Abstract:
:Objective There is limited data regarding the use of oral hypoglycemic agents (OHAs) in pregnant women with type 2 diabetes mellitus (T2DM). Study Design This was a retrospective cohort study of women with T2DM who were treated with OHA or insulin from the first trimester onward. Bivariate and multivariate logistic regression analyses were used to compare pregnancy outcomes in women treated with OHA to those treated with insulin. Results One-third (67/198) of women were treated with OHA. Women treated with OHA had a shorter disease duration (4.4 vs. 6.8 years; p = 0.001), were more likely to have a normal prepregnancy body mass index, and had less gestational weight gain (GWG; 22.4 vs. 30.4 lbs; p = 0.005). A lower GWG was noted in obese women treated with OHA (19.9 ± 18.6 vs. 28.3 ± 17.7 pounds; p = 0.008). First-trimester hemoglobin A1c values were lower with OHAs, but second- and third-trimester values were similar. Among women who started pregnancy using OHA, 37/67 (55.2%) remained on OHA at delivery. Pregnancy outcomes did not differ between women who received OHA and those treated with insulin. Conclusion OHA treatment is more likely in women with T2DM who begin pregnancy with less severe disease, and use of OHA may be associated with decreased GWG.
journal_name
Am J Perinatoljournal_title
American journal of perinatologyauthors
Feghali MN,Caritis SN,Catov JM,Scifres CMdoi
10.1055/s-0036-1597625subject
Has Abstractpub_date
2017-06-01 00:00:00pages
697-704issue
7eissn
0735-1631issn
1098-8785journal_volume
34pub_type
杂志文章abstract::Rh disease has largely disappeared as a result of prophylaxis with anti-D. However, the cases that remain are more complicated with a combination of novel challenges with regard to in utero management with transfusion and its effects on the course of the neonate, both early and late. Thrombocytopenia in the neonate ca...
journal_title:American journal of perinatology
pub_type: 杂志文章,评审
doi:10.1055/s-2003-45392
更新日期:2003-11-01 00:00:00
abstract::A case of massive hydramnios involving a twin-twin transfusion syndrome is presented with death of the larger twin and the development of hydrops fetalis in the surviving smaller twin. The amniotic fluid volume of the surviving twin became normal and the hydrops fetalis resolved spontaneously in utero. Concomitant wit...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-999457
更新日期:1990-04-01 00:00:00
abstract::The accuracy of eight ultrasonic fetal weight formulas were analyzed in 1099 fetuses who underwent real-time ultrasound examination within 72 hours prior to delivery. Shepard's formula was most consistently found to give the lowest systematic and random errors throughout all weight categories, though Deter's formula h...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-999944
更新日期:1985-07-01 00:00:00
abstract::The combination of multicystic kidney and crossed ectopia is very rare. In most of the affected children, diagnosis has been made postnatally by ultrasonographic examination to evaluate a palpated abdominal mass. We describe the third male newborn reported in the literature with a prenatally diagnosed crossed ectopic ...
journal_title:American journal of perinatology
pub_type: 杂志文章,评审
doi:10.1055/s-2007-994073
更新日期:1998-08-01 00:00:00
abstract::Persistent fetal bradycardia is rarely encountered during pregnancy. When it is associated with a complete atrio-ventricular (A-V) block, it may prove dangerous to the fetus or newborn. The prenatal diagnosis is vital because it necessitates close follow-up during pregnancy to detect fetal compromise and proper prepar...
journal_title:American journal of perinatology
pub_type: 杂志文章,评审
doi:10.1055/s-2007-994152
更新日期:1997-07-01 00:00:00
abstract::A hospital-based case-controlled study was undertaken to determine maternal and neonatal characteristics associated with fractured clavicle. A total of 11,604 consecutive vaginal deliveries of liveborn infants in vertex presentation at the Mount Sinai Hospital from 1988 to 1990 were reviewed. Maternal and neonatal cha...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-994546
更新日期:1994-09-01 00:00:00
abstract::This is the first reported case in which a Logothetopulos pack was utilized to achieve pelvic hemostasis in a patient requiring a cesarean hysterectomy for placenta accreta with postpartum hemorrhage. The Logothetopulos pack is an easily constructed gauze tamponade method that proved to be life-saving in this case. ...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-999514
更新日期:1990-10-01 00:00:00
abstract::The effect of active management on latent phase labor was assessed in 197 consecutive nulliparous women. Active management resulted in a significant shortening of the latent phase but had no effect on active phase labor. Patients undergoing induction of labor had latent phases that were almost identical to the accepte...
journal_title:American journal of perinatology
pub_type: 临床试验,杂志文章
doi:10.1055/s-2007-999524
更新日期:1990-10-01 00:00:00
abstract::To minimize the selection bias inherent in reporting results gathered only in neonatal intensive care units, this study presents survival and respiratory course data on all 299 infants of birthweight 501 to 1500 gm liveborn to residents of the North Central Illinois Perinatal Region in 1985-1986. The survival rate was...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-999632
更新日期:1989-10-01 00:00:00
abstract::Previous work has shown that fetal hydrographic magnetic resonance imaging (MRI) provided additional information complementary to T2-weighted single-shot fast spin echo (ssFSE) images. The objective of this study was to determine if hydrographic MRI provides better conspicuity of fetal eye structures compared with ssF...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0031-1295636
更新日期:2012-04-01 00:00:00
abstract::Objective We aimed to evaluate which patient-level factors influence mode of delivery among candidates for operative vaginal delivery. Study Design Cross-sectional study of candidates for operative vaginal delivery from 18 hospitals over 8 years. Probabilities of mode of delivery were estimated using hierarchical logi...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0037-1601441
更新日期:2017-08-01 00:00:00
abstract::The presence of the maternal warm antibody in pregnancy should not be ignored. As there is risk of both maternal and fetal anemia, both patients need to be followed for the development of such. Serial complete blood counts in the mother and treatment if significant fetal anemia develops should be considered. Serial am...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-994196
更新日期:1996-01-01 00:00:00
abstract:OBJECTIVE:This study assessed the impact of a nurse simulation training program on perception of kangaroo mother care (KMC) value and transfer skill competency. STUDY DESIGN:An 8-item Likert scale skill survey tool and a 24-item Likert developmental care survey tool were used in a prospective cohort study to analyze p...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0034-1371359
更新日期:2014-11-01 00:00:00
abstract::Osteomyelitis is rarely complicated by an infected cephalohematoma. We report a case of an infected cephalohematoma associated with Escherichia coli sepsis and osteomyelitis of the skull. This 37-day-old boy had E. coli sepsis, which had a poor response to antibiotic treatment. An infected cephalohematoma was found wh...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-1999-6803
更新日期:1999-01-01 00:00:00
abstract::Surfactants have been routinely used since 1990 for the treatment of respiratory distress syndrome (RDS). The use of surfactant has coincided with a decrease in mortality in infants due to RDS. This review focuses on clinical aspects of surfactant use. New information, particularly effects of ventilatory styles on sur...
journal_title:American journal of perinatology
pub_type: 杂志文章,评审
doi:10.1055/s-2000-13445
更新日期:2000-01-01 00:00:00
abstract:OBJECTIVE:To evaluate to what extent indicators of placenta insufficiency are associated with low concentrations of insulin-like growth factor 1 (IGF-1) and IGF-1-binding protein-1 (IGFBP-1) in neonatal blood, and to what extent the concentrations of these growth factors are associated with concentrations of proteins w...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0038-1677472
更新日期:2019-12-01 00:00:00
abstract:OBJECTIVE: This study aimed to assess whether cord blood carboxyhemoglobin (COHb) levels in jaundiced term neonates with and without a positive direct Coombs test (DCT) and in healthy controls could be used as a predictor of severe hyperbilirubinemia. The percentage of cord blood COHb should be higher among neonates wi...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0040-1722328
更新日期:2021-01-04 00:00:00
abstract::We evaluated the methodological quality of economic evaluation studies in the field of obstetrics and gynecology published in the last decade. A MEDLINE search was performed to find economic evaluation studies in obstetrics and gynecology from the years 1997 through 2009. We included full economic evaluation studies c...
journal_title:American journal of perinatology
pub_type: 杂志文章,评审
doi:10.1055/s-0032-1323591
更新日期:2013-04-01 00:00:00
abstract::A 38-year-old para 2 presented with the gradual onset of nausea vomiting and increasing left lower quadrant pain, at 33 weeks' gestation. She was known to have uterine leiomyomas, with ultrasonography depicting an 8-cm intramural fundal leiomyoma. In addition a left lateral nondiscrete 10 x 8-cm mass was depicted at t...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2001-13639
更新日期:2001-01-01 00:00:00
abstract:OBJECTIVE:The Misgav-Ladach technique is recommended worldwide to perform cesarean sections but there is no consensus about the appropriate technique to use in patients with previous cesarean sections. This study evaluated the feasibility of the Misgav-Ladach technique in patients with previous cesarean sections. STUD...
journal_title:American journal of perinatology
pub_type: 临床试验,杂志文章
doi:10.1055/s-0032-1323580
更新日期:2013-03-01 00:00:00
abstract:OBJECTIVE:To determine the effect of increasing maternal obesity, including superobesity (body mass index [BMI] ≥ 50 kg/m2), on perinatal outcomes in women with diabetes. STUDY DESIGN:Retrospective cohort study of birth records for all live-born nonanomalous singleton infants ≥ 37 weeks' gestation born to Missouri res...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0033-1347363
更新日期:2014-03-01 00:00:00
abstract::Although mother's milk is the optimal nutrition for preterm infants, the amount of protein, calcium, and phosphorus become inadequate for the growth of preterm infants, such that fortification is recommended when enteral feeding is established. Recently, intestinal obstruction due to calcium soap formation has been re...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0031-1295659
更新日期:2012-04-01 00:00:00
abstract:OBJECTIVE: Potentially avoidable maternity complications (PAMCs) have been validated as an indicator of access to quality prenatal care. African-American mothers have exhibited a higher incidence of PAMCs, which has been attributed to unequal health coverage. The objective of this study was to assess if racial disparit...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0040-1701195
更新日期:2020-01-27 00:00:00
abstract::Our objective was to describe the change in the level of troponin I in patients who undergo a vaginal or cesarean delivery. We obtained troponin I levels on admission and 1 hour after delivery in women undergoing vaginal and cesarean deliveries. Exclusion criteria included <37 weeks' gestation, a history of cardiac di...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2004-820507
更新日期:2004-01-01 00:00:00
abstract::Five cases of sirenomelia presented with rare manifestations are discussed. Three neonates were born alive and died within 2 to 12 hours after birth. One case was the offspring of a triple in vitro fertilization pregnancy with history of early intrauterine death of one of the triplets. The main features included fusio...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2004-835314
更新日期:2004-10-01 00:00:00
abstract::Serial ultrasound measurements of the fetus under investigation is an important indicator of fetal growth, and thus fetal health. To assess how reliable those measurements are, a videotape was made, and, utilizing an ultrasound machine that allowed the placement of callipers on the videotape, the dispersion of the mea...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-999271
更新日期:1992-09-01 00:00:00
abstract::The primary objective of this study was to determine whether having the sickle cell trait is independently associated with preeclampsia. We performed a retrospective cohort study of 1998 pregnant patients who either did or did not have the sickle cell trait. All patients were screened for the sickle trait using the "S...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2003-37953
更新日期:2003-01-01 00:00:00
abstract:OBJECTIVE:This study aimed to evaluate if maternal serum hormones along the maternal-fetal hypothalamic-pituitary-adrenal (HPA) axis, when drawn prior to labor induction, differed between women who delivered vaginally and those who underwent cesarean. STUDY DESIGN:This was a prospective observational study at a single...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0040-1708801
更新日期:2020-10-01 00:00:00
abstract:OBJECTIVES:This article prospectively examines the use of ultrasound for antenatal detection of abnormal placental cord insertion (PCI) and compares the antenatal classification with delivered placental classification. STUDY DESIGN:This prospective cohort study examined 277 singleton pregnancies in a tertiary center. ...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0039-3400309
更新日期:2020-01-01 00:00:00
abstract::Intra-oral enteric duplication cysts are rare. We recently treated two infants with prenatally diagnosed large sublingual enteric duplication cysts. Antenatal aspiration of the cyst was attempted in one infant without success. Because of the potential for airway obstruction and respiratory distress at delivery, prepar...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-994119
更新日期:1997-03-01 00:00:00