Risk Factors Linked to Central Catheter-Associated Thrombosis in Critically Ill Infants in the Neonatal Intensive Care Unit.

Abstract:

OBJECTIVE:Our study identified risk factors for the development of clinically identifiable catheter-associated thrombosis (CT). STUDY DESIGN:We performed a retrospective cohort study of neonates in whom a central catheter was present. A total of 1,475 catheters were identified in 766 patients during a 36-month study period. The odds ratio (OR) of thrombi formation in catheterized neonates was modeled using simple (single predictor) and multiple (multiple predictors) logistic regressions as well as simple and multiple Cox's proportional hazard models. RESULT:The incidence of CT was 1.17 per 100 neonates. Unadjusted factors including age at insertion, history of surgery before or during line placement, cholestasis, femoral location, and line size significantly increased the OR or hazards ratio (HR) of developing thrombi formation. In multiple logistic and Cox's regression analyses, three factors continued to be significantly associated with OR or HR of thrombi formation: line size, femoral location, and cholestasis. CONCLUSION:We conclude that clinically identifiable CT is rare in the neonatal population. Furthermore, catheter-specific characteristics are predictive for CT and require further investigation.

journal_name

Am J Perinatol

authors

Lambert I,Tarima S,Uhing M,Cohen SS

doi

10.1055/s-0038-1667377

subject

Has Abstract

pub_date

2019-02-01 00:00:00

pages

291-295

issue

3

eissn

0735-1631

issn

1098-8785

journal_volume

36

pub_type

杂志文章
  • Accurate gestational dating: revisited.

    abstract::Using first trimester fetal crown-rump length (CRL) measurements as the criterion for gestational dating, rather than menstrual history or neonatal gestational age evaluation after birth, may be a more accurate way of evaluating the accuracy of second or third trimester ultrasonic measurements for gestational age esti...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-2007-994606

    authors: Ott WJ

    更新日期:1994-11-01 00:00:00

  • Noninvasive High-Frequency Oscillatory Ventilation: A Retrospective Chart Review.

    abstract:OBJECTIVE: This study aimed to review the feasibility of nasal high-frequency oscillatory ventilation (NHFOV) in preventing reintubation in preterm infants STUDY DESIGN:  This is a retrospective cohort study of all premature newborn infants placed on NHFOV in a single-center neonatal intensive care unit. RESULTS: Twen...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-0040-1718738

    authors: Ali YAH,Seshia MM,Ali E,Alvaro R

    更新日期:2020-10-19 00:00:00

  • Hypophosphatemia is Prevalent among Preterm Infants Less than 1,500 Grams.

    abstract:OBJECTIVE:This article identifies the prevalence and associated factors of hypophosphatemia (HP) in very low birth weight (VLBW) infants in the first week of life. STUDY DESIGN:Prospective exploratory cohort study of 106 consecutive VLBW infants admitted to neonatal intensive care at Foothills Hospital, Calgary, Canad...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-0039-1677713

    authors: Al-Wassia H,Lyon AW,Rose SM,Sauve RS,Fenton TR

    更新日期:2019-11-01 00:00:00

  • The Acylcarnitine Profile in Dried Blood Spots is Affected by Hematocrit: A Study of Newborn Screening Samples in Very-Low-Birth-Weight Infants.

    abstract:OBJECTIVE: The acylcarnitine profile is analyzed in dried blood spots (DBS) to screen for inborn errors of metabolism. Hematocrit (Ht) is known to affect the result of quantitative analyses of DBS samples; however, the effects of Ht on the acylcarnitine profiles in DBS have not been studied in actual samples from newbo...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-0040-1721849

    authors: Haga M,Isobe M,Kawabata K,Shimizu M,Mochizuki H

    更新日期:2020-12-29 00:00:00

  • The significance of antiphospholipid antibodies in pregnant women with chronic hypertension.

    abstract::The objective of this study was to perform antiphospholipid antibody screening in women with chronic hypertension to assess whether the presence of such antibodies is associated with adverse pregnancy outcome. Serum for anticardiolipin antibodies and lupus anticoagulant was obtained in pregnant women with chronic hype...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-2004-829870

    authors: Zeeman GG,Alexander JM,McIntire DD,Leveno KJ

    更新日期:2004-07-01 00:00:00

  • Prevalence of Sonographic Markers of Placenta Accreta Spectrum in Low-Risk Pregnancies.

    abstract:OBJECTIVE:This study was aimed to evaluate the prevalence of sonographic markers for placenta accreta spectrum (PAS) in pregnancies at low-risk for PAS. STUDY DESIGN:Pregnant women at low-risk for PAS presenting for routine second trimester ultrasound who enrolled in the study were evaluated prospectively for sonograp...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-0038-1676488

    authors: Philips J,Gurganus M,DeShields S,Cunningham T,Sinkovskaya E,Kanaan C,Porche L,Abuhamad A

    更新日期:2019-07-01 00:00:00

  • Endocrine Disruptors: A Potential Risk Factor for Gestational Diabetes Mellitus.

    abstract::Gestational diabetes mellitus (GDM) has increased dramatically in the past 20 years together with the obesity epidemic. Mirroring the increase in incidence of GDM is increasing use of endocrine disrupting chemicals (EDCs). EDCs are structurally similar to endogenous hormones and interfere with synthesis, secretion, ac...

    journal_title:American journal of perinatology

    pub_type: 杂志文章,评审

    doi:10.1055/s-0036-1586500

    authors: Ehrlich S,Lambers D,Baccarelli A,Khoury J,Macaluso M,Ho SM

    更新日期:2016-11-01 00:00:00

  • Third trimester ultrasonic presentation of infantile polycystic kidney disease.

    abstract::Infantile polycystic kidney disease (Potter's Type 1) is an autosomal recessive disorder that affects the kidneys and liver. Use of ultrasound to make the diagnosis prenatally is well documented and, in fact, it is advocated as a screening device for second-trimester identification of potentially affected fetuses. The...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-2007-999726

    authors: Argubright KF,Wicks JD

    更新日期:1987-01-01 00:00:00

  • Intravenous lipid and amino acids briskly increase plasma glucose concentrations in small premature infants.

    abstract::We determined the glycemic response to intravenous lipid infusion alone, lipid with amino acids, or amino acids alone in 15 very small premature infants receiving constant glucose infusion during early life. Infants who received lipid or lipid and amino acids demonstrated significant increases in glucose compared with...

    journal_title:American journal of perinatology

    pub_type: 临床试验,杂志文章

    doi:10.1055/s-2007-999685

    authors: Savich RD,Finley SL,Ogata ES

    更新日期:1988-07-01 00:00:00

  • First-trimester transvaginal ultrasonographic diagnosis of Dandy-Walker malformation.

    abstract::We present transvaginal ultrasonographic findings of a fetus with Dandy-Walker malformation and associated massive obstructive hydrocephalus at 13 weeks' gestation. First-trimester ultrasonographic diagnosis of Dandy-Walker malformation is uncommon with only two such occurrences having been reported previously. These ...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-2001-18697

    authors: Sherer DM,Shane H,Anyane-Yeboa K

    更新日期:2001-11-01 00:00:00

  • Aplasia cutis congenita in an infant of an initial triplet gestation: a case report.

    abstract::Aplasia cutis congenita (ACC) is the clinical manifestation of an uncommon group of skin disorders. One postulated etiology is disseminated intravascular coagulation from release of thrombogenic maternal arising from placental injury or fetal demise. This leads to disruption of the ectodermal blood supply responsible ...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-1999-7279

    authors: Da-Silva SS,Fagbongbe EO

    更新日期:1999-01-01 00:00:00

  • Necrotizing enterocolitis in a premature infant as the presenting symptom of familial dysautonomia in the neonatal period: case report and review of the literature.

    abstract::We present a case of a premature infant with early-onset necrotizing enterocolitis as the presenting symptom of familial dysautonomia. The diagnosis of familial dysautonomia in the neonatal period is usually rare and difficult, because many of the symptoms may be mild or nonspecific, whereas other characteristic signs...

    journal_title:American journal of perinatology

    pub_type: 杂志文章,评审

    doi:10.1055/s-2005-871525

    authors: Barak S,Riskin A,Kugelman A,Abend-Weinger M,Chistyakov I,Bader D

    更新日期:2005-10-01 00:00:00

  • Cardiovascular Associations with Abnormal Brain Magnetic Resonance Imaging in Neonates with Hypoxic Ischemic Encephalopathy Undergoing Therapeutic Hypothermia and Rewarming.

    abstract:OBJECTIVE:This article compares hemodynamic characteristics of neonates with hypoxic ischemic encephalopathy (HIE) receiving therapeutic hypothermia (TH) with normal versus abnormal brain magnetic resonance imaging (MRI). METHODS:Serial echocardiography (echo) was performed within 24 hours, after 48 to 72 hours of coo...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-0038-1629900

    authors: More KS,Sakhuja P,Giesinger RE,Ting JY,Keyzers M,Sheth JN,Lapointe A,Jain A,Moore AM,Miller SP,McNamara PJ

    更新日期:2018-08-01 00:00:00

  • Midpregnancy Cervical Length in Nulliparous Women and its Association with Postterm Delivery and Intrapartum Cesarean Delivery.

    abstract:OBJECTIVE:To evaluate the association between midpregnancy cervical length and postterm delivery and cesarean delivery during labor. STUDY DESIGN:In a multicenter cohort study, cervical length was measured in low-risk singleton pregnancies between 16 and 22 weeks of gestation. From this cohort, we identified nulliparo...

    journal_title:American journal of perinatology

    pub_type: 杂志文章,多中心研究

    doi:10.1055/s-0035-1556067

    authors: van der Ven AJ,van Os MA,Kleinrouweler CE,Verhoeven CJ,de Miranda E,Bossuyt PM,de Groot CJ,Haak MC,Pajkrt E,Mol BW,Kazemier BM

    更新日期:2016-01-01 00:00:00

  • Prolactin and plasma prostaglandin metabolite levels in patients undergoing nipple stimulation contraction stress tests.

    abstract::Twenty-five patients undergoing nipple stimulation contraction stress tests were enrolled in this study. Plasma 13,14-dihydro, 15-keto prostaglandin F2 alpha and plasma prolactin concentrations were analyzed before and during the contraction stress tests. Prolactin concentrations were significantly higher (p less than...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-2007-999444

    authors: Rijhsinghani AG,Dubin NH,Zacur HA,Johnson TR,Niebyl JR

    更新日期:1990-01-01 00:00:00

  • Lung Ultrasound Findings in Congenital Pulmonary Airway Malformation.

    abstract:BACKGROUND AND OBJECTIVE:Congenital pulmonary airway malformation (CPAM) is a group of rare congenital malformations of the lung and airways. Lung ultrasound (LU) is increasingly used to diagnose neonatal respiratory diseases since it is quick, easy to learn, and radiation-free, but no formal data exist for congenital ...

    journal_title:American journal of perinatology

    pub_type: 杂志文章,多中心研究

    doi:10.1055/s-0038-1645861

    authors: Yousef N,Mokhtari M,Durand P,Raimondi F,Migliaro F,Letourneau A,Tissières P,De Luca D

    更新日期:2018-10-01 00:00:00

  • Inadvertent amniocenteses occurring during unrelated invasive diagnostic procedures in the third trimester.

    abstract::Two cases of inadvertent third trimester amniocenteses occurring during attempted spinal tap and culdocentesis are presented. These hitherto undescribed occurrences stress potential complications of these invasive diagnostic procedures in the gravid woman. ...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-2007-994618

    authors: Sherer DM,Abramowicz JS

    更新日期:1993-11-01 00:00:00

  • Extreme morbid obesity and labor outcome in nulliparous women at term.

    abstract::We examined the prevalence of cesarean delivery (CD) among women with morbid obesity and extreme morbid obesity. Using Kentucky birth certificate data, a cross-sectional analysis of nulliparous singleton gestations at term was performed. We examined the prevalence of CD by body mass index (BMI; in kg/m2) using the Nat...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-0031-1280852

    authors: Garabedian MJ,Williams CM,Pearce CF,Lain KY,Hansen WF

    更新日期:2011-10-01 00:00:00

  • Evaluation of a universal real-time polymerase chain reaction for detection of amniotic fluid infection in premature rupture of membranes.

    abstract::Managing preterm rupture of membranes (PPROM) is a balance between benefits of prolonging gestation and the risks of perinatal infection. This study evaluates a real-time polymerase chain reaction (PCR) for the detection of amniotic fluid infection and neonatal complications by amniocentesis following PPROM. A total o...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-0030-1271212

    authors: Debiève F,Ska S,Williams O,Hutchings G,Bernard P,Grandjean P,Hubinont C

    更新日期:2011-08-01 00:00:00

  • Predicting perinatal mortality in preterm intrauterine growth restriction.

    abstract::We evaluated if maternal demographic and ultrasound parameters predict perinatal mortality in preterm intrauterine growth restriction (IUGR). Retrospective cohort study of preterm IUGR (delivery gestational age <35 weeks and birth weight <10th percentile for gestation). We excluded twins and fetuses with aneuploidy, i...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-0029-1223284

    authors: Scifres CM,Stamilio D,Macones GA,Odibo AO

    更新日期:2009-11-01 00:00:00

  • Developmental aspects of percutaneous caffeine absorption in premature infants.

    abstract::Caffeine is commonly used in the treatment of apnea of prematurity. The skin of preterm infants varies considerably in its level of maturity. To understand skin absorption in low birthweight infants (less than 1500 gm) with gestational age between 26 and 34 weeks, a group of 56 preterm babies was studied after percuta...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-2007-999282

    authors: Amato M,Hüppi P,Isenschmid M,Schneider H

    更新日期:1992-09-01 00:00:00

  • Bleeding Complications and Mortality in Neonates Receiving Therapeutic Hypothermia and Extracorporeal Membrane Oxygenation.

    abstract:OBJECTIVE: The objective of this study was to compare complications and mortality in neonates with hypoxic ischemic encephalopathy (HIE) on extracorporeal membrane oxygenation (ECMO) who did and did not receive therapeutic hypothermia (TH). STUDY DESIGN: The Extracorporeal Life Support Organization registry was querie...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-0037-1607197

    authors: Cuevas Guaman M,Lucke AM,Hagan JL,Kaiser JR

    更新日期:2018-02-01 00:00:00

  • Pregnancy and warm autoantibodies: a case report.

    abstract::The presence of the maternal warm antibody in pregnancy should not be ignored. As there is risk of both maternal and fetal anemia, both patients need to be followed for the development of such. Serial complete blood counts in the mother and treatment if significant fetal anemia develops should be considered. Serial am...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-2007-994196

    authors: Gerson A,Young L,Ferroni J,Russino J,Sidor C,Cooper J,Herman J

    更新日期:1996-01-01 00:00:00

  • Remifentanil analgesia during laser treatment for retinopathy of prematurity: a practical approach in neonatal intensive care unit.

    abstract:BACKGROUND:Retinopathy of prematurity (ROP) is a significant cause of childhood blindness. AIM:The aim of this study is to determine the feasibility of remifentanil analgesia during laser treatment of ROP performed in the neonatal intensive care unit (NICU). PATIENTS AND METHODS:Remifentanil was infused continuously ...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-0034-1370348

    authors: Demirel N,Bas AY,Kavurt S,Celik IH,Yucel H,Turkbay D,Hekimoğlu E,Koc O

    更新日期:2014-11-01 00:00:00

  • Postpartum myocardial infarction in a patient with antiphospholipid syndrome.

    abstract::Myocardial infarction in association with pregnancy in patients with the antiphospholipid syndrome has been reported once previously. Our patient, a 22-year-old multiparous woman, experienced a myocardial infarction in the postpartum period. She fulfilled the criteria for the diagnosis of the antiphospholipid syndrome...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-2007-994522

    authors: Thorp JM Jr,Chescheir NC,Fann B

    更新日期:1994-01-01 00:00:00

  • The surfactants.

    abstract::Surfactants have been routinely used since 1990 for the treatment of respiratory distress syndrome (RDS). The use of surfactant has coincided with a decrease in mortality in infants due to RDS. This review focuses on clinical aspects of surfactant use. New information, particularly effects of ventilatory styles on sur...

    journal_title:American journal of perinatology

    pub_type: 杂志文章,评审

    doi:10.1055/s-2000-13445

    authors: Kallapur S,Ikegami M

    更新日期:2000-01-01 00:00:00

  • Optimum click rate for neurodevelopmental evaluation using auditory brainstem response in premature infants.

    abstract:OBJECTIVE:To determine the optimal click rate (CR) for neurodevelopmental assessment using auditory brainstem evoked response (ABR) in preterm infants. STUDY DESIGN:A prospective study was performed in 17 preterm infants at 34 weeks' postmenstrual age. Three separate ABRs were performed a few minutes apart on each sub...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-0032-1311982

    authors: Amin SB,Orlando M

    更新日期:2012-09-01 00:00:00

  • Fetal liver biopsy for prenatal diagnosis of carbamoyl phosphate synthetase deficiency.

    abstract::Carbamoyl phosphate synthetase deficiency is a type of an inborn error of metabolism with a poor prognosis. Carbamoyl phosphate synthetase is a liver-specific enzyme, and its deficiency can only be diagnosed by enzyme assay using liver biopsy specimens. A pregnant woman at risk for carbamoyl phosphate synthetase defic...

    journal_title:American journal of perinatology

    pub_type: 杂志文章,评审

    doi:10.1055/s-2007-994579

    authors: Murotsuki J,Uehara S,Okamura K,Yajima A,Oura T,Miyabayashi S

    更新日期:1994-03-01 00:00:00

  • Nonimmune hydrops fetalis due to congenital syphilis associated with negative intrapartum maternal serology screening.

    abstract::We present an unusual case, in which a woman presenting with markedly decreased fetal movements at 29 weeks gestation following a recent increase in fundal height was noted sonographically to have fetal hydrops consisting of scalp edema, marked hepatomegaly, ascites, and polyhydramnios. No lethal structural congenital...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-2007-993933

    authors: Levine Z,Sherer DM,Jacobs A,Rotenberg O

    更新日期:1998-04-01 00:00:00

  • Serum unconjugated estriols in insulin-dependent diabetic pregnancies: normative data and clinical relevance.

    abstract::The purpose of this study was to establish normative reference values for serum unconjugated estriol (E3) concentrations in insulin-dependent diabetic pregnancy. There were 1973 samples analyzed in 63 diabetic pregnancies not complicated by fetal distress and/or neonatal asphyxia. These samples were compared with 867 ...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-2007-999718

    authors: Miodovnik M,Mimouni F,Hertzberg VS,Siddiqi TA,Tsang RC

    更新日期:1988-10-01 00:00:00