abstract:OBJECTIVE: To determine the association between total gestational weight gain and perinatal outcomes. STUDY DESIGN: Data from the Nulliparous Pregnancy Outcomes Study: Monitoring Mothers-To-Be (NuMoM2b) study were used. Total gestational weight gain was categorized as inadequate, adequate, or excessive based on the 20...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-0039-1696640

    authors: Dude AM,Grobman W,Haas D,Mercer BM,Parry S,Silver RM,Wapner R,Wing D,Saade G,Reddy U,Iams J,Kominiarek MA

    更新日期:2021-01-01 00:00:00