Effect of magnesium on fetal heart rate variability using computer analysis.

Abstract:

:We studied 16 women, at 32 weeks' or more gestation who required magnesium sulfate (MgSO4) therapy for preterm labor or preeclampsia. A 60-minute Doppler fetal heart rate (FHR) tracing, analyzed by the Oxford Sonicaid System 8000, was obtained for 1 hour before and 2 hours after each patient received intravenous MgSO4 therapy. Maternal serum Mg2+ levels were obtained at the second monitoring session. Matched paired measures of FHR parameters were compared with the Student's t test. After MgSO4 administration, we noted significant falls in long-term variability, short-term variability, and total acceleration (more than 10 beats/min) counts. Reduced short-term and overall variability occurred in all cases with maternal serum Mg2+ levels more than 4.6 mg/dL. Therapeutic maternal serum Mg2+ levels are linked with decreases in long-term and short-term FHR variability and acceleration counts. These findings should be considered when evaluating resting FHR baseline of patients thus treated.

journal_name

Am J Perinatol

authors

Hiett AK,Devoe LD,Brown HL,Watson J

doi

10.1055/s-2007-994468

subject

Has Abstract

pub_date

1995-07-01 00:00:00

pages

259-61

issue

4

eissn

0735-1631

issn

1098-8785

journal_volume

12

pub_type

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