Abstract:
OBJECTIVE:The aim of this study is to describe the changes in term fetal heart tracings after magnesium exposure. MATERIALS AND METHODS:This was a retrospective cohort study of consecutive women delivering at a gestational age of ≥ 37 weeks with severe preeclampsia, receiving magnesium for seizure prophylaxis. Overall 90 minutes of electronic fetal monitoring (30 before magnesium, 30 during magnesium bolus, and 30 during steady state infusion) was prospectively interpreted by formally trained and blinded research nurses using American Congress of Obstetricians and Gynecologists guidelines. Multivariable analyses were performed using generalized estimating equations, comparing preexposure patterns to bolus, and steady state. RESULTS:Out of the 238 women evaluated, an average decrease of 2.4 beats per minute (p = 0.02) was found after magnesium bolus. This persisted into the steady state (p < 0.01). Minimal/absent variability increased during bolus infusion (odds ratio [OR] 2.40, 95% confidence interval [CI] 1.10-5.62) but corrected by steady state (OR 1.44, 95% CI 0.76-2.80). There were no significant changes in the fetal heart rate (FHR) baseline < 120, tachycardia, or presence of accelerations or decelerations. CONCLUSION:Exposure to magnesium is associated with a transient decrease in variability and a clinically insignificant decrease in FHR baseline without an increased incidence in bradycardia or category change.
journal_name
Am J Perinatoljournal_title
American journal of perinatologyauthors
Stewart AM,Macones GA,Odibo AO,Colvin R,Cahill AGdoi
10.1055/s-0033-1363499subject
Has Abstractpub_date
2014-11-01 00:00:00pages
869-74issue
10eissn
0735-1631issn
1098-8785journal_volume
31pub_type
杂志文章abstract::We sought to identify maternal or clinical characteristics of women likely to develop preterm labor (PTL) at <34 weeks' gestation while receiving 17 alpha-hydroxyprogesterone caproate (17P) prophylaxis. Current singleton gestations with prior preterm delivery enrolled for outpatient 17P administration at <27 weeks' ge...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0029-1243306
更新日期:2010-04-01 00:00:00
abstract:OBJECTIVE:This study was aimed to evaluate the prevalence of sonographic markers for placenta accreta spectrum (PAS) in pregnancies at low-risk for PAS. STUDY DESIGN:Pregnant women at low-risk for PAS presenting for routine second trimester ultrasound who enrolled in the study were evaluated prospectively for sonograp...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0038-1676488
更新日期:2019-07-01 00:00:00
abstract:INTRODUCTION:Many tertiary neonatal units employ a restricted visiting policy. Webcams have previously been implemented in the neonatal unit setting in several countries. OBJECTIVES:This study aims to determine the views from parents, physicians, and nursing staff before implementation of a webcam system. METHODS:A q...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0034-1376388
更新日期:2015-02-01 00:00:00
abstract::The concentration of myometrial and decidual oxytocin receptors increases dramatically in normal women in late pregnancy, causing enhanced uterine sensitivity to physiologic levels of oxytocin. Similar increase in myometrial oxytocin receptors has been found in women in preterm labor, indicating a role for oxytocin al...
journal_title:American journal of perinatology
pub_type: 临床试验,杂志文章
doi:10.1055/s-2007-999575
更新日期:1989-04-01 00:00:00
abstract::Objective To compare maternal birth complications early versus late in the academic year and to evaluate the impact of resident work hour limitation on the "July effect." Study Design We conducted a retrospective, population-based cohort study of 628,414 singleton births in Washington State from 1987 to 2012 measuring...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0037-1598244
更新日期:2017-07-01 00:00:00
abstract:OBJECTIVE: The study aims to assess the impact on neurodevelopmental outcomes of a prolonged hemodynamically significant patent ductus arteriosus (PDA) after a conservative treatment. STUDY DESIGN: This involves the study of two cohorts of preterm infants 23 to 29 weeks gestation, before (n = 29) and after (n = 54) a ...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0039-1697674
更新日期:2019-10-10 00:00:00
abstract::We sought to describe a case series and literature review of uterine rupture in the absence of a previous cesarean delivery. In addition to four cases in our institution, a search of the literature from 1994 to 2008 identified cases of uterine rupture unrelated to a prior cesarean. Uterine rupture in the absence of a ...
journal_title:American journal of perinatology
pub_type: 杂志文章,评审
doi:10.1055/s-0029-1223287
更新日期:2009-11-01 00:00:00
abstract:BACKGROUND:Postnatal assessment of disease severity is critical for analysis of mortality rates and development of future interventions in congenital diaphragmatic hernia (CDH). OBJECTIVE:The objective of this study was to stratify the risk of mortality based on arterial Paco 2. METHODS:Retrospective analysis of infa...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0034-1368088
更新日期:2014-11-01 00:00:00
abstract::We have examined the safety and efficacy of an early postpartum discharge program in 289 patients who were identified prior to delivery and counseled and educated for discharge 12 to 36 hours after delivery. A total of 55% of the study patients were able to be discharged early. There were 4.3% significant maternal pro...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-994768
更新日期:1993-09-01 00:00:00
abstract:OBJECTIVE:To determine if increasing predicted risk of cesarean was associated with longer labor length and increased morbidity among women undergoing induction with an unfavorable cervix. STUDY DESIGN:Using a publically available database, we evaluated whether a previously validated prediction model for cesarean deli...
journal_title:American journal of perinatology
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doi:10.1055/s-0038-1675625
更新日期:2019-05-01 00:00:00
abstract::Primary genital herpes simplex virus (HSV) infection in pregnancy is associated with an increased risk of vertical transmission to the fetus, especially with rupture of membranes. Two cases of primary herpes and two cases of recurrent herpes in pregnancy with preterm premature rupture of membranes and expectant manage...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2002-33090
更新日期:2002-07-01 00:00:00
abstract::A 27-year-old primigravida women was referred for ultrasound studies at 32 weeks' gestation because of the suspicion of fetal ventriculomegaly. Sonographic examination of the fetal brain found a marked shift of the midline, with enlarged left hemisphere and ipsilateral occipital horn, and abnormal convolutions. A 3500...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-999330
更新日期:1991-01-01 00:00:00
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journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0039-1693988
更新日期:2020-12-01 00:00:00
abstract::The effect of active management on latent phase labor was assessed in 197 consecutive nulliparous women. Active management resulted in a significant shortening of the latent phase but had no effect on active phase labor. Patients undergoing induction of labor had latent phases that were almost identical to the accepte...
journal_title:American journal of perinatology
pub_type: 临床试验,杂志文章
doi:10.1055/s-2007-999524
更新日期:1990-10-01 00:00:00
abstract::We investigated body mass index (BMI) and weight gain among pregnant women (ages 14 to 25) and assessed the relationship of BMI and weight gain on birth outcomes. We performed a secondary analysis of 841 women enrolled in a randomized controlled trial receiving prenatal care in two university-affiliated clinics. Almos...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0028-1110088
更新日期:2009-05-01 00:00:00
abstract::Serial ultrasound measurements of the fetus under investigation is an important indicator of fetal growth, and thus fetal health. To assess how reliable those measurements are, a videotape was made, and, utilizing an ultrasound machine that allowed the placement of callipers on the videotape, the dispersion of the mea...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-999271
更新日期:1992-09-01 00:00:00
abstract::One hundred twenty-one patients underwent an ultrasound examination within 48 hours of delivery to assess prospectively the reliability of the diagnosis of intrauterine growth retardation. Sonographic parameters examined included the abdominal circumference, sonographic estimate of fetal weight, the head to abdominal ...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-999622
更新日期:1989-10-01 00:00:00
abstract::Type 1 cystic sacrococcygeal teratomas, usually associated with good outcome following neonatal resection, must be differentiated at the time of prenatal diagnosis from sonographically similar meningomyeloceles, which carry a grave prognosis. We present an unusual case in which color Doppler imaging assisted correct m...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-994089
更新日期:1997-01-01 00:00:00
abstract::Amniocentesis to guide the management of preterm pregnancies complicated by premature rupture of the membranes (PROM) has been adopted at several centers. The purpose of this study was to evaluate this practice prospectively among comparable groups of patients, which has not previously been reported. Forty-seven patie...
journal_title:American journal of perinatology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1055/s-2007-1000031
更新日期:1984-07-01 00:00:00
abstract::Carbamoyl phosphate synthetase deficiency is a type of an inborn error of metabolism with a poor prognosis. Carbamoyl phosphate synthetase is a liver-specific enzyme, and its deficiency can only be diagnosed by enzyme assay using liver biopsy specimens. A pregnant woman at risk for carbamoyl phosphate synthetase defic...
journal_title:American journal of perinatology
pub_type: 杂志文章,评审
doi:10.1055/s-2007-994579
更新日期:1994-03-01 00:00:00
abstract::We studied Stem cell factor (SCF) levels in 15 mother-newborn pairs, 15 healthy adult controls, and 16 newborn with bacterial sepsis. SCF levels were also determined in six newborns with sepsis before and after completion of treatment. SCF levels (pg/mL) were found to be 2141 +/- 529 in cord blood, 1385 +/- 314 in mot...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-993970
更新日期:1998-07-01 00:00:00
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journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2005-918889
更新日期:2006-01-01 00:00:00
abstract:OBJECTIVE:This study aims to identify risk factors for cesarean delivery (CD) surgical site infection (SSI). study design: Retrospective analysis of 2,739 CDs performed at the University of Pittsburgh in 2011. CD SSIs were defined using National Healthcare Safety Network (NHSN) criteria. Chi-square test and t-test were...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0035-1563548
更新日期:2016-01-01 00:00:00
abstract::The aim of the study was to investigate the effect of individual room care in the neonatal intensive care unit (NICU) on the factors that influence mother-preterm infant interaction. Mothers in group I had hospitalization with their preterm infants in an individual room in the NICU. Mothers in group II were not hospit...
journal_title:American journal of perinatology
pub_type: 杂志文章,多中心研究
doi:10.1055/s-0028-1095186
更新日期:2009-02-01 00:00:00
abstract::Although various authors recommend screening for hypoglycemia in large for gestational age (LGA) and small for gestational age (SGA) newborns, the frequency of hypoglycemia in these infants, using a recent definition of hypoglycemia, and the proper duration of screening are not documented. We determined chromogen test...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-994649
更新日期:1993-03-01 00:00:00
abstract::The purpose of this study was to examine the maternal risk factors associated with early onset Group B streptococcus (GBS) sepsis and determine the potential impact of intrapartum chemoprophylaxis using these risk factors. Using a computerized perinatal database, 26,525 deliveries over a five-year period (1989 to 1994...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-994433
更新日期:1996-11-01 00:00:00
abstract:OBJECTIVE: This study aimed to examine the effects of interpregnancy weight change on pregnancy outcomes, including recurrent preeclampsia, preterm birth, small-for-gestational age (SGA), large-for-gestational age (LGA), and cesarean delivery, among women with a history of preeclampsia. We also evaluated whether these ...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0040-1713000
更新日期:2020-06-10 00:00:00
abstract::Progress in neonatal care has decrease morbidity and mortality due to neonatal sepsis (NS). Although diagnosis of sepsis continues to rely on blood culture, this method is too slow and limited by false-negative results. There are numerous sepsis biomarkers that have been evaluated for the early diagnosis of NS, but, t...
journal_title:American journal of perinatology
pub_type: 杂志文章,评审
doi:10.1055/s-0038-1639361
更新日期:2018-05-01 00:00:00
abstract::The primary objective of this study was to determine whether having the sickle cell trait is independently associated with preeclampsia. We performed a retrospective cohort study of 1998 pregnant patients who either did or did not have the sickle cell trait. All patients were screened for the sickle trait using the "S...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2003-37953
更新日期:2003-01-01 00:00:00
abstract:AIM:The main purpose of this article is to assess trends in cytomegalovirus (CMV) infection reported among infants in California neonatal intensive care units (NICUs) during 2005 to 2016. STUDY DESIGN:The California Perinatal Quality Care Collaborative collects data on all very low birth weight (VLBW, birth weight ≤ 1...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0039-1683958
更新日期:2020-01-01 00:00:00