Rare manifestations of sirenomelia syndrome: a report of five cases.

Abstract:

:Five cases of sirenomelia presented with rare manifestations are discussed. Three neonates were born alive and died within 2 to 12 hours after birth. One case was the offspring of a triple in vitro fertilization pregnancy with history of early intrauterine death of one of the triplets. The main features included fusion of lower extremities (five of five), renal agenesis (three of five), polycystic renal dysplasia (two of five), anal atresia with large bowel hypoplasia (three of five), pulmonary hypoplasia (four of five), and single umbilical artery (five of five). Other features that have only rarely been associated with sirenomelia included concurrence of congenital heart disease and neuroblastoma, gallbladder agenesis, and upper extremity defects.

journal_name

Am J Perinatol

authors

Drossou-Agakidou V,Xatzisevastou-Loukidou C,Soubasi V,Kostopoulou E,Laporda A,Pantzaki A,Agelidou S,Kremenopoulos G

doi

10.1055/s-2004-835314

subject

Has Abstract

pub_date

2004-10-01 00:00:00

pages

395-401

issue

7

eissn

0735-1631

issn

1098-8785

journal_volume

21

pub_type

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