Abstract:
OBJECTIVE: It is well established that women with a previous vaginal delivery have higher success rates in relation to vaginal birth after cesarean than those without. The aim of this study was to examine the effect of past mode of delivery on contractile parameters of human myometrium in vitro. STUDY DESIGN: Myometrial strips were excised from 64 women at cesarean delivery (CD) and recordings of spontaneous contractile activity analyzed and compared across three clinical groups: (1) women with no previous delivery (Group 1); (2) women with CD only (Group 2); and (3) women with a history of vaginal delivery and CD (Group 3). RESULTS: Myometrial samples from women in Group 3, women who had a previous vaginal delivery, had a significantly greater maximum amplitude of contractions (p < 0.05), a greater force (mean contractile force) of contractions (p < 0.01), and a faster rate of rise (p < 0.01) and relaxation of contractions (p < 0.05) than those in Groups 1 and 2. CONCLUSION: Many of the functional parameters of human uterine contractions are altered, or enhanced, in the women who have had a previous vaginal delivery, when compared with those without. This may partly explain the clinical differences observed in labor.
journal_name
Am J Perinatoljournal_title
American journal of perinatologyauthors
Ryan GA,Nicholson SM,Crankshaw DJ,Morrison JJdoi
10.1055/s-0039-1694980subject
Has Abstractpub_date
2021-01-01 00:00:00pages
126-130issue
2eissn
0735-1631issn
1098-8785journal_volume
38pub_type
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pub_type: 杂志文章,评审
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abstract:: ...
journal_title:American journal of perinatology
pub_type: 杂志文章,已发布勘误
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pub_type: 杂志文章
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pub_type: 杂志文章
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