Abstract:
:The objective of this article is to report obstetric outcomes of human immunodeficiency virus-1 (HIV-1)-serodiscordant couples who underwent in vitro fertilization and embryo transfer (IVF-ET) with intracytoplasmic sperm injection (ICSI) at a tertiary care center. We reviewed the outcomes of seronegative women after IVF-ET with ICSI from January 1, 1997 to June 1, 2002. Serodiscordant couples (n = 25) successfully conceived 27 pregnancies delivering 40 neonates (16 singletons, 9 twins, and 2 triplets). The mean gestational age at delivery was 37 0/7 weeks +/- 3 6/7 weeks (range 26 0/7 to 41 2/7 weeks). The mean birth weight was 2646 g +/- 952 g (range 678 to 4396 g). The cesarean section rate was 70%. Preterm delivery (<37 weeks) occurred in 7 pregnancies, and low birth weight (<2500 g) was observed in 8 pregnancies. There were no HIV-1 seroconversions detected at delivery. One hundred percent of the mothers and offspring were beyond 3 months postpartum and remained seronegative. IVF-ET with ICSI seems safe and effective for serodiscordant couples. Obstetric outcomes are favorable, and HIV-1 infection risk is limited.
journal_name
Am J Perinatoljournal_title
American journal of perinatologyauthors
Cleary-Goldman J,Peña JE,Thornton MH 2nd,Robinson JN,D'Alton ME,Sauer MVdoi
10.1055/s-2003-42694subject
Has Abstractpub_date
2003-08-01 00:00:00pages
305-11issue
6eissn
0735-1631issn
1098-8785journal_volume
20pub_type
杂志文章abstract::Gestational diabetes mellitus (GDM) has increased dramatically in the past 20 years together with the obesity epidemic. Mirroring the increase in incidence of GDM is increasing use of endocrine disrupting chemicals (EDCs). EDCs are structurally similar to endogenous hormones and interfere with synthesis, secretion, ac...
journal_title:American journal of perinatology
pub_type: 杂志文章,评审
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更新日期:2016-11-01 00:00:00
abstract::I developed a single equation that simulated previously published growth charts for very low-birth-weight infants, using birth weight as the only variable. The intent of this study was to validate the equation using infants admitted to our neonatal intensive care unit (NICU) and to determine if this equation could be ...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-993914
更新日期:1998-02-01 00:00:00
abstract:OBJECTIVE:To evaluate the interobserver reliability of fetal heart rate (FHR) pattern definition and interpretation assessed by physicians at various levels of training using standard Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) definitions and standard principles of interpret...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0032-1326991
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pub_type: 杂志文章
doi:10.1055/s-0030-1253556
更新日期:2010-10-01 00:00:00
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journal_title:American journal of perinatology
pub_type: 杂志文章,多中心研究
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更新日期:2008-01-01 00:00:00
abstract::The antioxidant enzyme paraoxonase 1 is a marker of oxidative stress and has been implicated in the pathogenesis of preeclampsia. Our objective was to determine if an association exists between low paraoxonase 1 activity at midgestation and the development of preeclampsia. We conducted a case-control study of 50 women...
journal_title:American journal of perinatology
pub_type: 杂志文章
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journal_title:American journal of perinatology
pub_type: 临床试验,杂志文章
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更新日期:1995-07-01 00:00:00
abstract:OBJECTIVE:The Apgar score has been shown to have utility in predicting mortality in the extremely preterm infant in delivery hospital populations, where most mortality occurs within 12 hours of birth. We tested the hypothesis that the 5 minute Apgar score would remain associated with mortality in extremely preterm infa...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0035-1554803
更新日期:2015-11-01 00:00:00
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journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-993970
更新日期:1998-07-01 00:00:00
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journal_title:American journal of perinatology
pub_type: 杂志文章
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更新日期:2019-10-01 00:00:00
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journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0038-1676491
更新日期:2019-09-01 00:00:00
abstract::Limited research in young adults and immature animals suggests a detrimental effect of tobacco on bone during growth. We aimed to determine the adverse effects of maternal nicotine exposure during pregnancy and lactation on neonatal rat bone development, and to determine a protective effect of ascorbic acid. Gravid ra...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2006-951287
更新日期:2006-10-01 00:00:00
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journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0040-1722328
更新日期:2021-01-04 00:00:00
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journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-994524
更新日期:1994-01-01 00:00:00
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journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0038-1675219
更新日期:2019-06-01 00:00:00
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journal_title:American journal of perinatology
pub_type: 杂志文章,评审
doi:10.1055/s-2007-994365
更新日期:1996-05-01 00:00:00
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journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-981433
更新日期:2007-05-01 00:00:00
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journal_title:American journal of perinatology
pub_type: 杂志文章,评审
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更新日期:2009-11-01 00:00:00
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journal_title:American journal of perinatology
pub_type: 杂志文章
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journal_title:American journal of perinatology
pub_type: 杂志文章,评审
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更新日期:1998-08-01 00:00:00
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journal_title:American journal of perinatology
pub_type: 杂志文章
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更新日期:2019-01-01 00:00:00
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journal_title:American journal of perinatology
pub_type: 杂志文章
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更新日期:2020-06-28 00:00:00
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journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-999457
更新日期:1990-04-01 00:00:00
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journal_title:American journal of perinatology
pub_type: 杂志文章
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更新日期:1997-11-01 00:00:00
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journal_title:American journal of perinatology
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1990-07-01 00:00:00
abstract::A recent report has noted an association between Helicobacter pylori and hyperemesis gravidarum. We present two cases in which first-trimester patients with severe hyperemesis gravidarum requiring intravenous fluid replacement were placed on oral erythromycin therapy for other nonrelated conditions. Surprisingly, mark...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-994055
更新日期:1998-01-01 00:00:00
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journal_title:American journal of perinatology
pub_type: 杂志文章
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更新日期:2021-01-01 00:00:00
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journal_title:American journal of perinatology
pub_type: 杂志文章
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更新日期:2021-01-17 00:00:00
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journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-994724
更新日期:1993-05-01 00:00:00
abstract::We investigated body mass index (BMI) and weight gain among pregnant women (ages 14 to 25) and assessed the relationship of BMI and weight gain on birth outcomes. We performed a secondary analysis of 841 women enrolled in a randomized controlled trial receiving prenatal care in two university-affiliated clinics. Almos...
journal_title:American journal of perinatology
pub_type: 杂志文章
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更新日期:2009-05-01 00:00:00