当前位置： SCI文献检索 > AMERICAN JOURNAL OF PERINATOLOGY期刊下所有文献 > Challenges Faced in Translating the Benefits of Surfactant Replacement Therapy to a Resource-Limited Setting.

Challenges Faced in Translating the Benefits of Surfactant Replacement Therapy to a Resource-Limited Setting.

Abstract：

:Aim To determine the challenges, if any, in translating the benefits of surfactant replacement therapy (SRT) to a resource-limited setting. Method This was a retrospective descriptive study comparing the outcome of 75 cases who received surfactant and 69 controls who did not at the University Hospital of the West Indies during the period 2001 to 2011. Descriptive analyses were performed. Statistical significance was taken at the level p < 0.05. Results Only 13% of neonates with respiratory distress syndrome received surfactant therapy. The median time of surfactant administration was 16.5 hours (interquartile range: 6-37 hours). The mean ± standard deviation time between repeat doses was 19.1 ± 14 hours. There was no difference in mortality between cases (67%) and controls (59%) (p = 0.32). However, the cases who survived were less mature (28.3 ± 2 weeks) and less clinically stable (CRIB II [Clinical Risk Index for Babies] score: 8.2 ± 3) than their controls who survived (30.0 ± 2 weeks; CRIB II score: 6.0 ± 3) (p = 0.01). There was no difference in mean gestational age or CRIB II scores between nonsurviving cases and controls. A high incidence of sepsis, pneumothoraces, and pulmonary hemorrhage was noted in both cases and controls. Conclusion SRT did not improve the overall outcome in preterm neonates treated with RDS. Challenges encountered in optimizing SRT included affordability and accessibility of surfactant, supportive equipment, and supportive therapies, as well as a high incidence of complications related to prematurity.

journal_name

Am J Perinatol

journal_title

American journal of perinatology

authors

Hamilton N,Trotman H

doi

10.1055/s-0036-1598023

subject

Has Abstract

pub_date

2017-07-01 00:00:00

pages

742-748

issue

8

eissn

0735-1631

issn

1098-8785

journal_volume

34

pub_type

杂志文章

相关文献

AMERICAN JOURNAL OF PERINATOLOGY文献大全
  • The July Effect on Maternal Peripartum Complications before and after Resident Duty Hour Reform: A Population-Based Retrospective Cohort Study.

    abstract：:Objective To compare maternal birth complications early versus late in the academic year and to evaluate the impact of resident work hour limitation on the "July effect." Study Design We conducted a retrospective, population-based cohort study of 628,414 singleton births in Washington State from 1987 to 2012 measuring...

    journal_title：American journal of perinatology

    pub_type： 杂志文章

    doi：10.1055/s-0037-1598244

    authors： Peltan ID,Brown CE,Burke AK,Chow EJ,Rowhani-Rahbar A,Crull MR

    更新日期：2017-07-01 00:00:00

  • An Early Investigation into Possible Alternatives to Stapled Hysterotomy in Open Fetal Surgery.

    abstract：PURPOSE:We hypothesized that surgical energy could be used to create hysterotomies in open fetal surgery. STUDY DESIGN:Initial studies compared the LigaSure Impact and Harmonic ACE + 7 Shears in the efficiency of hysterotomy and thermal damage. Pregnant ewes at an estimated gestational age (EGA) of 116 to 120 days (te...

    journal_title：American journal of perinatology

    pub_type： 杂志文章

    doi：10.1055/s-0038-1673664

    authors： Church JT,McLeod JS,Coughlin MA,Bergin IL,Perkins EM,Hoffman HR,Bilger M,Rojas-Peña A,Treadwell MC,Berman DR,Jarboe MD,Mychaliska GB,Perrone EE

    更新日期：2019-06-01 00:00:00

  • Congenital brucellosis: a rare cause of respiratory distress in neonates.

    abstract：:Brucellosis represents a rare cause of neonatal infection. In this article we report a very unusual case of congenital infection due to BRUCELLA MELITENSIS in a term neonate presenting after birth with severe respiratory distress and radiological manifestations (lobar consolidation and diffuse interstitial infiltratio...

    journal_title：American journal of perinatology

    pub_type： 杂志文章

    doi：10.1055/s-2007-984407

    authors： Sarafidis K,Agakidis C,Diamanti E,Karantaglis N,Roilides E

    更新日期：2007-08-01 00:00:00

  • Are maternal serum troponin I levels affected by vaginal or cesarean delivery?

    abstract：:Our objective was to describe the change in the level of troponin I in patients who undergo a vaginal or cesarean delivery. We obtained troponin I levels on admission and 1 hour after delivery in women undergoing vaginal and cesarean deliveries. Exclusion criteria included <37 weeks' gestation, a history of cardiac di...

    journal_title：American journal of perinatology

    pub_type： 杂志文章

    doi：10.1055/s-2004-820507

    authors： Koscica KL,Bebbington M,Bernstein PS

    更新日期：2004-01-01 00:00:00

  • Temporal Profile of Early Pulmonary Hypertension in Preterm Infants.

    abstract：:Objective The objective of this study was to study the temporal profile of pulmonary hypertension (PH) in preterm infants. Study Design Infants < 28 weeks were screened for early PH at 10 to 14 days of life. Infants with early PH (n = 10) and gestationally matched controls (n = 18) underwent serial echocardiography ev...

    journal_title：American journal of perinatology

    pub_type： 杂志文章

    doi：10.1055/s-0036-1581079

    authors： Mirza H,Ziegler J,Ford S,Padbury J,Tucker R,Laptook A

    更新日期：2016-07-01 00:00:00

  • Midtrimester genetic amniocentesis of a twin gestation complicated by immediate severe fetal bradycardia with subsequent associated fetal anomalies.

    abstract：:We present an unusual complication of midtrimester genetic amniocentesis of a monochorionic twin gestation in which prolonged fetal bradycardia of 60 to 80 beats per minute sustained over two hours was associated with multiple subsequent fetal anomalies. These included: microcephaly, bilateral closed-lip schizencephal...

    journal_title：American journal of perinatology

    pub_type： 杂志文章

    doi：10.1055/s-2007-994354

    authors： Sherer DM,Salafia CM

    更新日期：1996-08-01 00:00:00

  • Use of noninvasive high-frequency ventilation in the neonatal intensive care unit: a retrospective review.

    abstract：OBJECTIVE:The aim of the article is to review the effectiveness of neonatal noninvasive high-frequency ventilation (NIHFV) in preventing endotracheal mechanical ventilation. STUDY DESIGN:Retrospective case series including all 79 instances of NIHFV use at four participating centers between July 2010 and September 2012...

    journal_title：American journal of perinatology

    pub_type： 杂志文章

    doi：10.1055/s-0034-1381317

    authors： Mukerji A,Singh B,Helou SE,Fusch C,Dunn M,Belik J,Shah V

    更新日期：2015-02-01 00:00:00

  • Prenatal MRI evaluation of congenital diaphragmatic hernia.

    abstract：:The objective of this paper is to evaluate the efficacy of various magnetic resonance imaging (MRI) sequences and the general usefulness of prenatal MRI in determining the position of the fetal liver and visualizing lung tissue in fetuses who have congenital diaphragmatic hernia (CDH). This was a retrospective review ...

    journal_title：American journal of perinatology

    pub_type： 杂志文章

    doi：10.1055/s-1999-6821

    authors： Hubbard AM,Crombleholme TM,Adzick NS,Coleman BG,Howell LJ,Meyer JS,Flake AW

    更新日期：1999-01-01 00:00:00

  • Maternal and fetal tuberous sclerosis complicating pregnancy: a case report and overview of the literature.

    abstract：:Tuberous sclerosis complex (TSC) is an autosomal-dominant phakomatosis that can result in cardiac and central nervous system lesions and may adversely impact fetal and maternal health. We report a case of a 19-year-old primagravida with TSC whose pregnancy was complicated by preeclampsia, preterm labor, and fetal demi...

    journal_title：American journal of perinatology

    pub_type： 杂志文章,评审

    doi：10.1055/s-2005-861572

    authors： King JA,Stamilio DM

    更新日期：2005-02-01 00:00:00

  • Outcome of Neonates with Vein of Galen Malformation Presenting with Severe Heart Failure: A Case Series.

    abstract：BACKGROUND:Neonatal presentation of vein of Galen aneurysmal malformations (VGAMs) complicated by cardiac failure and pulmonary hypertension is frequently associated with a poor prognosis. Interventional neuroradiology with embolization can offer a chance for survival, although neurological damage can represent a limit...

    journal_title：American journal of perinatology

    pub_type： 杂志文章

    doi：10.1055/s-0038-1666813

    authors： De Rosa G,De Carolis MP,Tempera A,Pedicelli A,Rollo M,Morena TC,Luca E,De Luca D,Conti G,Piastra M

    更新日期：2019-01-01 00:00:00

  • Logothetopulos pack for the management of uncontrollable postpartum hemorrhage.

    abstract：:This is the first reported case in which a Logothetopulos pack was utilized to achieve pelvic hemostasis in a patient requiring a cesarean hysterectomy for placenta accreta with postpartum hemorrhage. The Logothetopulos pack is an easily constructed gauze tamponade method that proved to be life-saving in this case. ...

    journal_title：American journal of perinatology

    pub_type： 杂志文章

    doi：10.1055/s-2007-999514

    authors： Robie GF,Morgan MA,Payne GG Jr,Wasemiller-Smith L

    更新日期：1990-10-01 00:00:00

  • A Comparison of the Nulliparous-Term-Singleton-Vertex and Society of Maternal-Fetal Medicine Cesarean Birth Metrics Based on Hospital Size.

    abstract：OBJECTIVE: The purpose of this study was to compare the nulliparous-term-singleton-vertex (NTSV) and the Society of Maternal-Fetal Medicine (SMFM) cesarean birth metrics as tools for quality improvement efforts based on hospital size. MATERIALS AND METHODS: Cesarean birth rates from 275 hospitals from six states were ...

    journal_title：American journal of perinatology

    pub_type： 杂志文章,多中心研究

    doi：10.1055/s-0037-1607985

    authors： Shields LE,Walker S,Hedriana HL,Wiesner S,Pelletreau B,Hitti J,Benedetti TJ

    更新日期：2018-03-01 00:00:00

  • What about the Misgav-Ladach surgical technique in patients with previous cesarean sections?

    abstract：OBJECTIVE:The Misgav-Ladach technique is recommended worldwide to perform cesarean sections but there is no consensus about the appropriate technique to use in patients with previous cesarean sections. This study evaluated the feasibility of the Misgav-Ladach technique in patients with previous cesarean sections. STUD...

    journal_title：American journal of perinatology

    pub_type： 临床试验,杂志文章

    doi：10.1055/s-0032-1323580

    authors： Bolze PA,Massoud M,Gaucherand P,Doret M

    更新日期：2013-03-01 00:00:00

  • Prophylactic amnioinfusion in preganancies complicated by chorioamnionitis: a prospective randomized trial.

    abstract：:The objective of this article is to prospectively investigate the efficacy of amnioinfusion as a means to reduce febrile morbidity in pregnancies complicated by chorioamnionitis. All laboring patients with a temperature > or =100.1 degrees F were approached for study participation. Exclusion criteria included amnionit...

    journal_title：American journal of perinatology

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1055/s-2007-994085

    authors： Parilla BV,McDermott TM

    更新日期：1998-01-01 00:00:00

  • Perceptions of webcams in the neonatal intensive care unit: here's looking at you kid!

    abstract：INTRODUCTION:Many tertiary neonatal units employ a restricted visiting policy. Webcams have previously been implemented in the neonatal unit setting in several countries. OBJECTIVES:This study aims to determine the views from parents, physicians, and nursing staff before implementation of a webcam system. METHODS:A q...

    journal_title：American journal of perinatology

    pub_type： 杂志文章

    doi：10.1055/s-0034-1376388

    authors： Hawkes GA,Livingstone V,Ryan CA,Dempsey EM

    更新日期：2015-02-01 00:00:00

  • The Role of Surfactant Therapy in Nonrespiratory Distress Syndrome Conditions in Neonates.

    abstract：:While treatment of respiratory distress syndrome (RDS) with surfactant in premature neonates is well established, evidence for its use in non-RDS conditions, especially in the term neonate, has been less abundant. The last published review on a PubMed search was in 2001. In this review, we comprehensively and critical...

    journal_title：American journal of perinatology

    pub_type： 杂志文章,评审

    doi：10.1055/s-0035-1556883

    authors： Keiser A,Bhandari V

    更新日期：2016-01-01 00:00:00

  • The Impact of Hepatitis C Virus Infection on Buprenorphine Dose in Pregnancy.

    abstract：OBJECTIVE:Buprenorphine (BUP) is commonly used for opioid maintenance therapy in pregnancy. Our goal was to determine whether liver dysfunction related to hepatitis C virus (HCV) infection impacts BUP dosing requirements in pregnancy. STUDY DESIGN:This was a retrospective cohort study of pregnant women with antenatal ...

    journal_title：American journal of perinatology

    pub_type： 杂志文章

    doi：10.1055/s-0039-1698838

    authors： McDowell ML,Tonismae TR,Slaven JE,Abernathy MP,Shanks AL,Benjamin TD,Quinney SK

    更新日期：2020-01-01 00:00:00

  • Society for Maternal-Fetal Medicine's Fellow Research Series 2018: Manuscripts of the Year.

    abstract：: ...

    journal_title：American journal of perinatology

    pub_type： 社论

    doi：10.1055/s-0038-1676585

    authors： Metz TD,Gill L,Silver RM,Society for Maternal-Fetal Medicine Fellowship Affairs Committee.

    更新日期：2019-01-01 00:00:00

  • Decision to Incision and Risk for Fetal Acidemia, Low Apgar Scores, and Hypoxic Ischemic Encephalopathy.

    abstract：OBJECTIVE: This study aimed to assess risk for fetal acidemia, low Apgar scores, and hypoxic ischemic encephalopathy based on decision-to-incision time interval in the setting of emergency cesarean delivery. STUDY DESIGN: This unplanned secondary analysis of the Maternal-Fetal Medicine Units prospective observational ...

    journal_title：American journal of perinatology

    pub_type： 杂志文章

    doi：10.1055/s-0040-1717068

    authors： Bousleiman S,Rouse DJ,Gyamfi-Bannerman C,Huang Y,D'Alton ME,Siddiq Z,Wright JD,Friedman AM

    更新日期：2020-09-21 00:00:00

  • Outcomes after Neonatal Seizures in Infants Less Than 29 Weeks' Gestation: A Population-Based Cohort Study.

    abstract：OBJECTIVE:The aim of this study was to evaluate the association between neonatal seizure and neurodevelopmental impairment (NDI) at 18 to 24 months in extremely preterm neonates. The association between anticonvulsants use and NDI was also assessed. STUDY DESIGN:In this retrospective cohort study of infants born at <2...

    journal_title：American journal of perinatology

    pub_type： 杂志文章

    doi：10.1055/s-0038-1667107

    authors： Iwami H,Isayama T,Lodha A,Canning R,Abou Mehrem A,Lee SK,Synnes A,Shah PS,Canadian Neonatal Network and Canadian Neonatal Follow-Up Network Investigators.

    更新日期：2019-01-01 00:00:00

  • Prevention of RhD Alloimmunization: A Comparison of Four National Guidelines.

    abstract：OBJECTIVE: The objective of this study was to compare national guidelines on the prevention of RhD alloimmunization. STUDY DESIGN: We performed a review of four national guidelines on prevention of alloimmunization from the American Congress of Obstetricians and Gynecologists, Royal College of Obstetricians and Gynaec...

    journal_title：American journal of perinatology

    pub_type： 杂志文章,评审

    doi：10.1055/s-0037-1606609

    authors： Sperling JD,Dahlke JD,Sutton D,Gonzalez JM,Chauhan SP

    更新日期：2018-01-01 00:00:00

  • Effects of yoga intervention during pregnancy: a review for current status.

    abstract：OBJECTIVES:The purpose of this article is to review all randomized control trials (RCTs) that have looked at the health effects of yoga on pregnancy, and to present their evidence on the specific ways in which pregnant women, and their infants can benefit from yoga intervention. The purpose is also to determine whether...

    journal_title：American journal of perinatology

    pub_type： 杂志文章,评审

    doi：10.1055/s-0034-1396701

    authors： Jiang Q,Wu Z,Zhou L,Dunlop J,Chen P

    更新日期：2015-05-01 00:00:00

  • Fetal death after normal biophysical profile.

    abstract：:Presented are three cases of fetal death, all of which occurred within 3 days of a normal biophysical profile. Despite the excellent record of this antepartum test in predicting fetal well-being, there is a low incidence of false-negative tests; increasing the frequency of testing will not prevent all false-negative t...

    journal_title：American journal of perinatology

    pub_type： 杂志文章

    doi：10.1055/s-2007-999352

    authors： Watson WJ,Katz VL,Bowes WA Jr

    更新日期：1991-03-01 00:00:00

  • Obestatin Reduces Intestinal Damage in Experimental Necrotizing Enterocolitis in Newborn Rats.

    abstract：OBJECTIVE:To investigate the effect of pretreatment with obestatin (OB), an endogenous hormone also found in mother's milk, in experimental necrotizing enterocolitis (NEC). STUDY DESIGN:Pups were randomized into four groups: control, OB-control, NEC, and OB-NEC. NEC was induced by asphyxia and hypothermia in the NEC a...

    journal_title：American journal of perinatology

    pub_type： 杂志文章

    doi：10.1055/s-0038-1676491

    authors： Korkut S,Özdemir A,Yay AH,Yalçın B,Ceylan M,Korkmaz L,Yazıcı C,Güntürk İ,Kurtoğlu S

    更新日期：2019-09-01 00:00:00

  • Do fiber-enriched diabetic diets have glucose-lowering effects in pregnancy?

    abstract：:A fiber-enriched diabetic diet that contained a modest increase in dietary fiber and a commercially available fiber supplement was studied in pregnant diabetic women for its potential glucose-lowering effects. Noninsulin-requiring gestational diabetic patients were placed on a fiber-enriched diet of increasing fiber c...

    journal_title：American journal of perinatology

    pub_type： 临床试验,杂志文章

    doi：10.1055/s-2007-994738

    authors： Reece EA,Hagay Z,Caseria D,Gay LJ,DeGennaro N

    更新日期：1993-07-01 00:00:00

  • Birth weight and gestational age standards based on regional perinatal network data: an analysis of risk factors.

    abstract：:The most frequently used set of gestational age-birth weight curves in the United States is the Colorado (C) standard published in 1963. To investigate the usefulness of this standard in an urban population at sea level, we examined the birth weight vs gestational age data from 56,675 singleton liveborn infants born b...

    journal_title：American journal of perinatology

    pub_type： 杂志文章

    doi：10.1055/s-2007-999785

    authors： Raju TN,Winegar A,Seifert L,Miller S

    更新日期：1987-07-01 00:00:00

  • Does Universal Coverage Mitigate Racial Disparities in Potentially Avoidable Maternal Complications?

    abstract：OBJECTIVE: Potentially avoidable maternity complications (PAMCs) have been validated as an indicator of access to quality prenatal care. African-American mothers have exhibited a higher incidence of PAMCs, which has been attributed to unequal health coverage. The objective of this study was to assess if racial disparit...

    journal_title：American journal of perinatology

    pub_type： 杂志文章

    doi：10.1055/s-0040-1701195

    authors： Ranjit A,Andriotti T,Madsen C,Koehlmoos T,Staat B,Witkop C,Little SE,Robinson J

    更新日期：2020-01-27 00:00:00

  • Identification of a Pivotal Period in the Oral Feeding Progression of Preterm Infants.

    abstract：OBJECTIVE:Preterm infants are at risk of encountering oral feeding difficulties which impede on the transition to independent oral feeds. The objective of this study was to identify a pivotal period where regressions are most likely to occur during their oral feeding progression. STUDY DESIGN:This is a retrospective s...

    journal_title：American journal of perinatology

    pub_type： 杂志文章

    doi：10.1055/s-0038-1669947

    authors： Fucile S,Phillips S,Bishop K,Jackson M,Yuzdepski T,Dow K

    更新日期：2019-04-01 00:00:00

  • Interpregnancy Body Mass Index Changes: Distribution and Impact on Adverse Pregnancy Outcomes in the Subsequent Pregnancy.

    abstract：OBJECTIVE:To examine the change in body mass index (BMI) categories between pregnancies and its effect on adverse pregnancy outcomes. STUDY DESIGN:We performed a retrospective cohort study of women with two consecutive deliveries from 2005 to 2010. Analysis was limited to women with BMI recorded at <24 weeks for both ...

    journal_title：American journal of perinatology

    pub_type： 杂志文章

    doi：10.1055/s-0038-1670634

    authors： Bender W,Hirshberg A,Levine LD

    更新日期：2019-04-01 00:00:00

  • The Impact of Sperm and Egg Donation on the Risk of Pregnancy Complications.

    abstract：OBJECTIVE:The aim of this study was to evaluate obstetric outcomes in relation to the extent of donor sperm exposure with and without egg donation. MATERIALS AND METHODS:This is a retrospective cohort study in a single tertiary care center. All women with a singleton pregnancy who conceived following sperm donation (S...

    journal_title：American journal of perinatology

    pub_type： 杂志文章

    doi：10.1055/s-0038-1667029

    authors： Fishel Bartal M,Sibai BM,Bart Y,Shina A,Mazaki-Tovi S,Eisen IS,Hendler I,Baum M,Schiff E

    更新日期：2019-01-01 00:00:00