Abstract:
OBJECTIVE:The aim of this study is to examine the hypothesis that prolonged rupture of membranes (PROM) is associated with increased cord blood erythropoietin (EPO) concentrations, proportional to the duration of ruptured membranes. STUDY DESIGN:This study is a prospective, cross-sectional, observational (noninterventional) cohort study of mother-infant pairs. Criteria for inclusion were as follows: active labor with or without ruptured membranes and vaginally delivered neonates. Excluded were infants with major factors known to be associated with a potential increase in fetal erythropoiesis. RESULTS:A total of 40 mother-infant pairs were recruited. EPO was not influenced by duration of ruptured membranes and significantly correlated only with maternal body mass index. CONCLUSION:Cord blood concentrations of EPO do not appear to be significantly affected by the duration of ruptured membranes. We speculate that erythropoiesis is upregulated in PROM by mechanisms that involve the production of cytokines and are not EPO driven.
journal_name
Am J Perinatoljournal_title
American journal of perinatologyauthors
Barak S,Mimouni FB,Stern R,Cohen N,Goldstein DB,Marom Rdoi
10.1055/s-0034-1384643subject
Has Abstractpub_date
2015-03-01 00:00:00pages
317-20issue
4eissn
0735-1631issn
1098-8785journal_volume
32pub_type
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journal_title:American journal of perinatology
pub_type: 杂志文章
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journal_title:American journal of perinatology
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journal_title:American journal of perinatology
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journal_title:American journal of perinatology
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journal_title:American journal of perinatology
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journal_title:American journal of perinatology
pub_type: 杂志文章,评审
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pub_type: 杂志文章,随机对照试验
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journal_title:American journal of perinatology
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doi:10.1055/s-0031-1295659
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journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-994691
更新日期:1993-01-01 00:00:00
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journal_title:American journal of perinatology
pub_type: 杂志文章
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更新日期:1990-01-01 00:00:00
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更新日期:2017-01-01 00:00:00
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pub_type: 杂志文章,多中心研究
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pub_type: 杂志文章
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pub_type: 杂志文章
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journal_title:American journal of perinatology
pub_type: 杂志文章
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pub_type: 杂志文章
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