Abstract：
BACKGROUND:Neonatal presentation of vein of Galen aneurysmal malformations (VGAMs) complicated by cardiac failure and pulmonary hypertension is frequently associated with a poor prognosis. Interventional neuroradiology with embolization can offer a chance for survival, although neurological damage can represent a limitation. OBJECTIVE:This article determines if aggressive intensive care and drug management of cardiac failure before urgent embolization can influence morbidity and mortality. PATIENTS AND METHODS:Twelve infants (7 boys, 5 girls) were diagnosed with symptomatic vein of Galen malformations in the neonatal period during the period 2000 to 2014. Due to high output cardiac failure, endovascular treatment was attempted as soon as stabilization was achieved. RESULTS:Endovascular procedures successfully reverted cardiac failure in 5 patients who survived without significant neurological damage, while in 7 patients the causes of death were refractory cardiac failure, multiorgan failure, and severe brain damage. Bidimensional echocardiography assessment was performed at presentation and after early embolization procedures. CONCLUSION:Aggressive intensive care approach to heart failure and pulmonary hypertension leading to early neurointervention results in good survival rates with low morbidity even in cases of high-risk neonatal VGAM. Combined hemodynamic treatment can improve outcome in neonates with cardiac failure secondary to VGAM, although there is the risk of precipitating systemic hypoperfusion and renal failure. A moderate prematurity may not prevent both interventional approach and good outcome.
journal_name
Am J Perinatoljournal_title
American journal of perinatologyauthors
De Rosa G,De Carolis MP,Tempera A,Pedicelli A,Rollo M,Morena TC,Luca E,De Luca D,Conti G,Piastra Mdoi
10.1055/s-0038-1666813subject
Has Abstractpub_date
2019-01-01 00:00:00pages
169-175issue
2eissn
0735-1631issn
1098-8785journal_volume
36pub_type
杂志文章abstract：:Discordancy in twins is generally described as a weight difference between the fetuses of 15 to 25% and its prevalence in normal twin gestations is estimated at 15 to 29%. The present study was performed in order to determine the frequency of discordant newborns in uncomplicated triplet gestations. One hundred and fou...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-994724
更新日期：1993-05-01 00:00:00
abstract：: ...
journal_title：American journal of perinatology
pub_type： 杂志文章,已发布勘误
doi：10.1055/s-0038-1660792
更新日期：2018-07-01 00:00:00
abstract：:A sudden and unexpected death, at 26 hours of age, of a term infant with no identifiable risk factors either in the prenatal or in the immediate neonatal period is described. The most remarkable postmortem findings were confined to the lungs, which had many areas of aspirated amniotic fluid, as well as extensive areas...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-999592
更新日期：1989-07-01 00:00:00
abstract：:Neonatal alloimmune thrombocytopenia (NAIT) is the most common cause of severe thrombocytopenia in an otherwise healthy newborn. The most serious complication is intracranial hemorrhage, which can occur either in the fetus or the newborn. Despite the known serious sequelae, both antenatal management and neonatal treat...
journal_title：American journal of perinatology
pub_type： 杂志文章,评审
doi：10.1055/s-0030-1263296
更新日期：2011-02-01 00:00:00
abstract：:We compared perinatal outcomes between live-born nonisolated and isolated omphaloceles diagnosed during a prenatal ultrasound. Fetuses (n = 86) with omphalocele were identified between 1995 and 2007 at a single institution. Inclusion criteria were an omphalocele >14 weeks' gestation, available fetal and/or neonatal ka...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0031-1276737
更新日期：2011-09-01 00:00:00
abstract：:Phosphatidylglycerol (PG) in amniotic fluid was quantitatively measured by thin-layer chromatography (TLC) in 941 amniotic fluid samples and related to the presence or absence of respiratory distress syndrome (RDS) in neonates born within 7 days of the amniocentesis. In 639 case tests with PG 1 nmol/ml or more of amni...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-994666
更新日期：1992-01-01 00:00:00
abstract：:Cord blood gas determinations were made on arterial and venous blood from 78 babies weighing less than 2000 gm at birth, including 52 weighing 1500 gm or less. Correlations were made with Apgar scores and intrapartum events as well as with birthweight (BW) and gestational age (GA). Significant differences were seen be...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-999925
更新日期：1985-04-01 00:00:00
abstract：OBJECTIVE: This study aimed to identify differences in sequential integrated screening and early ultrasound markers in monochorionic/diamniotic (MC/DA) pregnancies complicated by twin-to-twin transfusion syndrome (TTTS) and unequal placental sharing (UPS). STUDY DESIGN: Retrospective cohort study of MC/DA pregnancies ...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0040-1718371
更新日期：2020-10-08 00:00:00
abstract：:A patient with a homozygous marital partner had three progressively less seriously involved RH-positive babies after a fetal demise due to erythroblastosis. Only the first of the three required fetal transfusions. All were Rh genotypically identical. The case is presented for interest and to illustrate an exception to...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-999655
更新日期：1988-01-01 00:00:00
abstract：:Limited research in young adults and immature animals suggests a detrimental effect of tobacco on bone during growth. We aimed to determine the adverse effects of maternal nicotine exposure during pregnancy and lactation on neonatal rat bone development, and to determine a protective effect of ascorbic acid. Gravid ra...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2006-951287
更新日期：2006-10-01 00:00:00
abstract：OBJECTIVE:The aim of the article is to review the effectiveness of neonatal noninvasive high-frequency ventilation (NIHFV) in preventing endotracheal mechanical ventilation. STUDY DESIGN:Retrospective case series including all 79 instances of NIHFV use at four participating centers between July 2010 and September 2012...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0034-1381317
更新日期：2015-02-01 00:00:00
abstract：:Our objective was to describe the change in the level of troponin I in patients who undergo a vaginal or cesarean delivery. We obtained troponin I levels on admission and 1 hour after delivery in women undergoing vaginal and cesarean deliveries. Exclusion criteria included <37 weeks' gestation, a history of cardiac di...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2004-820507
更新日期：2004-01-01 00:00:00
abstract：:Chorioamnionitis has generally been thought to be a contraindication to attempting a delayed interval delivery in a multiple gestation. We present a twin gestation in which a delay of 88 days between the birth of the two infants occurred. Chorioamnionitis observed immediately after the delivery of Twin A was successfu...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-993962
更新日期：1998-06-01 00:00:00
abstract：OBJECTIVE:To determine the risk of gestational diabetes mellitus (GDM) and insulin resistance (IR) in obesity defined by body mass index (BMI), waist-to-hip ratio (WHR), or both combined. METHODS:Secondary analysis of a randomized multicenter trial of antioxidant supplementation versus placebo in nulliparous low-risk ...
journal_title：American journal of perinatology
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1055/s-0035-1562928
更新日期：2016-01-01 00:00:00
abstract：:In insulin dependent diabetic (IDDM) gestations, fetal pulmonary maturity is delayed in the presence of suboptimal glycemic control. Serum glycosylated hemoglobin (HbA1c) provides a means of assessing glycemic control. We evaluated maternal HbA1c in IDDM pregnancies at term undergoing amniocentesis for lung maturity t...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-993868
更新日期：1999-01-01 00:00:00
abstract：OBJECTIVE: Previous analyses of neonatal intensive care units (NICU) antimicrobial stewardship programs have identified key contributors to overall antibiotic use, including prolonged empiric therapy >48 hours for early-onset sepsis (EOS). However, most were performed in mixed NICU settings with onsite birthing units, ...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0040-1722600
更新日期：2021-01-17 00:00:00
abstract：:Surfactants have been routinely used since 1990 for the treatment of respiratory distress syndrome (RDS). The use of surfactant has coincided with a decrease in mortality in infants due to RDS. This review focuses on clinical aspects of surfactant use. New information, particularly effects of ventilatory styles on sur...
journal_title：American journal of perinatology
pub_type： 杂志文章,评审
doi：10.1055/s-2000-13445
更新日期：2000-01-01 00:00:00
abstract：:We describe a case of transient hyperinsulinism in an asphyxiated newborn infant with hypoglycemia. Although hypoglycemia in birth asphyxiated infants is generally attributed to depletion of glycogen stores, we observed severe hyperinsulinism associated with the hypoglycemia. The hypoglycemia was refractory to high gl...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2001-15504
更新日期：2001-06-01 00:00:00
abstract：:Nine patients with posthemipelvectomy with subsequent delivery of 13 living children are reported in the world's literature. This radical procedure is possible only in a modern age of intensive medical and surgical support. Additional cases can be expected in the future. We present two additional patients and three ch...
journal_title：American journal of perinatology
pub_type： 杂志文章,评审
doi：10.1055/s-2007-999616
更新日期：1989-07-01 00:00:00
abstract：:Periventricular leukomalacia, a condition characterized by hpoxic-ischemic infarction of deep cerebral white matter, can now be recognized by cranial sonography. The case presented here demonstrates the association of periventricular leukomalacia present at birth with intrauterine paroxysmal supraventricular tachycard...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-999826
更新日期：1986-01-01 00:00:00
abstract：:Type 1 cystic sacrococcygeal teratomas, usually associated with good outcome following neonatal resection, must be differentiated at the time of prenatal diagnosis from sonographically similar meningomyeloceles, which carry a grave prognosis. We present an unusual case in which color Doppler imaging assisted correct m...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-994089
更新日期：1997-01-01 00:00:00
abstract：OBJECTIVE:To evaluate the role of first-trimester uterine artery Doppler in the prediction of recurrent preeclampsia (PE). METHODS:Uterine artery pulsatility index (UtPI) was measured at 11 to 13 weeks' gestation in 1,810 women with singleton pregnancies who had developed PE in a previous pregnancy. They were categori...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0033-1338172
更新日期：2014-02-01 00:00:00
abstract：:The antioxidant enzyme paraoxonase 1 is a marker of oxidative stress and has been implicated in the pathogenesis of preeclampsia. Our objective was to determine if an association exists between low paraoxonase 1 activity at midgestation and the development of preeclampsia. We conducted a case-control study of 50 women...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0029-1236438
更新日期：2010-03-01 00:00:00
abstract：:First-trimester prenatal diagnosis was offered to 104 twin pregnancies mainly for advanced maternal age and cytogenetic evaluation of a new fertilization technique. Chorionic villus sampling (CVS) was performed transcervically (35%), transabdominally (23%), or by combination of these two techniques (42%). Although no ...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-994380
更新日期：1996-10-01 00:00:00
abstract：:We describe the neuropathologic procedure utilized in the Stillbirth Collaborative Research Network (SCRN), focusing on the examination of central nervous system (CNS) in stillbirth (SB). The SCRN was organized to perform a case-control study to determine the scope and causes of SB. Pathologists at all the participati...
journal_title：American journal of perinatology
pub_type： 杂志文章,多中心研究
doi：10.1055/s-0031-1284229
更新日期：2011-12-01 00:00:00
abstract：OBJECTIVE:To determine epidemiology and clinical characteristics of infants with methicillin-susceptible (MSSA) and -resistant Staphylococcus aureus (MRSA) in a level III neonatal intensive care unit (NICU). STUDY DESIGN:All NICU admissions (2001 to 2008) with any positive S. aureus culture were included as cases. Cas...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0032-1304819
更新日期：2012-06-01 00:00:00
abstract：:This prospective study was performed to determine a way to improve conventional transcutaneous bilirubinometry results in healthy term newborn infants. In 118 infants during phototherapy (group A), and in 118 infants without phototherapy (group B), bilirubin determinations were done in duplicate using the Minolta AirS...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2005-867087
更新日期：2005-05-01 00:00:00
abstract：OBJECTIVE:The objective of this study was to evaluate the clinical characteristics of neonates with hydrops fetalis to improve recognition of the disease. PATIENTS AND METHODS:The clinical data of 10 neonates with hydrops fetalis were retrospectively studied. Prenatal characteristics, causes, clinical features, and pr...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0035-1552934
更新日期：2015-11-01 00:00:00
abstract：OBJECTIVE: According to the most recent metanalysis, the best way to establish safe enteral feeding in preterm babies using nasogastric or orogastric tubes is still not well understood. This study aimed to determine the effects of bolus nasal tubes versus bolus orogastric tubes on the time required to reach full entera...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0040-1713865
更新日期：2020-07-03 00:00:00
abstract：OBJECTIVE:Postpartum higher-dose oxytocin (80 U) compared with lower dose (10 U) given in 500 mL over 1 hour does not decrease postpartum hemorrhage (PPH) requiring treatment, but reduces the risk of hematocrit decline ≥ 6% among women delivering vaginally. Our objective was to evaluate whether the duration of administ...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0034-1370347
更新日期：2014-11-01 00:00:00
