Abstract：
:Gestational diabetes mellitus (GDM) has increased dramatically in the past 20 years together with the obesity epidemic. Mirroring the increase in incidence of GDM is increasing use of endocrine disrupting chemicals (EDCs). EDCs are structurally similar to endogenous hormones and interfere with synthesis, secretion, activity, or elimination of natural hormones, resulting in adverse health effects, including diabetes, obesity, developmental disorders, etc. Although the association between bisphenol A (BPA), a well-studied EDC, and type 2 diabetes has been repeatedly investigated in epidemiological and animal studies, there is a dearth of studies examining EDCs and GDM. In fact, the impact of environmental toxins on perinatal health outcomes has largely been overlooked.Recognizing this research gap, the American College of Obstetricians and Gynecologists, American Society for Reproductive Medicine, and International Federation of Gynecology and Obstetrics recently joined leading scientists and clinicians in a call for action to prioritize research in the consequences of exposure to toxic environmental agents on women's health. Evidence is emerging to suggest signaling molecules and EDCs are involved in the control of microRNA (miRNA) expression in trophoblast cells. We reviewed existing scientific evidence of EDCs as a risk factor for GDM as well as the potential role of miRNA in this association.
journal_name
Am J Perinatoljournal_title
American journal of perinatologyauthors
Ehrlich S,Lambers D,Baccarelli A,Khoury J,Macaluso M,Ho SMdoi
10.1055/s-0036-1586500subject
Has Abstractpub_date
2016-11-01 00:00:00pages
1313-1318issue
13eissn
0735-1631issn
1098-8785journal_volume
33pub_type
杂志文章,评审abstract：:Pleural effusion is not an uncommon complication of percutaneous intravenous catheters in neonates. Umbilical venous catheters (UVCs) are associated with pleural effusion following abnormal placement in the left atrium or pulmonary veins due to venous obstruction. We report for the first time a case of right-sided ple...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-992174
更新日期：2007-11-01 00:00:00
abstract：:We report a case that presents clear evidence of an intrauterine infection of twin fetuses with an enterovirus. The mother had signs and symptoms of chorioamniotitis at 34 weeks' gestation. Coxsackie virus, group B type 1 (CVB1), was cultured from amniotic fluid obtained by transabdominal amniocentesis when the membra...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-994407
更新日期：1995-03-01 00:00:00
abstract：:We describe a case of transient hyperinsulinism in an asphyxiated newborn infant with hypoglycemia. Although hypoglycemia in birth asphyxiated infants is generally attributed to depletion of glycogen stores, we observed severe hyperinsulinism associated with the hypoglycemia. The hypoglycemia was refractory to high gl...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2001-15504
更新日期：2001-06-01 00:00:00
abstract：OBJECTIVE: Studies demonstrate shorter time to delivery with concurrent use of misoprostol and cervical Foley catheter. However, concurrent placement may not be feasible. If misoprostol is used to start an induction, little is known regarding the benefit of sequentially using Foley catheter. We examine obstetrical outc...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0040-1713818
更新日期：2020-06-28 00:00:00
abstract：:Conventional interval dosing (CID) and extended interval dosing (EID) of gentamicin were compared in preterm infants. Gentamicin peak and trough levels, serum creatinine, urine output, and hearing screens were obtained in 40 preterm infants. Results suggest that EID is safe, provides gentamicin levels in desirable ran...
journal_title：American journal of perinatology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1055/s-2004-820515
更新日期：2004-02-01 00:00:00
abstract：:We present a case of congenital parvovirus B19 infection in a term neonate manifested with isolated massive hydrothorax and mild anemia. Parvovirus B19 DNA was detected in maternal and neonatal blood as well as in pleural fluid despite lack of suggestive serology. ...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0028-1085621
更新日期：2008-10-01 00:00:00
abstract：:We report about two newborns with sudden onset of inability of mechanical ventilation due to transient chest wall rigidity after fentanyl i.v. bolus of 2 and 4 microg/kg, respectively, resulting in severe hypoxemia and secondary bradycardia. A third case developed a rigidity of the tongue after fentanyl bolus, which c...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2000-7289
更新日期：2000-01-01 00:00:00
abstract：OBJECTIVE:The Misgav-Ladach technique is recommended worldwide to perform cesarean sections but there is no consensus about the appropriate technique to use in patients with previous cesarean sections. This study evaluated the feasibility of the Misgav-Ladach technique in patients with previous cesarean sections. STUD...
journal_title：American journal of perinatology
pub_type： 临床试验,杂志文章
doi：10.1055/s-0032-1323580
更新日期：2013-03-01 00:00:00
abstract：:First-trimester prenatal diagnosis was offered to 104 twin pregnancies mainly for advanced maternal age and cytogenetic evaluation of a new fertilization technique. Chorionic villus sampling (CVS) was performed transcervically (35%), transabdominally (23%), or by combination of these two techniques (42%). Although no ...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-994380
更新日期：1996-10-01 00:00:00
abstract：:Diagnosis of fetal pulmonary hypoplasia could be of great benefit to the obstetrician in the management of those pregnancies complicated by prolonged preterm ruptured membranes. Ultrasonography and magnetic resonance imaging were employed for fetal diagnosis of pulmonary hypoplasia and we were unable to predict accura...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-994689
更新日期：1993-01-01 00:00:00
abstract：PURPOSE:We hypothesized that surgical energy could be used to create hysterotomies in open fetal surgery. STUDY DESIGN:Initial studies compared the LigaSure Impact and Harmonic ACE + 7 Shears in the efficiency of hysterotomy and thermal damage. Pregnant ewes at an estimated gestational age (EGA) of 116 to 120 days (te...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0038-1673664
更新日期：2019-06-01 00:00:00
abstract：:We present an unusual complication of midtrimester genetic amniocentesis of a monochorionic twin gestation in which prolonged fetal bradycardia of 60 to 80 beats per minute sustained over two hours was associated with multiple subsequent fetal anomalies. These included: microcephaly, bilateral closed-lip schizencephal...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-994354
更新日期：1996-08-01 00:00:00
abstract：:We studied Stem cell factor (SCF) levels in 15 mother-newborn pairs, 15 healthy adult controls, and 16 newborn with bacterial sepsis. SCF levels were also determined in six newborns with sepsis before and after completion of treatment. SCF levels (pg/mL) were found to be 2141 +/- 529 in cord blood, 1385 +/- 314 in mot...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-993970
更新日期：1998-07-01 00:00:00
abstract：OBJECTIVE:To determine epidemiology and clinical characteristics of infants with methicillin-susceptible (MSSA) and -resistant Staphylococcus aureus (MRSA) in a level III neonatal intensive care unit (NICU). STUDY DESIGN:All NICU admissions (2001 to 2008) with any positive S. aureus culture were included as cases. Cas...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0032-1304819
更新日期：2012-06-01 00:00:00
abstract：OBJECTIVE:The aim of this article is to evaluate the accuracy, precision, and safety of transcutaneous carbon dioxide tension (TcPCO2) monitoring at different electrode temperatures in preterm infants in the early postnatal period. STUDY DESIGN:A total of 26 neonates with a median birth weight of 974 g (432-1,694 g) a...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0033-1352485
更新日期：2014-05-01 00:00:00
abstract：:The purpose of this study was to examine the maternal risk factors associated with early onset Group B streptococcus (GBS) sepsis and determine the potential impact of intrapartum chemoprophylaxis using these risk factors. Using a computerized perinatal database, 26,525 deliveries over a five-year period (1989 to 1994...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-994433
更新日期：1996-11-01 00:00:00
abstract：:Using first trimester fetal crown-rump length (CRL) measurements as the criterion for gestational dating, rather than menstrual history or neonatal gestational age evaluation after birth, may be a more accurate way of evaluating the accuracy of second or third trimester ultrasonic measurements for gestational age esti...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-994606
更新日期：1994-11-01 00:00:00
abstract：OBJECTIVES:This study aims to compare women with early (13-16 years), late teenage (17-19 years), and adult (25-29 years) pregnancies regarding pregnancy risk factors and reproductive outcomes. METHODS:An observational study, utilizing medical charts and direct interview, conducted in an academic hospital during Janua...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0035-1565917
更新日期：2016-03-01 00:00:00
abstract：OBJECTIVE: The objective of this study was to compare national guidelines on the prevention of RhD alloimmunization. STUDY DESIGN: We performed a review of four national guidelines on prevention of alloimmunization from the American Congress of Obstetricians and Gynecologists, Royal College of Obstetricians and Gynaec...
journal_title：American journal of perinatology
pub_type： 杂志文章,评审
doi：10.1055/s-0037-1606609
更新日期：2018-01-01 00:00:00
abstract：:The estimation of plasma bilirubin concentration in neonates, using a transcutaneous, noninvasive jaundice meter, is significantly affected by many factors, such as gestational age, birthweight, phototherapy, and skin pigmentation. In an attempt to minimize the influence of skin color and hence circumvent the need for...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2008-1040751
更新日期：1994-05-01 00:00:00
abstract：:A study was undertaken in 372 consecutive patients undergoing non-elective cesarean delivery to explore the incidence and nature of conflicts between physician and patient surrounding the decision to undergo non-elective cesarean delivery; to examine the adequacy of informed consent at the time of non-elective cesarea...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-994319
更新日期：1996-04-01 00:00:00
abstract：:We present a rare occurrence of an early-onset extensive cystic hygroma colli with intralesional hemorrhage and a favorable outcome. A 23-year-old primigravida woman was referred for management of a left isolated extensive cystic hygroma colli at 22 weeks' gestation. Amniocentesis revealed a 46, XY karyotype. Ultrasou...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-994077
更新日期：1998-01-01 00:00:00
abstract：:This study was undertaken to determine the plasma and erythrocyte profiles of metabolically important nonesterified polyunsaturated fatty acids (PUFA), that is, free fatty acids, in each trimester of pregnancy and in labor. Blood was drawn from patients in the first, second, and third trimester and in labor. Nonesteri...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2008-1040766
更新日期：1997-11-01 00:00:00
abstract：:This study was conducted to examine the potential effects of expanded Medicaid coverage for low income women. Statewide birth data for 1983 to 1985 were examined to determine the relationship between prenatal care and admissions to neonatal intensive care units (NICUs) and the costs of this care. An NICU sample was co...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-994790
更新日期：1992-07-01 00:00:00
abstract：:The purpose of this study was to compare risk factors between placental abruption and placenta previa among primiparous and multiparous singleton pregnancies. We analyzed data from a population-based retrospective cohort with singleton pregnancies in the United States for 1995 to 2000. Maternal risk factors for placen...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0028-1103156
更新日期：2009-04-01 00:00:00
abstract：:Premature closure of the foramen ovale is a rare cardiac anomaly. Severe right-sided heart failure accounts for the hepatomegaly, ascites, pleural and pericardial effusions, and generalized edema of these hydropic fetuses. Premature closure of the foramen ovale should be a part of the differential diagnosis when unexp...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-994616
更新日期：1994-11-01 00:00:00
abstract：OBJECTIVE:To examine the change in body mass index (BMI) categories between pregnancies and its effect on adverse pregnancy outcomes. STUDY DESIGN:We performed a retrospective cohort study of women with two consecutive deliveries from 2005 to 2010. Analysis was limited to women with BMI recorded at <24 weeks for both ...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0038-1670634
更新日期：2019-04-01 00:00:00
abstract：:We studied 16 women, at 32 weeks' or more gestation who required magnesium sulfate (MgSO4) therapy for preterm labor or preeclampsia. A 60-minute Doppler fetal heart rate (FHR) tracing, analyzed by the Oxford Sonicaid System 8000, was obtained for 1 hour before and 2 hours after each patient received intravenous MgSO4...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-994468
更新日期：1995-07-01 00:00:00
abstract：:Cimetidine therapy used for the treatment of gastric bleeding due to tolazoline therapy in a newborn infant was temporally associated with episodes of severe hypoxemia. It appears likely that the histamine H2 receptor blocked by cimetidine obviated the pulmonary vasodilator effect of tolazoline therapy. ...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-994346
更新日期：1996-07-01 00:00:00
abstract：:We sought to validate center-specific published medians and estimate the effects of sonologist and Doppler measurement techniques on middle cerebral artery (MCA) peak systolic velocity (PSV) values. We studied 154 gravidas with normal singletons who underwent MCA PSV measurement at 18 to 35 weeks' gestation by one of ...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0030-1249365
更新日期：2010-09-01 00:00:00
