Abstract：
:The purpose of this study is to identify obstetrical factors associated with adverse neurological outcome in < or =1000-g infants. In a 1-year (1992-1993) observational study, the NICHD MFMU Network collected obstetrical risk factors for 486 infants who weighed < or =1000 g at birth and who survived > 2 days. Infants' records were abstracted for seizures, intraventricular hemorrhage, and an abnormal neurological evaluation. Seventy-nine (16%) infants had a Grade III or IV intraventricular hemorrhage, 46 (9%) developed seizures and 57 (14%) had an abnormal neurological evaluation. Both lower birth weight and earlier gestational age correlated (P <0.01) with an increasing incidence of all three outcomes. Several other factors appeared to be associated with neurological morbidity, however, after controlling for potential confounders in the multivariate analyses, most of these factors were no longer significant. African-American race, odds ratio (OR) 0.6 (0.3-1.0), and severe preeclampsia, OR 0.2 (0.1-0.7), were protective against intraventricular hemorrhage. Maternal treatment with corticosteroids did not impact neurological outcome in this study population. We conclude that, in a population of < or =1000-g infants, lower birth weight and earlier gestational age were the only consistently significant predictors of all three adverse neurological outcomes.
journal_name
Am J Perinatoljournal_title
American journal of perinatologyauthors
Goepfert AR,Goldenberg RL,Hauth JC,Bottoms SF,Iams JD,Mercer B,MacPherson CA,Moawad AH,VanDorsten JP,Thurnau GRdoi
10.1055/s-2007-993833subject
Has Abstractpub_date
1999-01-01 00:00:00pages
33-42issue
1eissn
0735-1631issn
1098-8785journal_volume
16pub_type
杂志文章abstract：:External cephalic version should be followed by fetal and maternal surveillance until delivery. To shorten this period of surveillance, a protocol of version at term, followed by immediate induction of labor, was adopted. The aim of the present study was to evaluate the effect of this protocol on the subsequent mode o...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-994508
更新日期：1995-11-01 00:00:00
abstract：OBJECTIVE:Our study identified risk factors for the development of clinically identifiable catheter-associated thrombosis (CT). STUDY DESIGN:We performed a retrospective cohort study of neonates in whom a central catheter was present. A total of 1,475 catheters were identified in 766 patients during a 36-month study p...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0038-1667377
更新日期：2019-02-01 00:00:00
abstract：:Novel coronavirus disease 2019 (COVID-19) infection occurring during pregnancy is associated with an increased risk of preterm delivery. This case report describes successful treatment of preterm labor during acute COVID-19 infection. Standard treatment for preterm labor may allow patients with acute COVID-19 infectio...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0040-1709993
更新日期：2020-06-01 00:00:00
abstract：:Disulfiram has been used effectively to deter alcohol consumption in patients with a history of alcohol abuse. Its use in reproductive age women has become increasingly common in recent years, intensifying the risk of fetal exposure. Nonspecific but significant abnormalities have been described in the infants of women...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-994688
更新日期：1993-01-01 00:00:00
abstract：:Managing preterm rupture of membranes (PPROM) is a balance between benefits of prolonging gestation and the risks of perinatal infection. This study evaluates a real-time polymerase chain reaction (PCR) for the detection of amniotic fluid infection and neonatal complications by amniocentesis following PPROM. A total o...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0030-1271212
更新日期：2011-08-01 00:00:00
abstract：OBJECTIVE: Previous analyses of neonatal intensive care units (NICU) antimicrobial stewardship programs have identified key contributors to overall antibiotic use, including prolonged empiric therapy >48 hours for early-onset sepsis (EOS). However, most were performed in mixed NICU settings with onsite birthing units, ...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0040-1722600
更新日期：2021-01-17 00:00:00
abstract：OBJECTIVE:To develop a model to predict cesarean-associated red blood cell transfusion. STUDY DESIGN:Secondary analysis of all cesarean deliveries in the Maternal-Fetal Medicine Units Network Cesarean Registry. Using a split-sample technique, the derivation group was used to identify associated factors and build predi...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0039-1678604
更新日期：2019-07-01 00:00:00
abstract：OBJECTIVE:To evaluate to what extent indicators of placenta insufficiency are associated with low concentrations of insulin-like growth factor 1 (IGF-1) and IGF-1-binding protein-1 (IGFBP-1) in neonatal blood, and to what extent the concentrations of these growth factors are associated with concentrations of proteins w...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0038-1677472
更新日期：2019-12-01 00:00:00
abstract：:We determined the glycemic response to intravenous lipid infusion alone, lipid with amino acids, or amino acids alone in 15 very small premature infants receiving constant glucose infusion during early life. Infants who received lipid or lipid and amino acids demonstrated significant increases in glucose compared with...
journal_title：American journal of perinatology
pub_type： 临床试验,杂志文章
doi：10.1055/s-2007-999685
更新日期：1988-07-01 00:00:00
abstract：:The purpose of this study was to examine factors that were associated with uterine rupture in patients attempting vaginal birth after cesarean delivery. We analyzed the results of all patients attempting vaginal birth after cesarean delivery between September 1996 to December 1999 at a single institution using a conte...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2004-828608
更新日期：2004-05-01 00:00:00
abstract：:There is increasing concern about Chlamydia trachomatis infection during pregnancy, because of reports of increased maternal, fetal, and neonatal risks. Amniotic fluid is known to possess antibacterial activity and has recently been shown to inhibit formation of chlamydial inclusions in McCoy cell culture. To further ...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-999341
更新日期：1991-01-01 00:00:00
abstract：:Objective To determine if mandatory online training in electronic fetal monitoring (EFM) improved agreement in documentation between obstetric care providers and nurses on labor and delivery. Methods Health care professionals working in obstetrics at our institution were required to complete a course on EFM interpreta...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0036-1572540
更新日期：2016-07-01 00:00:00
abstract：:Myocardial infarction in association with pregnancy in patients with the antiphospholipid syndrome has been reported once previously. Our patient, a 22-year-old multiparous woman, experienced a myocardial infarction in the postpartum period. She fulfilled the criteria for the diagnosis of the antiphospholipid syndrome...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-994522
更新日期：1994-01-01 00:00:00
abstract：:We sought to identify maternal or clinical characteristics of women likely to develop preterm labor (PTL) at <34 weeks' gestation while receiving 17 alpha-hydroxyprogesterone caproate (17P) prophylaxis. Current singleton gestations with prior preterm delivery enrolled for outpatient 17P administration at <27 weeks' ge...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0029-1243306
更新日期：2010-04-01 00:00:00
abstract：:A 27-year-old primigravida women was referred for ultrasound studies at 32 weeks' gestation because of the suspicion of fetal ventriculomegaly. Sonographic examination of the fetal brain found a marked shift of the midline, with enlarged left hemisphere and ipsilateral occipital horn, and abnormal convolutions. A 3500...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-999330
更新日期：1991-01-01 00:00:00
abstract：:We report the sixth pregnancy and the first occurrence of twins after liver transplantation, and the second time cyclosporine was used in pregnancy for that indication. The pregnancy was interrupted at 33 weeks, menstrual age, for exacerbation of chronic graft rejection and intrauterine growth retardation of both twin...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-999362
更新日期：1991-03-01 00:00:00
abstract：OBJECTIVE:This study aims to determine risk factors for rehospitalization in extremely premature infants. STUDY DESIGN:A retrospective cohort study of 157 infants born < 29 weeks' gestational age assessing risk factors for rehospitalization through 2 years of life. RESULTS:Multivariable logistic regression showed tha...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0035-1555123
更新日期：2016-01-01 00:00:00
abstract：OBJECTIVE:We aimed to compare the rates of "surfactant treated respiratory disease" and other neonatal morbidities among moderately preterm (MPT) infants exposed to no, partial, or a complete course of antenatal corticosteroids (ANS). STUDY DESIGN:This observational cohort study evaluated MPT infants (290/7-336/7 week...
journal_title：American journal of perinatology
pub_type： 杂志文章,多中心研究
doi：10.1055/s-0038-1642059
更新日期：2018-10-01 00:00:00
abstract：:The objective of this study was to evaluate the diagnostic accuracy of different single ultrasonographic parameters in predicting intrauterine growth-restricted (IUGR) babies as defined by Ponderal index at birth. Study sample composed of two sets of data from Iran and Australia. The Iranian sample consisted of 296 Ir...
journal_title：American journal of perinatology
pub_type： 杂志文章,多中心研究
doi：10.1055/s-2001-17856
更新日期：2001-09-01 00:00:00
abstract：:Antihistamines are commonly used to treat nausea and vomiting of pregnancy (NVP). We re-analyzed the 24 primary studies cited in a 1997 meta-analysis that concluded antihistamine use for NVP was safe as they had been studied in more than 200,000 participating women and the pooled odds ratio for congenital malformation...
journal_title：American journal of perinatology
pub_type： 杂志文章,meta分析
doi：10.1055/s-0033-1358772
更新日期：2014-09-01 00:00:00
abstract：OBJECTIVE:To evaluate the association between adequacy of prenatal care utilization and risk of fetal and neonatal mortality and adverse outcomes. METHODS:We conducted a population-based cohort study using the Center for Disease Control and Prevention's Linked Birth-Infant Death and Fetal Death data on all deliveries ...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0032-1316439
更新日期：2012-11-01 00:00:00
abstract：:Anti-Cw is an uncommon cause of clinically significant hemolytic disease of the newborn (HDN). We report an unusually severe case of HDN due to anti-Cw that required phototherapy and exchange transfusion. We also describe a novel PCR-RFLP method for Cw typing of fetal genomic DNA that was used for prenatal diagnosis i...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-993872
更新日期：1999-01-01 00:00:00
abstract：OBJECTIVE: To determine the association between total gestational weight gain and perinatal outcomes. STUDY DESIGN: Data from the Nulliparous Pregnancy Outcomes Study: Monitoring Mothers-To-Be (NuMoM2b) study were used. Total gestational weight gain was categorized as inadequate, adequate, or excessive based on the 20...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0039-1696640
更新日期：2021-01-01 00:00:00
abstract：:The aim of this prospective study was to investigate, using echocardiography, the relationship between heart murmurs found in the neonatal period and atrial septal defect (ASD). Heart murmurs were detected in 115 of 5124 term neonates within 1 month after birth. The babies were followed by echocardiographic examinatio...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2003-40609
更新日期：2003-05-01 00:00:00
abstract：OBJECTIVE: American College of Cardiology and American Heart Association (ACC/AHA) published new guidelines which lower the cut-off for hypertension. We sought to evaluate the impact of these guidelines to cost and benefit of various low-dose aspirin prophylaxis approaches. STUDY DESIGN: Decision tree analysis was cre...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0039-1697588
更新日期：2019-10-11 00:00:00
abstract：:Exposure to immunosuppressant agents during gestation can affect the fetal immune system. The aim of this study was to evaluate the immune function of infants whose mothers were administered immunosuppressants during pregnancy for the treatment of autoimmune disorders. Circulating lymphocyte subsets and in vitro immun...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-986679
更新日期：2007-09-01 00:00:00
abstract：OBJECTIVE: Potentially avoidable maternity complications (PAMCs) have been validated as an indicator of access to quality prenatal care. African-American mothers have exhibited a higher incidence of PAMCs, which has been attributed to unequal health coverage. The objective of this study was to assess if racial disparit...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0040-1701195
更新日期：2020-01-27 00:00:00
abstract：OBJECTIVE:To determine epidemiology and clinical characteristics of infants with methicillin-susceptible (MSSA) and -resistant Staphylococcus aureus (MRSA) in a level III neonatal intensive care unit (NICU). STUDY DESIGN:All NICU admissions (2001 to 2008) with any positive S. aureus culture were included as cases. Cas...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0032-1304819
更新日期：2012-06-01 00:00:00
abstract：OBJECTIVE:To evaluate whether tocolysis with nifedipine can be omitted in women with symptoms of preterm labor, a shortened cervix, and negative fetal fibronectin test. STUDY DESIGN:A randomized noninferiority trial was performed in all Dutch perinatal centers. Women with symptoms of preterm labor between 24 and 34 we...
journal_title：American journal of perinatology
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1055/s-0034-1390346
更新日期：2015-04-01 00:00:00
abstract：:This study was conducted to examine the potential effects of expanded Medicaid coverage for low income women. Statewide birth data for 1983 to 1985 were examined to determine the relationship between prenatal care and admissions to neonatal intensive care units (NICUs) and the costs of this care. An NICU sample was co...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-994790
更新日期：1992-07-01 00:00:00
