Abstract:
:Chart review of 73 patients with 3.5 cm or more dilation, intact membranes, and regular contractions at less than 36 weeks. Forty-four (group A) received tocolysis with magnesium sulfate, and 13 of the 44 also received indomethacin. Twenty-nine (group B) received no tocolysis. Obstetric and neonatal outcomes were compared. Demographic factors and admission gestational age, cervical dilation, effacement, and uterine activity were similar. Twenty-one of the 44 in group A versus 3 of 29 in group B had delivery delayed by more than 48 hours (p = 0.002). Group A had a lower incidence of severe respiratory distress syndrome; 4 of 48 babies in group A versus 9 of 32 in group B (p = 0.04; RR = 0.47; confidence interval [CI], 0.2, 1.0). Tocolysis in advanced preterm labor delays delivery by more than 48 hours in 50% of patients. The neonatal benefits of aggressive tocolysis in cases with advanced cervical dilation may outweigh the potential maternal risks of tocolysis, particularly in the setting of extreme prematurity. Delay in delivery enabling steroid enhancement of pulmonary maturity reduces the severity of respiratory distress syndrome.
journal_name
Am J Perinatoljournal_title
American journal of perinatologyauthors
de Veciana M,Porto M,Major CA,Barke JIdoi
10.1055/s-2007-994478subject
Has Abstractpub_date
1995-07-01 00:00:00pages
294-8issue
4eissn
0735-1631issn
1098-8785journal_volume
12pub_type
临床试验,杂志文章abstract:OBJECTIVE:The objective of this article is to evaluate the implementation and acceptability of a universal cervical length (CL) screening program for prediction and prevention of preterm birth (PTB). STUDY DESIGN:We performed a prospective observational study to evaluate the implementation and acceptability of a unive...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0034-1371710
更新日期:2014-12-01 00:00:00
abstract:OBJECTIVE:Advances in neonatology have made possible the survival of neonates with lower gestational ages and birth weights. Nevertheless, findings remain of a sex difference in mortality for premature and low birth weight (LBW) neonates with male sex often associated with poorer outcome (the "male disadvantage"). Thro...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0037-1608876
更新日期:2018-07-01 00:00:00
abstract::Two cases of inadvertent third trimester amniocenteses occurring during attempted spinal tap and culdocentesis are presented. These hitherto undescribed occurrences stress potential complications of these invasive diagnostic procedures in the gravid woman. ...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-994618
更新日期:1993-11-01 00:00:00
abstract::We sought to identify maternal or clinical characteristics of women likely to develop preterm labor (PTL) at <34 weeks' gestation while receiving 17 alpha-hydroxyprogesterone caproate (17P) prophylaxis. Current singleton gestations with prior preterm delivery enrolled for outpatient 17P administration at <27 weeks' ge...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0029-1243306
更新日期:2010-04-01 00:00:00
abstract::The objective of this study was to determine if the rate of preeclampsia is increased in triplet as compared to twin gestations. Fifty-three triplet pregnancies between 1986 and 1993 at The New York Hospital-Cornell Medical Center were reviewed. These were matched for maternal age, parity, and race to twin gestations ...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-994140
更新日期:1997-05-01 00:00:00
abstract:OBJECTIVE: It is well established that women with a previous vaginal delivery have higher success rates in relation to vaginal birth after cesarean than those without. The aim of this study was to examine the effect of past mode of delivery on contractile parameters of human myometrium in vitro. STUDY DESIGN: Myometri...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0039-1694980
更新日期:2021-01-01 00:00:00
abstract:OBJECTIVE: This study aimed to identify differences in sequential integrated screening and early ultrasound markers in monochorionic/diamniotic (MC/DA) pregnancies complicated by twin-to-twin transfusion syndrome (TTTS) and unequal placental sharing (UPS). STUDY DESIGN: Retrospective cohort study of MC/DA pregnancies ...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0040-1718371
更新日期:2020-10-08 00:00:00
abstract:OBJECTIVE:This article compares hemodynamic characteristics of neonates with hypoxic ischemic encephalopathy (HIE) receiving therapeutic hypothermia (TH) with normal versus abnormal brain magnetic resonance imaging (MRI). METHODS:Serial echocardiography (echo) was performed within 24 hours, after 48 to 72 hours of coo...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0038-1629900
更新日期:2018-08-01 00:00:00
abstract::Ehlers-Danlos syndrome type IV (EDS IV) is a rare but serious disorder of connective tissue that is characterized by the abnormal production or secretion of type III collagen. Experience with pregnant patients exhibiting this syndrome is limited. This report describes the successful management of a pregnancy in a woma...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-999756
更新日期:1987-04-01 00:00:00
abstract:OBJECTIVE:Fetal tachyarrhythmias complicate 0.5% of pregnancies, with high morbidity and mortality. We hypothesized that maternal factors may predispose to fetal supraventricular tachycardia (SVT). STUDY DESIGN:We reviewed medical records of all 124 mothers who presented to the Vanderbilt Fetal Cardiology Clinic from ...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0035-1552942
更新日期:2015-11-01 00:00:00
abstract:OBJECTIVE:To compare the efficacy of similar buccal and vaginal misoprostol doses for induction of labor. STUDY DESIGN:Retrospective chart review of 207 consecutive women undergoing term induction of labor with misoprostol. Misoprostol route and dosing were collected. Time to delivery and other labor outcomes (e.g., v...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0038-1675219
更新日期:2019-06-01 00:00:00
abstract:OBJECTIVE: In 2015, Neonatal Resuscitation Program (NRP) recommended laryngeal mask airway (LMA) as an alternative to the endotracheal tube (ETT) in situations where the provider is "unable to intubate and unable to ventilate." LMA insertion is being taught in the NRP routinely. However, endotracheal intubation is the ...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0040-1721379
更新日期:2020-11-29 00:00:00
abstract::Presented are three cases of fetal death, all of which occurred within 3 days of a normal biophysical profile. Despite the excellent record of this antepartum test in predicting fetal well-being, there is a low incidence of false-negative tests; increasing the frequency of testing will not prevent all false-negative t...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-999352
更新日期:1991-03-01 00:00:00
abstract::Myocardial infarction in association with pregnancy in patients with the antiphospholipid syndrome has been reported once previously. Our patient, a 22-year-old multiparous woman, experienced a myocardial infarction in the postpartum period. She fulfilled the criteria for the diagnosis of the antiphospholipid syndrome...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-994522
更新日期:1994-01-01 00:00:00
abstract::The most common mechanism of fetal tachycardia is orthodromic reciprocating tachycardia utilizing an accessory atrioventricular connection, however, data regarding accessory connection location in patients with fetal tachycardia is limited. To investigate the location of accessory connections in fetal tachycardia, pos...
journal_title:American journal of perinatology
pub_type: 临床试验,杂志文章
doi:10.1055/s-2003-40014
更新日期:2003-04-01 00:00:00
abstract::Extremely preterm infants often develop chronic lung disease (CLD) characterized by heterogeneous aeration; poorly supported, floppy airways; and air trapping. High-frequency jet ventilation (HFJV) with high end-expiratory pressure (optimal lung volume strategy [OLVS]) may improve airway patency, lead to better gas di...
journal_title:American journal of perinatology
pub_type: 临床试验,杂志文章
doi:10.1055/s-2006-954821
更新日期:2006-11-01 00:00:00
abstract::We sought to determine the detection (clinical or sonographic) rate of macrosomic newborns (at least 4000 g) and the peripartum factors among those who were or were not identified accurately. We retrospectively reviewed all deliveries over 1 year and all maternal and neonatal charts of macrosomic newborns delivered du...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0028-1095187
更新日期:2009-02-01 00:00:00
abstract::We investigated the correlation of fetal heart rate patterns and fetal acid-base findings with the occurrence of early periventricular/intraventricular hemorrhage and variants. Ninety-five consecutive singleton neonates with birthweights less than or equal to 2000 gm were investigated. One-third of them showed early p...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-999819
更新日期:1986-01-01 00:00:00
abstract::This case-controlled study reviewed 26 cases of uterine rupture at an academic medical center. Controls were selected in a 2:1 design by reviewing the immediate successful vaginal birth after cesarean delivery (VBAC) before and after each case of uterine rupture. At less than 2 hours before delivery or acute uterine r...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-981433
更新日期:2007-05-01 00:00:00
abstract::The manifestations of fetal varicella syndrome usually involve several organ systems, including skin, ocular, neurologic, gastrointestinal, and genitourinary. Although ocular anomalies have been reported to be as high as 68%, manifestations limited to the eyes is extremely rare. Herein we report the case of fetal vari...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-994493
更新日期:1995-09-01 00:00:00
abstract::The purpose of this study is to identify obstetrical factors associated with adverse neurological outcome in < or =1000-g infants. In a 1-year (1992-1993) observational study, the NICHD MFMU Network collected obstetrical risk factors for 486 infants who weighed < or =1000 g at birth and who survived > 2 days. Infants'...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-993833
更新日期:1999-01-01 00:00:00
abstract::The purpose of this study is to compare the effectiveness of double phototherapy versus single conventional phototherapy in decreasing serum bilirubin levels in jaundiced neonates. Forty-two preterm infants who were less than 37 weeks' gestational age and less than 2000 g birthweight with nonhemolytic jaundice were al...
journal_title:American journal of perinatology
pub_type: 临床试验,杂志文章
doi:10.1055/s-2007-994446
更新日期:1995-05-01 00:00:00
abstract::With the increasing survival of extremely premature infants there is a large number of them who are developing chronic lung disease (CLD), but the severity of the lung damage is considerably less than that observed in the classic form of bronchopulmonary dysplasia (BPD). Because many of these infants have only a mild ...
journal_title:American journal of perinatology
pub_type: 杂志文章,评审
doi:10.1055/s-2001-12940
更新日期:2001-01-01 00:00:00
abstract::This study assessed whether the amniotic fluid index (AFI) or the single deepest pocket (SDP) is the best technique to estimate amniotic fluid volume. The AFI and SDP were compared to a dye-determined or directly measured amniotic fluid volume. A PUBMED search from 1990 to 2006 was conducted using the search terms "si...
journal_title:American journal of perinatology
pub_type: 杂志文章,评审
doi:10.1055/s-2007-986689
更新日期:2007-10-01 00:00:00
abstract:OBJECTIVE: New treatments are needed for multidrug-resistant (MDR) gram-negative infections in neonates. Ceftolozane/tazobactam is a β-lactam/β-lactamase inhibitor combination that has broad-spectrum activity against most common gram-negative bacteria, including MDR strains. We evaluated pharmacokinetics (PK) and safet...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0039-3402719
更新日期:2020-01-07 00:00:00
abstract::Introduction First-trimester ultrasound (US) for anatomy assessment may improve anomaly detection, but it may also increase overall US utilization. We sought to assess the utility of first-trimester US for evaluation of fetal anatomy. Materials and Methods A decision analytic model was created to compare first- plus s...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0036-1579652
更新日期:2016-08-01 00:00:00
abstract:OBJECTIVE:We aimed to compare the rates of "surfactant treated respiratory disease" and other neonatal morbidities among moderately preterm (MPT) infants exposed to no, partial, or a complete course of antenatal corticosteroids (ANS). STUDY DESIGN:This observational cohort study evaluated MPT infants (290/7-336/7 week...
journal_title:American journal of perinatology
pub_type: 杂志文章,多中心研究
doi:10.1055/s-0038-1642059
更新日期:2018-10-01 00:00:00
abstract:OBJECTIVE:The definition of postpartum hemorrhage (PPH) was developed more than 50 years ago. Since then, the obstetric population has changed dramatically. We sought to determine how well we estimated blood loss (EBL) and find thresholds predicting need for transfusion. STUDY DESIGN:We performed a prospective cohort ...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0035-1552940
更新日期:2015-11-01 00:00:00
abstract::A case is presented of a primigravida with transient diabetes insipidus, gestational hypertension, and multiple seizures resistant to magnesium sulfate and diazepam. After addition of phenytoin, no further seizures occurred. Transient diabetes insipidus in pregnancy has been previously associated with hypertension, li...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-999504
更新日期:1990-07-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Congenital pulmonary airway malformation (CPAM) is a group of rare congenital malformations of the lung and airways. Lung ultrasound (LU) is increasingly used to diagnose neonatal respiratory diseases since it is quick, easy to learn, and radiation-free, but no formal data exist for congenital ...
journal_title:American journal of perinatology
pub_type: 杂志文章,多中心研究
doi:10.1055/s-0038-1645861
更新日期:2018-10-01 00:00:00