Abstract:
:We present a case of a premature infant with early-onset necrotizing enterocolitis as the presenting symptom of familial dysautonomia. The diagnosis of familial dysautonomia in the neonatal period is usually rare and difficult, because many of the symptoms may be mild or nonspecific, whereas other characteristic signs and symptoms appear only later in life. The neonatologist should be aware of this rare diagnosis in the neonatal period, especially in the offspring of Ashkenazi Jews. The diagnosis is genetic. Preconception counseling to future parents belonging to populations at risk should include recommendation for genetic screening test to identify carriers of the mutations in the familial dysautonomia gene.
journal_name
Am J Perinatoljournal_title
American journal of perinatologyauthors
Barak S,Riskin A,Kugelman A,Abend-Weinger M,Chistyakov I,Bader Ddoi
10.1055/s-2005-871525subject
Has Abstractpub_date
2005-10-01 00:00:00pages
353-5issue
7eissn
0735-1631issn
1098-8785journal_volume
22pub_type
杂志文章,评审abstract::Persistent fetal bradycardia is rarely encountered during pregnancy. When it is associated with a complete atrio-ventricular (A-V) block, it may prove dangerous to the fetus or newborn. The prenatal diagnosis is vital because it necessitates close follow-up during pregnancy to detect fetal compromise and proper prepar...
journal_title:American journal of perinatology
pub_type: 杂志文章,评审
doi:10.1055/s-2007-994152
更新日期:1997-07-01 00:00:00
abstract::Premature closure of the foramen ovale is a rare cardiac anomaly. Severe right-sided heart failure accounts for the hepatomegaly, ascites, pleural and pericardial effusions, and generalized edema of these hydropic fetuses. Premature closure of the foramen ovale should be a part of the differential diagnosis when unexp...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-994616
更新日期:1994-11-01 00:00:00
abstract:OBJECTIVE: The aim of the study is to model amplitude-integrated electroencephalography (aEEG) utility to diagnose seizures in common clinical scenarios. STUDY DESIGN: Using reported neonatal seizure prevalence and aEEG sensitivities and specificities, likelihood ratios (LRs) and post-test probabilities were calculate...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0040-1721711
更新日期:2020-12-15 00:00:00
abstract::Primary genital herpes simplex virus (HSV) infection in pregnancy is associated with an increased risk of vertical transmission to the fetus, especially with rupture of membranes. Two cases of primary herpes and two cases of recurrent herpes in pregnancy with preterm premature rupture of membranes and expectant manage...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2002-33090
更新日期:2002-07-01 00:00:00
abstract::Introduction First-trimester ultrasound (US) for anatomy assessment may improve anomaly detection, but it may also increase overall US utilization. We sought to assess the utility of first-trimester US for evaluation of fetal anatomy. Materials and Methods A decision analytic model was created to compare first- plus s...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0036-1579652
更新日期:2016-08-01 00:00:00
abstract:OBJECTIVE:To evaluate the interobserver reliability of fetal heart rate (FHR) pattern definition and interpretation assessed by physicians at various levels of training using standard Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) definitions and standard principles of interpret...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0032-1326991
更新日期:2013-06-01 00:00:00
abstract:OBJECTIVE:To determine if preincubation with prostaglandin E1 (PGE1) and E2 (PGE2) enhances oxytocin-induced myometrial contractility in vitro. STUDY DESIGN:Myometrial strips from 13 women were incubated with PGE1 (10-5 mol/L or 10-6 mol/L), PGE2 (10-5 mol/L or 10-6 mol/L) or solvent before adding cumulative concentra...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0032-1329696
更新日期:2013-09-01 00:00:00
abstract:OBJECTIVE: This study was aimed to describe continuous labor curves, including second stage, based on fetal head station. STUDY DESIGN: We performed a prospective multicenter cohort study. The inclusion criteria were women with singleton uncomplicated cephalic term pregnancies in labor, who delivered vaginally. We use...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0040-1702989
更新日期:2020-03-02 00:00:00
abstract:OBJECTIVE:We have previously shown a decrease in the overall stillbirth rate at our institution in women receiving the seasonal influenza vaccine during pregnancy. The goal of this study was to ascertain factors associated with this decrease. STUDY DESIGN:This was a retrospective cohort study examining the stillbirth ...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0034-1544046
更新日期:2015-05-01 00:00:00
abstract::Aplasia cutis congenita (ACC) is the clinical manifestation of an uncommon group of skin disorders. One postulated etiology is disseminated intravascular coagulation from release of thrombogenic maternal arising from placental injury or fetal demise. This leads to disruption of the ectodermal blood supply responsible ...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-1999-7279
更新日期:1999-01-01 00:00:00
abstract::Diagnostic ultrasonography has given us the opportunity to diagnose several congenital malformations in utero. Skeletal dysplasias is a heterogeneous group of disorders of the skeleton. Although disorders of bone growth are often diagnosed in utero, it is usually a general diagnosis because the exact syndrome cannot b...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-994638
更新日期:1993-03-01 00:00:00
abstract::Mixoploidy is rare chromosomal disorder characterized by multiple cell lines, usually including triploidy, within tissues. Pregnancy outcome has generally been considered poor with congenital anomalies and developmental delay reported in postnatally diagnosed cases. We report on two cases of abnormal midtrimester ultr...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0030-1249361
更新日期:2010-09-01 00:00:00
abstract::The manifestations of fetal varicella syndrome usually involve several organ systems, including skin, ocular, neurologic, gastrointestinal, and genitourinary. Although ocular anomalies have been reported to be as high as 68%, manifestations limited to the eyes is extremely rare. Herein we report the case of fetal vari...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-994493
更新日期:1995-09-01 00:00:00
abstract::Care of women with preterm labor has been reported by Katz et al to be enhanced by use of an electronic uterine contraction monitor. We enrolled 76 women with singleton gestations who had been successfully treated for preterm labor into a prospective randomized trial, assigning subjects in a ratio of 1:2 to a group of...
journal_title:American journal of perinatology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1055/s-2007-999473
更新日期:1990-04-01 00:00:00
abstract::Managing preterm rupture of membranes (PPROM) is a balance between benefits of prolonging gestation and the risks of perinatal infection. This study evaluates a real-time polymerase chain reaction (PCR) for the detection of amniotic fluid infection and neonatal complications by amniocentesis following PPROM. A total o...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0030-1271212
更新日期:2011-08-01 00:00:00
abstract::We sought to validate center-specific published medians and estimate the effects of sonologist and Doppler measurement techniques on middle cerebral artery (MCA) peak systolic velocity (PSV) values. We studied 154 gravidas with normal singletons who underwent MCA PSV measurement at 18 to 35 weeks' gestation by one of ...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0030-1249365
更新日期:2010-09-01 00:00:00
abstract::The objective of this study was to identify the most efficient and cost-effective nebulizer device for delivery of albuterol aerosol as a bronchodilator in ventilated preterm infants. Bronchodilators are frequently used as part of the therapeutic regimen of ventilated preterm infants. This can be delivered by differen...
journal_title:American journal of perinatology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1055/s-2001-14526
更新日期:2001-05-01 00:00:00
abstract::The ultrastructural architecture of colostral cells of mothers of pre- and full-term infants is described. The polymorphonuclears were engaged in vivid phagocytosis of fat droplets. Similar findings were observed on the macrophages. The lymphocytes appeared normal in size and ultrastructure. A small number of eosinoph...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-994162
更新日期:1997-07-01 00:00:00
abstract::Hypertensive disorders during pregnancy implicate placental pathologic conditions, which may interfere with the normal passage of alpha-fetoprotein (AFP) to the maternal blood. We compared the levels of maternal serum (MS) in early second trimester of pregnancies complicated by hypertensive disorders with those of mat...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-999254
更新日期:1992-09-01 00:00:00
abstract::The concentration of myometrial and decidual oxytocin receptors increases dramatically in normal women in late pregnancy, causing enhanced uterine sensitivity to physiologic levels of oxytocin. Similar increase in myometrial oxytocin receptors has been found in women in preterm labor, indicating a role for oxytocin al...
journal_title:American journal of perinatology
pub_type: 临床试验,杂志文章
doi:10.1055/s-2007-999575
更新日期:1989-04-01 00:00:00
abstract::Intra-amniotic infection is often the cause of a second-trimester abortion. The bacterial species involved include bacteria with low pathogenicity like Ureaplasma urealyticum and various Mycoplasma species. In this case we describe an intra-amniotic infection caused by Capnocytophaga sputigena, often found in the norm...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-993854
更新日期:1999-01-01 00:00:00
abstract::There were 107 episodes of pyelonephritis associated with pregnancy or the early puerperium occurring in 103 gravidas investigated retrospectively for information concerning prematurity, low birthweight, and antibiotic susceptibility patterns in the recovered microorganisms. No difference was found in the incidence of...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-999800
更新日期:1987-10-01 00:00:00
abstract::In Finland a nationwide free prenatal care system was mandated by law in 1944. At present, 99.9% of Finland's pregnant women use it. The primary aim is to provide advice and care to all women in local centers and to identify pregnant women exhibiting risk factors and refer them to specialized prenatal units located in...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-999581
更新日期:1989-04-01 00:00:00
abstract::Rotavirus is the most common nonseasonal vaccine preventable illness. Despite increased severity of rotaviral illness in early infancy, most neonatal intensive care units (NICU) do not administer rotavirus vaccination either during the NICU stay at age of eligibility or at discharge as the Advisory Committee on Immuni...
journal_title:American journal of perinatology
pub_type: 杂志文章,评审
doi:10.1055/s-0038-1660463
更新日期:2018-12-01 00:00:00
abstract::Although mother's milk is the optimal nutrition for preterm infants, the amount of protein, calcium, and phosphorus become inadequate for the growth of preterm infants, such that fortification is recommended when enteral feeding is established. Recently, intestinal obstruction due to calcium soap formation has been re...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0031-1295659
更新日期:2012-04-01 00:00:00
abstract:OBJECTIVE: Semiquantitative lung ultrasound improves the timeliness of surfactant replacement, but its financial consequences are unknown. We aim to investigate if the ultrasound-guided surfactant administration influences the general costs of surfactant therapy for preterm neonates affected by respiratory distress syn...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0040-1715821
更新日期:2020-08-20 00:00:00
abstract::We present an unusual case of a primigravida with a viable cervical pregnancy diagnosed by transvaginal ultrasound and magnetic resonance imaging. Staggered conservative therapeutic measures included systemic high-dose Methotrexate with Folinic acid rescue followed by bilateral embolization of the uterine arteries in ...
journal_title:American journal of perinatology
pub_type: 杂志文章,评审
doi:10.1055/s-2003-42341
更新日期:2003-07-01 00:00:00
abstract:OBJECTIVE:This study aimed to assess the applicability of the insertion of small diameter catheters through the femoral vein in extremely low-birth-weight (ELBW) infants. STUDY DESIGN:All femoral small diameter catheters (Silastic or femoral arterial catheter [FAC]) inserted in ELBW infants in a tertiary level neonata...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0039-1693718
更新日期:2020-12-01 00:00:00
abstract:OBJECTIVE:This study aimed to evaluate temporal trends in opioid use disorder (OUD) during antepartum and postpartum hospitalizations. STUDY DESIGN:This repeated cross-sectional analysis analyzed data from the National (Nationwide) Inpatient Sample. Women aged 15 to 54 years admitted antepartum or postpartum were iden...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0039-1694725
更新日期:2020-12-01 00:00:00
abstract::Limited research in young adults and immature animals suggests a detrimental effect of tobacco on bone during growth. We aimed to determine the adverse effects of maternal nicotine exposure during pregnancy and lactation on neonatal rat bone development, and to determine a protective effect of ascorbic acid. Gravid ra...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2006-951287
更新日期:2006-10-01 00:00:00