Abstract：
OBJECTIVE: This article aims to compare long-term neurodevelopmental and health outcomes of twins born at 34 weeks or later, based on the presence of small for gestational age (SGA). STUDY DESIGN: This study is a mail-based survey of twin gestations delivered by a single practice. We compared twins with and without SGA delivered at ≥34 weeks. There were two primary outcomes for this study: a composite of major adverse outcomes (death; cerebral palsy; necrotizing enterocolitis; chronic renal, heart, or lung disease) and a composite of minor adverse outcomes (learning disability, speech therapy, occupational therapy, physical therapy). Regression analysis was performed to control for clustering of outcomes within twin pairs. RESULTS: A total of 712 children were included. Comparing twins with birthweights <10% to ≥10%, there were no significant differences in rates of composite major morbidities (3.2 vs. 1.4%, p = 0.109) or composite minor morbidities (43.6 vs. 39.3%, p = 0.279). Comparing twins with birthweights <5% to ≥5%, the rates of major morbidities were low in both groups, but significantly higher in the group with birthweights <5% (4.4 vs. 1.6%, p = 0.046). There were no significant differences seen in the composite minor morbidities (46.7 vs. 39.7%, p = 0.134). Twins with birthweights <5% were significantly more likely to have childhood cardiac disease (2.9 vs. 0.7%, p = 0.041). CONCLUSION: Twins with SGA <10% born at ≥34 weeks have similar long-term neurodevelopmental and health outcomes compared with twins with normal birthweights. Birthweight less than 5th percentile is associated with an increased risk of major morbidity, specifically cardiac disease, but the absolute risk is low.
journal_name
Am J Perinatoljournal_title
American journal of perinatologyauthors
Herlihy N,Odom E,Cohen N,Stroustrup A,Rebarber A,Fox NSdoi
10.1055/s-0037-1607043subject
Has Abstractpub_date
2018-02-01 00:00:00pages
254-261issue
3eissn
0735-1631issn
1098-8785journal_volume
35pub_type
杂志文章abstract：:We compared lymphocyte subsets and cytokine responses to bacteria among term, preterm infants, and adults. Lymphocyte subset percentages in cord blood (22 preterm, 27 term neonates) and peripheral blood from 21 adults and cytokine/chemokine interleukin (IL)-6, IL-8, IL-10, IL-12, interferon gamma (IFN gamma) responses...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0029-1220788
更新日期：2009-10-01 00:00:00
abstract：OBJECTIVE: This study aimed to determine whether outcomes differed between infants enrolled in the PREMOD2 trial and those otherwise eligible but not enrolled, and whether the use of waiver effected these differences. STUDY DESIGN: The multicenter PREMOD2 (PREmature infants receiving Milking Or Delayed cord clamping) ...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0040-1719184
更新日期：2020-11-03 00:00:00
abstract：:This is the first reported case in which a Logothetopulos pack was utilized to achieve pelvic hemostasis in a patient requiring a cesarean hysterectomy for placenta accreta with postpartum hemorrhage. The Logothetopulos pack is an easily constructed gauze tamponade method that proved to be life-saving in this case. ...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-999514
更新日期：1990-10-01 00:00:00
abstract：:The objective of this article is to test whether the concentration of potentially oxidizable lipids (polyunsaturated fatty acids [PUFA], total and free cholesterol) and lipophilic antioxidants (plasmalogens, vitamin E) in the fetal lung correlate with lung maturation (P/S ratio). In amniotic fluid palmitic/stearic aci...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-993952
更新日期：1998-05-01 00:00:00
abstract：:It has been suggested that vibroacoustic stimulation might be stressful to the fetus. The present study was designed to evaluate whether the stimulus induces passage of meconium in labor. Patients in labor at term with healthy fetuses and intact membranes were randomized to a vibroacoustic stimulation or sham test. Th...
journal_title：American journal of perinatology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1055/s-2007-994297
更新日期：1996-02-01 00:00:00
abstract：:This communication examines the diagnostic value of the leukocyte esterase activity (LEA) test in the detection of intra-amniotic infection. Amniotic fluid from 171 consecutive patients with premature rupture of membranes (n = 149) and preterm labor (n = 22) was obtained through amniocentesis. Gram stain, bacterial an...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-999657
更新日期：1988-01-01 00:00:00
abstract：OBJECTIVE: The study objective was to assess the correlation between hypernatremia during the first week of life and neurodevelopmental outcomes at 18 months of corrected age in premature infants. STUDY DESIGN: A retrospective observational study of preterm infants born at less than 32 weeks of gestation who had a neu...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0040-1716845
更新日期：2020-09-24 00:00:00
abstract：OBJECTIVE:The Misgav-Ladach technique is recommended worldwide to perform cesarean sections but there is no consensus about the appropriate technique to use in patients with previous cesarean sections. This study evaluated the feasibility of the Misgav-Ladach technique in patients with previous cesarean sections. STUD...
journal_title：American journal of perinatology
pub_type： 临床试验,杂志文章
doi：10.1055/s-0032-1323580
更新日期：2013-03-01 00:00:00
abstract：:Persistent fetal bradycardia is rarely encountered during pregnancy. When it is associated with a complete atrio-ventricular (A-V) block, it may prove dangerous to the fetus or newborn. The prenatal diagnosis is vital because it necessitates close follow-up during pregnancy to detect fetal compromise and proper prepar...
journal_title：American journal of perinatology
pub_type： 杂志文章,评审
doi：10.1055/s-2007-994152
更新日期：1997-07-01 00:00:00
abstract：:Meningitis is the major pathologic manifestation of Listeria monocytogenes in the United States. Despite the fact that this organism has a well-known predilection for individuals who are pregnant or immunocompromised, to date, maternal listeric meningitis remains an unreported entity in the English literature. The aut...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-1000029
更新日期：1984-07-01 00:00:00
abstract：:The purpose of this study was to compare the AmniSure rapid immunoassay with standard methods for diagnosing rupture of fetal membranes. Patients presenting with signs/symptoms of membrane rupture between 15 and 42 weeks of gestation were invited to participate. Standard/control methods were performed to establish a d...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2005-870896
更新日期：2005-08-01 00:00:00
abstract：:Interest in centralized monitoring in labor and delivery units is growing because it affords the opportunity to monitor multiple patients simultaneously. However, a long history of research on sustained attention reveals these types of monitoring tasks can be problematic. The goal of the present experiment was to exam...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0030-1268718
更新日期：2011-06-01 00:00:00
abstract：:The purpose of this study was to examine the association between intrapair birthweight discordance and fetal and neonatal mortality. This was a historical cohort study, using the Statistics Canada linked birth-infant death file. Twin births in Canada (excluding Ontario) for the period 1986-1997 were studied. Outcome m...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2005-870899
更新日期：2005-07-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Congenital pulmonary airway malformation (CPAM) is a group of rare congenital malformations of the lung and airways. Lung ultrasound (LU) is increasingly used to diagnose neonatal respiratory diseases since it is quick, easy to learn, and radiation-free, but no formal data exist for congenital ...
journal_title：American journal of perinatology
pub_type： 杂志文章,多中心研究
doi：10.1055/s-0038-1645861
更新日期：2018-10-01 00:00:00
abstract：OBJECTIVE:Neonatal biomarkers of inflammation were examined in relation to early neurodevelopment and gait in very-low-birth-weight (VLBW) preterm children. We hypothesized that preterm infants exposed to higher levels of neonatal inflammation would demonstrate lower scores on Bayley Scales of Infant Toddler Developmen...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0035-1557106
更新日期：2016-01-01 00:00:00
abstract：OBJECTIVE:The aim of this study is to examine the hypothesis that prolonged rupture of membranes (PROM) is associated with increased cord blood erythropoietin (EPO) concentrations, proportional to the duration of ruptured membranes. STUDY DESIGN:This study is a prospective, cross-sectional, observational (nonintervent...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0034-1384643
更新日期：2015-03-01 00:00:00
abstract：:Molecular amplification of parvovirus B19 DNA in an amniotic fluid sample was used to confirm the etiologic agent of a case with fetal hydrops. The polymerase chain reaction (PCR) method used is easy and fast to perform. We have a 2-year experience on its use in clinical parvovirus B19 diagnosis. The results are avail...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-994518
更新日期：1995-11-01 00:00:00
abstract：:Infants born from mothers with antiphospholipid antibody (aPL) -positive autoimmune disease were prospectively evaluated for anticardiolipin and anti-beta2 glycoprotein I antibodies (group 1) and for growth and neurological development. The results were compared with those obtained from two age-matched control groups ...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2006-939533
更新日期：2006-05-01 00:00:00
abstract：:We present a case of a premature infant with early-onset necrotizing enterocolitis as the presenting symptom of familial dysautonomia. The diagnosis of familial dysautonomia in the neonatal period is usually rare and difficult, because many of the symptoms may be mild or nonspecific, whereas other characteristic signs...
journal_title：American journal of perinatology
pub_type： 杂志文章,评审
doi：10.1055/s-2005-871525
更新日期：2005-10-01 00:00:00
abstract：:The objective of this study was to perform antiphospholipid antibody screening in women with chronic hypertension to assess whether the presence of such antibodies is associated with adverse pregnancy outcome. Serum for anticardiolipin antibodies and lupus anticoagulant was obtained in pregnant women with chronic hype...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2004-829870
更新日期：2004-07-01 00:00:00
abstract：:The novel coronavirus disease 2019 (COVID-19) pandemic has resulted in changes to perinatal and neonatal care, concentrating on minimizing risks of transmission to the newborn and health care staff while ensuring medical care is not compromised for both mother and infant. Current recommendations on infant care and fee...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0040-1716506
更新日期：2020-11-01 00:00:00
abstract：:Pulmonary hypoplasia is lethal in its most severe form; in less severe cases the clinical course is protracted, usually resulting in chronic lung disease. A case of unexpected survival of an infant with clinical and radiologic evidence of pulmonary hypoplasia, in whom dexamethasone was administered, is presented. Poss...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-999375
更新日期：1991-05-01 00:00:00
abstract：OBJECTIVE:To compare the obstetric recommendations in American Congress of Obstetricians and Gynecologists (ACOG) practice bulletins (PB) with similar topics in UpToDate (UTD). STUDY DESIGN:We accessed all obstetric PB and cross-searched UTD (May 1999-May 2013). We analyzed only the PB which had corresponding UTD chap...
journal_title：American journal of perinatology
pub_type： 杂志文章,评审
doi：10.1055/s-0034-1396684
更新日期：2015-04-01 00:00:00
abstract：:Infection-related neonatal mortality due to omphalitis in developing country home births is an important public health problem. Three cluster randomized trials of 4% chlorhexidine applied to the umbilical cord stump from once to multiple times in the days following a home birth have evaluated this intervention compare...
journal_title：American journal of perinatology
pub_type： 杂志文章,评审
doi：10.1055/s-0032-1329695
更新日期：2013-09-01 00:00:00
abstract：:I developed a single equation that simulated previously published growth charts for very low-birth-weight infants, using birth weight as the only variable. The intent of this study was to validate the equation using infants admitted to our neonatal intensive care unit (NICU) and to determine if this equation could be ...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-993914
更新日期：1998-02-01 00:00:00
abstract：OBJECTIVE:The definition of postpartum hemorrhage (PPH) was developed more than 50 years ago. Since then, the obstetric population has changed dramatically. We sought to determine how well we estimated blood loss (EBL) and find thresholds predicting need for transfusion. STUDY DESIGN:We performed a prospective cohort ...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0035-1552940
更新日期：2015-11-01 00:00:00
abstract：:A sudden and unexpected death, at 26 hours of age, of a term infant with no identifiable risk factors either in the prenatal or in the immediate neonatal period is described. The most remarkable postmortem findings were confined to the lungs, which had many areas of aspirated amniotic fluid, as well as extensive areas...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-999592
更新日期：1989-07-01 00:00:00
abstract：OBJECTIVE:Postpartum higher-dose oxytocin (80 U) compared with lower dose (10 U) given in 500 mL over 1 hour does not decrease postpartum hemorrhage (PPH) requiring treatment, but reduces the risk of hematocrit decline ≥ 6% among women delivering vaginally. Our objective was to evaluate whether the duration of administ...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0034-1370347
更新日期：2014-11-01 00:00:00
abstract：:Diagnostic ultrasonography has given us the opportunity to diagnose several congenital malformations in utero. Skeletal dysplasias is a heterogeneous group of disorders of the skeleton. Although disorders of bone growth are often diagnosed in utero, it is usually a general diagnosis because the exact syndrome cannot b...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-994638
更新日期：1993-03-01 00:00:00
abstract：:Based on small studies and not on statistically valid clinical trials, guidelines for neonatal transfusions remain controversial and practices vary greatly. Premature infants and critically ill neonates in the neonatal intensive care unit (NICU) often require blood transfusions and extremely preterm neonates receive a...
journal_title：American journal of perinatology
pub_type： 杂志文章,评审
doi：10.1055/s-0036-1586106
更新日期：2016-09-01 00:00:00
