Abstract：
:We studied the relationships between fetal hemoglobin concentration, acid base status, and lactate concentration in umbilical venous and fetal heart blood in 157 fetuses affected by blood group incompatibility who had been exposed for 214 fetal blood sampling procedures (cordocentesis in 153 and intracardiac puncture in 61 cases). All blood samplings were obtained before fetal blood transfusions were administered. The results indicate that the human fetus can maintain a normal acid-base status until a 50% reduction of the hemoglobin concentration. A further reduction of hemoglobulin is associated with an accumulation of lactate both in umbilical venous and fetal heart blood. The partial oxygen tension and the oxygen saturation in umbilical venous blood remained virtually unchanged with decreasing hemoglobin concentration (r = -0.11, P = 0.21; r = 0.09, P = 0.31, respectively), whereas these parameters decreased significantly (r = 0.33, P = 0.02; r = 34, P = 0.02) in blood obtained from the fetal heart. The partial carbon dioxide tension of umbilical vein blood decreases significantly with a reduced hemoglobin concentration (r = 0.25 P = 0.008). We speculate that these alterations in acid-base status in umbilical vein and fetal heart blood reflect a circulatory transition from a high to a low cardiac output as the hemoglobin concentration decreases.
journal_name
Am J Perinatoljournal_title
American journal of perinatologyauthors
Westgren M,Lingman G,Stangenberg Mdoi
10.1055/s-2007-994524subject
Has Abstractpub_date
1994-01-01 00:00:00pages
9-13issue
1eissn
0735-1631issn
1098-8785journal_volume
11pub_type
杂志文章abstract：:The effect of active management on latent phase labor was assessed in 197 consecutive nulliparous women. Active management resulted in a significant shortening of the latent phase but had no effect on active phase labor. Patients undergoing induction of labor had latent phases that were almost identical to the accepte...
journal_title：American journal of perinatology
pub_type： 临床试验,杂志文章
doi：10.1055/s-2007-999524
更新日期：1990-10-01 00:00:00
abstract：OBJECTIVE:The objective of this study was to evaluate the effectiveness of vaginal progesterone in reducing adverse neonatal outcome due to preterm birth (PTB) in low-risk pregnant women with a short cervical length (CL). STUDY DESIGN:Women with a singleton pregnancy without a history of PTB underwent CL measurement a...
journal_title：American journal of perinatology
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1055/s-0035-1547327
更新日期：2015-08-01 00:00:00
abstract：:First-trimester prenatal diagnosis was offered to 104 twin pregnancies mainly for advanced maternal age and cytogenetic evaluation of a new fertilization technique. Chorionic villus sampling (CVS) was performed transcervically (35%), transabdominally (23%), or by combination of these two techniques (42%). Although no ...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-994380
更新日期：1996-10-01 00:00:00
abstract：:The objective of this study was to evaluate the diagnostic accuracy of different single ultrasonographic parameters in predicting intrauterine growth-restricted (IUGR) babies as defined by Ponderal index at birth. Study sample composed of two sets of data from Iran and Australia. The Iranian sample consisted of 296 Ir...
journal_title：American journal of perinatology
pub_type： 杂志文章,多中心研究
doi：10.1055/s-2001-17856
更新日期：2001-09-01 00:00:00
abstract：:The aim of this study was to evaluate neutrophil chemotaxis and random migration in healthy newborn infants and septic neonates with similar gestational and postnatal age. Possible relationships between chemotactic activity, random migration, causative microorganisms, and clinical course of septic infants were also in...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2000-9507
更新日期：2000-01-01 00:00:00
abstract：:Objective To determine if mandatory online training in electronic fetal monitoring (EFM) improved agreement in documentation between obstetric care providers and nurses on labor and delivery. Methods Health care professionals working in obstetrics at our institution were required to complete a course on EFM interpreta...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0036-1572540
更新日期：2016-07-01 00:00:00
abstract：OBJECTIVE:The Apgar score has been shown to have utility in predicting mortality in the extremely preterm infant in delivery hospital populations, where most mortality occurs within 12 hours of birth. We tested the hypothesis that the 5 minute Apgar score would remain associated with mortality in extremely preterm infa...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0035-1554803
更新日期：2015-11-01 00:00:00
abstract：:Objective To assess the additive value of prenatal chromosomal microarray analysis (CMA) for all indications and the likelihood of detecting pathologic copy number variations (CNVs) based on specific indications. Methods A retrospective analysis was performed on amniocentesis and chorionic villi sampling results obtai...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0036-1586501
更新日期：2017-03-01 00:00:00
abstract：:The Diabetes in Pregnancy Study Group of North America (DPSG-NA) was founded in 1997 in San Antonio, Texas, out of the recognition that the field of maternal-fetal medicine should support and conduct research to address the specialized needs of pregnant women with type 1, type 2, or gestational diabetes mellitus. Sinc...
journal_title：American journal of perinatology
pub_type： 历史文章,杂志文章
doi：10.1055/s-0036-1585082
更新日期：2016-11-01 00:00:00
abstract：OBJECTIVES:Widened pulse pressure is generally associated with patent ductus arteriosus (PDA). Surprisingly, this is often not true for preterm infants during the first week of life when systolic and diastolic pressures are both reduced and pulse pressure may remain unchanged. STUDY DESIGN:This is a retrospective, obs...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0038-1677475
更新日期：2019-11-01 00:00:00
abstract：:The findings of hyperechoic and enlarged fetal kidneys on routine antenatal ultrasonography is a non-specific finding that alerts the physician to a differential diagnosis of various genetic and non-genetic disorders, including fetal polycystic disease and Beckwith-Wiedeman syndrome. Detection of fetal or neonatal pol...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-994309
更新日期：1996-04-01 00:00:00
abstract：OBJECTIVE: This study aimed to examine the effects of interpregnancy weight change on pregnancy outcomes, including recurrent preeclampsia, preterm birth, small-for-gestational age (SGA), large-for-gestational age (LGA), and cesarean delivery, among women with a history of preeclampsia. We also evaluated whether these ...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0040-1713000
更新日期：2020-06-10 00:00:00
abstract：:A case of massive hydramnios involving a twin-twin transfusion syndrome is presented with death of the larger twin and the development of hydrops fetalis in the surviving smaller twin. The amniotic fluid volume of the surviving twin became normal and the hydrops fetalis resolved spontaneously in utero. Concomitant wit...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-999457
更新日期：1990-04-01 00:00:00
abstract：:End-stage renal disease complicates only a small percentage of pregnancies, but, of these, virtually all become anemic due to a deficiency in erythropoietin. Erythropoietin has been shown to correct anemia due to renal disease in nonpregnant patients. We report two cases of erythropoietin use during pregnancy complica...
journal_title：American journal of perinatology
pub_type： 杂志文章,评审
doi：10.1055/s-2007-994392
更新日期：1995-01-01 00:00:00
abstract：OBJECTIVE: The objective of this study was to compare complications and mortality in neonates with hypoxic ischemic encephalopathy (HIE) on extracorporeal membrane oxygenation (ECMO) who did and did not receive therapeutic hypothermia (TH). STUDY DESIGN: The Extracorporeal Life Support Organization registry was querie...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0037-1607197
更新日期：2018-02-01 00:00:00
abstract：OBJECTIVE:To quantify the potential cost savings if azithromycin is substituted for erythromycin in women with preterm premature rupture of membranes (PPROM). STUDY DESIGN:Secondary analysis of a multicentered study investigating magnesium sulfate for the prevention of cerebral palsy in premature infants. All patients...
journal_title：American journal of perinatology
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1055/s-0038-1667369
更新日期：2019-01-01 00:00:00
abstract：OBJECTIVE: The study objective was to assess the correlation between hypernatremia during the first week of life and neurodevelopmental outcomes at 18 months of corrected age in premature infants. STUDY DESIGN: A retrospective observational study of preterm infants born at less than 32 weeks of gestation who had a neu...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0040-1716845
更新日期：2020-09-24 00:00:00
abstract：:Phototherapy is one of the most common therapeutic interventions in modern neonatal medicine. Analysis of physiological responses to phototherapy requires understanding the physical effects of incident light under different modes of environmental control. In this study, we tested the effect of initiation of photothera...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-994402
更新日期：1995-01-01 00:00:00
abstract：OBJECTIVE:To determine the effect of increasing maternal obesity, including superobesity (body mass index [BMI] ≥ 50 kg/m2), on perinatal outcomes in women with diabetes. STUDY DESIGN:Retrospective cohort study of birth records for all live-born nonanomalous singleton infants ≥ 37 weeks' gestation born to Missouri res...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0033-1347363
更新日期：2014-03-01 00:00:00
abstract：:Objective To evaluate if in high-risk non-extracorporeal membrane oxygenation (ECMO)-treated congenital diaphragmatic hernia (CDH) survivors, ventilatory time (VT) is correlated to and can be used as clinical marker of neurodevelopmental delay at 2 years of age. Study Design Cohort study was conducted between 2008 and...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0036-1586120
更新日期：2017-02-01 00:00:00
abstract：:Primary genital herpes simplex virus (HSV) infection in pregnancy is associated with an increased risk of vertical transmission to the fetus, especially with rupture of membranes. Two cases of primary herpes and two cases of recurrent herpes in pregnancy with preterm premature rupture of membranes and expectant manage...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2002-33090
更新日期：2002-07-01 00:00:00
abstract：:We studied Stem cell factor (SCF) levels in 15 mother-newborn pairs, 15 healthy adult controls, and 16 newborn with bacterial sepsis. SCF levels were also determined in six newborns with sepsis before and after completion of treatment. SCF levels (pg/mL) were found to be 2141 +/- 529 in cord blood, 1385 +/- 314 in mot...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-993970
更新日期：1998-07-01 00:00:00
abstract：:From July 1, 1990, to July 1, 1993, we analyzed the results of fibrinogen levels, prothrombin time, and partial thromboplastin time in patients with severe preeclampsia, at least one platelet count less than 100,000/microL, and no signs of abruption or hemorrhage. Analysis was by Pearson's correlation coefficient and ...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-994457
更新日期：1995-05-01 00:00:00
abstract：:Aim To determine the challenges, if any, in translating the benefits of surfactant replacement therapy (SRT) to a resource-limited setting. Method This was a retrospective descriptive study comparing the outcome of 75 cases who received surfactant and 69 controls who did not at the University Hospital of the West Indi...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0036-1598023
更新日期：2017-07-01 00:00:00
abstract：:Arteriovenous malformations of the Vein of Galen continue to present diagnostic and therapeutic challenges in the neonatal period. Approximately 40-50% of all malformations of the Vein of Galen present in the neonatal period, usually with congestive heart failure. These neonates represent the most severe cases and are...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2000-13456
更新日期：2000-01-01 00:00:00
abstract：:Acute mitral regurgitation due to ruptured chordae tendineae is a dramatic and life-threatening clinical situation. Rarely does this complication occur during pregnancy. We present a case of a 30-year-old woman in week 31 of her pregnancy who developed acute mitral regurgitation, secondary to bacterial endocarditis an...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-994418
更新日期：1995-03-01 00:00:00
abstract：:Seven sociodemographic and behavioral factors that may explain the increased risk of preterm deliveries among black women were examined using data from a national sample of 5823 married mothers who responded to the 1980 National Natality Survey (NNS) Questionnaire. There was a twofold increase in the rate of preterm d...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-999412
更新日期：1991-09-01 00:00:00
abstract：:In order to assess the prognosis of hypertension first documented during labor, an inception cohort of all women with hypertension complicating pregnancy was assembled. In this cohort, even extreme elevations of blood pressure, regardless of the degree of proteinuria, were not associated with either maternal or fetal ...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-999799
更新日期：1987-10-01 00:00:00
abstract：:The Roberts-SC phocomelia syndrome (pseudothalidomide syndrome) is a rare, usually lethal condition involving short limbs and occasional hydrocephalus. Presented is a case in which prenatal sonographic findings were highly suggestive of this syndrome, although not definite. In this fetus, findings of hydrocephalus, sh...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-999392
更新日期：1991-07-01 00:00:00
abstract：OBJECTIVE:The objective of this study was to investigate whether maternal bronchial asthma increases the risk for long-term respiratory morbidity of the offspring. STUDY DESIGN:A population-based cohort study compared the incidence of long-term pediatric hospitalizations due to respiratory disease of the offspring of ...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0038-1639507
更新日期：2018-09-01 00:00:00
