Abstract:
OBJECTIVE: Semiquantitative lung ultrasound improves the timeliness of surfactant replacement, but its financial consequences are unknown. We aim to investigate if the ultrasound-guided surfactant administration influences the general costs of surfactant therapy for preterm neonates affected by respiratory distress syndrome. STUDY DESIGN: This is a pharmacoeconomic, retrospective, and before-and-after study investigating the impact of ultrasound-guided surfactant replacement (echography-guided Surfactant THERapy [ESTHER]) on pharmaceutical expenditure within the ESTHER initiative. Data extracted from the institutional official database hosted by the hospital administration for financial management were used for the analysis. We analyzed the number of surfactant administrations in neonates of gestational age ≤326/7 weeks, and the number of surfactant vials used from January 1, 2014 to June 30, 2014 (i.e., during the period of standard surfactant administration policy) and from July 1, 2016 to December 31, 2018 (that is during ESTHER policy). RESULTS: ESTHER did not modify surfactant use, as proportion of treated neonates with RDS receiving at least one surfactant dose (Standard: 21.3% vs. ESTHER: 20.9%; p = 0.876) or as proportion of used vials over the total number of vials opened for neonates of any gestational age (Standard: 37% vs. ESTHER: 35%; p = 0.509). CONCLUSION: Ultrasound-guided surfactant replacement using a semiquantitative lung ultrasound score in preterm infants with RDS does not change the global use of surfactant and the related expenditure. KEY POINTS:· ESTHER is able to increase the timeliness of surfactant replacement.. · The ultrasound-guided surfactant administration does not increase the cost of surfactant therapy.. · The ultrasound-guided surfactant administration does not change the global surfactant utilization..
journal_name
Am J Perinatoljournal_title
American journal of perinatologyauthors
De Luca D,Yousef Ndoi
10.1055/s-0040-1715821subject
Has Abstractpub_date
2020-08-20 00:00:00eissn
0735-1631issn
1098-8785pub_type
杂志文章abstract:OBJECTIVE:To determine if patients with a history of low pregnancy-associated plasma protein A (PAPP-A) in an initial pregnancy are at higher risk for adverse obstetric outcomes in a subsequent pregnancy. STUDY DESIGN:This was a retrospective cohort study in patients who underwent first trimester screening for PAPP-A ...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0038-1673651
更新日期:2019-05-01 00:00:00
abstract:OBJECTIVE: This article aims to compare long-term neurodevelopmental and health outcomes of twins born at 34 weeks or later, based on the presence of small for gestational age (SGA). STUDY DESIGN: This study is a mail-based survey of twin gestations delivered by a single practice. We compared twins with and without SG...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0037-1607043
更新日期:2018-02-01 00:00:00
abstract::We compared perinatal outcomes between live-born nonisolated and isolated omphaloceles diagnosed during a prenatal ultrasound. Fetuses (n = 86) with omphalocele were identified between 1995 and 2007 at a single institution. Inclusion criteria were an omphalocele >14 weeks' gestation, available fetal and/or neonatal ka...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0031-1276737
更新日期:2011-09-01 00:00:00
abstract:OBJECTIVE:The management of breech presentation may improve perinatal outcomes. The aim of this study was to synthesize and compare published evidence of four national guidelines on breech presentation. STUDY DESIGN:A descriptive review of four recently published national guidelines on breech presentation and external...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0039-1692391
更新日期:2020-09-01 00:00:00
abstract:OBJECTIVE:This article compares hemodynamic characteristics of neonates with hypoxic ischemic encephalopathy (HIE) receiving therapeutic hypothermia (TH) with normal versus abnormal brain magnetic resonance imaging (MRI). METHODS:Serial echocardiography (echo) was performed within 24 hours, after 48 to 72 hours of coo...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0038-1629900
更新日期:2018-08-01 00:00:00
abstract::The purpose of this study was to compare the delayed response to Bacillus Calmette-Guérin (BCG) immunization in preterm infants 31.4 to 34.6 weeks of age with full-terms infants by tuberculin test (tuberculin skin test with purified protein derivative [PPD]). One hundred newborns were studied from November 2000 to Apr...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-970080
更新日期:2007-03-01 00:00:00
abstract::With more than 20,000 fetal deaths occurring annually in the United States, accurate epidemiological data concerning fetal death offer the potential to develop interventions aimed at saving a considerable number of fetuses. Currently, fetal death rates are determined by dividing the number of deaths by total births. T...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-994589
更新日期:1994-07-01 00:00:00
abstract::Objectives This study aims to examine the relationship between hospital birth volume and multiple maternal morbidities among low-risk pregnancies in rural hospitals, urban non-teaching hospitals, and urban teaching hospitals, using a representative sample of U.S. hospitals. Study Design Using the 2011 Nationwide Inpat...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0035-1570380
更新日期:2016-05-01 00:00:00
abstract::One hundred twenty-one patients underwent an ultrasound examination within 48 hours of delivery to assess prospectively the reliability of the diagnosis of intrauterine growth retardation. Sonographic parameters examined included the abdominal circumference, sonographic estimate of fetal weight, the head to abdominal ...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-999622
更新日期:1989-10-01 00:00:00
abstract::The purpose of this study was to determine if placental abruption or previa in women with a history of a prior cesarean delivery (CD) can be predicted. A retrospective cohort study of pregnant women with previous CD was conducted in 17 centers between 1996 and 2000. Women developing placenta previa or abruption in the...
journal_title:American journal of perinatology
pub_type: 杂志文章,多中心研究
doi:10.1055/s-2007-981430
更新日期:2007-05-01 00:00:00
abstract:OBJECTIVE: This study aimed to review the feasibility of nasal high-frequency oscillatory ventilation (NHFOV) in preventing reintubation in preterm infants STUDY DESIGN: This is a retrospective cohort study of all premature newborn infants placed on NHFOV in a single-center neonatal intensive care unit. RESULTS: Twen...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0040-1718738
更新日期:2020-10-19 00:00:00
abstract::The purpose of this study was to determine the short-term outcome of newborns less than 30 weeks gestation when there is definite placental histologic chorioamnionitis. A retrospective analysis was performed of records of all neonates delivered at our institution from January 1989 through January 1999. This informatio...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2005-865020
更新日期:2005-04-01 00:00:00
abstract:OBJECTIVE:This study aimed to investigate factors that influence growth in infants with gastroschisis. STUDY DESIGN:Growth parameters at birth, discharge, 6, 12, and 18 months of age were collected from 42 infants with gastroschisis. RESULTS:The mean z-scores for weight, length, and head circumference were below norm...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0039-1693988
更新日期:2020-12-01 00:00:00
abstract::Periventricular leukomalacia, a condition characterized by hpoxic-ischemic infarction of deep cerebral white matter, can now be recognized by cranial sonography. The case presented here demonstrates the association of periventricular leukomalacia present at birth with intrauterine paroxysmal supraventricular tachycard...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-999826
更新日期:1986-01-01 00:00:00
abstract::Seven sociodemographic and behavioral factors that may explain the increased risk of preterm deliveries among black women were examined using data from a national sample of 5823 married mothers who responded to the 1980 National Natality Survey (NNS) Questionnaire. There was a twofold increase in the rate of preterm d...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-999412
更新日期:1991-09-01 00:00:00
abstract:BACKGROUND:Neonatal presentation of vein of Galen aneurysmal malformations (VGAMs) complicated by cardiac failure and pulmonary hypertension is frequently associated with a poor prognosis. Interventional neuroradiology with embolization can offer a chance for survival, although neurological damage can represent a limit...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0038-1666813
更新日期:2019-01-01 00:00:00
abstract::Nine patients with posthemipelvectomy with subsequent delivery of 13 living children are reported in the world's literature. This radical procedure is possible only in a modern age of intensive medical and surgical support. Additional cases can be expected in the future. We present two additional patients and three ch...
journal_title:American journal of perinatology
pub_type: 杂志文章,评审
doi:10.1055/s-2007-999616
更新日期:1989-07-01 00:00:00
abstract::The presence of the maternal warm antibody in pregnancy should not be ignored. As there is risk of both maternal and fetal anemia, both patients need to be followed for the development of such. Serial complete blood counts in the mother and treatment if significant fetal anemia develops should be considered. Serial am...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-994196
更新日期:1996-01-01 00:00:00
abstract::Chorioamnionitis has generally been thought to be a contraindication to attempting a delayed interval delivery in a multiple gestation. We present a twin gestation in which a delay of 88 days between the birth of the two infants occurred. Chorioamnionitis observed immediately after the delivery of Twin A was successfu...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-993962
更新日期:1998-06-01 00:00:00
abstract:OBJECTIVE:The aim of this study is to assess if women with arrested preterm labor (PTL) have an increased risk of preterm delivery (PTD) compared with healthy pregnant women, and if digital examination, fetal fibronectin (fFn) and cervical length (CL) are prognostic markers for PTD after arrested PTL. STUDY DESIGN:Pro...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0034-1374818
更新日期:2015-01-01 00:00:00
abstract::Anti-Cw is an uncommon cause of clinically significant hemolytic disease of the newborn (HDN). We report an unusually severe case of HDN due to anti-Cw that required phototherapy and exchange transfusion. We also describe a novel PCR-RFLP method for Cw typing of fetal genomic DNA that was used for prenatal diagnosis i...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-993872
更新日期:1999-01-01 00:00:00
abstract::Novel coronavirus disease 2019 (COVID-19) infection occurring during pregnancy is associated with an increased risk of preterm delivery. This case report describes successful treatment of preterm labor during acute COVID-19 infection. Standard treatment for preterm labor may allow patients with acute COVID-19 infectio...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0040-1709993
更新日期:2020-06-01 00:00:00
abstract:OBJECTIVES:The purpose of this article is to review all randomized control trials (RCTs) that have looked at the health effects of yoga on pregnancy, and to present their evidence on the specific ways in which pregnant women, and their infants can benefit from yoga intervention. The purpose is also to determine whether...
journal_title:American journal of perinatology
pub_type: 杂志文章,评审
doi:10.1055/s-0034-1396701
更新日期:2015-05-01 00:00:00
abstract:OBJECTIVE:This study aims to determine risk factors for rehospitalization in extremely premature infants. STUDY DESIGN:A retrospective cohort study of 157 infants born < 29 weeks' gestational age assessing risk factors for rehospitalization through 2 years of life. RESULTS:Multivariable logistic regression showed tha...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0035-1555123
更新日期:2016-01-01 00:00:00
abstract::There is increasing concern about Chlamydia trachomatis infection during pregnancy, because of reports of increased maternal, fetal, and neonatal risks. Amniotic fluid is known to possess antibacterial activity and has recently been shown to inhibit formation of chlamydial inclusions in McCoy cell culture. To further ...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-999341
更新日期:1991-01-01 00:00:00
abstract::We evaluated the clinical significance of late decelerations (LD) of intrapartum fetal heart rate (FHR) monitoring to detect low pH (< 7.1) in low-risk pregnancies. We selected two secondary and two tertiary-level institutions where 10,030 women delivered. Among them, 5522 were low-risk pregnancies. The last 2 hours o...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2004-837272
更新日期:2005-01-01 00:00:00
abstract::In Finland a nationwide free prenatal care system was mandated by law in 1944. At present, 99.9% of Finland's pregnant women use it. The primary aim is to provide advice and care to all women in local centers and to identify pregnant women exhibiting risk factors and refer them to specialized prenatal units located in...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-999581
更新日期:1989-04-01 00:00:00
abstract::We investigated body mass index (BMI) and weight gain among pregnant women (ages 14 to 25) and assessed the relationship of BMI and weight gain on birth outcomes. We performed a secondary analysis of 841 women enrolled in a randomized controlled trial receiving prenatal care in two university-affiliated clinics. Almos...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0028-1110088
更新日期:2009-05-01 00:00:00
abstract::Chorioamnionitis contributes to neonatal and maternal morbidity and mortality. We aimed to evaluate of the impact of clinical and histological chorioamnionitis on mortality and morbidity of preterm infants. Maternal and neonatal data were collected in a retrospective cohort of preterm infants less than 30 weeks' gesta...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0032-1321501
更新日期:2013-01-01 00:00:00
abstract:OBJECTIVE:To determine the accuracy of clinically estimated fetal weight (CEFW) in patients with gestational diabetes (GDM), pregestational diabetes (DM), and obesity. STUDY DESIGN:This is a retrospective analysis of Consortium of Safe Labor data. Subjects were classified into six groups: DM, DM and obese, GDM, GDM an...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0033-1334450
更新日期:2014-01-01 00:00:00